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Results for "

NS3

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Akt (5) Amyloid-β (1) Apoptosis (7) Aurora Kinase (4) Bacterial (7) Bcl-2 Family (1) BCRP (1) Casein Kinase (1) COX (2) Cytochrome P450 (2) Dengue Virus (18) DNA/RNA Synthesis (11) Drug Derivative (1) Drug Isomer (1) Drug Metabolite (1) Endogenous Metabolite (1) ERK (2) Filovirus (1) Flavivirus (21) Fluorescent Dye (1) Fungal (1) G-quadruplex (2) Glucocorticoid Receptor (2) Glucose-6-Phosphate Isomerase (GPI) (1) GLUT (4) HBV (1) HCV (46) HCV Protease (53) HIV (3) HSV (3) Indoleamine 2,3-Dioxygenase (IDO) (4) Influenza Virus (1) Isotope-Labeled Compounds (4) mAChR (4) mTOR (1) NF-κB (2) NO Synthase (1) Nuclear Factor of activated T Cells (NFAT) (1) P-glycoprotein (1) Parasite (4) PGE synthase (1) PI3K (1) Ras (1) Reactive Oxygen Species (ROS) (1) Reference Standards (12) SARS-CoV (26) Ser/Thr Protease (1) Small Interfering RNA (siRNA) (1) Src (2) STAT (1) Thrombin (1) Thyroid Hormone Receptor (1) Toll-like Receptor (TLR) (1) Virus Protease (35) γ-secretase (1)
By Research Areas:	Cancer (14) Infection (106) Inflammation/Immunology (13) Metabolic Disease (7) Neurological Disease (7)
Oligonucleotides:	Human Pre-designed siRNA Sets (1) siRNAs (1)

115

Inhibitors & Agonists

Screening Libraries

Fluorescent Dye

Biochemical Assay Reagents

Peptides

Natural
Products

Recombinant Proteins

Isotope-Labeled Compounds

Antibodies

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-17634

Glecaprevir 5+ Cited Publications ABT-493	HCV HCV Protease SARS-CoV	Infection
Glecaprevir is a novel *HCV NS3/4A protease* inhibitor, with IC₅₀ values ranging from 3.5 to 11.3 nM. Glecaprevir is also a SARS-CoV 3CL ^pro inhibitor with an IC₅₀ of 4.09 μM .

HY-14434

Asunaprevir 40+ Cited Publications BMS-650032	HCV HCV Protease SARS-CoV	Infection
Asunaprevir (BMS-650032) is a potent and orally bioavailable *hepatitis C virus (HCV) NS3* protease inhibitor, with IC₅₀** of 0.2 nM-3.5 nM . Asunaprevir inhibits SARS-CoV-2 3CL ^pro activity .

HY-10235

Telaprevir 40+ Cited Publications VX-950	HCV Protease HCV SARS-CoV	Infection
Telaprevir (VX-950) is a highly selective, reversible, and potent peptidomimetic inhibitor of the *HCV NS3-4A protease, the steady-state inhibitory constant (K_i) of Telaprevir is 7 nM against a genotype 1 (H strain) NS3* protease domain plus a NS4A cofactor peptide ^[3]. Telaprevir inhibits SARS-CoV-2 3CL ^pro activity .

HY-15298

Grazoprevir 25+ Cited Publications MK-5172	HCV Protease HCV SARS-CoV	Infection
Grazoprevir (MK-5172) is a selective inhibitor of Hepatitis C virus NS3/4a protease with broad activity across genotypes and resistant variants, with K_is of 0.01 nM (gt1b), 0.01 nM (gt1a), 0.08 nM (gt2a), 0.15 nM (gt2b), 0.90 nM (gt3a), respectively . Grazoprevir inhibits SARS-CoV-2 3CL ^pro activity ^[3].

HY-10241

Simeprevir Maximum Cited Publications 45 Publications Verification TMC435; TMC435350	HCV HCV Protease SARS-CoV DNA/RNA Synthesis	Infection
Simeprevir (TMC435; TMC435350) is an oral, potent and highly specific *hepatitis C virus (HCV) NS3/4A protease* inhibitor with a K_i of 0.36 nM. Simeprevir inhibits HCV replication with an EC₅₀ of 7.8 nM. Simeprevir also potently suppresses SARS-CoV-2 replication and synergizes with Remdesivir. Simeprevir inhibits the main protease (M ^pro) and the RNA-dependent RNA polymerase (RdRp) of SARS-CoV-2, and also modulates host immune responses .

HY-N0110

Palmatine chloride Maximum Cited Publications 9 Publications Verification	mAChR Indoleamine 2,3-Dioxygenase (IDO) Virus Protease Aurora Kinase Apoptosis Bacterial Parasite	Infection Neurological Disease Metabolic Disease Inflammation/Immunology Cancer
Palmatine chloride is an orally active and irreversible indoleamine 2,3-dioxygenase 1 (IDO-1) inhibitor with IC₅₀s of 3 μM and 157μM against HEK 293-hIDO-1 and rhIDO-1, respectively. Palmatine chloride can also inhibit West Nile virus (WNV) *NS2B-NS3* protease in an uncompetitive manner with an IC₅₀** of 96 μM. Palmatine chloride shows anti-cancer, anti-oxidation, anti-inflammatory, neuroprotection, antibacterial, anti-viral activities ^[3] .

HY-10237

Boceprevir 30+ Cited Publications EBP 520; SCH 503034	HCV Protease HCV SARS-CoV	Infection
Boceprevir (EBP 520) is a potent, highly selective, orally bioavailable *HCV NS3* protease inhibitor with a K_i of 14 nM in both enzyme assay and an EC₉₀** of 350 nM in cell-based replicon assay ^[3] . Boceprevir inhibits SARS-CoV-2 3CL ^pro activity .

HY-12594

Paritaprevir 10+ Cited Publications ABT-450; Veruprevir	HCV Protease HCV SARS-CoV	Infection
Paritaprevir (ABT-450) is a potent, orally active and antiviral *non-structural protein 3/4A (NS3/4A) protease* inhibitor with EC₅₀s of 1 and 0.21 nM against HCV 1a and 1b, respectively. Paritaprevir is also a SARS-CoV 3CL ^pro inhibitor with an IC₅₀ of 1.31 μM. Paritaprevir is metabolized primarily by cytochrome P450 (CYP) 3A. The plasma concentration and half-life of Paritaprevir can be enhanced by Ritonavir (a CYP450 inhibitor) ^[3] .

