Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
15 Results for "
Ezetimibe
" in MedChemExpress (MCE) Product Catalog:
Products (15)
15 Results for "Ezetimibe" in MCE Product Catalog:
16
Target:
Forschungsgebiete:
Ezetimibe (SCH 58235) is a potent cholesterol absorption inhibitor. Ezetimibe is a Niemann-Pick C1-like1 (NPC1L1) inhibitor, and is a potent Nrf2 activator.
2
2 Cited Publications
Synonyms: Ezetimibe glucuronide; Ezetimibe β-D-glucuronide
Target:
Forschungsgebiete:
Ezetimibe phenoxy glucuronide (Ezetimibe glucuronide) is the active metabolite of Ezetimibe. Antihyperlipoproteinemic activity . Ezetimibe is a potent cholesterol absorption inhibitor .
Synonyms: EZM-K
Target:
Forschungsgebiete:
Cardiovascular Disease Metabolic Disease Inflammation/Immunology Cancer
Ezetimibe ketone is an orall active Nrf2 activator and ROS inhibitor. Ezetimibe ketone attenuates H2O2-induced reactive oxygen species production and reduces H2O2-induced apoptosis in renal tubular epithelial cells. Ezetimibe ketone suppresses renal tubular injury and inflammation .
Art. -Nr.: HY-136059
CAS. Nr.: 302781-98-2
Target:
Forschungsgebiete:
Desfluoro-ezetimibe is a desfluoro impurity of Ezetimibe. Ezetimibe is a potent, metabolically stable cholesterol absorption inhibitor. Ezetimibe is a Niemann-Pick C1-like1 (NPC1L1) inhibitor, and is a potent Nrf2 activator .
Art. -Nr.: HY-17376R
CAS. Nr.: 163222-33-1
Synonyms: SCH 58235 (Standard)
Target:
Forschungsgebiete:
Ezetimibe (Standard) is the analytical standard of Ezetimibe. This product is intended for research and analytical applications. Ezetimibe (SCH 58235) is a potent cholesterol absorption inhibitor. Ezetimibe is a Niemann-Pick C1-like1 (NPC1L1) inhibitor, and is a potent Nrf2 activator.
Art. -Nr.: HY-17376S
CAS. Nr.: 1093659-90-5
Synonyms: SCH 58235-d4
Art. -Nr.: HY-17376S1
CAS. Nr.: 1093659-89-2
Synonyms: SCH 58235-d4-1
Art. -Nr.: HY-135391S
CAS. Nr.: 1426174-41-5
Synonyms: Ezetimibe glucuronide-d4; Ezetimibe β-D-glucuronide-d4
Art. -Nr.: HY-135388
CAS. Nr.: 1376614-99-1
Synonyms: ent-SCH 58235
Target:
Forschungsgebiete:
ent-Ezetimibe (ent-SCH 58235) is the RRS-enantiomer of Ezetimibe. Ezetimibe is a potent cholesterol absorption inhibitor. Ezetimibe is a Niemann-Pick C1-like1 (NPC1L1) inhibitor, and is a potent Nrf2 activator .
Art. -Nr.: HY-143807S
Art. -Nr.: HY-Z3151
CAS. Nr.: 1798008-25-9
Target:
Forschungsgebiete:
3'-(2-Fluorophenyl) ezetimibe is an isomer of the cholesterol transport inhibitor Ezetimibe (HY-17376).
Art. -Nr.: HY-135245
CAS. Nr.: 536709-33-8
Synonyms: SCH 488128; Ezetimibe hydroxy β-D-Glucuronide
Target:
Forschungsgebiete:
Ezetimibe hydroxy glucuronide (SCH 488128) is a trace metabolite detected in dog and human plasma samples after oral administration of Ezetimibe (HY-17376) .
Art. -Nr.: HY-133114R
CAS. Nr.: 191330-56-0
Synonyms: EZM-K (Standard)
Target:
Forschungsgebiete:
Cardiovascular Disease Metabolic Disease Inflammation/Immunology Cancer
Ezetimibe ketone (Standard) is the analytical standard of Ezetimibe ketone (HY-133114). This product is intended for research and analytical applications. Ezetimibe ketone is an orall active Nrf2 activator and ROS inhibitor. Ezetimibe ketone attenuates H2O2-induced reactive oxygen species production and reduces H2O2-induced apoptosis in renal tubular epithelial cells. Ezetimibe ketone suppresses renal tubular injury and inflammation .
Art. -Nr.: HY-17376S3
CAS. Nr.: 438624-68-1
Synonyms: SCH 58235-13C6
Art. -Nr.: HY-18778C
CAS. Nr.: 866399-89-5
Synonyms: TA-8995 hemicalcium; DEZ-001 hemicalcium; AMG-899 hemicalcium
Forschungsgebiete:
Obicetrapib hemicalcium (TA-8995 hemicalcium) is an orally active cholesteryl ester transfer protein (CETP) inhibitor. Obicetrapib hemicalcium shifts the plasma lipoprotein profile toward more HDL-C particles, reduces circulating PCSK9 levels, increases hepatic LDLR expression and LDLR mRNA levels, and promotes hepatic clearance of VLDL remnants. Obicetrapib hemicalcium increases the number of large HDL particles, reduces the number and area of atherosclerotic lesions and alleviates lesion severity, increases the proportion of unaffected arterial segments, improves lesion stability, and promotes regression of aortic root lesions. Obicetrapib hemicalcium also exerts a synergistic effect with Ezetimibe (HY-17376) to reduce non-HDL-C levels and improve atherosclerosis. Obicetrapib hemicalcium can be used in studies related to atherosclerosis and dyslipidemia .
- 1
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
