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Results for "

L-proline

" in MedChemExpress (MCE) Product Catalog:

By Targets:	ADC Linker (3) Amino Acid Derivatives (17) Apoptosis (4) Bacterial (1) Biochemical Assay Reagents (7) Drug Intermediate (10) Endogenous Metabolite (21) Environmental Pollutants (1) GABA Receptor (4) iGluR (1) Isotope-Labeled Compounds (5) Liposome (1) Mitochondrial Metabolism (1) mTOR (3) NO Synthase (5) PROTAC Linkers (3) Reference Standards (7) SGLT (1)
By Research Areas:	Cancer (11) Cardiovascular Disease (7) Endocrinology (3) Infection (1) Inflammation/Immunology (8) Metabolic Disease (9) Neurological Disease (6)
Click Chemistry:	Alkynes (1)
Oligonucleotides:	Solubilizing Agents (1)

Inhibitors & Agonists

Biochemical Assay Reagents

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Isotope-Labeled Compounds

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Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-Y0252

*L-Proline* 5+ Cited Publications	Endogenous Metabolite mTOR Apoptosis	Others
L-Proline is one of the twenty amino acids used in living organisms as the building blocks of proteins.

HY-N0455

L-Arginine 20+ Cited Publications	Environmental Pollutants Endogenous Metabolite NO Synthase	Cardiovascular Disease Inflammation/Immunology
L-Arginine ((S)-(+)-Arginine) is the substrate for the endothelial nitric oxide synthase (eNOS) to generate NO. L-Arginine is transported into vascular smooth muscle cells by the cationic amino acid transporter family of proteins where it is metabolized to nitric oxide (NO), polyamines, or L-proline. L-Arginine is a potent vasodilator, and can be used to induce experimental acute pancreatitis .

HY-N0455A

L-Arginine hydrochloride Maximum Cited Publications 23 Publications Verification (S)-(+)-Arginine hydrochloride	NO Synthase Endogenous Metabolite	Cardiovascular Disease Inflammation/Immunology
L-Arginine ((S)-(+)-Arginine) is the substrate for the endothelial nitric oxide synthase (eNOS) to generate NO. L-Arginine is transported into vascular smooth muscle cells by the cationic amino acid transporter family of proteins where it is metabolized to nitric oxide (NO), polyamines, or L-proline. L-Arginine is a potent vasodilator, and can be used to induce experimental acute pancreatitis .

HY-Y0252R

L-Proline (Standard)	Reference Standards Endogenous Metabolite mTOR Apoptosis	Inflammation/Immunology
L-Proline (Standard) is the analytical standard of L-Proline. This product is intended for research and analytical applications. L-Proline is one of the twenty amino acids used in living organisms as the building blocks of proteins.

HY-Y0252S

L-Proline-13C5	Endogenous Metabolite	Others
L-Proline- ¹³C₅ is the ¹³C-labeled L-Proline. L-Proline is one of the twenty amino acids used in living organisms as the building blocks of proteins.

HY-W016887

Glycyl-L-proline H-Gly-Pro-OH; Gly-Pro	Endogenous Metabolite Apoptosis	Metabolic Disease Cancer
Glycyl-L-proline (H-Gly-Pro-OH) is a dipeptide. Glycyl-L-proline can induce MCF-7 cells apoptosis. Glycyl-L-proline can enhance the inhibitory effect of the PRODH/POX knockout on collagen and DNA biosynthesis. Glycyl-L-proline can inhibit Gly-Sar and L-proline transport. Glycyl-L-proline can be used for the researches of cancer and metabolic disease, such as breast cancer .

HY-14894A

Ipragliflozin L-Proline 5+ Cited Publications	SGLT	Metabolic Disease
Ipragliflozin (L-Proline) is a highly potent and selective SGLT2 inhibitor with an IC₅₀ of 2.8 nM; little and NO potency for SGLT1/3/4/5/6.

HY-17490

Oxaceprol 1 Publications Verification N-Acetyl-L-hydroxyproline	Amino Acid Derivatives	Inflammation/Immunology
Oxaceprol (N-Acetyl-L-hydroxyproline), an orally active derivative of L-proline, possesses distinct anti-inflammatory activity. Oxaceprol is usually used for the research of osteoarthritis and rheumatoid arthritis .

HY-Y0252S1

L-Proline-d3	Endogenous Metabolite	Others
L-Proline-d₃ is the deuterium labeled L-Proline. L-Proline is one of the twenty amino acids used in living organisms as the building blocks of proteins.

