![5-[(2-Nitrophenyl)methylene]-2,4-thiazolidinedione](https://file.medchemexpress.com/product_pic/hy-131044.gif "Click to View 5-[(2-Nitrophenyl)methylene]-2,4-thiazolidinedione Product Detail")
Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
19 Results for "
K. pneumonia
" in MedChemExpress (MCE) Product Catalog:
Products (19)
19 Results for "K. pneumonia" in MCE Product Catalog:
35
Category:
Anti-inflammation/Immunoregulatory Disease Research Antibacterial Other Antibiotics Infection Microorganisms Plant Cell Culture Antibiotics Resistance Selection Mammalian Cell Culture Disease Research Fields
Target:
35
Category:
Target:
4
4 Cited Publications
Cat. No.: HY-N2187
CAS No.: 43043-74-9
4
Cat. No.: HY-N0392
CAS No.: 882664-74-6
Target:
Research Areas:
SMT-738 is a bacterial bactericide. SMT-738 targets the small molecules responsible for lipoprotein transport in Enterobacteriaceae, causing abnormal lipoprotein localization and bacterial cell death. SMT-738 inhibits the growth of E. coli and K. pneumoniae. SMT-738 reduces bacterial loads in mouse models of urinary tract infection, bloodstream infection, and pulmonary infection caused by Enterobacterales. SMT-738 can be used in the research of Enterobacteriaceae infections, urinary tract infections, bloodstream infections, and pneumonia .
Category:
Target:
Cat. No.: HY-16566AR
CAS No.: 25389-94-0
Synonyms: Kanamycin A sulfate (Standard)
Category:
Microorganisms Plant Cell Culture Anti-inflammation/Immunoregulatory Antibiotics Resistance Selection Mammalian Cell Culture Disease Research Antibacterial Other Antibiotics
Target:
Cat. No.: HY-174980
KPC-2-IN-3 (Compound 3b) is a KPC-2 inhibitor with IC50 of 0.533 μM and Kiof 0.194 μM. KPC-2-IN-3 has an antimicrobial activity against carbapenem-resistant K. pneumonia K47-25 and reduces bacterial count with a postantibiotic effect in synergy with Meropenem (HY-13678). KPC-2-IN-3 significantly reduces lung bacterial load in a murine pneumonia model .
Cat. No.: HY-147878
CAS No.: 2448358-84-5
Antibacterial agent 111 (Compound 3) is an antibacterial agent with MIC values of 3.90 μg/mL and 0.49 μg/mL against B. cereus and K. pneumonia, respectively. Antibacterial agent 111 firmly binds with tyrosyl-tRNA synthetase residues .
Cat. No.: HY-N3929
CAS No.: 139682-36-3
Category:
Target:
Cat. No.: HY-N1654
CAS No.: 97411-50-2
Category:
Infection Natural Products Plants Azadirachta indica A. Juss. Disease Research Fields Meliaceae
Target:
Cat. No.: HY-131044
CAS No.: 36140-65-5
5-[(2-Nitrophenyl)methylene]-2,4-thiazolidinedione (Compound 4) has antimicrobial, anti-diabetic and antioxidant activities. 5-[(2-Nitrophenyl)methylene]-2,4-thiazolidinedione inhibits B. subtilis, S. aureus, K. pneumonia, E. coli, and S. typhi with MICs of 4.5-9.9 μΜ/mL, and inhibits A. niger and C. albicans with MICs of 4.99 μΜ/mL .
Cat. No.: HY-144255
Research Areas:
Antibacterial agent 70 is an antibacterial agent that interacts with DNA, with a MIC value of 0.5 μg/mL against K. pneumonia and A. baumanii. Antibacterial agent 70 exhibits rapid bactericidal activity, low cytotoxicity to mammalian cells, and low tendency to induce drug resistance. Antibacterial agent 70 intercalates into DNA, disrupts bacterial membrane integrity, increases intracellular ROS production, reduces GSH activity, regulates membrane depolarization, enhances outer membrane permeability, and induces inner membrane damage. Antibacterial agent 70 can be used in studies related to multidrug-resistant bacterial infections and infections caused by drug-resistant Gram-negative pathogens .
Cat. No.: HY-175724
Target:
Research Areas:
MBL-IN-6 (Compound 6d) is a Metallo-β-lactamase (MBL) inhibitor with Kis of 2.6 and 0.08 μM for NDM-1 and VIM-2, respectively. MBL-IN-6 has a synergistic activities with Imipenem (HY-B1369A) on MBL-producing clinical isolates (such as E. coli SI-M001, K. pneumonia T2301 and S. marcescens SI-1591) with MICs of 2-64 μg/mL. MBL-IN-6 does not have off-target effects without ACE-1 inhibition activity. MBL-IN-6 can be used for antimicrobial resistance research .
Cat. No.: HY-N0392R
CAS No.: 882664-74-6
Cat. No.: HY-107044
CAS No.: 364069-14-7
Target:
Research Areas:
DK 507k is an orally active 8-methoxyquinolone Antibacterial agent. DK 507k targets DNA gyrase subunit A (GyrA) and modulates the function of GyrA. DK 507k inhibits the growth of various Gram-positive and Gram-negative bacteria, including Pseudomonas aeruginosa and Methicillin (HY-121544)-resistant Staphylococcus aureus. DK 507k eliminates Penicillin-tolerant Streptococcus pneumoniae from the lungs of mice. DK 507k can be used in research related to sepsis and *Streptococcus pneumoniae* pneumonia .
Cat. No.: HY-179632
CAS No.: 2349248-62-8
Antibacterial agent 311 (Compound 4f) is an antibacterial agent. Antibacterial agent 311 exhibits antibacterial activities against P. aeruginosa, S. aureus, E. coli, K. pneumonia, E. CTXM1, E. NDM1 with MICs of 0.8, 1, 1, 1, 0.7, 0.7 mg/mL .
- 1
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
