27 Results for "

Glutamate decarboxylase

" in MedChemExpress (MCE) Product Catalog:
Products (27)

27 Results for "Glutamate decarboxylase" in MCE Product Catalog:

Cat. No.: HY-E70570
CAS No.: 9024-58-2
Target:  

GABA Receptor

Research Areas:  

Metabolic Disease

Glutamate decarboxylase is an enzyme that catalyzes the decarboxylation of glutamate to gamma-aminobutyric acid (GABA) and carbon dioxide (CO2). Many gut microbes can metabolize glutamate via their Glutamate decarboxylase in a pyridoxal-5′-phosphate (PLP) dependent manner .
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2
2 Cited Publications
Cat. No.: HY-W016814
CAS No.: 585-84-2
Synonyms: cis-Aconitic acid
(Z)-Aconitic acid is an orally active glutamate decarboxylase inhibitor. (Z)-Aconitic acid reduces IκB-α phosphorylation. (Z)-Aconitic acid inhibits Antigen-induced arthritis and Monosodium urate (HY-B2130A)-induced gout .
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1
1 Cited Publications
Cat. No.: HY-Y0367
CAS No.: 110-16-7
Maleic Acid is a Glutamate Decarboxylase (GAD) inhibitor of E. coli and L. monocytogenes.
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1
1 Cited Publications
Cat. No.: HY-W012906
CAS No.: 16338-48-0
Synonyms: L-2-Allylglycine
L-Allylglycine (L-2-Allylglycine) is an amino acid derivative. L-Allylglycine is an inhibitor for glutamate decarboxylase (GAD) that reduces the GABA biosynthesis in the brain. L-Allylglycine exhibits convulsant activity .
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1 Cited Publications
Cat. No.: HY-W041489
CAS No.: 99-32-1
Chelidonic acid is a component of Chelidonium majus L., used as an antimicrobial. Chelidonic acid also shows anti-inflammatory activity. Chelidonic acid has potential to inhibit IL-6 production by blocking NF-κB and caspase-1 . Chelidonic acid is a glutamate decarboxylase inhibitor, with a Ki of 1.2 μM .
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1 Cited Publications
Cat. No.: HY-W015595
CAS No.: 195316-72-4
Synonyms: L-2-Allylglycine hydrochloride
L-Allylglycine (L-2-Allylglycine) hydrochloride is an amino acid derivative. L-Allylglycine hydrochloride is an inhibitor for glutamate decarboxylase (GAD) that reduces the GABA biosynthesis in the brain. L-Allylglycine hydrochloride exhibits convulsant activity .
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1 Cited Publications
Cat. No.: HY-P75178
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: GAD2; Glutamate decarboxylase 65 KDa Isoform; Glutamate decarboxylase 2; GAD-65; GAD65; Glutamate decarboxylase 2 (Pancreatic Islets And Brain, 65kD); 65 KDa Glutamic Acid decarboxylase; Glutamate decarboxylase-2 (Pancreas); Glutamate decarboxylase 2 (Pan
Species:  
Mouse
Source:  
Sf9 insect cells
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Cat. No.: HY-W016349
CAS No.: 138-60-3
Research Areas:  

Others

Chelidamic acid is a heterocyclic organic acid with a pyran skeleton. Chelidamic acid has good coordination ability with noble metal ions. Chelidamic acid is also one of the most potent inhibitors of glutamate decarboxylase, with a Ki of 33 μM.
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Cat. No.: HY-W023493
CAS No.: 7685-44-1
Synonyms: 2-Aminopent-4-enoic acid
Research Areas:  

