Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
62 Results for "
FBP
" in MedChemExpress (MCE) Product Catalog:
Products (62)
62 Results for "FBP" in MCE Product Catalog:
Cat. No.: HY-182266
Research Areas:
FBP is a mitochondria-targeted, selective anticancer agent. FBP induces oxidative stress and mitochondrial dysfunction, leading to Apoptosis. FBP generates ROS and causes double-strand DNA breaks in cancer cells. FBP exhibits cytotoxic efficacy against cancer cells, with cervical cancer cells being the most sensitive. FBP can be used for the research of cervical cancer, lung cancer, melanoma and breast cancer .
7
7 Cited Publications
Cat. No.: HY-16307
CAS No.: 261365-11-1
Target:
Research Areas:
MB05032 is a fructose-1,6-bisphosphatase (FBP1/FBPase) inhibitor with an IC50 value of 16 nM. MB05032 blocks FBP1-mediated glycolysis inhibition in NK cells, restores NK cell glucose uptake, lactate production, degranulation, perforin production, and cytotoxicity against gastric cancer cells. MB05032 elevates ATP/ADP ratios, increases glucose utilization, and enhances insulin secretion in pancreatic β-cells. MB05032 increases neutrophil adhesion, phagocytosis, and mRNA abundance of HKII, ITGA9, CD36 in subclinically hypocalcemic dairy cows. MB05032 inhibits gluconeogenesis in hepatocytes, acts as the active metabolite of prodrug Managlinat dialanetil (MB06322) (HY-14955). MB05032 can be used for the research of gastric cancer, type 2 diabetes, subclinical hypocalcemia, and insulin resistance .
2
2 Cited Publications
Cat. No.: HY-P70275
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: FBP1; Liver FBPase; Prev. FBP; Growth-Inhibiting Protein 17; Fructose-1,6-Bisphosphatase 1; Fructose-Bisphosphatase; D-Fructose-1,6-Bisphosphate 1-Phosphohydrolase 1; Fructose-Bisphosphatase 1; FBPase 1
Species:
Human
Source:
HEK293
Cat. No.: HY-16309
CAS No.: 882757-24-6
Target:
Research Areas:
MB-07803 is an orally active second-generation prodrug inhibitor of fructose-1,6-bisphosphatase (FBP1). MB-07803 directly inhibits the rate-limiting enzyme in gluconeogenesis. MB-07803 regulates blood glucose and is used in studies of type 2 diabetes .
Cat. No.: HY-RS17537
Target:
Research Areas:
Fbp1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Fbp1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS04779
Target:
Research Areas:
FBP1 Human Pre-designed siRNA Set A contains three designed siRNAs for FBP1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS04780
Target:
Research Areas:
FBP2 Human Pre-designed siRNA Set A contains three designed siRNAs for FBP2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS17637
Target:
Research Areas:
Fbp2 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Fbp2 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P10293
CAS No.: 372135-74-5
Target:
Research Areas:
Cat. No.: HY-RS11523
Target:
Research Areas:
RAB14 Human Pre-designed siRNA Set A contains three designed siRNAs for RAB14 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS05141
Target:
Research Areas:
FUBP1 Human Pre-designed siRNA Set A contains three designed siRNAs for FUBP1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS05029
Target:
Research Areas:
FOLR1 Human Pre-designed siRNA Set A contains three designed siRNAs for FOLR1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS17978
Target:
Research Areas:
Fubp1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Fubp1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS05030
Target:
Research Areas:
FOLR2 Human Pre-designed siRNA Set A contains three designed siRNAs for FOLR2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-155726
CAS No.: 444792-16-9
Cy-FBP/SBPase-IN-1 (compound S5) is a Cy-FBP/SBPase inhibitor, which is an important regulatory enzyme in cyanobacterial photosynthesis. Thus Cy-FBP/SBPase-IN-1 inhibits Calvin cycle and photosystem, and decreases photosynthetic efficiency in cyanobacterial photosynthesis. Cy-FBP/SBPase-IN-1 potently inhibits the growth of cyanobacteria, as well as Synechocystis sp.PCC6803. Cy-FBP/SBPase-IN-1 shows safety profile in human-derived cells and zebrafish models .
Cat. No.: HY-RS23994
Target:
Research Areas:
Fbp1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Fbp1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS24097
Target:
Research Areas:
Fbp2 Rat Pre-designed siRNA Set A contains three designed siRNAs for Fbp2 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P78870
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: FOLR2; FOLR2 Protein; Folate Receptor Beta; BETA-HFR; Folate Receptor, Fetal/Placental; FBP/PL-1; Placental Folate-Binding Protein; FR-BETA; Folate Receptor 2 (Fetal); FR-Beta; FBP; FRbeta; Folate-Binding Protein, Fetal/Placental; FR-P3; Folate Receptor A
Species:
Human
Source:
HEK293
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