HY-Y0755

*N-Boc-4-hydroxy-L-proline* methyl ester**	ADC Linker PROTAC Linkers	Cancer
N-Boc-cis-4-hydroxy-L-proline methyl ester is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). N-Boc-cis-4-hydroxy-L-proline methyl ester is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[2

HY-Y0252S5

L-Proline-d7	Endogenous Metabolite	Others
L-Proline-d₇ is the deuterium labeled L-Proline. L-Proline is one of the twenty amino acids used in living organisms as the building blocks of proteins.

HY-N0455R

L-Arginine (Standard)	Reference Standards NO Synthase Endogenous Metabolite	Cardiovascular Disease Cancer
L-Arginine (Standard) is the analytical standard of L-Arginine. This product is intended for research and analytical applications. L-Arginine ((S)-(+)-Arginine) is the substrate for the endothelial nitric oxide synthase (eNOS) to generate NO. L-Arginine is transported into vascular smooth muscle cells by the cationic amino acid transporter family of proteins where it is metabolized to nitric oxide (NO), polyamines, or L-proline. L-Arginine is a potent vasodilator, and can be used to induce experimental acute pancreatitis .

HY-40114

Boc-L-proline	Amino Acid Derivatives Biochemical Assay Reagents Drug Intermediate	Others
Boc-L-proline is an amino acid derivative. As an important intermediate in organic synthesis, Boc-L-proline can be used for peptide synthesis .

HY-21754

Hygric acid N-Methyl-L-proline	Others	Others
Hygric acid (N-Methyl-L-proline) is a proline analog that is found in bergamot, various citrus juices, and alfalfa seedlings .

HY-40136

cis-4-Hydroxy-L-proline	Endogenous Metabolite	Cardiovascular Disease Metabolic Disease Endocrinology Cancer
cis-4-Hydroxy-L-proline is an orally active proline analog and collagen production inhibitor. cis-4-Hydroxy-L-proline inhibits cell growth by preventing the deposition of triple helical collagen on the cell layer. cis-4-Hydroxy-L-proline inhibits N-nitrosomethylurea-induced breast tumor growth. cis-4-Hydroxy-L-proline improves lung compliance and reduces prostate weight. cis-4-Hydroxy-L-proline can be used in the study of hypoxic pulmonary hypertension .

HY-142035

N-Propargylglycine 1 Publications Verification	Mitochondrial Metabolism	Neurological Disease Metabolic Disease Inflammation/Immunology Cancer
N-Propargylglycine is a brain-penetrant and orally active PRODH inhibitor. N-Propargylglycine covalently modifies enzyme-bound FAD and active site lysine, causing enzyme structural distortion, protein decay, and irreversible inhibition of proline and 4-hydroxyproline catabolism. N-Propargylglycine induces UPRmt, upregulates mitochondrial chaperones and YME1L1, enhances mitochondrial proteostasis, blocks astrocytic L-proline consumption, and abolishes L-proline’s ATP-maintaining and viability-protective effects. N-Propargylglycine stimulates neural processes, increases brain proline, hydroxyproline, and sarcosine levels, partially normalizes Huntington’s disease whole brain transcriptomes. N-Propargylglycine reduces hyperoxaluria, prevents calcium oxalate stone formation, reduces kidney tubular damage, and restores weight and survival in Grhpr knockout mice. N-Propargylglycine can be used for the research of breast cancer, neurodegenerative disorders, Huntington’s disease, and primary hyperoxaluria type 2 .

HY-Y0252S4

L-Proline-13C5,15N	Endogenous Metabolite	Others
L-Proline- ¹³C₅,1- ¹⁵N is the ¹³C- and ¹⁵N-labeled L-Proline. L-Proline is one of the twenty amino acids used in living organisms as the building blocks of proteins.

HY-N2368A

Arecaidine hydrochloride 1 Publications Verification	GABA Receptor	Neurological Disease
Arecaidine hydrochloride, a pyridine alkaloid, is a potent GABA uptake inhibitor. Arecaidine hydrochloride is a substrate of H ⁺-coupled amino acid transporter 1 (PAT1, SLC36A1) and competitively inhibits L-proline uptake .

HY-W016042

N-Cbz-Hydroxy-L-proline	Drug Intermediate	Others
N-Cbz-Hydroxy-L-proline is a chiral N-Cbz-protected amino acid derivative. N-Cbz-Hydroxy-L-proline is commonly used in the synthesis of polypeptides and pharmaceutical intermediates. N-Cbz-Hydroxy-L-proline undergoes decarboxylation under AlCl₃/HFIP conditions .

