18 Results for "

Notoginsenoside A

" in MedChemExpress (MCE) Product Catalog:
Products (18)

18 Results for "Notoginsenoside A" in MCE Product Catalog:

4
Notoginsenoside R1
Notoginsenoside R1
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4 Cited Publications
Cat. No.: HY-N0615
CAS No.: 80418-24-2
Synonyms: Sanchinoside R1; Sanqi glucoside R1
Category:  

Triterpenes Panax notoginseng (Burkill) F. H. Chen ex C. H. Chow Terpenoids Other Diseases Plants Disease Research Fields Araliaceae

Target:  

Amyloid-β Apoptosis

Notoginsenoside R1 (Sanchinoside R1), a saponin, is isolated from P. notoginseng. Notoginsenoside R1 exhibits anti-oxidation, anti-inflammatory, anti-angiogenic, and anti-apoptosis activities. Notoginsenoside R1 provides cardioprotection against ischemia/reperfusion (I/R) injury. Notoginsenoside R1 also provides neuroprotection in H2O2-induced oxidative damage in PC12 cells .
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Notoginsenoside R2
Notoginsenoside R2
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1 Cited Publications
Cat. No.: HY-N0909
CAS No.: 80418-25-3
Synonyms: 20(S)-Notoginsenoside R2; Ginsenoside Ng-R2
Category:  

Triterpenes Panax notoginseng (Burkill) F. H. Chen ex C. H. Chow Neurological Disease Terpenoids Plants Disease Research Fields Araliaceae

Target:  

Apoptosis MEK ERK Reactive Oxygen Species (ROS) Caspase COX β-catenin Src MDM-2/p53 JAK STAT

Notoginsenoside R2 (20(S)-Notoginsenoside R2; Ginsenoside Ng-R2) is an orally active notoginsenoside . Notoginsenoside R2 activates P90RSK and Nrf2 via the MEK1/2-ERK1/2 pathway to inhibit 6-OHDA-induced apoptotic damage in nerve cells. Notoginsenoside R2 upregulates SOX8/β-catenin by reducing miR-27a, thereby suppressing Aβ25-35-induced neuronal apoptosis and inflammatory responses . Notoginsenoside R2 alleviates lipid accumulation and mitochondrial dysfunction in diabetic nephropathy by inhibiting c-Src. Notoginsenoside R2 alleviates hepatic fibrosis by inducing hepatic stellate cell senescence and inhibiting the inflammatory microenvironment via JAK/STAT3 suppression . Notoginsenoside R2 can be used in research related to Parkinson's disease, Alzheimer's disease, diabetic nephropathy and hepatic fibrosis .
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Notoginsenoside Ft1
Notoginsenoside Ft1
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1 Cited Publications
Cat. No.: HY-N0910
CAS No.: 155683-00-4
Category:  

Triterpenes Panax notoginseng (Burkill) F. H. Chen ex C. H. Chow Terpenoids Other Diseases Plants Disease Research Fields Araliaceae

Target:  

PI3K mTOR Akt Apoptosis p38 MAPK ERK Transmembrane Glycoprotein Glutathione Reductase (GR) Estrogen Receptor/ERR Calcium Channel Ferroptosis G protein-coupled Bile Acid Receptor 1 FXR

Notoginsenoside Ft1 is an orally active bioactive saponin. Notoginsenoside Ft1 inhibits the PI3K/AKT/mTOR signaling pathway, activates the p38 MAPK and ERK1/2 signaling pathways, and increases the proportion of CD8 + T cells, thereby inducing apoptosis and lysosomal cell death in various cancer cells, and promoting angiogenesis. Notoginsenoside Ft1 causes vasodilation by activating glucocorticoid receptors (GR) and estrogen receptor beta (ERβ) in endothelial cells. Notoginsenoside Ft1 increases intracellular Ca 2+ accumulation, reduces cAMP levels by activating a signaling network mediated through P2Y12 receptors, and promotes platelet aggregation, thereby exerting a procoagulant effect. Notoginsenoside Ft1 inhibits ferroptosis (ferroptosis) in renal tubular epithelial cells by activating the TGR5 receptor, thereby demonstrating a renal protective effect. Notoginsenoside Ft1 acts as a TGR5 agonist and an FXR antagonist to combat obesity and insulin resistance .
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Notoginsenoside Fe
Notoginsenoside Fe
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Cat. No.: HY-N0046
CAS No.: 88105-29-7
Synonyms: Notoginseng triterpenes; Ginsenoside Mb
Category:  

