8 Results for "

Matriptase-IN-2

" in MedChemExpress (MCE) Product Catalog:
Products (8)

8 Results for "Matriptase-IN-2" in MCE Product Catalog:

46
46 Cited Publications
Cat. No.: HY-13512
CAS No.: 59721-29-8
Purity:  99.94%
Synonyms: Camostat mesilate; FOY305; FOY-S980
Camostat mesylate (Camostat mesilate) is an orally active, synthetic serine protease inhibitor for chronic pancreatitis. Camostat mesylate, an inhibitor of TMPRSS2, shows antiviral activity against SARS-CoV-2. Camostat mesylate also inhibits the activity of prostasin, trypsin, and matriptase .
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Cat. No.: HY-W783268A
CAS No.: 1268874-09-4
Target:  

Ser/Thr Protease

Research Areas:  

Inflammation/Immunology

Matriptase-IN-2 is a secondary amide inhibitor of matriptase derived from sulfonylated 3-amidinophenylalanine, with a Ki value of 5 nM. Matriptase acts as a novel initiator of cartilage matrix degradation in osteoarthritis, and Matriptase-IN-2 inhibits matriptase-mediated cartilage degradation. Matriptase-IN-2 is applicable for the research of osteoarthritis .
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Cat. No.: HY-W783268
CAS No.: 1268874-08-3
Target:  

Ser/Thr Protease

Research Areas:  

Metabolic Disease

Matriptase-IN-2 free base is a matriptase inhibitor with a Ki of 5 nM. Matriptase-IN-2 has the potential for musculoskeletal system disorder research (WO2011023958A1; compound 432) .
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Cat. No.: HY-130136A
Target:  

Ser/Thr Protease

Research Areas:  

Others

TMPRSS6-IN-1 (TFA) is a potent inhibitor of TMPRSS6 (Matriptase-2), belonging to TTSPs (transmembrane serine protease). TMPRSS6, is a type II TTSP, the genetic reduction of which will improve symptoms of hemochromatosis and beta thalassemia in mice .
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Cat. No.: HY-13512R
CAS No.: 59721-29-8
Synonyms: Camostat mesilate (Standard); FOY305 (Standard); FOY-S980 (Standard)
Camostat (mesylate) (Standard) is the analytical standard of Camostat (mesylate). This product is intended for research and analytical applications. Camostat mesylate (Camostat mesilate) is an orally active, synthetic serine protease inhibitor for chronic pancreatitis. Camostat mesylate, an inhibitor of TMPRSS2, shows antiviral activity against SARS-CoV-2. Camostat mesylate also inhibits the activity of prostasin, trypsin, and matriptase .
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Cat. No.: HY-130136
CAS No.: 2088415-78-3
Target:  

Ser/Thr Protease

Research Areas:  

Others

TMPRSS6-IN-1 (compound 8) is a potent inhibitor of TMPRSS6 (Matriptase-2), belonging to TTSPs (transmembrane serine protease). TMPRSS6, is a type II TTSP, the genetic reduction of which will improve symptoms of hemochromatosis and beta thalassemia in mice .
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Cat. No.: HY-161902
CAS No.: 3033379-90-4
Research Areas:  

Infection

MI-1904 is the inhibitor for matriptase/TMPRSS2, that exhibits antiviral activity against influenza virus H1N1 and H9N2. MI-1904 blocks the cleavage of glycoproteins on the viral surface, prevents the virus from binding to host cell receptors, and thus inhibits the entry and replication of the virus .
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Cat. No.: HY-P992451
Synonyms: KY1066
RLYB331 (KY1066) is a is a monoclonal antibody targeting Matriptase-2 (TMPRSS6) . RLYB331 binds to the serine protease active site of matriptase-2, blocking protease activity to increase hepcidin expression. RLYB331 reduces iron overload, inhibits α-aggregates, reduces ROS, inhibits apoptosis, and enhances erythroid differentiation. RLYB331 ameliorates ineffective erythropoiesis in β-thalassemic mouse models. RLYB331 can be used for the research of β-thalassemia [2].
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