HY-W015897

3,4-Dehydro-L-proline	Amino Acid Derivatives	Others
3,4-Dehydro-L-proline is aamino acids and their derivatives.

HY-Y0252S3

L-Proline-13C	Endogenous Metabolite	Others
L-Proline- ¹³C is the ¹³C-labeled L-Proline. L-Proline is one of the twenty amino acids used in living organisms as the building blocks of proteins.

HY-W008129

H-D-cis-Hyp-OH	Drug Intermediate Bacterial	Infection
H-D-cis-Hyp-OH is a proline derivative and also a substrate of cis-4-hydroxy-D-proline dehydrogenase from Sinorhizobium meliloti. H-D-cis-Hyp-OH serves as a starting material for the synthesis of conformationally constrained pyrrolidine PNA adenine monomers .

HY-W004114

N-Acetyl-L-proline	Amino Acid Derivatives Endogenous Metabolite	Others
N-Acetyl-L-proline is aproline derivatives.

HY-144250S

*Glycyl-L-proline-15N,d2 trifluoroacetate*	Isotope-Labeled Compounds	Others
Glycyl-L-proline- ¹⁵N,d₂ (trifluoroacetate) is a ¹⁵N-labeled and deuterium labeled Glycyl-L-proline .

HY-Y0252S2

L-Proline-15N	Endogenous Metabolite	Others
L-Proline- ¹⁵N is the ¹⁵N-labeled L-Proline. L-Proline is one of the twenty amino acids used in living organisms as the building blocks of proteins .

HY-N2368B

Arecaidine hydrobromide 1 Publications Verification	GABA Receptor	Neurological Disease
Arecaidine hydrobromide, a pyridine alkaloid, is a potent GABA uptake inhibitor. Arecaidine hydrobromide is a substrate of H ⁺-coupled amino acid transporter 1 (PAT1, SLC36A1) and competitively inhibits L-proline uptake .

HY-100836

trans-4-Carboxy-L-proline	iGluR	Neurological Disease
Trans-4-Carboxy-L-prolineis a selective glutamate transporter inhibitor .

HY-W003222

N-tert-Boc-cis-4-fluoro-L-proline	Drug Intermediate	Metabolic Disease
N-tert-Boc-cis-4-fluoro-L-proline (Compound 11) is a drug intermediate for the synthesis of 4-fluoropyrrolidine-2-carbonitrile DPP-4 inhibitor. N-tert-Boc-cis-4-fluoro-L-proline can be used to study type 2 diabetes .

HY-W016887R

*Glycyl-L-proline* (Standard)** H-Gly-Pro-OH (Standard); Gly-Pro (Standard)	Reference Standards Endogenous Metabolite	Metabolic Disease
H-Gly-Pro-OH (Standard) is the analytical standard of H-Gly-Pro-OH. This product is intended for research and analytical applications. H-Gly-Pro-OH is an end product of collagen metabolism that is further cleaved by prolidase.

HY-167566

Poly-L-proline	Biochemical Assay Reagents
Poly-L-proline is a kind of biochemical reagent.

HY-WAA0253

L-Proline monohydrochloride	Amino Acid Derivatives	Others
L-Proline monohydrochloride is a proline derivative .

HY-W046071

N-Boc-trans-4-fluoro-L-proline	Drug Intermediate	Others
N-Boc-trans-4-fluoro-L-proline is a non-natural amino acid substitute used to construct monoclonal antibodies that specifically target the seed conformation of tau protein .

HY-W002886

N-Boc-cis-4-hydroxy-L-proline	ADC Linker PROTAC Linkers	Cancer
N-Boc-cis-4-hydroxy-L-proline is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). N-Boc-cis-4-hydroxy-L-proline is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[2

HY-134935

L-Proline β-naphthylamide hydrochloride	Amino Acid Derivatives	Others
L-Proline β-naphthylamide (hydrochloride) is a proline derivative .

HY-41318

*N-Z-L-proline* methyl ester** 1,2-Pyrrolidinedicarboxylic acid, 2-methyl 1-(phenylmethyl) ester, (S)-; Methyl (S)-N-(benzyloxycarbonyl)prolinate	Amino Acid Derivatives	Others
N-Z-L-proline methyl ester is a proline derivative .

HY-W011155

L-Proline p-nitroanilide TFA P-pNA TFA	Amino Acid Derivatives	Others
L-Proline p-nitroanilide (P-pNA) TFA is aproline derivatives.