Triterpenes Panax notoginseng (Burkill) F. H. Chen ex C. H. Chow Terpenoids Other Diseases Plants Disease Research Fields Araliaceae

Target:  

Apoptosis Src

Notoginsenoside Fe (Notoginseng triterpenes; Ginsenoside Mb) is a saponin with anti-obesity and anti-neuroblastoma activities. Notoginsenoside Fe can be isolated from leaves of Panax notoginseng. Notoginsenoside Fe specifically activates paraventricular nucleus neurons in the hypothalamus, effectively reducing body weight, improving fasting blood glucose and protecting liver function by decreasing food intake, increasing resting metabolic rate and enhancing energy expenditure. Notoginsenoside Fe also inhibits the c-Src signaling pathway, blocks the proliferation and viability of human neuroblastoma cells, while improving mitochondrial dysfunction and alleviating apoptosis. Notoginsenoside Fe can be used in studies related to diet-induced obesity and neuroblastoma .
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Notoginsenoside Fc
Notoginsenoside Fc
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Cat. No.: HY-N2531
CAS No.: 88122-52-5
Category:  

Cardiovascular Disease Triterpenes Panax notoginseng (Burkill) F. H. Chen ex C. H. Chow Terpenoids Plants Disease Research Fields Araliaceae

Target:  

Autophagy

Notoginsenoside Fc, a protopanaxadiol- (PPD-) type saponin isolated from the leaves of Panax notoginseng, effectively counteracts platelet aggregation. Notoginsenoside Fc can accelerate reendothelialization following vascular injury in diabetic rats by promoting autophagy .
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Notoginsenoside R4
Notoginsenoside R4
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Cat. No.: HY-N10336
CAS No.: 87741-77-3
Category:  

Panax ginseng C. A. Meyer Triterpenes Terpenoids Plants Araliaceae

Target:  

VEGFR STAT Akt Ras

Notoginsenoside R4 is a ginsenoside that can be isolated from ginseng roots. In the molecular docking results, Notoginsenoside R4 can target STAT3, AKT1, HRAS, VEGFA and CASP3 .
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Notoginsenoside Fa
Notoginsenoside Fa
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Cat. No.: HY-N2530
CAS No.: 88100-04-3
Category:  

Triterpenes Panax notoginseng (Burkill) F. H. Chen ex C. H. Chow Terpenoids Plants Araliaceae

Target:  

Others

Notoginsenoside Fa, a protopanaxadiol (ppd)-type saponin isolated from P. notoginseng, could possibly activate and recover the function of degenerated brain .
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Notoginsenoside R3
Notoginsenoside R3
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Cat. No.: HY-N10151
CAS No.: 87741-76-2
Category:  

Cardiovascular Disease Triterpenes Panax notoginseng (Burkill) F. H. Chen ex C. H. Chow Terpenoids Plants Disease Research Fields Araliaceae

Target:  

Others

Notoginsenoside R3 is an active principle components of P. notoginseng. Notoginsenoside R3 act as a signaling molecule that is associated with various physiological effects. P. notoginseng and its components are used as traditional Chinese medicine for cardiovascular disease .
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Notoginsenoside FP2
Notoginsenoside FP2
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Cat. No.: HY-N4305
CAS No.: 1004988-75-3
Category:  

Cardiovascular Disease Triterpenes Panax notoginseng (Burkill) F. H. Chen ex C. H. Chow Terpenoids Plants Disease Research Fields Araliaceae

Target:  

Others

Notoginsenoside FP2, a dammarane-Type Bisdesmoside isolated from the Fruit Pedicels of Panax notoginseng, has potential to treat cardiovascular disease .
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Notoginsenoside D
Notoginsenoside D
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Cat. No.: HY-N16751
CAS No.: 193895-50-0
Category:  

Triterpenes Panax notoginseng (Burkill) F. H. Chen ex C. H. Chow Tetracyclic Triterpenoids Terpenoids Plants Araliaceae

Target:  

Others

Notoginsenoside D is a dammarane-type triterpene oligoglycoside. Notoginsenoside D can be isolated from the dried roots of Panax notoginseng (BURK.) F. H. CHEN. Notoginsenoside D can be used in the research of liver injury .
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Notoginsenoside S
Notoginsenoside S
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Cat. No.: HY-N5019
CAS No.: 575446-95-6
Category:  

