18 Results for "

DR4

" in MedChemExpress (MCE) Product Catalog:
Products (18)

18 Results for "DR4" in MCE Product Catalog:

  • Targets Recommended:
57
57 Cited Publications
Cat. No.: HY-17409
CAS No.: 1400-61-9
Nystatin is an orally active polyene antifungal antibiotic effective against yeast and mycoplasma. Nystatin increases the permeability of plasma membranes to small monovalent ions, including chloridion . Nystatin is a cholesterol-sequestering agent , partially prevents Oxaliplatin-induced lipid raft aggregation, DR4 and DR5 clustering, and thereby reduces apoptosis .
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-P99934
CAS No.: 1820660-69-2
Synonyms: ABBV-621

Research Areas:  

Cancer

Eftozanermin alfa (ABBV-621) is a tumor necrosis factor-related apoptosis-inducing ligand receptor (TRAIL-R) agonist. Eftozanermin alfa is a fusion protein consisting of a mutant immunoglobulin G1-Fc linked to 2 single-chain trimers of TRAIL. Eftozanermin alfa induces apoptosis in tumor cells by activation of death receptors (DR4 receptor and DR5 receptor) with Kds of 780 nM and 635 nM. Eftozanermin alfa can be used for the research of multiple solid and heme malignancies .
loading...
    loading...
Cat. No.: HY-P990715
CAS No.: 2539847-03-3
Synonyms: INBRX-109

Target:  

TNF Receptor

Research Areas:  

Cancer

Ozekibart (INBRX-109) is a DR5 agonist and antitumor agent with a human DR5 IC50 of 0.17 nmol/L and human DR5 Ka of 0.11 nmol/L. Ozekibart can be used for the research of unresectable/metastatic chondrosarcoma .
loading...
    loading...
Cat. No.: HY-157269
CAS No.: 1069110-72-0
Target:  

Hapten

Research Areas:  

Inflammation/Immunology

J10-1 is a hapten small molecule. J10-1 accelerates peptide exchange in MHC class II molecules in an HLA-DM-independent manner, and its effect is not affected by the polymorphism of the P1 pocket of MHC class II molecules. J10-1 enhances the processes of peptide dissociation, peptide binding and peptide association of MHC class II molecules on the surface of B cells. J10-1 can be used for research on immunoregulation .
loading...
    loading...
Cat. No.: HY-120794
CAS No.: 182134-00-5
Target:  

TNF Receptor

Research Areas:  

Inflammation/Immunology

SC 67655 is a potent and stable pentapeptide MHC class II haplotype DR4 (DR4 Dw4 or DRB 1"0401) ligand with an IC50 of 50 nM. SC 67655 can be used for the study of autoimmune diseases .
loading...
    loading...
Cat. No.: HY-P3639
CAS No.: 320341-56-8
Target:  

TNF Receptor

Research Areas:  

Others

SYLQDSVPDSFQD, anchor-modified for high-affinity binding to DR4, is a DR4-restricted MHC class II peptide Tyrosinase .
loading...
    loading...
Cat. No.: HY-P1901
CAS No.: 872036-64-1
Target:  

Insulin Receptor

Research Areas:  

Metabolic Disease

Insulin alpha-chain (1-13) is a human leucocyte antigen (HLA)-DR4-restricted epitope comprising the first 13 amino acids of the insulin A-chain .
loading...
    loading...
Cat. No.: HY-P78529
Purity:  ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: DR4; CD261; TNFRSF10A; TRAIL-R; APO2; TRAIL R1; MGC9365
Species:  
Source:  
loading...
    loading...
Cat. No.: HY-P78219
Purity:  ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: DR4; CD261; TNFRSF10A; TRAIL-R; APO2; TRAIL R1; MGC9365
Species:  
Source:  
loading...
    loading...
Cat. No.: HY-P74500
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: Tumor necrosis factor receptor superfamily member 10A; TRAIL-R1; CD261; APO2; DR4
Species:  
Source:  
loading...
    loading...
Cat. No.: HY-P87245
Synonyms: DR 4 antibody

Host:  

Rabbit

Application:  

WB, IHC-P, FC

Reactivity:  

Human

loading...
    loading...
Cat. No.: HY-P74501
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: Tumor necrosis factor receptor superfamily member 10A; TRAIL-R1; CD261; APO2; DR4
Species:  
Source:  
loading...
    loading...
Cat. No.: HY-181955
MS1129 is a DNMT degrader that induces proteasomal degradation of DNMT1, DNMT3A and DNMT3B proteins. MS1129 upregulates TRAIL, DR4 and DR5 proteins, downregulates the decoy receptor DcR2, and activates TRAIL-dependent apoptosis via the HIF-1/2 and Caspase-10 pathways. MS1129 is applicable to the research of VHL-deficient clear cell renal cell carcinoma .
loading...
    loading...
Cat. No.: HY-P72440
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Tumor necrosis factor receptor superfamily member 10A; TRAIL-R1; CD261; TNFRSF10A; APO2; DR4
Species:  
Source:  
loading...
    loading...
Cat. No.: HY-RS06213
Research Areas:  

Others

HLA-DRB4 Human Pre-designed siRNA Set A contains three designed siRNAs for HLA-DRB4 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

loading...
    loading...
Cat. No.: HY-RS14795
Research Areas:  

Others

TNFRSF10A Human Pre-designed siRNA Set A contains three designed siRNAs for TNFRSF10A gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

loading...
    loading...
Cat. No.: HY-P87404A
Synonyms: CD261, APO2, DR4, TRAILR1, TNFRSF10A, Tumor necrosis factor receptor superfamily member 10A, Death receptor 4, TNF-related apoptosis-inducing ligand receptor 1, TRAIL receptor 1, TRAIL-R1

Host:  

Rabbit

Application:  

WB, ICC/IF, FC

Reactivity:  

Human

loading...
    loading...
Cat. No.: HY-P87404

Host:  

Rabbit

Application:  

WB, ICC/IF, FC

Reactivity:  

Human

loading...
    loading...
  • 1