19 Results for "

NPR1

" in MedChemExpress (MCE) Product Catalog:
Products (19)

19 Results for "NPR1" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-P703074
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: ANP-A; ANPa; Atrionatriuretic peptide receptor A; Guanylate cyclase A; Guanylate cyclase; GUC2A; NPRA
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Cat. No.: HY-P1419
CAS No.: 124833-45-0
AP 811 is a selective atrial natriuretic peptide clearance receptor (ANP-CR, NPR3) antagonist with a Ki of 0.48 nM. AP 811 displays >20000-fold selectivity for NPR3 over NPR1. AP 811 abolishes ANP-induced pump stimulation [1] .
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Cat. No.: HY-P990951
CAS No.: 2845128-05-2
Synonyms: REGN-5381
Vixticibart (REGN-5381) is a fully human IgG4 monoclonal antibody and NPR1 agonist that targets NPR1. Vixticibart stabilizes the receptor in an activated conformation by binding to the N-terminal domain of NPR1, and enhances the activity of endogenous ligands ANP and BNP without blocking ligand binding when these ligands are present. Vixticibart exerts vasodilatory and hypotensive effects by inducing cGMP production, preferentially dilating venous vessels to reduce systolic and venous pressure, but does not induce diuresis and may trigger a compensatory increase in heart rate. Vixticibart produces a synergistic hypotensive effect when combined with angiotensin-converting enzyme inhibitors or angiotensin receptor blockers, and is currently mainly used in research related to heart failure and hypertension [1] .
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Cat. No.: HY-153650
CAS No.: 1394592-04-1
Purity:  99.22%
Research Areas:  

Others

JS11 is an inhibitor for natriuretic polypeptide receptor 1 (Npr1) with an IC50 of 1.9 μM for hNpr1. JS11 ameliorates the pruritus in mouse models [1].
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Cat. No.: HY-RS09497
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Others

NPR1 Human Pre-designed siRNA Set A contains three designed siRNAs for NPR1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS25113
Research Areas:  

Others

Npr1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Npr1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-177062
CAS No.: 3055143-61-5
NPRA agonist-11 (Example 161) is an NPRA (NPR1) agonist, with AC50 values of 1.681 μM and 0.989 μM for humans and monkeys, respectively. NPRA agonist-11 can be used in the research of cardiovascular diseases and other disorders [1].
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Cat. No.: HY-RS18627
Research Areas:  

Others

Npr1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Npr1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-P990921
CAS No.: 2845128-03-0
Synonyms: REGN-9035
HY-P990921 is an NPR1-targeting half-IG G4 -κ/h-CH2-CH3 type human antibody [1].
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Cat. No.: HY-P991121
CAS No.: 2988795-75-9
Baloncibart is a human IgG4K antibody targeting NPR1. The corresponding isotype control is: Human IgG4 (S228P) kappa, Isotype Control (HY-P99003) [1].
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Cat. No.: HY-P1419A
Target:  

Endothelin Receptor

Research Areas:  

Cardiovascular Disease

AP 811 acetate is a selective atrial natriuretic peptide clearance receptor (ANP-CR, NPR3) antagonist with a Ki of 0.48 nM. AP 811 acetate displays >20000-fold selectivity for NPR3 over NPR1. AP 811 acetate abolishes ANP-induced pump stimulation [1] .
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Cat. No.: HY-P704143
Synonyms: Atrial natriuretic peptide receptor 1; NPR1; NPRA; GC-A; ANPRA; NPR-A
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Cat. No.: HY-P703923
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Atrial natriuretic peptide receptor 1;  NPR1;  NPRA;  GC-A;  ANPRA;  NPR-A
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Cat. No.: HY-P703698
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
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Cat. No.: HY-P703700
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
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Cat. No.: HY-P703701
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
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Cat. No.: HY-P703703
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
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Cat. No.: HY-P703704
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
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Cat. No.: HY-P703684
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: ANP-A; ANPR-A; NPR-A
Species:  
Rat
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