HY-W019213

*cis-4-Hydroxy-L-proline* hydrochloride**	ADC Linker PROTAC Linkers	Cancer
cis-4-Hydroxy-L-proline hydrochloride is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). cis-4-Hydroxy-L-proline hydrochloride is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

HY-40136S

*cis-4-Hydroxy-L-proline-d3*	Isotope-Labeled Compounds Endogenous Metabolite	Cardiovascular Disease Metabolic Disease Endocrinology Cancer
cis-4-Hydroxy-L-proline-d₃ is the deuterium labeled cis-4-Hydroxy-L-proline (HY-40136). cis-4-Hydroxy-L-proline is an orally active proline analog and collagen production inhibitor. cis-4-Hydroxy-L-proline inhibits cell growth by preventing the deposition of triple helical collagen on the cell layer. cis-4-Hydroxy-L-proline inhibits N-nitrosomethylurea-induced breast tumor growth. cis-4-Hydroxy-L-proline improves lung compliance and reduces prostate weight. cis-4-Hydroxy-L-proline can be used in the study of hypoxic pulmonary hypertension .

HY-137859

L-Proline 7-amido-4-methylcoumarin hydrobromide	Biochemical Assay Reagents	Others
L-Proline 7-amido-4-methylcoumarin hydrobromide is a biochemical reagent.

HY-Y0252S8

L-Proline-d4	Isotope-Labeled Compounds Endogenous Metabolite Apoptosis mTOR	Others
L-Proline-d₄ is the deuterium labeled L-Proline (HY-Y0252). L-Proline is one of the twenty amino acids used in living organisms as the building blocks of proteins.

HY-W014540

L-Proline tert-butyl ester hydrochloride tert-Butyl L-prolinate hydrochloride	Biochemical Assay Reagents
L-Proline tert-butyl ester hydrochloride (tert-Butyl L-prolinate hydrochloride) is a biologically active compound that has the activity of inhibiting cysteine and cathepsins, and is therefore widely used in the research and development of protease inhibitors. The characteristics of L-Proline tert-butyl ester hydrochloride make it of great significance in the field of biochemistry.

HY-131096

L-Proline 4-methoxy-β-naphthylamide hydrochloride H-Pro-4MβNA hydrochloride	Drug Intermediate	Cancer
L-Proline 4-methoxy-β-naphthylamide hydrochloride (H-Pro-4MβNA hydrochloride) can be used for Fap-activated anti-tumor compounds preparaction .

HY-168772

*Glycyl-L-Proline* TFA** H-Gly-Pro-OH TFA	Amino Acid Derivatives	Others
Glycyl-L-Proline TFA (H-Gly-Pro-OH TFA) is a dipeptide, which is composed of a glycine and a L-proline. Glycyl-L-Proline TFA can be used in research about the co-relationship between transmembrane potential/proton gradient and intestinal transport .

HY-40118

Boc-Pro-OMe Boc-L-proline methyl ester	Liposome	Others
Boc-Pro-OMe (Boc-L-proline methyl ester) is a lipid compound that can be used for liposome preparation. Liposomes are the main component of vesicles with concentric phospholipid bilayer membranes, which can be used to construct drug delivery systems for anti-cancer and anti-infection fields. Highly polar water-soluble loads can be captured in the internal aqueous space of liposomes, while lipophilic loads can be distributed into the lipid bilayer and become part of the lipid bilayer. Especially for the delivery of antisense oligonucleotides, it can overcome the problems of inefficient cellular uptake and rapid loss in the body.

HY-W414638

Fmoc-pro-osu N-Fmoc-L-proline N-succinimidyl ester	Drug Intermediate	Others
Fmoc-pro-osu (N-Fmoc-L-proline N-succinimidyl esterl) is a drug intermediate for synthesis of various active compounds.

HY-W022138

N-Tert-Butoxycarbonyl-(4S)-4-Methoxymethyl-L-proline	Amino Acid Derivatives	Others
N-Tert-Butoxycarbonyl-(4S)-4-Methoxymethyl-L-proline is a proline derivative .

HY-N0455C

L-Arginine arginine	NO Synthase Endogenous Metabolite	Cardiovascular Disease Inflammation/Immunology
L-Arginine arginine is the substrate for the endothelial nitric oxide synthase (eNOS) to generate NO. L-Arginine is transported into vascular smooth muscle cells by the cationic amino acid transporter family of proteins where it is metabolized to nitric oxide (NO), polyamines, or L-proline. L-Arginine is a potent vasodilator, and can be used to induce experimental acute pancreatitis .