HY-19840

Voxilaprevir GS-9857	HCV Protease	Infection Cancer
Voxilaprevir (GS-9857) is a noncovalent, reversible inhibitor of *HCV NS3/4A protease* inhibitor (PI) with pangenotypic antiviral activity . Voxilaprevir inhibits genotype 1b and 3a wild-type NS3 proteases with K_i values of 0.038 nM and 0.066 nM, respectively . Voxilaprevir is an orally active direct-acting antiviral agent (DAA) and can be used for HCV infection research .

HY-153810

Mosnodenvir JNJ-1802	Virus Protease Flavivirus Dengue Virus	Infection
Mosnodenvir (JNJ-1802) is an orally active pan serotype dengue virus (DENV) inhibitor, with EC₅₀ values ranging from 0.057 to 11 nM for four dengue virus (DENV) serotypes. Mosnodenvir blocks viral replication by inhibiting the formation of complexes between two viral proteins, nonstructural protein 3 (NS3) and NS4B, thereby preventing the formation of new viral RNA. Mosnodenvir exhibits picomolar to nanomolar antiviral activity in vitro and has antiviral efficacy in mice and non-human primates .

HY-10238

Danoprevir 15+ Cited Publications ITMN-191; R7227; RO5190591; RG7227	HCV Protease HCV SARS-CoV	Infection
Danoprevir (ITMN-191) is an orally active NS3/4A protease inhibitor for hepatitis C virus (HCV) with an IC₅₀ of 0.29 nM and is selective for NS3/4A over a panel of 53 proteases (IC₅₀ higher than 10 μM). Danoprevir (ITMN-191) inhibits HCV genotypes 1a, 1b, 4, 5, and 6 (IC₅₀s=0.2-0.4 nM) as well as 2b and 3a (IC₅₀s=1.6, 3.5 nM) . Danoprevir is also a SARS-CoV 3CL ^pro inhibitor with an IC₅₀ of 0.05 μM ^[3].

HY-N0110A

Palmatine	mAChR Indoleamine 2,3-Dioxygenase (IDO) Virus Protease Aurora Kinase Apoptosis Bacterial Parasite	Infection Neurological Disease Metabolic Disease Inflammation/Immunology Cancer
Palmatine is an orally active and irreversible indoleamine 2,3-dioxygenase 1 (IDO-1) inhibitor with IC₅₀s of 3 μM and 157μM against HEK 293-hIDO-1 and rhIDO-1, respectively. Palmatine can also inhibit West Nile virus (WNV) *NS2B-NS3* protease in an uncompetitive manner with an IC₅₀** of 96 μM. Palmatine shows anti-cancer, anti-oxidation, anti-inflammatory, neuroprotection, antibacterial, anti-viral activities ^[3] .

HY-139602

(+)-JNJ-A07 2 Publications Verification	Flavivirus Dengue Virus Virus Protease	Infection
(+)-JNJ-A07 is a highly potent, orally active pan-serotype dengue virus inhibitor targeting the NS3-NS4B interaction. (+)-JNJ-A07 exerts nanomolar to picomolar activity against a panel of 21 clinical isolates. (+)-JNJ-A07 has a favourable pharmacokinetic profile that results in outstanding efficacy against dengue virus infection in mouse infection models .

HY-100604

JNJ-40418677	γ-secretase Amyloid-β	Neurological Disease
JNJ-40418677 is an orally active modulator of γ-secretase, can cross the blood-brain barrier. JNJ-40418677 inhibits Aβ42 and *NS2B-NS3* protease, with IC₅₀**s of 200 nM and 3.9 μM, respectively. JNJ-40418677 displays good biological tolerance, can be use for Alzheimer’s disease research ^[3].

HY-15298A

Grazoprevir potassium salt 25+ Cited Publications MK-5172 potassium salt	HCV HCV Protease SARS-CoV	Infection
Grazoprevir potassium salt (MK-5172 potassium salt) is a selective inhibitor of Hepatitis C virus NS3/4a protease with broad activity across genotypes and resistant variants, with K_is of 0.01 nM (gt1b), 0.01 nM (gt1a), 0.08 nM (gt2a), 0.15 nM (gt2b), 0.90 nM (gt3a), respectively . Grazoprevir potassium salt inhibits SARS-CoV-2 3CL ^pro activity ^[3].

HY-120897

NS-3-008 hydrochloride	Bcl-2 Family Apoptosis	Inflammation/Immunology
NS-3-008 hydrochloride is an orally active transcriptional inhibitor of G0/G1 switch 2 (G0s2) with an IC₅₀ of 2.25 μM. NS-3-008 hydrochloride can be used for chronic kidney disease .

HY-15176C

Pyridostatin trihydrochloride 30+ Cited Publications RR82 trihydrochloride	DNA/RNA Synthesis G-quadruplex Flavivirus Src Virus Protease	Cancer
Pyridostatin (RR82) trihydrochloride is a G-quadruplex (G4) inducer/stabilizer with a K_d of 490 nM. Pyridostatin trihydrochloride also acts as an inhibitor of Zika virus (ZIKV) *NS2B-NS3* protease, with an IC₅₀ of 11.0 μM. Pyridostatin trihydrochloride interacts with G-quadruplex structures, regulates the expression of SRC and SUB1, and induces replication- and transcription-dependent DNA damage, growth arrest, and genomic instability. Pyridostatin trihydrochloride exhibits antiproliferative and antiviral activities. Pyridostatin trihydrochloride can be used in studies related to breast cancer, cervical cancer, and Zika virus infection ^[3] .

HY-W540972

Primulin Primuline	Fluorescent Dye HCV Dengue Virus	Infection
Primulin is a versatile fluorescent dye and bioactive compound widely used in analytical, biological, botanical and virological studies. Primulin acts as a versatile stain that labels plant cell walls and differentiates live and dead spermatozoa via distinct fluorescence patterns. Primulin exhibits strong albumin‑binding capacity. Primulin acts as a retrograde axonal tracer in neurobiological investigations. Primulin and its derivatives inhibit HCV NS3, block dengue virus NS3-mediated ATP hydrolysis, and disrupt HCV replicase assembly ^[3].

HY-W129596

Policresulen	Virus Protease Dengue Virus	Infection Inflammation/Immunology
Policresulen is a competitive inhibitor for *DENV2 NS2B/NS3* protease with an IC₅₀** of 0.48 μg/mL. Policresulen can be used as a local hemostatic and antibacterial agent for research of cervical and vaginal inflammation, skin lesions, oral mucosa and gingival inflammation .

