585-84-2
585-84-2
Chemical Structure
(Z)-Aconitic acid
Synonym(s): cis-Aconitic acid
- CAS No.: 585-84-2
- Formula:C6H6O6
- Molecular Weight:174.11
SMILES: O=C(O)/C([H])=C(C(O)=O)/CC(O)=O.
Biological Activity: (Z)-Aconitic acid is an orally active glutamate decarboxylase inhibitor. (Z)-Aconitic acid reduces IκB-α phosphorylation. (Z)-Aconitic acid inhibits Antigen-induced arthritis and Monosodium urate (HY-B2130A)-induced gout[1][2].
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(Z)-Aconitic acid | 99.28% | (Z)-Aconitic acid is an orally active glutamate decarboxylase inhibitor. (Z)-Aconitic acid reduces IκB-α phosphorylation. (Z)-Aconitic acid inhibits Antigen-induced arthritis and Monosodium urate (HY-B2130A)-induced gout. | ||||||||||||||||||||
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(Z)-Aconitic acid (Standard) | 99.13% | (Z)-Aconitic acid (Standard) is the analytical standard of (Z)-Aconitic acid. This product is intended for research and analytical applications. (Z)-Aconitic acid is a glutamate decarboxylase inhibitor. (Z)-Aconitic acid reduces IκB-α phosphorylation. (Z)-Aconitic acid inhibits Antigen-induced arthritis and Monosodium urate (HY-B2130A)-induced gout. | ||||||||||||||||||||
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References
- [1]. de Oliveira DP, et al. cis-Aconitic Acid, a Constituent of Echinodorus grandiflorus Leaves, Inhibits Antigen-Induced Arthritis and Gout in Mice. Planta Med. 2022 Oct;88(13):1123-1131. [Content Brief]
- [2]. Endo A, et al. Cis-and tram-aconitic acids as inhibitors of glutamate decarboxylase. Hoppe-Seyler’s Z. Physiol, 1977: 1365-1368.