HY-N2368AR

Arecaidine hydrochloride (Standard)	Reference Standards GABA Receptor	Neurological Disease
Arecaidine hydrochloride, a pyridine alkaloid, is a potent GABA uptake inhibitor. Arecaidine hydrochloride is a substrate of H+-coupled amino acid transporter 1 (PAT1, SLC36A1) and competitively inhibits L-proline uptake .

HY-CE01671

L-Proline-CoA L-proline-coenzyme A	Biochemical Assay Reagents	Metabolic Disease
L-Proline-CoA (L-Proline-coenzyme A) is a coenzyme A derivative .

HY-40136R

*cis-4-Hydroxy-L-proline* (Standard)**	Reference Standards Endogenous Metabolite	Cardiovascular Disease Metabolic Disease Endocrinology Cancer
cis-4-Hydroxy-L-proline (Standard) is the analytical standard of cis-4-Hydroxy-L-proline (HY-40136). This product is intended for research and analytical applications. cis-4-Hydroxy-L-proline is an orally active proline analog and collagen production inhibitor. cis-4-Hydroxy-L-proline inhibits cell growth by preventing the deposition of triple helical collagen on the cell layer. cis-4-Hydroxy-L-proline inhibits N-nitrosomethylurea-induced breast tumor growth. cis-4-Hydroxy-L-proline improves lung compliance and reduces prostate weight. cis-4-Hydroxy-L-proline can be used in the study of hypoxic pulmonary hypertension .

Cat. No.	Product Name	Type

HY-40114

Boc-L-proline	Biochemical Assay Reagents
Boc-L-proline is an amino acid derivative. As an important intermediate in organic synthesis, Boc-L-proline can be used for peptide synthesis .

HY-W016042

N-Cbz-Hydroxy-L-proline	Biochemical Assay Reagents
N-Cbz-Hydroxy-L-proline is a chiral N-Cbz-protected amino acid derivative. N-Cbz-Hydroxy-L-proline is commonly used in the synthesis of polypeptides and pharmaceutical intermediates. N-Cbz-Hydroxy-L-proline undergoes decarboxylation under AlCl₃/HFIP conditions .

HY-167566

Poly-L-proline	Biochemical Assay Reagents
Poly-L-proline is a kind of biochemical reagent.

HY-137859

L-Proline 7-amido-4-methylcoumarin hydrobromide	Biochemical Assay Reagents
L-Proline 7-amido-4-methylcoumarin hydrobromide is a biochemical reagent.

HY-W014540

L-Proline tert-butyl ester hydrochloride tert-Butyl L-prolinate hydrochloride	Biochemical Assay Reagents
L-Proline tert-butyl ester hydrochloride (tert-Butyl L-prolinate hydrochloride) is a biologically active compound that has the activity of inhibiting cysteine and cathepsins, and is therefore widely used in the research and development of protease inhibitors. The characteristics of L-Proline tert-butyl ester hydrochloride make it of great significance in the field of biochemistry.

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-Y0252

*L-Proline* 5+ Cited Publications	Structural Classification Microorganisms Classification of Application Fields Other Diseases Amino acids Endogenous metabolite Disease Research Fields Source Classification	Endogenous Metabolite mTOR Apoptosis
L-Proline is one of the twenty amino acids used in living organisms as the building blocks of proteins.

HY-N0455

L-Arginine 20+ Cited Publications	Cardiovascular Disease Structural Classification Classification of Application Fields Amino acids Endogenous metabolite Disease Research Fields Source Classification Cancer	Environmental Pollutants Endogenous Metabolite NO Synthase
L-Arginine ((S)-(+)-Arginine) is the substrate for the endothelial nitric oxide synthase (eNOS) to generate NO. L-Arginine is transported into vascular smooth muscle cells by the cationic amino acid transporter family of proteins where it is metabolized to nitric oxide (NO), polyamines, or L-proline. L-Arginine is a potent vasodilator, and can be used to induce experimental acute pancreatitis .

HY-N0455A

L-Arginine hydrochloride Maximum Cited Publications 23 Publications Verification (S)-(+)-Arginine hydrochloride	Natural Products Classification of Application Fields Other Diseases Endogenous metabolite Disease Research Fields Source Classification	NO Synthase Endogenous Metabolite
L-Arginine ((S)-(+)-Arginine) is the substrate for the endothelial nitric oxide synthase (eNOS) to generate NO. L-Arginine is transported into vascular smooth muscle cells by the cationic amino acid transporter family of proteins where it is metabolized to nitric oxide (NO), polyamines, or L-proline. L-Arginine is a potent vasodilator, and can be used to induce experimental acute pancreatitis .

