21 Results for "

JCHAIN

" in MedChemExpress (MCE) Product Catalog:
Products (21)

21 Results for "JCHAIN" in MCE Product Catalog:

Cat. No.: HY-P3479
CAS No.: 12584-58-6
Target:  

Insulin Receptor

Research Areas:  

Metabolic Disease

Insulin (swine) is an orally active insulin derived from pigs. Insulin (swine) when administered orally acts as an antigen to reduce the severity of pancreatic lymphocyte infiltration, but has no metabolic effect on blood glucose levels. Insulin (swine) increases glucose oxidation, stimulates lipogenesis, and lowers blood glucose levels. Insulin (swine) can be used in diabetes research .
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Cat. No.: HY-P3432
CAS No.: 2035480-78-3
Research Areas:  

Others

DfTat is a dimer of the prototypical cell-penetrating peptide TAT. DfTat can deliver small molecules, peptides and proteins into live cells with a particularly high efficiency. DfTat labeled with the rhodamine can be used as a tracer for easy detection .
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Cat. No.: HY-P10204
CAS No.: 2416664-25-8
Target:  

Wnt

Research Areas:  

Cancer

FZD7 antagonist 1 (peptide 34) is a dFz7-21 analogue. FZD7 antagonist 1 is an FZD7 antagonist that inhibits the wnt3a with IC50 value of 9.2 nM. FZD7 antagonist 1 blocks TcdB−FZD interaction via targeting FZD receptors .
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Cat. No.: HY-P11361
Target:  

Peptides

Research Areas:  

Metabolic Disease

Des B30 Insulin is a bioactive insulin analogue lacking the B30 amino acid residue. Des B30 Insulin can be used for the study of diabetes .
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Cat. No.: HY-P4890
CAS No.: 1158181-62-4
Relaxin H3 (human) is a relaxin peptide with anti-inflammatory, anti-apoptotic, anti-pyroptotic, anti-migratory, protective and anti-fibrotic activities. Relaxin H3 (human) acts on RXFP1 to generate cAMP and reduce the levels of ATP and ROS. Relaxin H3 (human) inhibits renal inflammatory pyroptosis (pyroptosis), NLRP3 inflammasome activation, caspase-1 activation, IL-1β/IL-18 secretion, collagen synthesis, TGF-β1 signaling pathway, Smad2 phosphorylation, myofibroblast differentiation, TIMP expression, and HRMEC migration. Relaxin H3 (human) activates AMPK, upregulates MFN2 expression, improves mitochondrial quality control and membrane potential, inhibits apoptosis (apoptosis) and pyroptosis, restores retinal ultrastructure, and reverses excessive left ventricular collagen expression. Relaxin H3 (human) can be used in studies related to kidney stones, nephrocalcinosis, diabetic cardiomyopathy, fibrotic cardiomyopathy, and diabetic retinopathy .
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Cat. No.: HY-P10693
CAS No.: 942626-41-7
Target:  

TNF Receptor Bacterial

Research Areas:  

Infection Inflammation/Immunology

CZEN-002 is a derivative of alpha-melanocyte-stimulating hormone that has anti-inflammatory and antibacterial properties, inhibiting the production of TNF-α .
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Cat. No.: HY-P11246
CAS No.: 3057097-31-8
Target:  

RXFP Receptor

Research Areas:  

Metabolic Disease

A13:B7-24-GG is an engineered analogue of insulin-like peptide 5 (INSL5), a selective RXFP4 agonist with a Ki value of 2.29 nM. A13:B7-24-GG has an extremely low binding affinity for RXFP3 (Ki = 602.56 nM) and an inhibitory effect on cAMP (EC50) of 1.17 nM. Activation of RXFP4 by A13:B7-24-GG leads to the recruitment of β-Arrestin2, with an EC50 of 22.39 nM. A13:B7-24-GG can be used for research on chronic constipation .
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Cat. No.: HY-RS07033
Research Areas:  

Others

JCHAIN Human Pre-designed siRNA Set A contains three designed siRNAs for JCHAIN gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS17925
Research Areas:  

