38 Results for "

L-1210 leukemia cells

" in MedChemExpress (MCE) Product Catalog:
Products (38)

38 Results for "L-1210 leukemia cells" in MCE Product Catalog:

5
5 Cited Publications
Cat. No.: HY-N2306
CAS No.: 57576-44-0
Synonyms: Aclarubicin
Aclacinomycin A (Aclarubicin) is an orally active and potent anthracycline antitumor antibiotic. Aclacinomycin A is an inhibitor of topoisomerase I and II. Aclacinomycin A inhibits synthesis of nucleic acid, especially RNA. Aclacinomycin A might inhibit the 26S protease complex as well as the ubiquitin-ATP-dependent proteolysis .
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Cat. No.: HY-129983
CAS No.: 5116-24-5
Purity:  99.93%
Target:  

HSV

Research Areas:  

Infection Cancer

5-Hydroxymethyl-2'-deoxyuridine is a nucleoside analog. 5-Hydroxymethyl-2'-deoxyuridine inhibits the replication of multiple human leukemia cell lines with IC50 values of 1.7-5.8 μM. 5-Hydroxymethyl-2'-deoxyuridine prolongs the survival of mice carrying L1210 leukemia. 5-Hydroxymethyl-2'-deoxyuridine can be used for the research of cell replication and leukemia .
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Cat. No.: HY-W590549
CAS No.: 7212-69-3
Synonyms: DODAC
Target:  

Liposome

Research Areas:  

Cancer

Dioleyldimethylammonium chloride (DODAC) is a positively charged lipid promoter with membrane-disrupting activity, which is often formulated into cationic liposomes with dioleoylphosphatidylethanolamine. Dioleyldimethylammonium chloride is used in gene transfection research; through electrostatic interactions, it effectively promotes the binding of programmable fusion vesicles to cells and induces membrane disruption. Dioleyldimethylammonium chloride is also applied in studies on L1210 leukemia and LS180 human colon cancer .
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Cat. No.: HY-N2306A
CAS No.: 75443-99-1
Synonyms: Aclarubicin hydrochloride
Aclacinomycin A (Aclarubicin) hydrochloride is an orally active and potent anthracycline antitumor antibiotic. Aclacinomycin A hydrochloride is an inhibitor of topoisomerase I and II. Aclacinomycin A hydrochloride inhibits synthesis of nucleic acid, especially RNA. Aclacinomycin A hydrochloride might inhibit the 26S protease complex as well as the ubiquitin-ATP-dependent proteolysis .
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Cat. No.: HY-B1713A
CAS No.: 1069-31-4
Synonyms: DL-(±)-Ornithine hydrochloride
DL-Ornithine (DL-(±)-Ornithine) hydrochloride is an amino acid and also a urea cycle promoter. DL-Ornithine hydrochloride has the characteristics of low metabolic rate and rapid excretion, and only the L-enantiomer undergoes decarboxylation. In mice inoculated with L-1210 leukemia cells, DL-Ornithine hydrochloride is excreted in urine in its original form, and its conversion to carbon dioxide within 24 h is negligible. DL-Ornithine hydrochloride is mainly used in the urea cycle to eliminate excess nitrogen in the body and protect the kidneys .
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Cat. No.: HY-129861
CAS No.: 69075-47-4
Target:  

HSV

Research Areas:  

Infection Cancer

5'-Ethynyl-2'-deoxycytidine is an inhibitor for HSV, that inhibits the cytopathic effect of HSV-1 in primary rabbit kidney cell with a MIC of 0.2 μg/mL. 5'-Ethynyl-2'-deoxycytidine inhibits the proliferation of leukemia L1210 cell with an IC50 of 64.5 μg/mL .
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Cat. No.: HY-N2306R
CAS No.: 57576-44-0
Synonyms: Aclarubicin (Standard)
Aclacinomycin A (Standard) is the analytical standard of Aclacinomycin A. This product is intended for research and analytical applications. Aclacinomycin A (Aclarubicin) is an orally active and potent anthracycline antitumor antibiotic. Aclacinomycin A is an inhibitor of topoisomerase I and II. Aclacinomycin A inhibits synthesis of nucleic acid, especially RNA. Aclacinomycin A might inhibit the 26S protease complex as well as the ubiquitin-ATP-dependent proteolysis .
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Cat. No.: HY-129564
CAS No.: 510-18-9
Target:  

Antibiotic

Research Areas:  