HY-Y0252R

L-Proline (Standard)	Structural Classification Microorganisms Amino acids Endogenous metabolite Source Classification	Reference Standards Endogenous Metabolite mTOR Apoptosis
L-Proline (Standard) is the analytical standard of L-Proline. This product is intended for research and analytical applications. L-Proline is one of the twenty amino acids used in living organisms as the building blocks of proteins.

HY-W016887

Glycyl-L-proline H-Gly-Pro-OH; Gly-Pro	Alkaloids Structural Classification Human Gut Microbiota Metabolites Pyrrole Alkaloids Classification of Application Fields Metabolic Disease Endogenous metabolite Disease Research Fields Source Classification	Endogenous Metabolite Apoptosis
Glycyl-L-proline (H-Gly-Pro-OH) is a dipeptide. Glycyl-L-proline can induce MCF-7 cells apoptosis. Glycyl-L-proline can enhance the inhibitory effect of the PRODH/POX knockout on collagen and DNA biosynthesis. Glycyl-L-proline can inhibit Gly-Sar and L-proline transport. Glycyl-L-proline can be used for the researches of cancer and metabolic disease, such as breast cancer .

HY-17490

Oxaceprol 1 Publications Verification N-Acetyl-L-hydroxyproline	Classification of Application Fields Ketones, Aldehydes, Acids Endogenous metabolite Inflammation/Immunology Disease Research Fields Source Classification	Amino Acid Derivatives
Oxaceprol (N-Acetyl-L-hydroxyproline), an orally active derivative of L-proline, possesses distinct anti-inflammatory activity. Oxaceprol is usually used for the research of osteoarthritis and rheumatoid arthritis .

HY-N0455R

L-Arginine (Standard)	Structural Classification Human Gut Microbiota Metabolites Microorganisms Amino acids Endogenous metabolite Source Classification	Reference Standards NO Synthase Endogenous Metabolite
L-Arginine (Standard) is the analytical standard of L-Arginine. This product is intended for research and analytical applications. L-Arginine ((S)-(+)-Arginine) is the substrate for the endothelial nitric oxide synthase (eNOS) to generate NO. L-Arginine is transported into vascular smooth muscle cells by the cationic amino acid transporter family of proteins where it is metabolized to nitric oxide (NO), polyamines, or L-proline. L-Arginine is a potent vasodilator, and can be used to induce experimental acute pancreatitis .

HY-21754

Hygric acid N-Methyl-L-proline	Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Rutaceae Other Diseases Plants Disease Research Fields Citrus reticulata Blanco Source Classification	Others
Hygric acid (N-Methyl-L-proline) is a proline analog that is found in bergamot, various citrus juices, and alfalfa seedlings .

HY-40136

cis-4-Hydroxy-L-proline	Microorganisms Classification of Application Fields Santalum album Linn. Ketones, Aldehydes, Acids Metabolic Disease Plants Endogenous metabolite Disease Research Fields Source Classification Santalaceae	Endogenous Metabolite
cis-4-Hydroxy-L-proline is an orally active proline analog and collagen production inhibitor. cis-4-Hydroxy-L-proline inhibits cell growth by preventing the deposition of triple helical collagen on the cell layer. cis-4-Hydroxy-L-proline inhibits N-nitrosomethylurea-induced breast tumor growth. cis-4-Hydroxy-L-proline improves lung compliance and reduces prostate weight. cis-4-Hydroxy-L-proline can be used in the study of hypoxic pulmonary hypertension .

HY-N2368A

Arecaidine hydrochloride 1 Publications Verification	Alkaloids Areca catechu L. Pyridine Alkaloids Palmae Plants Source Classification	GABA Receptor
Arecaidine hydrochloride, a pyridine alkaloid, is a potent GABA uptake inhibitor. Arecaidine hydrochloride is a substrate of H ⁺-coupled amino acid transporter 1 (PAT1, SLC36A1) and competitively inhibits L-proline uptake .

HY-W008129

H-D-cis-Hyp-OH	Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Metabolic Disease Endogenous metabolite Disease Research Fields Source Classification	Drug Intermediate Bacterial
H-D-cis-Hyp-OH is a proline derivative and also a substrate of cis-4-hydroxy-D-proline dehydrogenase from Sinorhizobium meliloti. H-D-cis-Hyp-OH serves as a starting material for the synthesis of conformationally constrained pyrrolidine PNA adenine monomers .

