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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
15 Results for "
IFNB1
" in MedChemExpress (MCE) Product Catalog:
Products (15)
15 Results for "IFNB1" in MCE Product Catalog:
12
12 Publications Verification
Research Areas:
STING-IN-2 (C-170) is a potent and covalent STING inhibitor. STING-IN-2 efficiently inhibits both mouse STING (mmSTING) and human STING (hsSTING). STING-IN-2 can be used for autoinflammatory disease research [1].
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Cat. No.: HY-174664
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Human IFNB1 mRNA encodes the human interferon beta 1 (IFNB1) protein, a cytokine that belongs to the interferon family. IFNB1 belongs to the type I class of interferons, which are important for defense against viral infections. In addition, type I interferons are involved in cell differentiation and anti-tumor defenses.
Cat. No.: HY-RS06585
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IFNB1 Human Pre-designed siRNA Set A contains three designed siRNAs for IFNB1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS17301
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Ifnb1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Ifnb1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS23756
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Ifnb1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Ifnb1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-178951
CAS No.: 3069635-58-8
Research Areas:
STING-IN-17 (compound 10a) is an orally active STING (human STING IC50 = 29 nM, mouse STING IC50 = 15 nM) inhibitor. STING-IN-17 can inhibit the phosphorylation of STING, TBK1 and IRF3. STING-IN-17 dose dependently inhibits the mRNA expression of IP10, IFNB1 and ISG56. STING-IN-17 can reduce ROS and inhibit the expression of cleaved-PARP/caspase-3. STING-IN-17 can improve kidney function. STING-IN-17 can be used for research on inflammatory conditions such as acute kidney injury [1].
Cat. No.: HY-P700090AF
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IFNB1; Type I Interferon
Cat. No.: HY-P73132Y
Purity: ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: Interferon beta; IFN-beta; IFNB1; IFB; IFNB
Species:
Source:
Cat. No.: HY-P73132
Purity: ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: Interferon beta; IFN-beta; IFNB1; IFB; IFNB
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Source:
Cat. No.: HY-147129
CAS No.: 2369750-66-1
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cGAS-IN-9 is a cyclic guanosine monophosphate-adenosine monophosphate synthase (cGAS) inhibitor, with IC50 values of 27.5 nM and 5.15 μM against human and murine cGAS, respectively. cGAS-IN-9 shows weak inhibitory activity against human soluble adenylate cyclase, with an IC50 of 26.4 μM. cGAS-IN-9 inhibits dsDNA-induced expression of IFNB1 and CXCL10, as well as activation of the NF-κB pathway, in human immune cells. cGAS-IN-9 can be used in research related to cGAS-dependent inflammatory diseases [1].
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