HY-10300

Narlaprevir 5 Publications Verification SCH 900518	HCV HCV Protease SARS-CoV	Infection
Narlaprevir (SCH 900518) is a selective and orally bioavailable NS3 protease inhibitor with a K_i value of 6 nM and an EC₉₀ value of 40 nM . Narlaprevir also inhibits the HCV nonstructural protein 3 serine protease . Narlaprevir is also a SARS-CoV 3CL ^pro inhibitor with an IC₅₀ of 2.3 μM ^[3].

HY-144644

*NS2B/NS3-IN-3*	Virus Protease Flavivirus	Infection
NS2B/NS3-IN-3 (Compd 66) is an inhibitor of Flavivirus NS2B-NS3 protease .

HY-144612

*NS2B/NS3-IN-2*	Flavivirus Dengue Virus Virus Protease	Infection
NS2B/NS3-IN-2 is a potent dengue virus (DENV) *NS2B/NS3* covalent inhibitor with an IC₅₀ of 6.0 nM and K_i of 0.66 µM. NS2B/NS3-IN-2 shows no cytotoxicity and markedly increases the cell survival rate .

HY-10242

Ciluprevir BILN 2061; BILN 2061ZW	HCV HCV Protease DNA/RNA Synthesis	Infection
Ciluprevir (BILN 2061; BILN 2061ZW) is an orally active macrocyclic peptide inhibitor of hepatitis C virus (HCV)NS3 protease, with an IC₅₀ of 3 nM. Ciluprevir has Kᵢ values of 0.66 nM and 0.30 nM against genotypes 1b and 1a, respectively. Ciluprevir inhibits HCV RNA replication with an EC₅₀ of 1.2 nM, and its EC50 values against genotypes 1b and 1a are 3 nM and 4 nM, respectively. Ciluprevir shows no significant inhibition against human leukocyte elastase and hepatic cathepsin B. Ciluprevir can be used for genotype 1 HCV infection ^[3].

HY-18563

4-Phenoxybenzylamine	HCV	Infection
4-Phenoxybenzylamine inhibits the function of the *NS3* protein by stabilizing an inactive conformation with an IC₅₀ of about 500 μM against FL NS3/4a.

HY-136797

BP13944	Dengue Virus	Infection
BP13944 is a potential small molecule inhibitor discovered by high-throughput screening. It can effectively inhibit the expression of dengue virus (DENV) replicons with an EC50 value of 1.03±0.09 μM. BP13944 can inhibit the replication or viral RNA synthesis of all four serotypes of DENV, but is ineffective against Japanese encephalitis virus. BP13944 may target the DENV NS3 protease, and the E66G amino acid substitution in the NS3 protease region will cause the virus to become resistant to BP13944. BP13944 has no obvious cytotoxicity. As there is currently no effective dengue vaccine and treatment, BP13944, as an effective small molecule inhibitor, may become a potential agent for the treatment of dengue in the future.

HY-N6935

Sennidin B	DNA/RNA Synthesis HCV Akt GLUT	Infection Metabolic Disease
Sennidin B, a stereoisomer isolated from the leaves of Cassia angustifolia, has lower activity than Sennidin A. Sennidin A inhibits *HCV NS3* helicase, with an IC₅₀** of 0.8 μM. Sennidin A induces phosphorylation of Akt and glucose transporter 4 (GLUT4) translocation. Sennidin A stimulates the glucose incorporation .

HY-15256

Faldaprevir BI 201335	HCV Protease	Infection
Faldaprevir (BI 201335) is a potent, orally active and selective noncovalent inhibitor of NS3/4A protease of HCV (hepatitis C virus) genotypes 1a and 1b, with K_i values of 2.6 and 2.0 nM, respectively. Faldaprevir inhibits HCV RNA replication, with EC₅₀ values of 6.5 and 3.1 nM, respectively. Faldaprevir has potent antiviral activity against chronic HCV infection .

HY-15298B

Grazoprevir hydrate 25+ Cited Publications MK-5172 hydrate	HCV HCV Protease SARS-CoV	Infection
Grazoprevir hydrate (MK-5172 hydrate) is a selective inhibitor of Hepatitis C virus NS3/4a protease with broad activity across genotypes and resistant variants, with K_is of 0.01 nM (gt1b), 0.01 nM (gt1a), 0.08 nM (gt2a), 0.15 nM (gt2b), 0.90 nM (gt3a), respectively . Grazoprevir hydrate inhibits SARS-CoV-2 3CL ^pro activity ^[3].

HY-N0110B

Palmatine hydroxide Maximum Cited Publications 9 Publications Verification	mAChR Indoleamine 2,3-Dioxygenase (IDO) Virus Protease Aurora Kinase Apoptosis Bacterial Parasite	Infection Neurological Disease Metabolic Disease Inflammation/Immunology Cancer
Palmatine hydroxide is an orally active and irreversible indoleamine 2,3-dioxygenase 1 (IDO-1) inhibitor with IC₅₀s of 3 μM and 157μM against HEK 293-hIDO-1 and rhIDO-1, respectively. Palmatine hydroxide can also inhibit West Nile virus (WNV) *NS2B-NS3* protease in an uncompetitive manner with an IC₅₀** of 96 μM. Palmatine hydroxide shows anti-cancer, anti-oxidation, anti-inflammatory, neuroprotection, antibacterial, anti-viral activities ^[3] .

HY-134910

SID-852843	Virus Protease	Infection
SID-852843 is a *WNV NS2B-NS3* proteinase** inhibitor. SID-852843 can inhibit WNV NS2B-NS3 proteinase activity with IC₅₀ value of 0.105 μM. SID-852843 can be used for the research of virus infection .

HY-10243

Vaniprevir MK-7009	HCV HCV Protease	Infection
Vaniprevir (MK-7009) is a non-covalent competitive inhibitor of the hepatitis C virus (HCV) NS3/4A protease.

HY-112254

ZINC03129319	Flavivirus Dengue Virus Virus Protease	Infection
ZINC03129319 is a dengue virus (DENV) *NS2B-NS3* protease inhibitor extracted from patent US20150141521A1, has inhibition constants (K_i1) of 92 μM and K_i3** of 20 μM.

HY-144644A

*NS2B/NS3-IN-3 hydrochloride*	Virus Protease Flavivirus	Infection
NS2B/NS3-IN-3 hydrochlorideis an inhibitor of *Flavivirus NS2B-NS3* protease** .

HY-163318

*NS2B/NS3-IN-8*	Virus Protease	Infection
NS2B/NS3-IN-8 (compound SM7) is a Zika virus NS2B-NS3 protease inhibitor .

