6 Results for "

LPS binding protein

" in MedChemExpress (MCE) Product Catalog:
Products (6)

6 Results for "LPS binding protein" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-W251428
CAS No.: 383907-64-0
Synonyms: Egg PG
Phosphatidylglycerols (PG) is a selective inhibitor targeting the TLR4 accessory protein CD14/MD-2 complex, inhibiting LPS or virus (such as RSV)-mediated inflammatory signaling pathways through competitive binding. Phosphatidylglycerols directly bind to viral particles to block infection, inhibit COX-2 expression to reduce the release of inflammatory factors (IL-6, IL-8), and improve oxidative stress by regulating mitochondrial membrane phospholipid remodeling. Phosphatidylglycerols can be taken orally or by inhalation and can be used in the study of chronic inflammatory diseases (such as atherosclerosis) and respiratory viral infections (such as RSV) .
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Cat. No.: HY-113898
CAS No.: 104700-95-0
Ganoderic acid K is a triterpenoid compound. Ganoderic acid K can be isolated from Ganoderma lucidum. Ganoderic acid K inhibits ACE activity with an IC50 of 2.6×10 -5 M. Ganoderic acid K exhibits direct, high-affinity binding to recombinant MD2 protein, with a Kd value of 0.47 μM. It potently inhibits LPS-induced release of TNF-α and IL-6. It reduces cerebral infarction volume and ameliorates neurological dysfunction in mice with ischemic stroke in the tMCAO model. Ganoderic acid K can be used in studies related to hypertension and ischemic stroke .
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Cat. No.: HY-P11772
CAS No.: 324030-22-0
Target:  

Bacterial

Research Areas:  

Infection

LBP-14, a peptide, is a synthetic fragment of the LPS (HY-D1056) binding protein (LBP) and is a LPS antagonist. LBP-14 interacts with LPS via electrostatic contacts between arginine/lysine residues and LPS phosphate groups, and hydrophobic contacts between aromatic/aliphatic residues and LPS acyl chains, blocking LPS binding to LBP. LBP-14 moderately inhibits LPS-induced TNF-α formation. LBP-14 can be used for the research of gram-negative sepsis .
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Cat. No.: HY-P11772A
Target:  

Bacterial

Research Areas:  

Infection

LBP-14-NH2 (TFA) is a lipopolysaccharide (LPS)-binding protein (LBP) inhibitor. LBP-14-NH2 TFA interacts with LPS (HY-D1056) to form a complex and blocks the interaction between LBP and LPS. LBP-14-NH2 TFA can be used in studies related to Gram-negative bacterial sepsis .
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Cat. No.: HY-N19854
CAS No.: 2097442-40-3
Mariaterpenoside A is an inducible nitric oxide synthase (iNOS) inhibitor. Mariaterpenoside A interacts with the active cavity of iNOS protein via hydrogen bonds with specific residues of the binding site. Mariaterpenoside A suppresses NO release in LPS (HY-D1056)-induced murine microglial BV-2 cells. Mariaterpenoside A can be used for the research of neurodegenerative disease .
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Cat. No.: HY-W016183
CAS No.: 1806-29-7
Synonyms: o,o'-Biphenol
2,2'-Biphenol (o,o'-Biphenol) is an anti-inflammatory agent and the major non-protein-bound phenolic metabolite activated by rat bone marrow homogenate and hydrogen peroxide. 2,2'-Biphenol inhibits lipopolysaccharide (LPS) (HY-D1056)-induced COX-2 mRNA and protein expression. 2,2'-Biphenol suppresses the binding of AP-1 and NF-κB to their respective consensus sequences. 2,2'-Biphenol is applicable to research related to inflammation .
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