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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
29 Results for "
Kir3
" in MedChemExpress (MCE) Product Catalog:
Products (29)
29 Results for "Kir3" in MCE Product Catalog:
11
11 Publications Verification
Synonyms: NP-120 tartrate; RC-61-91 tartrate
11
11 Publications Verification
Synonyms: NP-120; RC-61-91
Research Areas:
Ifenprodil (NP-120), a cerebral vasodilator, is a noncompetitive NMDA receptor antagonist. Ifenprodil exerts high affinity at NR1A/NR2B receptors (IC50=0.34 μM) over 400-fold than at NR1A/NR2A receptors (IC50=146 μM) . Ifenprodil is an α1 adrenergic receptor antagonist. Ifenprodil inhibits GIRK (Kir3), reduces inward currents through the basal GIRK activity. Ifenprodil has reliable inhibitory effects against A/H1N1 strains (EC50 of 6.6 µM). Ifenprodil has neuroprotective, anticonvulsant and antinociceptive effects. Ifenprodil can be used for the study of cerebrovascular diseases and peripheral arterial obliterative disease .
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1 Cited Publications
Target:
Research Areas:
VU0810464 is a potent and selective non-ureaG protein-gated inwardly-rectifying potassium channels (GIRK, Kir3) activator. VU0810464 displays nanomolar potency for neuronal (EC50=165 nM) and GIRK1/4 (EC50=720 nM) channels with improved brain penetration .
Cat. No.: HY-P99369
CAS No.: 2187368-16-5
Synonyms: IPH 4102; Anti-Kir3DL2/CD158k Reference Antibody (lacutamab)
Cat. No.: HY-167548
CAS No.: 383907-42-4
Cat. No.: HY-12882AR
CAS No.: 23210-58-4
Synonyms: NP-120 tartrate (Standard); RC-61-91 tartrate (Standard)
Cat. No.: HY-RS07308
Target:
Research Areas:
KIR3DL1 Human Pre-designed siRNA Set A contains three designed siRNAs for KIR3DL1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS07310
Target:
Research Areas:
KIR3DL3 Human Pre-designed siRNA Set A contains three designed siRNAs for KIR3DL3 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS07311
Target:
Research Areas:
KIR3DS1 Human Pre-designed siRNA Set A contains three designed siRNAs for KIR3DS1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS20211
Target:
Research Areas:
Kir3dl1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Kir3dl1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS26716
Target:
Research Areas:
Kir3dl1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Kir3dl1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-W197393
CAS No.: 553-30-0
Research Areas:
Proflavine sulfate is a multifunctional acridine compound. 3,6-Diaminoacridine sulfate is an acridine dye and also a DNA inserter. Proflavine sulfate is a potent broad-spectrum antibacterial agent, and its mechanism is to insert into bacterial DNA, interfering with replication and transcription, causing bacterial lysis. 3,6-Diaminoacridine sulfate is a Kir3.2 potassium channel blocker and can be used to study the neurological phenotype of Down syndrome. 3,6-Diaminoacridine sulfate can penetrate the stratum corneum of the skin and accumulate in the cell nucleus and long-term exposure may induce skin cancer or other malignant tumors [3].
Cat. No.: HY-RS07309
Target:
Research Areas:
KIR3DL2 Human Pre-designed siRNA Set A contains three designed siRNAs for KIR3DL2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P704734
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CD158Z; Kir2DS2; Kir3DL7; Kir44; KirC1; Kir3DL3
Cat. No.: HY-P705054
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: CD158Z; Kir2DS2; Kir3DL7; Kir44; KirC1; Kir3DL3
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
