Cat. No.: HY-N10336

Notoginsenoside R4

Customer Review

Based on 1 Customer Validation

Notoginsenoside R4 is a ginsenoside that can be isolated from ginseng roots. In the molecular docking results, Notoginsenoside R4 can target STAT3, AKT1, HRAS, VEGFA and CASP3.

For research use only. We do not sell to patients.

Purity: 99.34%
CAS No.: 87741-77-3
Formula: C₅₉H₁₀₀O₂₇
Molecular Weight:1241.41

Storage:

Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month

Notoginsenoside R4 Chemical Structure

CAS No.: 87741-77-3

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

Notoginsenoside R4 is a ginsenoside that can be isolated from ginseng roots. In the molecular docking results, Notoginsenoside R4 can target STAT3, AKT1, HRAS, VEGFA and CASP3^[1]^[2].

All VEGFR Isoforms :

All Ras Isoforms :

All Akt Isoforms :

All STAT Isoforms :

Chemical Information

CAS No. 87741-77-3
Appearance Solid
Molecular Weight 1241.41
Formula C₅₉H₁₀₀O₂₇
Color White to off-white
SMILES

C[C@@]([C@@]([C@@]1([H])[C@@]2([H])[C@@](CC/C=C(C)/C)(C)O[C@@H]([C@@H]([C@H]3O)O)O[C@@H]([C@H]3O)CO[C@@H]([C@@H]([C@H]4O)O)O[C@@H]([C@H]4O)CO[C@H](OC[C@H]5O)[C@@H]([C@H]5O)O)(CC2)C)(CC[C@@]6([H])C7(C)C)[C@@](C[C@H]1O)([H])[C@]6(CC[C@@H]7O[C@H](O[C@@H]8CO)[C@@H]([C@H]([C@@H]8O)O)O[C@@H]([C@@H]([C@H]9O)O)O[C@@H]([C@H]9O)CO)C
Structure Classification
- Terpenoids
- Triterpenes
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

H₂O : 5 mg/mL (4.03 mM; Need ultrasonic and warming)

View the Complete Stock Solution Preparation Table

Preparing Stock Solutions

View the Complete Stock Solution Preparation Table

Concentration Solvent Mass

1 mg

5 mg

10 mg

Concentration

Solvent

Mass

1 mM

0.8055 mL

4.0277 mL

8.0554 mL

5 mM

---

10 mM

---

Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.

Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

Molarity Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Molecular Weight Molecular Weight

Dilution Calculator

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Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (284 KB)
SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Zhao Y Y, et al. Systemic mechanism of Panax noteginseng saponins in antiaging based on network pharmacology combined with experimental validation[J]. Ibrain, 2024.

[2]. MATSUURA, et al. Further studies on dammarane-saponins of ginseng roots.. CHEMICAL & PHARMACEUTICAL BULLETIN, 32(3), 1188–1192.

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Complete Stock Solution Preparation Table

Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg
H₂O	1 mM	0.8055 mL	4.0277 mL	8.0554 mL	20.1384 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Notoginsenoside R4

GPCR/G Protein Compound Library

Immunology/Inflammation Compound Library

JAK/STAT Compound Library

MAPK Compound Library

PI3K/Akt/mTOR Compound Library

Protein Tyrosine Kinase Compound Library

Stem Cell Signaling Compound Library

Natural Product Library

Autophagy Compound Library

Anti-Aging Compound Library

Glycoside Compound Library

Oxygen Sensing Compound Library

Ferroptosis Compound Library

Medicine Food Homology Compound Library

Terpenoids Library

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Glutamine Metabolism Compound Library

Traditional Chinese Medicine Active Compound Library

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Membrane Protein-targeted Compound Library

Membrane Receptor-targeted Compound Library

Multi-Target Compound Library

Bioactive Compound Library Max

Natural Product Library Plus

Natural Product and Natural Product-Like Compound Library

Bioactive Compound Library

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Mass Spectrometry Natural Product Library

All VEGFR Isoforms

All Ras Isoforms

All Akt Isoforms

All STAT Isoforms