HY-W004114

N-Acetyl-L-proline	Alkaloids Pyrrole Alkaloids Classification of Application Fields Other Diseases Endogenous metabolite Disease Research Fields Source Classification	Amino Acid Derivatives Endogenous Metabolite
N-Acetyl-L-proline is aproline derivatives.

HY-W016887R

*Glycyl-L-proline* (Standard)** H-Gly-Pro-OH (Standard); Gly-Pro (Standard)	Alkaloids Structural Classification Human Gut Microbiota Metabolites Microorganisms Pyrrole Alkaloids Endogenous metabolite Source Classification	Reference Standards Endogenous Metabolite
H-Gly-Pro-OH (Standard) is the analytical standard of H-Gly-Pro-OH. This product is intended for research and analytical applications. H-Gly-Pro-OH is an end product of collagen metabolism that is further cleaved by prolidase.

HY-N2368AR

Arecaidine hydrochloride (Standard)	Alkaloids Structural Classification Areca catechu L. Pyridine Alkaloids Palmae Plants Source Classification	Reference Standards GABA Receptor
Arecaidine hydrochloride, a pyridine alkaloid, is a potent GABA uptake inhibitor. Arecaidine hydrochloride is a substrate of H+-coupled amino acid transporter 1 (PAT1, SLC36A1) and competitively inhibits L-proline uptake .

HY-40136R

*cis-4-Hydroxy-L-proline* (Standard)**	Structural Classification Microorganisms Santalum album Linn. Ketones, Aldehydes, Acids Plants Endogenous metabolite Source Classification Santalaceae	Reference Standards Endogenous Metabolite
cis-4-Hydroxy-L-proline (Standard) is the analytical standard of cis-4-Hydroxy-L-proline (HY-40136). This product is intended for research and analytical applications. cis-4-Hydroxy-L-proline is an orally active proline analog and collagen production inhibitor. cis-4-Hydroxy-L-proline inhibits cell growth by preventing the deposition of triple helical collagen on the cell layer. cis-4-Hydroxy-L-proline inhibits N-nitrosomethylurea-induced breast tumor growth. cis-4-Hydroxy-L-proline improves lung compliance and reduces prostate weight. cis-4-Hydroxy-L-proline can be used in the study of hypoxic pulmonary hypertension .

HY-17490R

Oxaceprol (Standard) N-Acetyl-L-hydroxyproline (Standard)	Structural Classification Ketones, Aldehydes, Acids Endogenous metabolite Source Classification	Amino Acid Derivatives Reference Standards
Oxaceprol (Standard) is the analytical standard of Oxaceprol. This product is intended for research and analytical applications. Oxaceprol (N-Acetyl-L-hydroxyproline), an orally active derivative of L-proline, possesses distinct anti-inflammatory activity. Oxaceprol is usually used for the research of osteoarthritis and rheumatoid arthritis .

HY-N0455AR

L-Arginine hydrochloride (Standard) (S)-(+)-Arginine hydrochloride (Standard)	Structural Classification Natural Products Endogenous metabolite Source Classification	Reference Standards NO Synthase Endogenous Metabolite
L-Arginine (hydrochloride) (Standard) is the analytical standard of L-Arginine (hydrochloride). This product is intended for research and analytical applications. L-Arginine ((S)-(+)-Arginine) is the substrate for the endothelial nitric oxide synthase (eNOS) to generate NO. L-Arginine is transported into vascular smooth muscle cells by the cationic amino acid transporter family of proteins where it is metabolized to nitric oxide (NO), polyamines, or L-proline. L-Arginine is a potent vasodilator, and can be used to induce experimental acute pancreatitis .

Cat. No.	Product Name	Chemical Structure

HY-Y0252S

L-Proline-13C5
L-Proline- ¹³C₅ is the ¹³C-labeled L-Proline. L-Proline is one of the twenty amino acids used in living organisms as the building blocks of proteins.

HY-Y0252S1

L-Proline-d3
L-Proline-d₃ is the deuterium labeled L-Proline. L-Proline is one of the twenty amino acids used in living organisms as the building blocks of proteins.

HY-Y0252S5

L-Proline-d7
L-Proline-d₇ is the deuterium labeled L-Proline. L-Proline is one of the twenty amino acids used in living organisms as the building blocks of proteins.

