16 Results for "

OCN

" in MedChemExpress (MCE) Product Catalog:
Products (16)

16 Results for "OCN" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-N2120
CAS No.: 88509-91-5
Dichotomitin is an isoflavonoid compound isolated from the rhizomes of Belamcanda chinensis. Dichotomitin exhibits antioxidant activity, alleviates oxidative stress, reduces intracellular reactive oxygen species (ROS) levels, and upregulates the expression of SOD1, SOD2 and CAT. Dichotomitin increases ALP activity while upregulating the expression of RUNX2, OPN and OCN. Dichotomitin has antitussive activity and helps improve symptoms of upper respiratory tract infections .
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Cat. No.: HY-Y0332B
CAS No.: 7778-77-0
Potassium dihydrogen phosphate, AR,99.5% is a potassium salt. Potassium dihydrogen phosphate, AR,99.5% activates NF-κB. Potassium dihydrogen phosphate, AR,99.5% upregulates the expression of dental/osteogenic markers (OCN, DSP/DSPP, OSX, RUNX2, ALP) and enhances the mineralization capacity of human periodontal ligament stem cells. Potassium dihydrogen phosphate, AR,99.5% promotes the proliferation of human periodontal ligament stem cells in logarithmic growth phase. Potassium dihydrogen phosphate, AR,99.5% promotes the growth of somatic embryos of Dendrobium Sonia, increases leaf number, leaf length and fresh weight of tissue-cultured seedlings. Potassium dihydrogen phosphate, AR,99.5% is applicable to periodontal disease-related research .
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Cat. No.: HY-Y0332K
CAS No.: 7778-77-0
Synonyms: Potassium phosphate monobasic, for cell culture
Potassium dihydrogen phosphate, for cell culture (Potassium phosphate monobasic, for cell culture) is a cell culture reagent. Potassium dihydrogen phosphate, for cell culture activates NF-κB. Potassium dihydrogen phosphate, for cell culture upregulates the expression of dental/osteogenic markers (OCN, DSP/DSPP, OSX, RUNX2, ALP) and enhances the mineralization capacity of human periodontal ligament stem cells. Potassium dihydrogen phosphate, for cell culture promotes the proliferation of human periodontal ligament stem cells in logarithmic growth phase. Potassium dihydrogen phosphate, for cell culture promotes the growth of somatic embryos of Dendrobium Sonia, increases leaf number, leaf length and fresh weight of tissue-cultured seedlings. Potassium dihydrogen phosphate, for cell culture is applicable to periodontal disease-related research .
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Cat. No.: HY-145584
CAS No.: 2055357-64-5
Purity:  99.54%
Synonyms: JPI-547/OCN-201
Target:  

PARP Wnt β-catenin

Research Areas:  

Neurological Disease Cancer

Nesuparib (JPI-547) is the orally active inhibitor for PARP 1/2 and Tankyrase 1/2 that inhibits tankyrases 1, tankyrases 2, and PARP 1 with IC50s of 5, 1 and 2 nM, respectively. Nesuparib exhibits antitumor activity and can be used in research of advanced solid tumor .
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Cat. No.: HY-N4119
CAS No.: 13241-32-2
Neoeriocitrin is a Naringin (HY-N0153) analogue found in Drynaria Rhizome. Neoeriocitrin induces cells proliferation, differentiation, up-regulates type I collagen, osteocalcin, and key osteogenic markers, and increases ALP activity. Neoeriocitrin increases expression of Runx2, COL I, OCN and Beclin1. Neoeriocitrin inhibits phosphorylation of P38 mitogen-activated protein kinase, reduces acetylcholinesterase (AChE) activity, and increases choline acetyltransferase (ChAT) activity. Neoeriocitrin reduces apoptosis and induces autophagy. Neoeriocitrin can be used for the researches of osteoporosis and Alzheimer's disease .
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Cat. No.: HY-P5832
CAS No.: 836606-84-9
Target:  

TGF-beta/Smad RUNX

Research Areas:  

Metabolic Disease

BMP2-derived peptide is an osteogenic inducer and BMP receptor ligand. BMP2-derived peptide binds to BMP receptors on the cell surface to form a complex, activates the downstream Smad signaling pathway, and regulates the expression of osteogenic transcription factors. BMP2-derived peptide effectively promotes the adhesion, proliferation, osteogenic differentiation and mineralization of bone marrow mesenchymal stem cells, significantly up-regulates the mRNA levels of OCN, Runx2 and type I collagen, and increases alkaline phosphatase activity and calcium deposition. BMP2-derived peptide induces osteoblast differentiation and ectopic bone regeneration, and improves cranial bone defect repair. Meanwhile, BMP2-derived peptide enhances the cytocompatibility of mesoporous silica nanoparticles, synergistically increases osteogenic activity with Dexamethasone (HY-14648), serving as an important tool for bone defect repair research .
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Cat. No.: HY-108531
CAS No.: 187400-85-7
Purity:  99.86%
Target:  

RAR/RXR

Research Areas:  

