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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
14 Results for "
NOR 1
" in MedChemExpress (MCE) Product Catalog:
Products (14)
14 Results for "NOR 1" in MCE Product Catalog:
2
2 Cited Publications
Cat. No.: HY-N6641
CAS No.: 21516-68-7
Category:
Natural Products Microorganisms Pigments Plants Other Families Extract Disease Research Fields Inflammation/Immunology Food Research
Target:
Cat. No.: HY-W270810
CAS No.: 360778-55-8
Target:
Research Areas:
NR4A agonist-1, a fatty acid mimetic (FAM), is a potent NR4A agonist. NR4A agonist-1 exhibits high agonist potency on NR4A receptors Nurr1, Nur77, and NOR-1, with EC50s of 0.09 μM, 0.04 μM, and 0.15 μM, respectively .
Cat. No.: HY-N7041
Cat. No.: HY-N11009
CAS No.: 942612-74-0
Category:
Triterpenes Terpenoids Cucurbitaceae Extract Siraitia grosvenorii (Swingle) C. Jeffrey ex Lu et Z. Y. Zhang Plants
Target:
Cat. No.: HY-N7040
CAS No.: 2170761-38-1
Category:
Infection Triterpenes Terpenoids Cucurbitaceae Extract Siraitia grosvenorii (Swingle) C. Jeffrey ex Lu et Z. Y. Zhang Plants Disease Research Fields
Target:
Cat. No.: HY-15364
CAS No.: 130447-37-9
Target:
Research Areas:
19-nor-1α,25-Dihydroxyvitamin D3 is a vitamin D receptor (VDR) agonist with an EC50 of 4.8 nM. 19-nor-1α,25-Dihydroxyvitamin D3 binds to VDR and promotes gene transcription. 19-nor-1α,25-Dihydroxyvitamin D3 can be used in the research of diseases related to the vitamin D signaling pathway .
Cat. No.: HY-N8041
CAS No.: 88901-43-3
Category:
Infection Triterpenes Terpenoids Cucurbitaceae Extract Siraitia grosvenorii (Swingle) C. Jeffrey ex Lu et Z. Y. Zhang Plants Disease Research Fields
Target:
Cat. No.: HY-N6641R
CAS No.: 21516-68-7
Target:
Cat. No.: HY-N9752
CAS No.: 942615-25-0
Category:
Cucurbitaceae Extract Siraitia grosvenorii (Swingle) C. Jeffrey ex Lu et Z. Y. Zhang Plants Steroids
Target:
Cat. No.: HY-181588
Target:
Research Areas:
NR4A agonist-2 is a selective pan-NR4A agonist designed based on Vidofludimus (HY-14908), with a Kd of 0.10 μM against NR4A1, and EC50 values of 0.098 μM, 0.092 μM and 0.09 μM against Nur77, Nurr1, NOR-1, respectively. NR4A agonist-2 exhibits 47-fold selectivity over DHODH, and shows no cytotoxic activity at concentrations up to 10 μM. By binding to a specific surface pocket in the ligand-binding domain of Nurr1, NR4A agonist-2 inhibits the formation of Nurr1 homodimers, activates response elements such as NBRE, NurRE, DR5, and then potently induces the expression of neuroprotective genes including BDNF, SOD2, thereby exerting neuroprotective activity. NR4A agonist-2 can be used in the research of neurodegenerative diseases such as Parkinson's disease, dementia and multiple sclerosis .
Cat. No.: HY-N17638
CAS No.: 942612-72-8
Category:
Cucurbitaceae Extract Siraitia grosvenorii (Swingle) C. Jeffrey ex Lu et Z. Y. Zhang Plants Steroids
Target:
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