Triterpenes Panax notoginseng (Burkill) F. H. Chen ex C. H. Chow Terpenoids Other Diseases Plants Disease Research Fields Araliaceae

Target:  

Others

Notoginsenoside S is a compound isolated from Panax notoginseng.
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20(R)-Notoginsenoside R2
20(R)-Notoginsenoside R2
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Cat. No.: HY-N2049
CAS No.: 948046-15-9
Category:  

Triterpenes Panax notoginseng (Burkill) F. H. Chen ex C. H. Chow Terpenoids Plants Araliaceae

Target:  

Others

20(R)-Notoginsenoside R2 is an isolated notoginsenoside from Panax notoginseng .
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Notoginsenoside R2 (Standard)
Notoginsenoside R2 (Standard)
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Cat. No.: HY-N0909R
CAS No.: 80418-25-3
Synonyms: 20(S)-Notoginsenoside R2 (Standard); Ginsenoside Ng-R2 (Standard)
Category:  

Triterpenes Panax notoginseng (Burkill) F. H. Chen ex C. H. Chow Terpenoids Plants Araliaceae

Target:  

Reference Standards Apoptosis

Notoginsenoside R2 (Standard) is the analytical standard of Notoginsenoside R2. This product is intended for research and analytical applications.
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Notoginsenoside R1 (Standard)
Notoginsenoside R1 (Standard)
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Cat. No.: HY-N0615R
CAS No.: 80418-24-2
Synonyms: Sanchinoside R1 (Standard); Sanqi glucoside R1 (Standard)
Category:  

Triterpenes Panax notoginseng (Burkill) F. H. Chen ex C. H. Chow Terpenoids Plants Araliaceae

Target:  

Reference Standards Amyloid-β Apoptosis

Notoginsenoside R1 (Standard) is the analytical standard of Notoginsenoside R1. This product is intended for research and analytical applications. Notoginsenoside R1 (Sanchinoside R1), a saponin, is isolated from P. notoginseng. Notoginsenoside R1 exhibits anti-oxidation, anti-inflammatory, anti-angiogenic, and anti-apoptosis activities. Notoginsenoside R1 provides cardioprotection against ischemia/reperfusion (I/R) injury. Notoginsenoside R1 also provides neuroprotection in H2O2-induced oxidative damage in PC12 cells .
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Notoginsenoside Fa (Standard)
Notoginsenoside Fa (Standard)
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Cat. No.: HY-N2530R
CAS No.: 88100-04-3
Category:  

Triterpenes Panax notoginseng (Burkill) F. H. Chen ex C. H. Chow Terpenoids Plants Araliaceae

Target:  

Reference Standards Others

Notoginsenoside Fa (Standard) is the analytical standard of Notoginsenoside Fa. This product is intended for research and analytical applications. Notoginsenoside Fa, a protopanaxadiol (ppd)-type saponin isolated from P. notoginseng, could possibly activate and recover the function of degenerated brain .
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Notoginsenoside T5
Notoginsenoside T5
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Cat. No.: HY-N6581
CAS No.: 769932-34-5
Category:  

Cardiovascular Disease Triterpenes Panax notoginseng (Burkill) F. H. Chen ex C. H. Chow Terpenoids Plants Disease Research Fields Araliaceae

Target:  

Others

Notoginsenoside T5 is a dammarane 61 glycoside. Notoginsenoside T5 is isolated from the acidic deglycosylation of saponins from the roots of P. 62 notoginseng .
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Notoginsenoside A
Notoginsenoside A
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Cat. No.: HY-N18198
CAS No.: 193895-21-5
Category:  

Tetracyclic Triterpenoids Panax quinquefolium Terpenoids Plants Araliaceae

Target:  

Others

Notoginsenoside A (Compound 6) is a dammarane-type triterpene oligoglycoside found in the roots of Panax quinquefolium L. .
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Panax notoginseng extract
Panax notoginseng extract
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Cat. No.: HY-N18670
CAS No.: 94279-78-4
Category:  

Extract

Target:  

Others

Panax notoginseng extract is derived from the stems and leaves of Panax notoginseng, a plant belonging to the Araliaceae family. Its main active ingredient is notoginsenoside (PNS), among which notoginsenoside Rb1, notoginsenoside Rg1, and notoginsenoside R1 are present in high amounts and can be used for skin conditioning in functional cosmetics.
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