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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
14 Results for "
MBD2
" in MedChemExpress (MCE) Product Catalog:
Products (14)
14 Results for "MBD2" in MCE Product Catalog:
2
2 Cited Publications
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KCC-07 is a potent and brain-penetrant MBD2 (methyl-CpG-binding domain protein 2) inhibitor. KCC-07 prevents binding of MBD2 to methylated DNA and activates brain specific angiogenesis inhibitor 1 (BAI1) inducing anti-proliferative BAI1/p53/p21 signaling . KCC-07 is a TRACER (transcriptional regulation via active control of epigenetic reprogramming) that can stimulate ER transcriptional activity [2]. KCC-07 can be used for the stduy of breast cancer .
Cat. No.: HY-RS08182
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MBD2 Human Pre-designed siRNA Set A contains three designed siRNAs for MBD2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS24283
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Mbd2 Rat Pre-designed siRNA Set A contains three designed siRNAs for Mbd2 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS17814
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Mbd2 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Mbd2 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-179238
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CS-1-103 is a potent estrogen receptor (ER) TRACER (transcriptional regulation via active control of epigenetic reprogramming). CS-1-103 inhibits ER transcriptional activity with an EC50 of 0.36 μM by recruiting methyl-CpG binding domain protein 2 (MBD2), HDACs and the nucleosome remodeling and deacetylase (NuRD) complex. CS-1-103 can be used for breast and prostate cancer research .
Cat. No.: HY-128562
CAS No.: 315702-79-5
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CS-1-69 is an MBD2 ligand analog that does not bind to individual NuRD components MBD2 or HDAC1, but binds robustly to the assembled NuRD complex (MBD2, HDAC1, and MT1A) in a dose-responsive manner. CS-1-69 attenuates Transcriptional Repression via Active Chemical Epigenetic Reprogrammin (TRACER)-mediated strogen receptor (ER) inhibitory activity .
Cat. No.: HY-186233
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CS-1-174 is a biotin-modified probe derived from KCC-07 (HY-131031), with specific binding activity to enrich MBD2. CS-1-174 captures MBD2 in cell lysates via pull-down by binding streptavidin magnetic beads through its terminal biotin tag. CS-1-174 serves as a functional tool probe in the development of TRACER technology, and is used to verify the target binding ability of MBD2 in tumor cells .
Cat. No.: HY-RS03948
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DPEP2 Human Pre-designed siRNA Set A contains three designed siRNAs for DPEP2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS18658
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Dpep2 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Dpep2 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
