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Results for "

Caco-2 intestinal epithelial cells

" in MedChemExpress (MCE) Product Catalog:

11

Inhibitors & Agonists

1

Fluorescent Dyes

1

Biochemical Assay Reagents

3

Natural
Products

1

GMP Molecules

Targets Recommended:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-W011053
    Neotame

    		Taste Receptor Apoptosis Drug Derivative Metabolic Disease
    Neotame is a derivative of Aspartame (HY-B0361) and is a flavor enhancer and low-caloric, non-nutritive, high-intensity artificial sweetener that is 7000-13,000 times sweeter than sugar. Neotame causes intestinal epithelial cell death at high concentrations. Neotame induces Apoptosis of Caco-2 cells .
    Neotame
  • HY-W127512
    5β-Cholanic acid
    1 Publications Verification

    		 Drug Intermediate Others
    5β-Cholanic acid is a hydrophobic modifier used to modify polymer carriers. 5β-Cholanic acid can improve the acid stability, cell penetration efficiency and drug sustained release ability of nanocarriers, and optimize the oral effectiveness of delivered molecules. 5β-Cholanic acid can covalently bind to Glycol chitosan (GC) to form a GC-CA conjugate, which optimizes the hydrophobic anchoring ability of nanoparticles and enables them to be stably adsorbed on the surface of PLGA nanoparticles. Such nanoparticles can resist dissociation in the gastric acid environment and maintain positive charge to enhance endocytic uptake by intestinal epithelial cells (such as Caco-2 cells). 5β-Cholanic acid can be used in the development of drug delivery systems .
    5β-Cholanic acid
  • HY-W011053GL
    Neotame (GMP Like)

    		Taste Receptor Apoptosis Drug Derivative Metabolic Disease
    Neotame (GMP Like) is the GMP Like class Neotame (HY-W011053) that can be used as pharmaceutical excipients. Neotame is a derivative of Aspartame (HY-B0361) and is a flavor enhancer and low-caloric, non-nutritive, high-intensity artificial sweetener that is 7000-13,000 times sweeter than sugar. Neotame causes intestinal epithelial cell death at high concentrations. Neotame induces Apoptosis of Caco-2 cells .
    Neotame (GMP Like)
  • HY-W011053R
    Neotame (Standard)

    		Apoptosis Drug Derivative Reference Standards Metabolic Disease
    Neotame (Standard) is the analytical standard of Neotame (HY-W011053). This product is intended for research and analytical applications. Neotame is a derivative of Aspartame (HY-B0361) and is a flavor enhancer and low-caloric, non-nutritive, high-intensity artificial sweetener that is 7000-13,000 times sweeter than sugar. Neotame causes intestinal epithelial cell death at high concentrations. Neotame induces Apoptosis of Caco-2 cells .
    Neotame (Standard)
  • HY-W127512R
    5β-Cholanic acid (Standard)

    		Drug Intermediate Reference Standards Others
    5β-Cholanic acid is a hydrophobic modifier used to modify polymer carriers. 5β-Cholanic acid can improve the acid stability, cell penetration efficiency and drug sustained release ability of nanocarriers, and optimize the oral effectiveness of delivered molecules. 5β-Cholanic acid can covalently bind to Glycol chitosan (GC) to form a GC-CA conjugate, which optimizes the hydrophobic anchoring ability of nanoparticles and enables them to be stably adsorbed on the surface of PLGA nanoparticles. Such nanoparticles can resist dissociation in the gastric acid environment and maintain positive charge to enhance endocytic uptake by intestinal epithelial cells (such as Caco-2 cells). 5β-Cholanic acid can be used in the development of drug delivery systems .
    5β-Cholanic acid (Standard)
  • HY-N18952
    Heparin disaccharide II-S trisodium

    		Interleukin Related Inflammation/Immunology
    Heparin disaccharide II-S trisodium (Compound HSH-9) is a heparin-derived disaccharide. Heparin disaccharide II-S trisodium inhibits the spontaneous secretion of proinflammatory mediators IL-8 and IL-1β in intestinal epithelial cells at the post-transcriptional stage .
    Heparin disaccharide II-S trisodium
  • HY-N18954
    Heparin disaccharide III-S trisodium

    		Interleukin Related Inflammation/Immunology
    Heparin disaccharide III-S trisodium (Compound SHH-7) is a heparin-derived disaccharide. Heparin disaccharide III-S trisodium acts as an inhibitor of spontaneous IL-8 and IL-1β secretion by intestinal epithelial cells. Heparin disaccharide III-S trisodium functions at the post-translational stage and does not reduce mRNA or intracellular mediator levels .
    Heparin disaccharide III-S trisodium
  • HY-N18953
    Heparin disaccharide I-H trisodium

    		Interleukin Related Inflammation/Immunology
    Heparin disaccharide I-H trisodium (Compound SHS-5) is a heparin-derived disaccharide. Heparin disaccharide I-H trisodium blocks the spontaneous secretion of IL-8 and IL-1β in intestinal epithelial cells at the post-translational stage without reducing mRNA expression levels or intracellular contents. Heparin disaccharide I-H trisodium exhibits dose-dependent anti-inflammatory activity in intestinal epithelial cell models .
    Heparin disaccharide I-H trisodium
  • HY-181487
    FAK activator-1

    		FAK Inflammation/Immunology
    FAK activator-1 is a FAK activator and mucosal healing inducer.FAK activator-1 increases FAK phosphorylation at Tyr-397, promoting FAK activation.FAK activator-1 promotes mucosal healing.FAK activator-1 can be used for the research of nsaid-associated gastrointestinal mucosal injury .
    FAK activator-1
  • HY-183726
    PknB-IN-3

    		Bacterial Ser/Thr Kinase Infection
    PknB-IN-3 is a Mycobacterium tuberculosis Protein kinase B (PknB) inhibitor with an IC50 of 0.06 μM. PknB-IN-3 inhibits growth of Mycobacterium tuberculosis and can be used for the research of tuberculosis .
    PknB-IN-3
  • HY-183370
    JAK2/STAT3-IN-2

    		JAK STAT Interleukin Related Inflammation/Immunology
    JAK2/STAT3-IN-2 is an orally active JAK2/STAT3 inhibitor. JAK2/STAT3-IN-2 inhibits the phosphorylation of tyrosine residues in JAK2 and STAT3, blocks downstream signal transduction, disrupts the dimerization and nuclear translocation of STAT3, and suppresses pro-inflammatory transcriptional activity. JAK2/STAT3-IN-2 inhibits the expression of IL-17A and IL-17F, reduces immune cell infiltration, and inhibits the production of NO simultaneously. JAK2/STAT3-IN-2 exerts a protective effect in a mouse model of ulcerative colitis induced by DSS (HY-116282C). JAK2/STAT3-IN-2 can be used for the research of ulcerative colitis .
    JAK2/STAT3-IN-2

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