HY-Y0252S4

L-Proline-13C5,15N
L-Proline- ¹³C₅,1- ¹⁵N is the ¹³C- and ¹⁵N-labeled L-Proline. L-Proline is one of the twenty amino acids used in living organisms as the building blocks of proteins.

HY-Y0252S3

L-Proline-13C
L-Proline- ¹³C is the ¹³C-labeled L-Proline. L-Proline is one of the twenty amino acids used in living organisms as the building blocks of proteins.

HY-144250S

*Glycyl-L-proline-15N,d2 trifluoroacetate*
Glycyl-L-proline- ¹⁵N,d₂ (trifluoroacetate) is a ¹⁵N-labeled and deuterium labeled Glycyl-L-proline .

HY-Y0252S2

L-Proline-15N
L-Proline- ¹⁵N is the ¹⁵N-labeled L-Proline. L-Proline is one of the twenty amino acids used in living organisms as the building blocks of proteins .

HY-40136S

cis-4-Hydroxy-L-proline-d3

cis-4-Hydroxy-L-proline-d₃ is the deuterium labeled cis-4-Hydroxy-L-proline (HY-40136). cis-4-Hydroxy-L-proline is an orally active proline analog and collagen production inhibitor. cis-4-Hydroxy-L-proline inhibits cell growth by preventing the deposition of triple helical collagen on the cell layer. cis-4-Hydroxy-L-proline inhibits N-nitrosomethylurea-induced breast tumor growth. cis-4-Hydroxy-L-proline improves lung compliance and reduces prostate weight. cis-4-Hydroxy-L-proline can be used in the study of hypoxic pulmonary hypertension .

HY-Y0252S8

L-Proline-d4
L-Proline-d₄ is the deuterium labeled L-Proline (HY-Y0252). L-Proline is one of the twenty amino acids used in living organisms as the building blocks of proteins.

HY-17490S

Oxaceprol-d3
Oxaceprol-d₃ (N-Acetyl-L-hydroxyproline-d₃) is deuterium labeled Oxaceprol. Oxaceprol (N-Acetyl-L-hydroxyproline), an orally active derivative of L-proline, possesses distinct anti-inflammatory activity. Oxaceprol is usually used for the research of osteoarthritis and rheumatoid arthritis .

HY-W740245

Arecaidine-d5 hydrobromide
Arecaidine-d₅ hydrobromide is the deuterium labeled Arecaidine hydrobromide (HY-N2368B). Arecaidine hydrobromide, a pyridine alkaloid, is a potent GABA uptake inhibitor. Arecaidine hydrobromide is a substrate of H+-coupled amino acid transporter 1 (PAT1, SLC36A1) and competitively inhibits L-proline uptake .

HY-Y0252S7

L-Proline-15N,d7
L-Proline- ¹⁵N,d₇ is the deuterium and ¹⁵N labeled L-Proline . L-Proline is one of the twenty amino acids used in living organisms as the building blocks of proteins.

Cat. No.	Product Name		Classification

HY-142035

N-Propargylglycine 1 Publications Verification		Alkynes
N-Propargylglycine is a brain-penetrant and orally active PRODH inhibitor. N-Propargylglycine covalently modifies enzyme-bound FAD and active site lysine, causing enzyme structural distortion, protein decay, and irreversible inhibition of proline and 4-hydroxyproline catabolism. N-Propargylglycine induces UPRmt, upregulates mitochondrial chaperones and YME1L1, enhances mitochondrial proteostasis, blocks astrocytic L-proline consumption, and abolishes L-proline’s ATP-maintaining and viability-protective effects. N-Propargylglycine stimulates neural processes, increases brain proline, hydroxyproline, and sarcosine levels, partially normalizes Huntington’s disease whole brain transcriptomes. N-Propargylglycine reduces hyperoxaluria, prevents calcium oxalate stone formation, reduces kidney tubular damage, and restores weight and survival in Grhpr knockout mice. N-Propargylglycine can be used for the research of breast cancer, neurodegenerative disorders, Huntington’s disease, and primary hyperoxaluria type 2 .

Cat. No.	Product Name		Classification

HY-N0455

L-Arginine 20+ Cited Publications		Solubilizing Agents
L-Arginine ((S)-(+)-Arginine) is the substrate for the endothelial nitric oxide synthase (eNOS) to generate NO. L-Arginine is transported into vascular smooth muscle cells by the cationic amino acid transporter family of proteins where it is metabolized to nitric oxide (NO), polyamines, or L-proline. L-Arginine is a potent vasodilator, and can be used to induce experimental acute pancreatitis .

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