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United States

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Referencia número: HY-N14697

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Cytorhodin X

Cytorhodin X is a cytotoxic antibiotic. Cytorhodin X can inhibit the proliferation of L1210 murine leukemia cells, with an ED₅₀ of 0.36 μM.

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No. CAS: 133914-58-6
Fòrmula: C₄₈H₆₈N₂O₁₅
Peso molecular:913.06

Almacenamiento:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (271 KB)

Cytorhodin X Chemical Structure

No. CAS: 133914-58-6

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Actividad biológica

Descripciòn

Cytorhodin X is a cytotoxic antibiotic. Cytorhodin X can inhibit the proliferation of L1210 murine leukemia cells, with an ED₅₀ of 0.36 μM^[1].

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Chemical Information

No. CAS 133914-58-6
Peso molecular 913.06
Fòrmula C₄₈H₆₈N₂O₁₅
SMILES

O=C1C2=C(C(O)=CC=C2)C(C3=C1C(O)=C4[C@@H](O[C@@H]5O[C@@H](C)[C@@H](O[C@@H]6O[C@@H](C)[C@@H](O[C@@H]7O[C@@H](C)[C@@H](O)CC7)CC6)[C@@H](N(C)C)C5)[C@@](CCC4=C3O)(OC8O[C@@H](C)[C@@H](O)[C@@H](N(C)C)C8)CC)=O
Structure Classification
- Quinones
- Naphthalene Quinones
Initial Source
- Microorganisms
Streptomyces sp. HPLY-11472 (DSM 2658).
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

Protocolo

All Cell Biology

Cell Viability Determination by MTT Colorimetric Assay
The following protocol uses the MTT colorimetric assay as a classic literature-established method for assessing cell viability/metabolic activity in cultured mammalian cells. MTT[3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide] is reduced by metabolically active cells to a colored formazan product; the amount of formazan is quantified spectrophotometrically and provides an indirect measure of metabolically active viable cells. Importantly, MTT reduction reflects cellular oxidoreductase/metabolic activity rather than an absolute direct count of living cells, so changes in cellular metabolism can alter the signal independently of cell number.

Pureza y Documentación

Select Batch:

Pureza: 99.98%

Assay: 99.98%

ee.: 99.98%

Ficha de datos (271 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instrucciones de manejo (2659 KB)

Referencias

[1]. Hedtmann U, et al. The new cytotoxic antibiotic cytorhodin X, an unusual anthracyclinone-9 alpha-glycoside. J Antibiot (Tokyo). 1992 Aug;45(8):1373-5. [Content Brief]

Calculators

Calculadora de molaridad

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculadora de dilución

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

Minimum order quantity

100 mg

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