HY-162485

DV-B-120	Dengue Virus Virus Protease	Infection
DV-B-120 is a competitive inhibitor for dengue virus (DENV) with IC₅₀s of 5.35, 7.39, 10.49 and 8.58 μM, for DENV-1, DENV-2, DENV-3 and DENV-4, respectively, by inhibiting *NS2B-NS3* protease**. DV-B-120 exhibits antiviral activity through inhibition of DENV replication .

HY-I0179

ITMN 4077	HCV Protease	Infection
ITMN 4077 is a macrocyclic inhibitor against Hepatitis C Virus (HCV) NS3 protease (EC₅₀: 2131 nM) .

HY-12946

BI 653048	Glucocorticoid Receptor Cytochrome P450 HCV Protease	Infection Inflammation/Immunology
BI 653048, a chemical probe, is a selective and orally active nonsteroidal glucocorticoid (GC) agonist with an IC₅₀ value of 55 nM . BI 653048 inhibits CP1A2, CYP2D6, CYP2C9, CYP2C19 and CYP3A4 isoforms’ activity and reduces affinity for the hERG ion channel (IC₅₀>30 μM) . BI 653048 (Compound 103) is also a *HCV NS3* protease** inhibitor that can reduce viral loads infected with the hepatitis C virus ^[3].

HY-173018

ML283	HCV Dengue Virus	Infection
ML283 is a *HCV NS3* helicase inhibitor (IC₅₀: 2.6 μM). ML283 also inhibits DenV ATPase (IC₅₀**: 4.0 μM) .

HY-P2502

*Hepatitis Virus C NS3* Protease Inhibitor 2**	HCV Protease HCV	Infection
Hepatitis Virus C NS3 Protease Inhibitor 2 is a product-based peptide inhibitor of *hepatitis C virus (HCV) NS3* protease, with a K_i** of 41 nM .

HY-P4035

HCV NS4A Protein (18-40) (JT strain)	HCV	Infection
HCV NS4A Protein (18-40) (JT strain) is an HCV NS4A peptide, which comprised residues 18 to 40 of the NS4A protein and is known to increase the catalytic efficiency of NS3 protease .

HY-P4039

Ac-EEVVAC-pNA	HCV Protease	Infection
Ac-EEVVAC-pNA is a chromogenic substrate for a continuous spectrophotometric assay of HCV NS3 protease. The sequence EEVVAC is derived from the 5A-5B cleavage junction of the HCV polyprotein .

HY-W033815

6-Chloroindole-2-carboxylic acid	HCV HCV Protease	Infection
6-Chloroindole-2-carboxylic acid (Compound 10g) is a derivative of 2-carboxyindole. 6-Chloroindole-2-carboxylic acid can bind to the hepatitis C virus NS3 protease/NS4A cofactor complex, and its K_D value for the *ns4a-ns3p* protein is 0.4 mM.

HY-179013

*NS2B/NS3-IN-9*	Virus Protease Flavivirus Dengue Virus	Infection
NS2B/NS3-IN-9 (Compound 73) is a broad-spectrum, non-competitive anti-Orthoflavivirus lipopeptide inhibitor targeting the *NS2B-NS3* protease. NS2B/NS3-IN-9 exhibits IC₅₀ values for Dengue virus DENV2 NS2B-NS3, West Nile virus WNV NS2B-NS3, and Zika virus ZIKV NS2B-NS3 of 2.4, 7.2, and 1.9 μM, respectively. NS2B/NS3-IN-9 also exhibits antiviral activity at the cellular level against DENV2, WNV, and ZIKV, with EC₅₀ values of 4.1, 4.9, and 5.0 μM, respectively. NS2B/NS3-IN-9 has no significant toxicity to cells. NS2B/NS3-IN-9 can be used for the study of anti-Orthoflavivirus .

HY-109571

HZ-1157	Flavivirus Dengue Virus HCV Protease	Infection Inflammation/Immunology
HZ-1157 inhibits *HCV NS3/4A protease* with an IC₅₀ of 1.0 μmol/L. HZ-1157 (4a) has a high dengue virus inhibitory activity (EC₅₀ = 0.15 μM) and is a relatively nontoxic (CC₅₀ > 10 μM) dengue antiviral agent .

HY-150600

*NS2B/NS3-IN-7*	Virus Protease Flavivirus	Infection
NS2B/NS3-IN-7 (compound 26) is a highly potent *Zika virus NS2B-NS3* protease inhibitor with a K_i** value of 2.33 nM. NS2B/NS3-IN-7 can reduce amounts of ZIKV-infected cells .

HY-12946A

BI 653048 phosphate	Glucocorticoid Receptor Cytochrome P450 HCV Protease	Infection Inflammation/Immunology
BI 653048 phosphate is a selective and orally active nonsteroidal glucocorticoid (GC) agonist with an IC₅₀ value of 55 nM . BI 653048 phosphate inhibits CP1A2, CYP2D6, CYP2C9, CYP2C19 and CYP3A4 isoforms’ activity and reduces affinity for the hERG ion channel (IC₅₀>30 μM) . BI 653048 phosphate is extracted from patent WO2005028501A1 (Compound 103), is also a *HCV NS3* protease** inhibitor that can reduce viral loads infected with the hepatitis C virus ^[3].

HY-162146

NS3-IN-1	Filovirus DNA/RNA Synthesis	Infection
NS3-IN-1 (compound 302) is a potent helicase (NS3) inhibitor. NS3-IN-1 shows an potent inhibitor for yellow fever helicase .

HY-14404

MK-1220	HBV HCV Protease	Infection
MK-1220 is a covalently reversible inhibitor of the hepatitis C virus (HCV) NS3/4A protease (NS3/4A protease) with a K_i of 0.02 nM. MK-1220 in cell models simulating viral replication exhibits EC₅₀s of 4 (with 10% fetal bovine serum) and 11 nM (50% normal human serum). MK-1220 can be used for the study of chronic hepatitis C virus infection .

HY-10235S

Telaprevir-d4 VX-950-d₄	Isotope-Labeled Compounds HCV Protease HCV SARS-CoV	Infection
Telaprevir-d₄ is the deuterium labeled Telaprevir. Telaprevir (VX-950) is a highly selective, reversible, and potent peptidomimetic inhibitor of the HCV NS3-4A protease, the steady-state inhibitory constant (Ki) of Telaprevir is 7 nM against a genotype 1 (H strain) NS3 protease domain plus a NS4A cofactor peptide ^[3]. Telaprevir inhibits SARS-CoV-2 3CLpro activity .

