Kanamycin (Standard)
Based on 1 Customer Validation
Kanamycin (Standard) (Kanamycin A (Standard)) is the analytical standard of Kanamycin (HY-16566). This product is intended for research and analytical applications. Kanamycin (Kanamycin A) is an antibacterial agent. Kanamycin blocks Kir4.1 channels. Kanamycin inhibits bacterial mRNA translation and exerts bactericidal effects against Gram-positive, Gram-negative, and acid-resistant microorganisms. Kanamycin produces ROS and superoxide and induces caspase-3-mediated apoptosis. Kanamycin inhibits biofilms and reduces persister bacteria, and reduces Mycobacterium tuberculosis within macrophages. Kanamycin can be used in research on bacterial infections, urinary tract infections, tuberculosis, and Staphylococcus aureus-induced peritonitis.
For research use only. We do not sell to patients.
- Purity : 99.55%
- CAS No.: 59-01-8
- Formula: C18H36N4O11
- Molecular Weight:484.50
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Product Information
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Chemical Information
- Purity & Documentation
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Help & FAQs
Product Information
Information
Application
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
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CAS No. 59-01-8
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Appearance Solid
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Molecular Weight 484.50
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Formula C18H36N4O11
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Color White to off-white
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SMILES
O[C@H]1[C@](O[C@@H]2[C@@H](N)C[C@@H](N)[C@H](O[C@@]3([H])O[C@H](CO)[C@@H](O)[C@H](N)[C@H]3O)[C@H]2O)([H])O[C@H](CN)[C@@H](O)[C@@H]1O
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Synonyms
Kanamycin A (Standard)
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
[2]. Peng B, et al. Exogenous alanine and/or glucose plus kanamycin kills antibiotic-resistant bacteria. Cell metabolism. 2015 Feb 03;21(2):249-262. [Content Brief]
[3]. Brezden A, et al. Dual Targeting of Intracellular Pathogenic Bacteria with a Cleavable Conjugate of Kanamycin and an Antibacterial Cell-Penetrating Peptide. Journal of the American Chemical Society. 2016 Aug 31;138(34):10945-9. [Content Brief]
[4]. Hawkins Jr JE. XLIX The Ototoxicity of Kanamycin. Annals of Otology, et al. 1959 Sep;68(3):698-715.
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Kanamycin (Standard) Related Classifications
HY-16566R Related Classifications
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Keywords
- Kanamycin (Standard)
- 59-01-8
- Kanamycin A (Standard)
- Reference Standards
- Bacterial
- Potassium Channel
- Reactive Oxygen Species (ROS)
- Caspase
- Apoptosis
- KcsA
- Gram-negative
- Gram-positive
- Kir4.1 channels
- acid-fast organisms
- caspase-3-mediated apoptosis
- mRNA translation
- nephrotoxicity
- ototoxicity
- reactive oxygen species
- superoxide
- Inhibitor
- inhibitor
- inhibit