704-15-4
704-15-4
Chemical Structure
Glycyl-L-proline
Synonym(s): H-Gly-Pro-OH; Gly-Pro
- CAS No.: 704-15-4
- Formula:C7H12N2O3
- Molecular Weight:172.18
IUPAC Name: glycyl-L-proline
InChIKey: KZNQNBZMBZJQJO-YFKPBYRVSA-N
SMILES: NCC(N1CCC[C@H]1C(O)=O)=O
Biological Activity: Glycyl-L-proline (H-Gly-Pro-OH) is a dipeptide. Glycyl-L-proline can induce MCF-7 cells apoptosis. Glycyl-L-proline can enhance the inhibitory effect of the PRODH/POX knockout on collagen and DNA biosynthesis. Glycyl-L-proline can inhibit Gly-Sar and L-proline transport. Glycyl-L-proline can be used for the researches of cancer and metabolic disease, such as breast cancer[1][2][3].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Glycyl-L-proline | 99.88% | Glycyl-L-proline (H-Gly-Pro-OH) is a dipeptide. Glycyl-L-proline can induce MCF-7 cells apoptosis. Glycyl-L-proline can enhance the inhibitory effect of the PRODH/POX knockout on collagen and DNA biosynthesis. Glycyl-L-proline can inhibit Gly-Sar and L-proline transport. Glycyl-L-proline can be used for the researches of cancer and metabolic disease, such as breast cancer. | ||||||||||||||||||||
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Glycyl-L-proline (Standard) | 98.54% | H-Gly-Pro-OH (Standard) is the analytical standard of H-Gly-Pro-OH. This product is intended for research and analytical applications. H-Gly-Pro-OH is an end product of collagen metabolism that is further cleaved by prolidase. | ||||||||||||||||||||
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Glycyl-L-proline-15N,d2 trifluoroacetate | 98.86% | Glycyl-L-proline-15N,d2 (trifluoroacetate) is a 15N-labeled and deuterium labeled Glycyl-L-proline. | ||||||||||||||||||||
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References
- [1]. Zareba I, et al. Proline oxidase silencing induces proline-dependent pro-survival pathways in MCF-7 cells. Oncotarget. 2018;9(17):13748-13757. Published 2018 Feb 9. [Content Brief]
- [2]. von Linde T, et al. Rapid and Sensitive Quantification of Intracellular Glycyl-Sarcosine for Semi-High-Throughput Screening for Inhibitors of PEPT-1. Pharmaceutics. 2021;13(7):1019. Published 2021 Jul 3. [Content Brief]
- [3]. Boyd CA, et al. L-proline transport by brush border membrane vesicles prepared from human placenta. J Physiol. 1981;315:9-19. [Content Brief]