HY-N6936

Sennidin A	DNA/RNA Synthesis HCV Akt GLUT	Infection
Sennidin A, isolated from the leaves of Cassia angustifolia, inhibits *HCV NS3* helicase, with an IC₅₀** of 0.8 μM. Sennidin A induces phosphorylation of Akt and glucose transporter 4 (GLUT4) translocation. Sennidin A stimulates the glucose incorporation .

Cat. No.	Product Name

HY-L073

Anti-Hepatitis C Virus Compound Library

391 compounds

Hepatitis C virus (HCV) is a hepatotropic enveloped positive- strand RNA virus (family Flaviviridae) that infects the parenchymal cells of the liver. HCV infection is a significant public health burden. Globally, an estimated 71 million people have chronic hepatitis C virus infection. A significant number of those who are chronically infected will develop cirrhosis or liver cancer. To date, there is no vaccine against HCV, and combination pegylated alpha interferon (pIFN-) and ribavirin, the main standard-of-care treatment for HCV, is effective in only a subset of patients and is associated with a wide spectrum of toxic side effects and complications. More recently, new therapeutic approaches that target essential components of the HCV life cycle have been developed, including direct-acting antiviral (DAA) that specifically block a viral enzyme or functional protein and host-targeted agents (HTA) that block interactions between host proteins and viral components that are essential to the viral life cycle. However, the genetic diversity of HCV viruses and the stage of liver disease (i.e., cirrhosis) are revealing themselves as obstacles for effective, pan-genotypic treatments. There still exists a need for the discovery and development of new HCV inhibitors. In particular, since the future of HCV therapy will likely consist of a cocktail approach using multiple inhibitors that target different steps of infection, new antivirals targeting all steps of the viral infection cycle.

MCE offers a unique collection of 391 compounds with identified and potential anti-HCV activity. MCE Anti- Hepatitis C Virus Compound Library is a useful tool for discovery new anti-HCV drugs and other anti-infection research.

Cat. No.	Product Name	Type

HY-W540972

Primulin

Primuline

Biochemical Assay Reagents

Primulin is a versatile fluorescent dye and bioactive compound widely used in analytical, biological, botanical and virological studies. Primulin acts as a versatile stain that labels plant cell walls and differentiates live and dead spermatozoa via distinct fluorescence patterns. Primulin exhibits strong albumin‑binding capacity. Primulin acts as a retrograde axonal tracer in neurobiological investigations. Primulin and its derivatives inhibit HCV NS3, block dengue virus NS3-mediated ATP hydrolysis, and disrupt HCV replicase assembly ^[3].

Cat. No.	Product Name	Target	Research Area

HY-P1633

Protegrin-1 PG1	Bacterial ERK COX NF-κB Apoptosis NO Synthase Dengue Virus	Infection Inflammation/Immunology
Protegrin-1 is an orally active antibacterial peptide. Protegrin-1 activates ERK, COX2, NFκB, inhibits Apoptosis, and NO production. Protegrin-1 has antibacterial activity against S. aureus, E. faecium, E. coli, P. aeruginosa and K. Pneumoniae, with MBC values between 10 and 20 µM. Protegrin-1 has antiviral activity against dengue NS2B-NS3. Protegrin-1 has anti-inflammatory activity. Protegrin-1 is used in the study of inflammatory diseases and infections ^[3] .

HY-P1684

Peptide P60 1 Publications Verification FOXP3 inhibitor P60	NF-κB Nuclear Factor of activated T Cells (NFAT)	Infection Inflammation/Immunology Cancer
Peptide P60 is a *FOXP3* inhibitor. Peptide P60 reduces the nuclear translocation of *FOXP3* and impairs *FOXP3*-mediated inhibition of NF-κB and NFAT activity. Peptide P60 inhibits the immunosuppressive activity of regulatory T cells and restores the proliferation and activation of effector T cells. Peptide P60 induces lymphoproliferative autoimmune syndrome in neonatal ICR mice and reduces the number of CD4 ⁺CD25 ⁺Foxp3 ⁺ T cells in the spleen. Peptide P60 enhances the efficacy of AH1 (HY-P4193) peptide vaccine and recombinant adenovirus-based HCV NS3 vaccine in BALB/c mice, including protective effects against CT26 tumor implantation. Peptide P60 can be used in studies related to tumor immunity, viral infection and lymphoproliferative autoimmune syndrome .

HY-P4209

Boc-GRR-AMC	Peptides	Others
Boc-GRR-AMC is a tri-peptide Substrate. Boc-GRR-AMC can be used for a fluorogenic West Nile virus (WNV) substrate, profiling the substrate specificity for the NS2B-NS3 proteases or determining the pH optimum of LdMC activity .

HY-P2502

*Hepatitis Virus C NS3* Protease Inhibitor 2**	HCV Protease HCV	Infection
Hepatitis Virus C NS3 Protease Inhibitor 2 is a product-based peptide inhibitor of *hepatitis C virus (HCV) NS3* protease, with a K_i** of 41 nM .

HY-P4035

HCV NS4A Protein (18-40) (JT strain)	HCV	Infection
HCV NS4A Protein (18-40) (JT strain) is an HCV NS4A peptide, which comprised residues 18 to 40 of the NS4A protein and is known to increase the catalytic efficiency of NS3 protease .

HY-P4039

Ac-EEVVAC-pNA	HCV Protease	Infection
Ac-EEVVAC-pNA is a chromogenic substrate for a continuous spectrophotometric assay of HCV NS3 protease. The sequence EEVVAC is derived from the 5A-5B cleavage junction of the HCV polyprotein .

HY-P5510

Ac-Asp-Glu-Asp(EDANS)-Glu-Glu-Abu-ψ-(COO)Ala-Ser-Lys(DABCYL)-NH2 HCV NS3 protease substrate	Peptides	Others
Ac-Asp-Glu-Asp(EDANS)-Glu-Glu-Abu-ψ-(COO)Ala-Ser-Lys(DABCYL)-NH2 (HCV NS3 protease substrate) is a biological active peptide. (This peptide is a HCV protease substrate incorporating an ester bond between residues P1 and P1. Due to ready transesterification of the scissile bond to the acyl-enzyme intermediate, this substrate shows very high kcat/Km values, enabling detection of activity with subnanomolar nonstructural protein 3 (NS3 protease) concentrations. It is widely used for the continuous assay of NS3 protease activity. Substrate cleavage is proportional to the enzyme concentration with a detection limit for NS3 between 1 nM and 250 pM.

