22 Results for "

IL-7 receptor alpha

" in MedChemExpress (MCE) Product Catalog:
Products (22)

22 Results for "IL-7 receptor alpha" in MCE Product Catalog:

Cat. No.: HY-P990774
CAS No.: 2768386-15-6
Synonyms: ASP-7266; TRAB-1; UPB-101

Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology

Verekitug (ASP-7266; TRAB-1; UPB-101) is a human monoclonal antibody targeting the thymic stromal lymphopoietin receptor (TSLPR), with a mean half-life of approximately 20 days. At doses of Verekitug ≥100 mg, complete and sustained TSLPR-specific occupancy is achieved, and the antibody does not bind to IL-7Rα. By inhibiting TSLP-driven inflammatory responses, Verekitug blocks TSLP-induced cell proliferation and TARC expression, while reducing fractional exhaled NO levels, blood eosinophil counts, and levels of IL-5 and IgE. Verekitug significantly improves scores for nasal polyps, nasal congestion and olfactory dysfunction, with favorable safety and good tolerability; potential adverse reactions include headache, upper respiratory tract infection, sinusitis and nasopharyngitis. Verekitug is used in relevant studies on asthma, chronic rhinosinusitis with nasal polyps and chronic obstructive pulmonary disease .
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Cat. No.: HY-P990023
CAS No.: 2622254-57-1
Synonyms: ADX-914
Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology

Bempikibart (ADX-914) is a fully human IgG1-κ monoclonal antibody targeting IL-7Rα. Bempikibart binds to the IL-7 receptor alpha and blocks IL-7 and TSLP signaling. Bempikibart reduces T cell populations while relatively preserving regulatory T cells. Bempikibart inhibits Th1, Th2, and Th17 immune pathways. Bempikibart can be used in research on alopecia areata and atopic dermatitis .
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Cat. No.: HY-P991720
CAS No.: 2985643-31-8

Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology

Tepilukimig is a bivalent humanized IgG1κ monoclonal antibody inhibitor targeting TSLP-IL7Rα and TSLP-CRLF2. Tepilukimig inhibits the binding of TSLP to its receptors (IL7Rα and CRLF2) on the cell surface, thereby completely interrupting the inflammatory signaling pathway driven by TSLP. Tepilukimig can be used for allergic and inflammatory diseases like atopic dermatitis and asthma research .
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Cat. No.: HY-P80593
Synonyms: IL7R; Interleukin-7 receptor subunit alpha; IL-7 receptor subunit alpha; IL-7R subunit alpha; IL-7R-alpha; IL-7RA; CDw127; CD antigen CD127

Host:  

Rabbit

Application:  

WB

Reactivity:  

Human

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Cat. No.: HY-P80593A
Synonyms: IL7R; Interleukin-7 receptor subunit alpha; IL-7 receptor subunit alpha; IL-7R subunit alpha; IL-7R-alpha; IL-7RA; CDw127; CD antigen CD127

Host:  

Rabbit

Application:  

WB

Reactivity:  