Cancer

Acetomycin is an antibiotic. Acetomycin inhibits the growth of CT-8 human colon adenocarcinoma cells (IC50: 1.5 μg/mL) and L1210 murine leukemia cells (IC50: 2.2 μg/mL). Acetomycin can be isolated from actinomycete WP-2661 .
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Cat. No.: HY-N8519
CAS No.: 104542-46-3
Urdamycin B is an antibiotic that effectively inhibits fungi and bacteria. Urdamycin B also exhibits anti-proliferative activity against mouse leukemia cells L1210. Urdamycin B can be obtained from the metabolic products of Streptomyces fradiae. Urdamycin B can be used for research on cancer as well as bacterial and fungal infections .
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Cat. No.: HY-P991016
CAS No.: 2928515-21-1
Synonyms: PT-217

Target:  

CD47

Research Areas:  

Inflammation/Immunology

Peluntamig (PT-217) is a bispecific antibody targeting DLL3 and CD47. The antibody arms of Peluntamig specifically bind to DLL3 on small cell lung cancer tumor cells while blocking the CD47-SIRPa interaction, thereby effectively stimulating macrophage phagocytosis and inducing NK cell-mediated cytotoxicity. Peluntamig exhibits significant anti-tumor activity against small cell lung cancer and also has favorable safety profiles. Peluntamig can be used in a variety of tumor-related studies including those on small cell lung cancer and L1210 leukemia .
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Cat. No.: HY-N15034
CAS No.: 16870-91-0
7-Hydroxyguanine is an antibiotic that can inhibit the growth of L1210 leukemia cells .
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Cat. No.: HY-N14787
CAS No.: 82501-56-2
Basidalin has the ability of anti-Gram-positive bacteria, negative bacteria and inhibition of mouse leukemia L-1210 cell.
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Cat. No.: HY-N10206
CAS No.: 1319729-88-8
11-epi-Chaetomugilin I is a metabolite found in Chaetomium globosum. 11-epi-Chaetomugilin I exhibits significant cytotoxic activity against the murine P388 leukemia cell line, the human HL-60 leukemia cell line, the murine L1210 leukemia cell line, and the human KB epidermoid carcinoma cell line .
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Cat. No.: HY-N14697
CAS No.: 133914-58-6
Cytorhodin X is a cytotoxic antibiotic. Cytorhodin X can inhibit the proliferation of L1210 murine leukemia cells, with an ED50 of 0.36 μM .
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Cat. No.: HY-N14764
CAS No.: 79127-36-9
2-Hydroxyaclacinomycin A is an anthracycline antibiotic. 2-Hydroxyaclacinomycin A has the activity of inhibiting leukemia L-1210 cells, and the IC50 for RNA and DNA synthesis is 0.10 μg/mL and 0.95 μg/mL, respectively .
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Cat. No.: HY-N14652
CAS No.: 99260-73-8
Glycocinnasperimicin D is a glycoside cinnamyl imide histamine antibiotic. Glycocinnasperimicin D has the activity of anti-Gram positive bacteria and negative bacteria. Glycocinnasperimicin D inhibits leukemia L1210 cell with an IC50 of 2.0 μg/mL .
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Cat. No.: HY-N14802
CAS No.: 103106-23-6
Napyradiomycin B1 is an antibiotic with anti-Gram-positive bacteria and mycobacterial activity. Napyradiomycin B1 almost none to Gram-negative bacteria and fungi. IC50 (μg/mL) of leukemia L-1210 cells is 2.2 .
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Cat. No.: HY-N14806
CAS No.: 103106-20-3
Napyradiomycin C1 is an antibiotic with anti-Gram-positive bacteria and mycobacterial activity. Napyradiomycin C1 almost none to Gram-negative bacteria and fungi. IC50 (μg/mL) of leukemia L-1210 cells is 9.2 .
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Cat. No.: HY-N14776
CAS No.: 55511-85-8
11-Demethyltomaymycin is an antibiotic. 11-Demethyltomaymycin has antiviral activity against Escherichia coli T1 and T3 phages and antibacterial activity against Gram-positive bacteria. In addition, 11-Demethyltomaymycin is cytotoxic to leukemia L1210 cells .
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Cat. No.: HY-W194107
CAS No.: 1209784-87-1
Target:  

DNA/RNA Synthesis

Research Areas:  

Cancer

Antitumor agent-152 (Compound 5) is a specific substrate and inhibitor of deoxycytidine kinase (dCK) with anticancer activity. Antitumor agent-152 can inhibit the uptake of 3H-dC in L1210 leukemia cells with an IC50 value of 1.12 μM .
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