HY-P10657

Ac-DEMEEC-OH	HCV HCV Protease	Infection
Ac-DEMEEC-OH is a *HCV NS3* protease** competitive inhibitor (K_i: 0.6 µM) .

HY-P10608

KK4A peptide	HCV	Infection
KK4A peptide is a small peptide derived from nonstructural protein 4A (NS4A) of hepatitis C virus (HCV) that significantly increases the catalytic efficiency of NS3 protease. The KK4A peptide may be used to gain insights into the function and mechanism of the HCV NS3 protease, thereby advancing research into HCV infection .

HY-P5312

Abz-Gly-Leu-Lys-Arg-Gly-Gly-3-(NO2)Tyr	Virus Protease	Infection
Abz-Nle-Lys-Arg-Arg-Ser-3-(NO2)Tyr is a *WNV NS2B-NS3* protease** substrate. Abz-Nle-Lys-Arg-Arg-Ser-3-(NO2)Tyr is used for WNV NS2B-NS3 protease substrate peptide selective inhibitor development .

HY-P2435

Bz-Nle-Lys-Arg-Arg-AMC	Peptides	Others
Bz-Nle-Lys-Arg-Arg-AMC can be used for protease activity assay. In 0.1mL Tris-HCl buffer (50 mM, pH 7.8), Bz-Nle-Lys-Arg-Arg-AMC was hydrolyzed, and the release rate of AMC was observed .

HY-P4209A

Boc-GRR-AMC TFA	Virus Protease	Others
Boc-GRR-AMC (TFA) is a tri-peptide Substrate. Boc-GRR-AMC can be used for a fluorogenic West Nile virus (WNV) substrate, profiling the substrate specificity for the NS2B-NS3 proteases or determining the pH optimum of LdMC activity .

HY-P4038

Hepatitis C Virus S5A/5B	HCV Protease	Infection
Hepatitis C Virus S5A/5B is a synthetic peptide substrate. Hepatitis C Virus S5A/5B mimics the NS5A/5B junction of the nonstructural protein (NS), served as the substrate for the study of HCV NS3 protease activity .

HY-P10668

Ac-EVKKQR-pNA	Dengue Virus Flavivirus	Infection
Ac-EVKKQR-pNA is a competitive chromogenic para-nitroanilide substrate corresponding to the P6-P1 segment amino-terminal to the *NS2B-NS3* cleavage site but with a more reactive, hydrolytically cleavable, para-nitroanilide at the P1’ position. Ac-EVKKQR-pNA is promising for research of dengue 2 virus and flavivirus virus infection .

HY-P5312A

Abz-Gly-Leu-Lys-Arg-Gly-Gly-3-(NO2)Tyr acetate	Virus Protease	Infection
Abz-Gly-Leu-Lys-Arg-Gly-Gly-3-(NO2)Tyr acetate is the acetate salt form of Abz-Gly-Leu-Lys-Arg-Gly-Gly-3-(NO2)Tyr. Abz-Gly-Leu-Lys-Arg-Gly-Gly-3-(NO2)Tyr acetate is the substrate for *WNV NS2B NS3* protease**, which is utilized for the development of WNV protease substrate peptide selective inhibitor .

HY-P11420

2A/2B Dengue protease substrate	Dengue Virus	Infection
2A/2B Dengue protease substrate (Ac-RTSKKR-pNA) is a peptide substrate for Dengue NS2B-NS3 protease. 2A/2B Dengue protease substrate is used for Dengue NS2B-NS3 protease substrate peptide selective inhibitor development .

HY-P5642A

Retrocyclin-101 TFA RC-101 TFA	HIV SARS-CoV Influenza Virus Flavivirus HSV Bacterial Fungal Toll-like Receptor (TLR) Ser/Thr Protease	Infection Inflammation/Immunology
Retrocyclin-101 (RC-101) TFA is an artificially synthesized, cyclic-structured θ-defensin, a broad-spectrum agent with antimicrobial (covering viruses, bacteria, and fungi) activity and anti-inflammatory activity. Retrocyclin-101 TFA can inhibit the serine protease activity of ZIKV NS2B-NS3, with an IC₅₀ of 7.20 μM. Retrocyclin-101 TFA has significant inhibitory activity against HIV, SARS-CoV-2, flaviviruses, influenza viruses, HSV-1/2, Staphylococcus aureus, etc. Retrocyclin-101 TFA inhibits the signal transduction mediated by TLR4 and TLR2, reducing the expression of pro-inflammatory cytokines ^[3] .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N0110

Palmatine chloride Maximum Cited Publications 9 Publications Verification	Alkaloids Phellodendron amurense Rupr. Classification of Application Fields Rutaceae Plants Isoquinoline Alkaloids Disease Research Fields Cancer	mAChR Indoleamine 2,3-Dioxygenase (IDO) Virus Protease Aurora Kinase Apoptosis Bacterial Parasite
Palmatine chloride is an orally active and irreversible indoleamine 2,3-dioxygenase 1 (IDO-1) inhibitor with IC₅₀s of 3 μM and 157μM against HEK 293-hIDO-1 and rhIDO-1, respectively. Palmatine chloride can also inhibit West Nile virus (WNV) *NS2B-NS3* protease in an uncompetitive manner with an IC₅₀** of 96 μM. Palmatine chloride shows anti-cancer, anti-oxidation, anti-inflammatory, neuroprotection, antibacterial, anti-viral activities ^[3] .

HY-N1992

Theaflavin 3,3'-digallate Maximum Cited Publications 9 Publications Verification TF-3; ZP10	Infection Flavonoids Classification of Application Fields Flavanols Phenols Polyphenols Camellia sinensis (L.) O. Ktze. Plants Disease Research Fields Source Classification Theaceae	Virus Protease HSV HIV Flavivirus
Theaflavin 3,3'-digallate (TF-3) is a potent Zika virus (ZIKV) protease inhibitor with an IC₅₀ of 2.3 μM. Theaflavin 3,3'-digallat directly binds to ZIKVpro (K_d=8.86 μM) and inhibits ZIKV replication. Theaflavin 3,3'-digallat inhibits the activity of gp41 and NS2B-3 protease and has antiviral activity against HSV and HIV-1 . Theaflavin 3,3'-digallate, the typical pigment in black tea, is a potent antitumor agent .

