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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
38 Results for "
MST1
" in MedChemExpress (MCE) Product Catalog:
Products (38)
38 Results for "MST1" in MCE Product Catalog:
84
84 Publications Verification
Target:
Research Areas:
XMU-MP-1 is a reversible and selective MST1/2 inhibitor with IC50s of 71.1 and 38.1 nM, respectively [1].
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Research Areas:
Merestinib (LY2801653) is a potent, orally bioavailable c-Met inhibitor (Ki=2 nM) with anti-tumor activities. Merestinib (LY2801653) also has potent activity against MST1R (IC50=11 nM), FLT3 (IC50=7 nM), AXL (IC50=2 nM), MERTK (IC50=10 nM), TEK (IC50=63 nM), ROS1, DDR1/2 (IC50=0.1/7 nM) and MKNK1/2 (IC50=7 nM) [1] .
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6 Cited Publications
Synonyms: LY2801653 dihydrochloride
Research Areas:
Merestinib dihydrochloride (LY2801653 dihydrochloride) is a potent, orally bioavailable c-Met inhibitor (Ki=2 nM) with anti-tumor activities. Merestinib dihydrochloride also has potent activity against MST1R (IC50=11 nM), FLT3 (IC50=7 nM), AXL (IC50=2 nM), MERTK (IC50=10 nM), TEK (IC50=63 nM), ROS1, DDR1/2 (IC50=0.1/7 nM) and MKNK1/2 (IC50=7 nM) [1] .
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I3MT-3 (HMPSNE) is a potent, selective, and cell-membrane permeable inhibitor of 3-Mercaptopyruvate sulfurtransferase (3MST) (IC50=2.7 μM). I3MT-3 is inactive for other H2S/sulfane sulfur-producing enzymes.?I3MT-3 targets a persulfurated cysteine residue located in the active site of 3MST .
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2 Cited Publications
Target:
Research Areas:
SBP-3264 is a YAP activator and STK/MST inhibitor with IC50 values of 36 nM against STK3/MST2 and 24 nM against STK4/MST1. SBP-3264 modulates the Hippo signaling pathway. SBP-3264 can be used for the research of acute myeloid leukemia [1].
2
2 Cited Publications
Cat. No.: HY-P74742
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: STK4; Kinase Responsive To Stress 2; Serine/Threonine Kinase 4; Mammalian Sterile 20-Like 1; MST1; STE20-Like Kinase MST1; KRS2; Non-Specific Serine/Threonine Protein Kinase; YSK3; Hippo (Drosophila) Homolog; Mammalian STE20-Like Protein Kinase 1; Yeast S
Species:
Source:
1
1
1 Cited Publications
Cat. No.: HY-P701103
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: MST1; NF15S2; Prev. D3F15S2; Macrophage Stimulatory Protein; Prev. DNF15S2; Macrophage Stimulating 1 (Hepatocyte Growth Factor-Like); Prev. HGFL; Hepatocyte Growth Factor-Like Protein Homolog; MSP; Hepatocyte Growth Factor-Like; Hepatocyte Growth Factor-L
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IHMT-MST1-58 is a potent, selective mammalian and orally active STE20-like protein 1 kinase (MST1) inhibitor with IC50 value of 23 nM. IHMT-MST1-58 can be used for the research of Type 1/2 diabetes [1].
Cat. No.: HY-164595
CAS No.: 2414484-01-6
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IHMT-MST1-39 is an orally active inhibitor for MST kinase, with IC50 of 42, 109, 286, 159 nM for MST1, MST2, MST3, MST4. IHMT-MST1-39 activates the AMPK signaling pathway in liver cells, reduces apoptosis of pancreatic β-cells. IHMT-MST1-39 can be used for the studies of type 1 diabetes (T1D) and type 2 diabetes (T2D) [1].
Cat. No.: HY-157932A
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MR24 TFA, a G-5555 (HY-19635) derivative, is a mammalian STE20-like (MST) kinase inhibitor. MR24 TFA shows selectively to MST3/4 over MST1/2, with EC50 values of 57 and 583 nM, respectively. MR24 TFA induces G1 phase cell cycle arrest. MR24 TFA can be used for cancer research, such as breast, liver and lung cancers [1].
Cat. No.: HY-RS08729
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Research Areas:
MST1 Human Pre-designed siRNA Set A contains three designed siRNAs for MST1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS16671
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Research Areas:
Mst1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Mst1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS23106
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Research Areas:
Mst1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Mst1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P991185
Target:
Research Areas:
Cat. No.: HY-P1790
CAS No.: 143364-95-8
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Research Areas:
Cat. No.: HY-157932
CAS No.: 3056814-89-9
Target:
Research Areas:
MR24, a G-5555 (HY-19635) derivative, is a mammalian STE20-like (MST) kinase inhibitor. MR24 shows selectively to MST3/4 over MST1/2, with EC50 values of 57 and 583 nM, respectively. MR24 induces G1 phase cell cycle arrest. MR24 can be used for cancer research, such as breast, liver and lung cancers [1].
Cat. No.: HY-RS08730
Target:
Research Areas:
MST1R Human Pre-designed siRNA Set A contains three designed siRNAs for MST1R gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS18291
Target:
Research Areas:
Mst1r Mouse Pre-designed siRNA Set A contains three designed siRNAs for Mst1r gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P702744
Purity: ≥ 80%, as determined by reducing SDS-PAGE.
Synonyms: STK4; Kinase Responsive To Stress 2; Serine/Threonine Kinase 4; Mammalian Sterile 20-Like 1; MST1; STE20-Like Kinase MST1; KRS2; Non-Specific Serine/Threonine Protein Kinase; YSK3; Hippo (Drosophila) Homolog; Mammalian STE20-Like Protein Kinase 1; Yeast S
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
