58 Results for "

IL7

" in MedChemExpress (MCE) Product Catalog:
Products (58)

58 Results for "IL7" in MCE Product Catalog:

4
4 Cited Publications
Cat. No.: HY-P7045
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: rHuIL-7; LP-1; pre-B cell factor
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2
2 Cited Publications
Cat. No.: HY-P73226
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: Interleukin 7; Lymphopoietin-1; PBGF
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1
1 Cited Publications
Cat. No.: HY-P99412
CAS No.: 2375835-91-7
Synonyms: OSE-127

Target:  

Interleukin Related

Research Areas:  

Cancer

Lusvertikimab (OSE-127) is a humanized IL7R monoclonal antibody. Lusvertikimab is not internalized by target cells and prevents IL7R heterodimerization and subsequent downstream signaling. Lusvertikimab has anti-leukemic efficacy and has the potential for B cell precursor acute lymphoblastic leukemia (BCP-ALL) research .
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1
1 Cited Publications
Cat. No.: HY-P990210

Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology

Anti-Mouse/Human IL-7 Antibody (M25) is an anti-mouse IL-7 IgG2b monoclonal antibody. Anti-Mouse/Human IL-7 Antibody (M25) alleviates inflammation by blocking IL-7 signaling and inhibiting innate lymphoid cells (ILC2s) activation. Anti-Mouse/Human IL-7 Antibody (M25) can reduce the number of B cell precursors. Anti-Mouse/Human IL-7 Antibody (M25) can be used for researches on inflammation conditions such as airway inflammation .
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1
1 Cited Publications
Cat. No.: HY-P990209
Anti-Mouse IL-7Rα/CD127 Antibody (A7R34) is a rat-derived IgG2a κ type antibody inhibitor, targeting to mouse IL-7Rα/CD127. Anti-Mouse IL-7Rα/CD127 Antibody (A7R34) blocks IL-7 signaling. Anti-Mouse IL-7Rα/CD127 Antibody (A7R34) can be used for the researches of cancer,infection, inflammation, immunology, cardiovascular and metabolic disease, such as abdominal aortic aneurysms, helicobacter felis-induced gastritis and diabetes .
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1
1 Cited Publications
Cat. No.: HY-P700217AF
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL-7; IL-7 interleukin-7; interleukin-7; Lymphopoietin -1; PBGF
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Cat. No.: HY-P99908
CAS No.: 2026634-47-7
Synonyms: NT-17

Target:  

Interleukin Related

Research Areas:  

Cancer

Efineptakin alfa (NT-17) is a long-acting recombinant human IL-7. Efineptakin alfa supports the proliferation and survival CD4 + and CD8 + cells in both human and mice. Efineptakin alfa can be used for glioblastoma research .
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Cat. No.: HY-P990774
CAS No.: 2768386-15-6
Synonyms: ASP-7266; TRAB-1; UPB-101

Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology

Verekitug (ASP-7266; TRAB-1; UPB-101) is a human monoclonal antibody targeting the thymic stromal lymphopoietin receptor (TSLPR), with a mean half-life of approximately 20 days. At doses of Verekitug ≥100 mg, complete and sustained TSLPR-specific occupancy is achieved, and the antibody does not bind to IL-7Rα. By inhibiting TSLP-driven inflammatory responses, Verekitug blocks TSLP-induced cell proliferation and TARC expression, while reducing fractional exhaled NO levels, blood eosinophil counts, and levels of IL-5 and IgE. Verekitug significantly improves scores for nasal polyps, nasal congestion and olfactory dysfunction, with favorable safety and good tolerability; potential adverse reactions include headache, upper respiratory tract infection, sinusitis and nasopharyngitis. Verekitug is used in relevant studies on asthma, chronic rhinosinusitis with nasal polyps and chronic obstructive pulmonary disease .
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Cat. No.: HY-P990023
CAS No.: 2622254-57-1
Synonyms: ADX-914

Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology

Bempikibart (ADX-914) is a fully human anti-IL-7Rα antibody that re-regulates adaptive immune function by blocking signaling mediated by both IL-7 and thymic stromal lymphopoietin (TSLP). Bempikibart can be used for the study of atopic dermatitis and alopecia areata .
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Cat. No.: HY-P991424

Research Areas:  

Inflammation/Immunology

GSK2618960 is a human monoclonal antibody (mAb) targeting IL-7Ra/CD127. GSK2618960 inhibits IL-7-induced STAT5 phosphorylation. GSK2618960 enhances CD4 T cell proliferation response and increases CD83, CD86, and CD209 expression in PBMCs. GSK2618960 can be used for the research of autoimmune and allergic inflammatory diseases. Recommended isotype control: Human IgG1 kappa, Isotype Control (HY-P99001) .
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Cat. No.: HY-P990911
CAS No.: 2893793-17-2
Synonyms: ZB-168

Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology

HY-P990911 is an IL7R-targeting IgG1λ2 type human antibody, the recommed isotype control is Human IgG1 lambda2, Isotype Control (HY-P990096) .
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Cat. No.: HY-RS06779
Research Areas:  

Others

IL7 Human Pre-designed siRNA Set A contains three designed siRNAs for IL7 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-174598
Target:  

mRNA

Research Areas:  

Inflammation/Immunology

Human IL7 mRNA encodes the human interleukin 7 (IL7) protein, a cytokine that is important for B and T cell development. IL7 plays an essential role in lymphoid cell survival, and in the maintenance of naive and memory T cells.
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Cat. No.: HY-RS23475
Research Areas:  

Others

Il7 Rat Pre-designed siRNA Set A contains three designed siRNAs for Il7 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-P990647

Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology

PF-06342674 is a CHO-expressed humanized antibody that targets IL-7Ra/CD127. PF-06342674 carries a huIgG1 heavy chain and a huλ light chain, with a predicted molecular weight (MW) of 145.14 kDa. The isotype control for PF-06342674 can be referenced as Human IgG1 kappa, Isotype Control (HY-P99001).
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Cat. No.: HY-RS17031
Research Areas:  

Others

Il7 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Il7 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-174597
Target:  

mRNA

Research Areas:  

Inflammation/Immunology

Human IL7R mRNA encodes the human interleukin 7 receptor (IL7R) protein, a receptor for interleukin 7 (IL7). IL7R has been shown to play a critical role in V(D)J recombination during lymphocyte development.
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Cat. No.: HY-P70755
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Interleukin-7; IL-7; IL7
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Cat. No.: HY-P70755G
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Interleukin-7; IL-7; IL7
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Cat. No.: HY-P78550
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Interleukin-7; IL-7; IL7
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