HY-N0110A

Palmatine	Alkaloids Phellodendron amurense Rupr. Classification of Application Fields Rutaceae Plants Isoquinoline Alkaloids Inflammation/Immunology Disease Research Fields Source Classification	mAChR Indoleamine 2,3-Dioxygenase (IDO) Virus Protease Aurora Kinase Apoptosis Bacterial Parasite
Palmatine is an orally active and irreversible indoleamine 2,3-dioxygenase 1 (IDO-1) inhibitor with IC₅₀s of 3 μM and 157μM against HEK 293-hIDO-1 and rhIDO-1, respectively. Palmatine can also inhibit West Nile virus (WNV) *NS2B-NS3* protease in an uncompetitive manner with an IC₅₀** of 96 μM. Palmatine shows anti-cancer, anti-oxidation, anti-inflammatory, neuroprotection, antibacterial, anti-viral activities ^[3] .

HY-N12586

Pheophytin a	Suaeda vermiculata Forssk. ex J.F.Gmel. Structural Classification Alkaloids Other Alkaloids Amaranthaceae Plants Source Classification	ERK Reactive Oxygen Species (ROS) COX PGE synthase STAT HCV HCV Protease
Pheophytin a is a multi-target inhibitor, anticancer agent, antioxidant and antiviral agent. Pheophytin a directly binds to and inhibits *HCV-NS3/4A* protease (IC₅₀=0.89 μM) to block viral replication. Pheophytin a also scavenges free radicals, reduces ferric ions, and exhibits cytotoxic activity against breast cancer cells. Pheophytin a effectively inhibits LPS-induced production of nitric oxide, prostaglandin E2, NOS2 and COX-2, as well as various pro-inflammatory cytokines, by downregulating the transcription levels of inflammatory mediators and blocking the ERK1/2 and STAT-1 pathways. In a low nerve growth factor environment, Pheophytin a also enhances ERK1/2 phosphorylation and synergistically promotes neurite outgrowth through MAPK pathway. Pheophytin a can be used to investigate the pathogenic mechanisms of diseases including chronic hepatitis C, sepsis, breast cancer and Alzheimer's disease ^[3] .

HY-N6935

Sennidin B	Structural Classification Classification of Application Fields Metabolic Disease Plants Infection other families Leguminosae Ketones, Aldehydes, Acids Phenols Polyphenols Cassia angustifolia Disease Research Fields Source Classification	DNA/RNA Synthesis HCV Akt GLUT
Sennidin B, a stereoisomer isolated from the leaves of Cassia angustifolia, has lower activity than Sennidin A. Sennidin A inhibits *HCV NS3* helicase, with an IC₅₀** of 0.8 μM. Sennidin A induces phosphorylation of Akt and glucose transporter 4 (GLUT4) translocation. Sennidin A stimulates the glucose incorporation .

HY-N0110B

Palmatine hydroxide Maximum Cited Publications 9 Publications Verification	Alkaloids Phellodendron amurense Rupr. Other Alkaloids Rutaceae Plants Source Classification	mAChR Indoleamine 2,3-Dioxygenase (IDO) Virus Protease Aurora Kinase Apoptosis Bacterial Parasite
Palmatine hydroxide is an orally active and irreversible indoleamine 2,3-dioxygenase 1 (IDO-1) inhibitor with IC₅₀s of 3 μM and 157μM against HEK 293-hIDO-1 and rhIDO-1, respectively. Palmatine hydroxide can also inhibit West Nile virus (WNV) *NS2B-NS3* protease in an uncompetitive manner with an IC₅₀** of 96 μM. Palmatine hydroxide shows anti-cancer, anti-oxidation, anti-inflammatory, neuroprotection, antibacterial, anti-viral activities ^[3] .

HY-N6841

Rhodiolin 1 Publications Verification	Flavonols Flavonoids Classification of Application Fields Rhodiola rosea Linn. Crassulaceae Other Diseases Phenols Polyphenols Plants Disease Research Fields Source Classification	Glucose-6-Phosphate Isomerase (GPI) Casein Kinase Virus Protease Flavivirus PI3K Akt mTOR Apoptosis
Rhodiolin, a flavonoid, is an orally active glucose 6-phosphate isomerase (GPI) inhibitor. Rhodiolin inhibits papillary thyroid cancer (PTC) by targeting glycolysis enzyme glucose 6-phosphate isomerase GPI and suppressing *PI3K/AKT/mTOR* phosphorylation and induce apoptosis. Rhodiolin as a *NS2B-NS3* protease inhibitor can disrupt dengue viral replication. Rhodiolin is also a potential candidate for developing anticancer strategies inhibiting CK1ε kinase. Rhodiolin can be used for the study of anti-tumor and anti-viral ^[3].

HY-N6936

Sennidin A	Infection Structural Classification other families Classification of Application Fields Ketones, Aldehydes, Acids Phenols Polyphenols Plants Disease Research Fields Source Classification	DNA/RNA Synthesis HCV Akt GLUT
Sennidin A, isolated from the leaves of Cassia angustifolia, inhibits *HCV NS3* helicase, with an IC₅₀** of 0.8 μM. Sennidin A induces phosphorylation of Akt and glucose transporter 4 (GLUT4) translocation. Sennidin A stimulates the glucose incorporation .

HY-N0110R

Palmatine chloride (Standard)	Structural Classification Alkaloids Phellodendron amurense Rupr. Classification of Application Fields Rutaceae Plants Isoquinoline Alkaloids Disease Research Fields Source Classification Cancer	Apoptosis Virus Protease Indoleamine 2,3-Dioxygenase (IDO) Parasite Bacterial Aurora Kinase mAChR Reference Standards
Palmatine (chloride) (Standard) is the analytical standard of Palmatine (chloride). This product is intended for research and analytical applications. Palmatine chloride is an orally active and irreversible indoleamine 2,3-dioxygenase 1 (IDO-1) inhibitor with IC₅₀s of 3 μM and 157μM against HEK 293-hIDO-1 and rhIDO-1, respectively. Palmatine chloride can also inhibit West Nile virus (WNV) *NS2B-NS3* protease in an uncompetitive manner with an IC₅₀** of 96 μM. Palmatine chloride shows anti-cancer, anti-oxidation, anti-inflammatory, neuroprotection, antibacterial, anti-viral activities ^[3] .

HY-N8520

Variculanol	Microorganisms Terpenoids Sesquiterpenes Source Classification	Bacterial
Variculanol is an antimicrobial, anticancer and anti-HCV NS3/4A Protease agent which can be extracted from marine fungus Aspergillus versicolor .

