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Art. -Nr.: HY-187084

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Propionylthiocholine iodide

Propionylthiocholine iodide serves as a substrate for detecting the activities of acetylcholinesterase and pseudocholinesterase. Propionylthiocholine iodide acts as a substrate for intestinal epithelial cell-derived acetylcholinesterase and is resistant to hydrolysis by this enzyme.

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CAS. Nr.: 1866-73-5
Formel: C₈H₁₈INOS
Molecular Weight:303.20

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Please store the product under the recommended conditions in the Certificate of Analysis.

Propionylthiocholine iodide Chemical Structure

CAS. Nr.: 1866-73-5

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Biologische Aktivität

Beschreibung

Alle Cholinesterase (ChE) Isoform-spezifische Produkte anzeigen :

AChE
BChE

In Vitro

Propionylthiocholine iodide (37°C) exhibits pseudocholinesterase activity of 3261 U/l and acetylcholinesterase activity of 3928 U/l in human whole blood, yielding an acetylcholinesterase-to-pseudocholinesterase ratio of 1.20^[1].
Propionylthiocholine (1 mM) iodide is a poor substrate for the predominantly AChE activity present in Caco-2 human intestinal epithelial cells, with significantly lower hydrolytic activity observed compared to acetylthiocholine^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS. Nr. 1866-73-5
Molecular Weight 303.20
Formel C₈H₁₈INOS
SMILES

[I-].O=C(SCC[N+](C)(C)C)CC
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Handling Instructions (2659 KB)

Verweise

[1]. Ryhänen RJ, et al. Pseudocholinesterase activity in some human body fluids. General pharmacology. 1983;14(4):459-60.

[2]. Plageman LR, et al. Characterization of acetylcholinesterase in Caco-2 cells. Experimental biology and medicine (Maywood, N.J.). 2002 Jul;227(7):480-6.

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

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How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Propionylthiocholine iodide

Alle Cholinesterase (ChE) Isoform-spezifische Produkte anzeigen

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Propionylthiocholine iodide Related Classifications

HY-187084 Related Classifications