Others

Jchain Mouse Pre-designed siRNA Set A contains three designed siRNAs for Jchain gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-P4062
CAS No.: 1200440-65-8
Synonyms: BIL
Target:  

Insulin Receptor

Research Areas:  

Metabolic Disease

Insulin peglispro (BIL) is a basal insulin with a flat, prolonged activity profile. Insulin peglispro can exhibit better glycaemic control compared to conventional insulins .
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Cat. No.: HY-P4890A
Relaxin H3 (human) TFA is a relaxin peptide with anti-inflammatory, anti-apoptotic, anti-pyroptotic, anti-migratory, protective and anti-fibrotic activities. Relaxin H3 (human) TFA acts on RXFP1 to generate cAMP and reduce the levels of ATP and ROS. Relaxin H3 (human) TFA inhibits renal inflammatory pyroptosis (pyroptosis), NLRP3 inflammasome activation, caspase-1 activation, IL-1β/IL-18 secretion, collagen synthesis, TGF-β1 signaling pathway, Smad2 phosphorylation, myofibroblast differentiation, TIMP expression, and HRMEC migration. Relaxin H3 (human) TFA activates AMPK, upregulates MFN2 expression, improves mitochondrial quality control and membrane potential, inhibits apoptosis (apoptosis) and pyroptosis, restores retinal ultrastructure, and reverses excessive left ventricular collagen expression. Relaxin H3 (human) TFA can be used in studies related to kidney stones, nephrocalcinosis, diabetic cardiomyopathy, fibrotic cardiomyopathy, and diabetic retinopathy .
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Cat. No.: HY-RS24395
Research Areas:  

Others

Jchain Rat Pre-designed siRNA Set A contains three designed siRNAs for Jchain gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-P1371
Synonyms: KKWKMRRNQFWIKIQRC CSVEIWD*
Target:  

PKC

Research Areas:  

Others

Pseudo RACK1, a peptide, is a PKC agonist with homologous sequences of PKC. Pseudo RACK1 interacts selectively with β-PKC at an autoregulatory site (RACK-binding site) and activates it in the absence of PKC activators, following inducing PKC-mediated histone phosphorylation .
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Cat. No.: HY-P1372
Target:  

PKC

Research Areas:  

Others

PKC ζ pseudosubstrate, a PKC ζ inhibitor peptide, can be attached to cell permeabilization vector peptide .
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Cat. No.: HY-P10014
CAS No.: 153507-46-1
Target:  

Peptides

Research Areas:  

Cardiovascular Disease

Bibapcitide, a 26 amino acid, inhibits thrombosis .
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Cat. No.: HY-P71744
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: JCHAIN; IgjImmunoglobulin J chain
Species:  
Source:  
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Cat. No.: HY-P74842
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Immunoglobulin J chain; JCHAIN; IGCJ; IGJ
Species:  
Source:  
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Cat. No.: HY-P11548
Target:  

Bacterial

Research Areas:  

Infection

Rattusin is an antimicrobial peptide. Rattusin exerts bactericidal activity by damaging membrane integrity. Rattusin can be used for antimicrobial research .
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Cat. No.: HY-P11625
Target:  

RXFP Receptor

Research Areas:  

Cardiovascular Disease

R9-13 is a fatty acid-conjugated relaxin and an agonist of LGR7 (RXFP1). R9-13 induces sustained pubic symphysis elongation in estrogen-pretreated mice. R9-13 exhibits long-acting pharmacokinetic profiles in rodents, with in vivo activity lasting up to one week after administration. R9-13 can be used in studies related to acute heart failure .
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Cat. No.: HY-P81545
Synonyms: IGCJ antibody; IGJ_HUMAN antibody; Immunoglobulin J chain antibody; Immunoglobulin J polypeptide linker protein for immunoglobulin alpha and mu polypeptides antibody; immunoglobulin joining chain antibody; JCH antibody; JCHAIN antibody; Joining chain of multimeric IgA and IgM antibody

Host:  

Rabbit

Application:  

WB, IHC-P, ICC/IF, FC

Reactivity:  

Human, Mouse

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