HY-N6936R

Sennidin A (Standard)	other families Ketones, Aldehydes, Acids Phenols Polyphenols Plants Source Classification	Reference Standards HCV Akt GLUT
Sennidin A (Standard) is the analytical standard of Sennidin A. This product is intended for research and analytical applications. Sennidin A, isolated from the leaves of Cassia angustifolia, inhibits HCV NS3 helicase, with an IC50 of 0.8 μM. Sennidin A induces phosphorylation of Akt and glucose transporter 4 (GLUT4) translocation. Sennidin A stimulates the glucose incorporation .

HY-N1992R

Theaflavin 3,3'-digallate (Standard) TF-3 (Standard); ZP10 (Standard)	Structural Classification Flavonoids Flavanols Phenols Polyphenols Camellia sinensis (L.) O. Ktze. Plants Source Classification Theaceae	Reference Standards Virus Protease HSV HIV Flavivirus
Theaflavin 3,3'-digallate (Standard) is the analytical standard of Theaflavin 3,3'-digallate. This product is intended for research and analytical applications. Theaflavin 3,3'-digallate (TF-3) is a potent Zika virus (ZIKV) protease inhibitor with an IC₅₀ of 2.3 μM. Theaflavin 3,3'-digallat directly binds to ZIKVpro (Kd=8.86 μM) and inhibits ZIKV replication. Theaflavin 3,3'-digallat inhibits the activity of gp41 and NS2B-3 protease and has antiviral activity against HSV and HIV-1 . Theaflavin 3,3'-digallate, the typical pigment in black tea, is a potent antitumor agent .

HY-N6935R

Sennidin B (Standard)	other families Leguminosae Ketones, Aldehydes, Acids Phenols Polyphenols Cassia angustifolia Plants Source Classification	Reference Standards HCV Akt GLUT
Sennidin B (Standard) is the analytical standard of Sennidin B. This product is intended for research and analytical applications. Sennidin B, a stereoisomer isolated from the leaves of Cassia angustifolia, has lower activity than Sennidin A. Sennidin A inhibits HCV NS3 helicase, with an IC50 of 0.8 μM. Sennidin A induces phosphorylation of Akt and glucose transporter 4 (GLUT4) translocation. Sennidin A stimulates the glucose incorporation .

HY-N12407

Peridinin	Structural Classification Natural Products Classification of Application Fields Ketones, Aldehydes, Acids Marine natural products Other marine organisms Pigments Source Classification Food Research	Dengue Virus
Peridinin is a hydroxylated carotenoid ketone that exhibits inhibitory activity against DENV NS2B/NS3 protease and all dengue virus serotypes (DENV-1, DENV-2, *DENV-3, DENV-4*). Peridinin inhibits dengue virus production and reduces viral titers. Peridinin is applicable to research related to dengue virus infection .

Cat. No.	Product Name	Chemical Structure

HY-10235S

Telaprevir-d4
Telaprevir-d₄ is the deuterium labeled Telaprevir. Telaprevir (VX-950) is a highly selective, reversible, and potent peptidomimetic inhibitor of the HCV NS3-4A protease, the steady-state inhibitory constant (Ki) of Telaprevir is 7 nM against a genotype 1 (H strain) NS3 protease domain plus a NS4A cofactor peptide ^[3]. Telaprevir inhibits SARS-CoV-2 3CLpro activity .

HY-10241S

Simeprevir-13C,d3

Simeprevir- ¹³C,d₃ is the ¹³C- and deuterium labeled Simeprevir. Simeprevir is an oral, potent and highly specific hepatitis C virus (HCV) NS3/4A protease inhibitor with a K_i of 0.36 nM. Simeprevir inhibits HCV replication with an EC₅₀ of 7.8 nM. Simeprevir also potently suppresses SARS-CoV-2 replication and synergizes with Remdesivir. Simeprevir inhibits the main protease (Mpro) and the RNA-dependent RNA polymerase (RdRp) of SARS-CoV-2, and also modulates host immune responses .

HY-131905S

BMS-986144
BMS-986144 is a third-generation, pan-genotype (GT) NS3/4A protease inhibitor. BMS-986144 inhibits HCV replicon with EC₅₀s of 2.3, 0.7, 1.0, 12, 8.0, and 5.8 nM for GT-1a, GT-1b, GT-2a, GT-3a, 1a R155X, and 1b D168V, respectively. BMS-986144 has the potential for the research of HCV infection .

HY-10237S

Boceprevir-d9
Boceprevir-d₉ is the deuterium labeled Boceprevir. Boceprevir (EBP 520) is a potent, highly selective, orally bioavailable HCV NS3 protease inhibitor with a K_i of 14 nM in both enzyme assay and an EC₉₀ of 350 nM in cell-based replicon assay ^[3] . Boceprevir inhibits SARS-CoV-2 3CLpro activity .

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HY-P86935

	KRAS Antibody (YA6628) c Ki ras2 antibody; c Kirsten ras protein antibody; c-K-ras antibody; c-Ki-ras antibody; Cellular c Ki ras2 proto oncogene antibody; Cellular traNSforming proto oncogene antibody; CFC2 antibody; cK Ras antibody; GTPase KRas antibody; K RAS p21 protein antibody; c Ki ras2 antibody; c Kirsten ras protein antibody; c-K-ras antibody; c-Ki-ras antibody; Cellular c Ki ras2 proto oncogene antibody; Cellular traNSforming proto oncogene antibody; CFC2 antibody; cK Ras antibody; GTPase KRas antibody; K RAS p21 protein antibody; K RAS2A antibody; K RAS2B antibody; K RAS4A antibody; K RAS4B antibody; K-Ras 2 antibody; KI RAS antibody; Ki-Ras antibody; KIRSTEN MURINE SARCOMA VIRUS 2 antibody; Kirsten rat sarcoma 2 viral (v Ki ras2) oncogene homolog antibody; Kirsten rat sarcoma viral oncogene homolog antibody; KRAS antibody; KRAS proto oncogene, GTPase antibody; KRAS1 antibody; KRAS2 antibody; N-terminally processed antibody; NS antibody; NS3 antibody; Oncogene KRAS2 antibody; p21ras antibody; PR310 c K ras oncogene antibody; PR310 cK ras oncogene antibody; RALD antibody; RASK_HUMAN antibody; RASK2 antibody; TraNSforming protein p21 antibody; v Ki ras2 Kirsten rat sarcoma 2 viral oncogene homolog antibody; v Ki ras2 Kirsten rat sarcoma viral oncogene homolog antibody;	WB, IHC-P	Human, Mouse, Rat
	KRAS Antibody (YA6628) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to KRAS.

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Species:	Human (29) Virus (1)
Tag:	His (28) Avi (27) TAT (1) GST (1)
Source:	HEK293 (27) E. coli (3)

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