Human

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Cat. No.: HY-P72537
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL7R; Soluble Interleukin-7 receptor; Interleukin 7 receptor; IL-7 receptor Subunit alpha; CDw127; IL-7R Subunit alpha; Interleukin-7 receptor Subunit alpha; CD127 Antigen; IL-7Ralpha; IL-7R-alpha; IL7Ralpha; Interleukin 7 receptor alpha Chain; Lnc-IL7R;
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-P76436
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL7R; Soluble Interleukin-7 receptor; Interleukin 7 receptor; IL-7 receptor Subunit alpha; CDw127; IL-7R Subunit alpha; Interleukin-7 receptor Subunit alpha; CD127 Antigen; IL-7Ralpha; IL-7R-alpha; IL7Ralpha; Interleukin 7 receptor alpha Chain; Lnc-IL7R;
Species:  
Mouse
Source:  
HEK293
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Cat. No.: HY-P77011
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL7R; Soluble Interleukin-7 receptor; Interleukin 7 receptor; IL-7 receptor Subunit alpha; CDw127; IL-7R Subunit alpha; Interleukin-7 receptor Subunit alpha; CD127 Antigen; IL-7Ralpha; IL-7R-alpha; IL7Ralpha; Interleukin 7 receptor alpha Chain; Lnc-IL7R;
Species:  
Rat
Source:  
HEK293
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Cat. No.: HY-P77425
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL7R; Soluble Interleukin-7 receptor; Interleukin 7 receptor; IL-7 receptor Subunit alpha; CDw127; IL-7R Subunit alpha; Interleukin-7 receptor Subunit alpha; CD127 Antigen; IL-7Ralpha; IL-7R-alpha; IL7Ralpha; Interleukin 7 receptor alpha Chain; Lnc-IL7R;
Species:  
Cynomolgus
Source:  
HEK293
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Cat. No.: HY-P703696
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: IL7R; Soluble Interleukin-7 receptor; Interleukin 7 receptor; IL-7 receptor Subunit alpha; CDw127; IL-7R Subunit alpha; Interleukin-7 receptor Subunit alpha; CD127 Antigen; IL-7Ralpha; IL-7R-alpha; IL7Ralpha; Interleukin 7 receptor alpha Chain; Lnc-IL7R;
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-P72536
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL7R; Soluble Interleukin-7 receptor; Interleukin 7 receptor; IL-7 receptor Subunit alpha; CDw127; IL-7R Subunit alpha; Interleukin-7 receptor Subunit alpha; CD127 Antigen; IL-7Ralpha; IL-7R-alpha; IL7Ralpha; Interleukin 7 receptor alpha Chain; Lnc-IL7R;
Species:  
Mouse
Source:  
HEK293
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Cat. No.: HY-P77012
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL7R; Soluble Interleukin-7 receptor; Interleukin 7 receptor; IL-7 receptor Subunit alpha; CDw127; IL-7R Subunit alpha; Interleukin-7 receptor Subunit alpha; CD127 Antigen; IL-7Ralpha; IL-7R-alpha; IL7Ralpha; Interleukin 7 receptor alpha Chain; Lnc-IL7R;
Species:  
Rat
Source:  
HEK293
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Cat. No.: HY-P704720
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL7R; Soluble Interleukin-7 receptor; Interleukin 7 receptor; IL-7 receptor Subunit alpha; CDw127; IL-7R Subunit alpha; Interleukin-7 receptor Subunit alpha; CD127 Antigen; IL-7Ralpha; IL-7R-alpha; IL7Ralpha; Interleukin 7 receptor alpha Chain; Lnc-IL7R;
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-P704721
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL7R; Soluble Interleukin-7 receptor; Interleukin 7 receptor; IL-7 receptor Subunit alpha; CDw127; IL-7R Subunit alpha; Interleukin-7 receptor Subunit alpha; CD127 Antigen; IL-7Ralpha; IL-7R-alpha; IL7Ralpha; Interleukin 7 receptor alpha Chain; Lnc-IL7R;
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-P704722
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: IL7R; Soluble Interleukin-7 receptor; Interleukin 7 receptor; IL-7 receptor Subunit alpha; CDw127; IL-7R Subunit alpha; Interleukin-7 receptor Subunit alpha; CD127 Antigen; IL-7Ralpha; IL-7R-alpha; IL7Ralpha; Interleukin 7 receptor alpha Chain; Lnc-IL7R;
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-P7785
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL7R; Soluble Interleukin-7 receptor; Interleukin 7 receptor; IL-7 receptor Subunit alpha; CDw127; IL-7R Subunit alpha; Interleukin-7 receptor Subunit alpha; CD127 Antigen; IL-7Ralpha; IL-7R-alpha; IL7Ralpha; Interleukin 7 receptor alpha Chain; Lnc-IL7R;
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-P705229
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: IL7R; Soluble Interleukin-7 receptor; Interleukin 7 receptor; IL-7 receptor Subunit alpha; CDw127; IL-7R Subunit alpha; Interleukin-7 receptor Subunit alpha; CD127 Antigen; IL-7Ralpha; IL-7R-alpha; IL7Ralpha; Interleukin 7 receptor alpha Chain; Lnc-IL7R;
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-P76433
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL7R; Soluble Interleukin-7 receptor; Interleukin 7 receptor; IL-7 receptor Subunit alpha; CDw127; IL-7R Subunit alpha; Interleukin-7 receptor Subunit alpha; CD127 Antigen; IL-7Ralpha; IL-7R-alpha; IL7Ralpha; Interleukin 7 receptor alpha Chain; Lnc-IL7R;
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-P704719
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL7R; Soluble Interleukin-7 receptor; Interleukin 7 receptor; IL-7 receptor Subunit alpha; CDw127; IL-7R Subunit alpha; Interleukin-7 receptor Subunit alpha; CD127 Antigen; IL-7Ralpha; IL-7R-alpha; IL7Ralpha; Interleukin 7 receptor alpha Chain; Lnc-IL7R;
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-P704255
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: IL7R; Soluble Interleukin-7 receptor; Interleukin 7 receptor; IL-7 receptor Subunit alpha; CDw127; IL-7R Subunit alpha; Interleukin-7 receptor Subunit alpha; CD127 Antigen; IL-7Ralpha; IL-7R-alpha; IL7Ralpha; Interleukin 7 receptor alpha Chain; Lnc-IL7R; Interleukin-7 receptor; SIL-7R; IMD104; CD127; IL-7RA; IL7RA; ILRA
Species:  
Human
Source:  
HEK293
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