Neurological Disease

DL-Allylglycine (2-Aminopent-4-enoic acid) is a glutamate decarboxylase (GAD) inhibitor. DL-Allylglycine significantly increases mouse brain ornithine decarboxylase (ODC) activity and decreases S-adenosyl-L-methionine decarboxylase (SAM-DC) activity. DL-Allylglycine causes a marked decrease in brain GABA concentration. DL-Allylglycine has convulsant activity that can be used in studies to induce epileptic seizures .
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Cat. No.: HY-N15001
CAS No.: 59556-18-2
Gabaculine is an amino acid neurotoxin and blood-brain barrier-permeable GABA transaminase inhibitor, with an IC50 of 1 μM in beef and Pseudomonas ovalis. Gabaculine elevates endogenous synaptic and brain GABA levels and enhances GABA activity. Gabaculine induces sedation, hypothermia, loss of righting reflex, and prevents convulsions in mice. Gabaculine is applicable to research related to neurological disorders .
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Cat. No.: HY-Y0367S
CAS No.: 24461-33-4
Synonyms: Maleic-2,3-d2 acid
Maleic Acid-d2 is the deuterium labeled Maleic Acid . Maleic Acid is a Glutamate Decarboxylase (GAD) inhibitor of E. coli and L. monocytogenes .
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Cat. No.: HY-W016814R
CAS No.: 585-84-2
Synonyms: cis-Aconitic acid (Standard)
(Z)-Aconitic acid (Standard) is the analytical standard of (Z)-Aconitic acid. This product is intended for research and analytical applications. (Z)-Aconitic acid is a glutamate decarboxylase inhibitor. (Z)-Aconitic acid reduces IκB-α phosphorylation. (Z)-Aconitic acid inhibits Antigen-induced arthritis and Monosodium urate (HY-B2130A)-induced gout .
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Cat. No.: HY-Y0367R
CAS No.: 110-16-7
Maleic Acid (Standard) is the analytical standard of Maleic Acid. This product is intended for research and analytical applications. Maleic Acid is a Glutamate Decarboxylase (GAD) inhibitor of E. coli and L. monocytogenes. IC50 & Target: GAD . In Vitro: The MICs of WT 10403S for the acids (e.g., Maleic Acid) are 34 mM, 25 mM, 31 mM and 30 mM which correspond to pH values prior to growth of 4.84, 5.14, 5.32 and 5.02 respectively. Of all compounds tested, Maleic Acid is the least inhibitory despite acting at a lower pH (4.84). The most acid resistant (10403S) and the weakest (EGD-e) strain are challenged with 8.6 mM and 4.3 mM of each organic acid at pH 3 and 3.3 respectively. On both strains, Maleic Acid is the most bactericidal .
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Cat. No.: HY-15121A
CAS No.: 34271-54-0
Synonyms: DL-Glutamic acid γ-ethyl amide; Nγ-Ethyl-DL-glutamine
Target:  

Bacterial

Research Areas:  

Infection

DL-Theanine (DL-Glutamic acid γ-ethyl amide) is an antimetabolite of L-glutamic acid, and exhibits antibacterial activity against Staphylococcus aureus and Escherichia coli. DL-Theanine shows no significant inhibitory activity against bacterial glutamate decarboxylase. DL-Theanine can be used in studies related to bacterial infections .
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Cat. No.: HY-P5305A
Target:  

GABA Receptor

Research Areas:  

Metabolic Disease

GAD65(247-266) epitope TFA is the T cell epitopes of islet antigens,binding to I-A g7 (type I diabetes-associated molecule) competitively with poor affinity. GAD65 refers to Glutamic Acid Decarboxylase 65,involved in the conversion of glutamate to gamma-aminobutyric acid (GABA) .
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Cat. No.: HY-W041489R
CAS No.: 99-32-1
Chelidonic acid (Standard) is the analytical standard of Chelidonic acid. This product is intended for research and analytical applications. Chelidonic acid is a component of Chelidonium majus L., used as an antimicrobial. Chelidonic acid also shows anti-inflammatory activity. Chelidonic acid has potential to inhibit IL-6 production by blocking NF-κB and caspase-1 . Chelidonic acid is a glutamate decarboxylase inhibitor, with a Ki of 1.2 μM .
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Cat. No.: HY-P85817
Synonyms: GLUL; GLNS; Glutamine synthetase; GS; Glutamate decarboxylase; Glutamate--ammonia ligase

Host:  

Mouse

Application:  

WB, ICC/IF, ELISA, IHC-P

Reactivity:  

Human, Mouse, Rat

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Cat. No.: HY-P86524
Synonyms: GLUL; GLNS; Glutamine synthetase; GS; Glutamate decarboxylase; Glutamate--ammonia ligase

Host:  

Rabbit

Application:  

WB, IHC-P, ICC/IF, IP, ELISA

Reactivity:  

Human, Mouse, Rat

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Cat. No.: HY-P70294
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: GLUL; Proliferation-Inducing Protein 43; Prev. GLNS; Glutamate decarboxylase; Glutamine Synthetase; Glutamine Synthase; Palmitoyltransferase GLUL; DEE116; GS; PIG43; Glutamate-Ammonia Ligase (Glutamine Synthase); PIG59; Cell Proliferation-Inducing Protein
Species:  
Human
Source:  
E. coli
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Cat. No.: HY-P75179
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: GAD2; Glutamate decarboxylase 65 KDa Isoform; Glutamate decarboxylase 2; GAD-65; GAD65; Glutamate decarboxylase 2 (Pancreatic Islets And Brain, 65kD); 65 KDa Glutamic Acid decarboxylase; Glutamate decarboxylase-2 (Pancreas); Glutamate decarboxylase 2 (Pancreatic Islets And Brain, 65kDa); Glutamate decarboxylase
Species:  
Human
Source:  
Sf9 insect cells
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