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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
14 Results for "
DLL1
" in MedChemExpress (MCE) Product Catalog:
Products (14)
14 Results for "DLL1" in MCE Product Catalog:
Cat. No.: HY-P990077
CAS No.: 1036730-42-3
Synonyms: CT-011; MDV9300
Target:
Research Areas:
Cat. No.: HY-RS03808
Target:
Research Areas:
DLL1 Human Pre-designed siRNA Set A contains three designed siRNAs for DLL1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS16910
Target:
Research Areas:
Dll1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Dll1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P990253
Research Areas:
Cat. No.: HY-RS23352
Target:
Research Areas:
Dll1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Dll1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P7841
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: DLL1; Delta-Like Ligand 1; Delta Like Canonical Notch Ligand 1; Delta-Like Protein; Drosophila Delta Homolog 1; DELTA1; Delta-Like Protein 1; NEDBAS; H-Delta-1; Delta1; Epididymis Secretory Sperm Binding Protein; Delta; Delta (Drosophila)-Like 1; DL1; Del
Species:
Human
Source:
HEK293
Cat. No.: HY-P705504
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: DLL1; Delta-Like Ligand 1; Delta Like Canonical Notch Ligand 1; Delta-Like Protein; Drosophila Delta Homolog 1; DELTA1; Delta-Like Protein 1; NEDBAS; H-Delta-1; Delta1; Epididymis Secretory Sperm Binding Protein; Delta; Delta (Drosophila)-Like 1; DL1; Del
Species:
Human
Source:
HEK293
Cat. No.: HY-P705141
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: DLL1; Delta-Like Ligand 1; Delta Like Canonical Notch Ligand 1; Delta-Like Protein; Drosophila Delta Homolog 1; DELTA1; Delta-Like Protein 1; NEDBAS; H-Delta-1; Delta1; Epididymis Secretory Sperm Binding Protein; Delta; Delta (Drosophila)-Like 1; DL1; Del
Species:
Human
Source:
HEK293
Cat. No.: HY-P72970
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: DLL1; Delta-Like Ligand 1; Delta Like Canonical Notch Ligand 1; Delta-Like Protein; Drosophila Delta Homolog 1; DELTA1; Delta-Like Protein 1; NEDBAS; H-Delta-1; Delta1; Epididymis Secretory Sperm Binding Protein; Delta; Delta (Drosophila)-Like 1; DL1; Del
Species:
Mouse
Source:
HEK293
Cat. No.: HY-P75295
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: DLL1; Delta-Like Ligand 1; Delta Like Canonical Notch Ligand 1; Delta-Like Protein; Drosophila Delta Homolog 1; DELTA1; Delta-Like Protein 1; NEDBAS; H-Delta-1; Delta1; Epididymis Secretory Sperm Binding Protein; Delta; Delta (Drosophila)-Like 1; DL1; Del
Species:
Rat
Source:
HEK293
Cat. No.: HY-P72970A
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: DLL1; Delta-Like Ligand 1; Delta Like Canonical Notch Ligand 1; Delta-Like Protein; Drosophila Delta Homolog 1; DELTA1; Delta-Like Protein 1; NEDBAS; H-Delta-1; Delta1; Epididymis Secretory Sperm Binding Protein; Delta; Delta (Drosophila)-Like 1; DL1; Del
Species:
Mouse
Source:
HEK293
Cat. No.: HY-P72971
Purity: ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: DLL1; Delta-Like Ligand 1; Delta Like Canonical Notch Ligand 1; Delta-Like Protein; Drosophila Delta Homolog 1; DELTA1; Delta-Like Protein 1; NEDBAS; H-Delta-1; Delta1; Epididymis Secretory Sperm Binding Protein; Delta; Delta (Drosophila)-Like 1; DL1; Del
Species:
Rat
Source:
HEK293
Cat. No.: HY-182008
CAS No.: 3068938-30-4
Target:
Molecular Glues E1/E2/E3 Enzyme Apoptosis Notch PARP Caspase Bcl-2 Family Ligands for E3 Ligase
Research Areas:
NEURL1B-IN-1 is a molecular glue-like NEURL1B degrader with a Kd value of 46.2 nM. NEURL1B-IN-1 binds to Arg422 within the NHR2 domain of NEURL1B, triggers its autoubiquitination and proteasomal degradation, disrupts its interaction with DLL1, and attenuates the Notch signaling pathway. NEURL1B-IN-1 induces cell cycle arrest and apoptosis, and inhibits migration of hepatocellular carcinoma cells. NEURL1B-IN-1 is applicable to research related to hepatocellular carcinoma [1].
Cat. No.: HY-187731
CAS No.: 685141-23-5
BXL0124 is an orally effective CD44 inhibitor and Notch signaling pathway inhibitor. BXL0124 has a vitamin D receptor-dependent mechanism and can downregulate the expression of CD44, Notch1/2/3, HES1, OCT4, LAMA5, JAG1, JAG2, NF-κB and DLL1. BXL0124 inhibits c-Myc expression and the levels of phosphorylated ERK, AKT, ErbB2, reduces the level of activated Notch1 receptor and its nuclear localization, decreases the mRNA and protein levels of Jagged-1 and Jagged-2, and inhibits the STAT3 signaling pathway by reducing the formation of the CD44-STAT3-JAK2 complex, while also inhibiting the transcriptional activity of the CD44 promoter in a p53-dependent manner. BXL0124 can induce myoepithelial differentiation and inhibit the self-renewal of cancer stem cell-like cells, cancer cell proliferation, invasion, and growth. BXL0124 can be used in research related to triple-negative breast cancer, basal-like breast cancer, ErbB2-overexpressing mammary tumorigenesis, and breast cancer [1] .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