Metabolic Disease

ER 50891 is a RARα antagonist. ER 50891 can significantly antagonize the inhibitory effect of all-trans retinoic acid (ATRA) on the total cell metabolic activity and proliferation of MC3T3-E1 preosteoblasts. ER 50891 rescues ATRA-inhibited osteocalcin (OCN) expression and extracellular matrix mineralization, and suppresses alkaline phosphatase (ALP) activity synergistically. ER 50891 can be used for the study of osteoporosis related to ATRA-induced inhibition of osteoblastogenesis .
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Cat. No.: HY-Y0332G
CAS No.: 7778-77-0
Synonyms: Potassium phosphate monobasic, for molecular biology
Potassium dihydrogen phosphate, for molecular biology (Potassium phosphate monobasic, for molecular biology) is a potassium salt. Potassium dihydrogen phosphate, for molecular biology activates NF-κB. Potassium dihydrogen phosphate, for molecular biology upregulates the expression of dental/osteogenic markers (OCN, DSP/DSPP, OSX, RUNX2, ALP) and enhances the mineralization capacity of human periodontal ligament stem cells. Potassium dihydrogen phosphate, for molecular biology promotes the proliferation of human periodontal ligament stem cells in logarithmic growth phase. Potassium dihydrogen phosphate, for molecular biology promotes the growth of somatic embryos of Dendrobium Sonia, increases leaf number, leaf length and fresh weight of tissue-cultured seedlings. Potassium dihydrogen phosphate, for molecular biology is applicable to periodontal disease-related research .
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Cat. No.: HY-Y0332L
CAS No.: 7778-77-0
Synonyms: Potassium phosphate monobasic, meets analytical specification of Ph. Eur., NF, E340
Potassium dihydrogen phosphate, meets analytical specification of Ph. Eur., NF, E340 (Potassium phosphate monobasic, meets analytical specification of Ph. Eur., NF, E340) is a potassium salt. Potassium dihydrogen phosphate, meets analytical specification of Ph. Eur., NF, E340 activates NF-κB. Potassium dihydrogen phosphate, meets analytical specification of Ph. Eur., NF, E340 upregulates the expression of dental/osteogenic markers (OCN, DSP/DSPP, OSX, RUNX2, ALP) and enhances the mineralization capacity of human periodontal ligament stem cells. Potassium dihydrogen phosphate, meets analytical specification of Ph. Eur., NF, E340 promotes the proliferation of human periodontal ligament stem cells in logarithmic growth phase. Potassium dihydrogen phosphate, meets analytical specification of Ph. Eur., NF, E340 promotes the growth of somatic embryos of Dendrobium Sonia, increases leaf number, leaf length and fresh weight of tissue-cultured seedlings. Potassium dihydrogen phosphate, meets analytical specification of Ph. Eur., NF, E340 is applicable to periodontal disease-related research .
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Cat. No.: HY-108531A
Purity:  99.86%
Target:  

RAR/RXR

Research Areas:  

Cancer

ER 50891 quarterhydrate is a RARα antagonist. ER 50891 can significantly antagonize the inhibitory effect of all-trans retinoic acid (ATRA) on the total cell metabolic activity and proliferation of MC3T3-E1 preosteoblasts. ER 50891 rescues ATRA-inhibited osteocalcin (OCN) expression and extracellular matrix mineralization, and suppresses alkaline phosphatase (ALP) activity synergistically. ER 50891 can be used for the study of osteoporosis related to ATRA-induced inhibition of osteoblastogenesis .
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Cat. No.: HY-Y0332J
CAS No.: 7778-77-0
Synonyms: Potassium phosphate monobasic (Pharmaceutical primary standard, USP)
Potassium dihydrogen phosphate, United States Pharmacopeia (USP) Reference Standard (Potassium phosphate monobasic (Pharmaceutical primary standard, USP)) is a potassium salt. Potassium dihydrogen phosphate, United States Pharmacopeia (USP) Reference Standard activates NF-κB. Potassium dihydrogen phosphate, United States Pharmacopeia (USP) Reference Standard upregulates the expression of dental/osteogenic markers (OCN, DSP/DSPP, OSX, RUNX2, ALP) and enhances the mineralization capacity of human periodontal ligament stem cells. Potassium dihydrogen phosphate, United States Pharmacopeia (USP) Reference Standard promotes the proliferation of human periodontal ligament stem cells in logarithmic growth phase. Potassium dihydrogen phosphate, United States Pharmacopeia (USP) Reference Standard promotes the growth of somatic embryos of Dendrobium Sonia, increases leaf number, leaf length and fresh weight of tissue-cultured seedlings. Potassium dihydrogen phosphate, United States Pharmacopeia (USP) Reference Standard is applicable to periodontal disease-related research .
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Cat. No.: HY-RS01488
Research Areas:  

Others

BGLAP Human Pre-designed siRNA Set A contains three designed siRNAs for BGLAP gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-N4119R
CAS No.: 13241-32-2
Neoeriocitrin (Standard) is the analytical standard of Neoeriocitrin (HY-N4119). This product is intended for research and analytical applications. Neoeriocitrin is a Naringin (HY-N0153) analogue found in Drynaria Rhizome. Neoeriocitrin induces cells proliferation, differentiation, up-regulates type I collagen, osteocalcin, and key osteogenic markers, and increases ALP activity. Neoeriocitrin increases expression of Runx2, COL I, OCN and Beclin1. Neoeriocitrin inhibits phosphorylation of P38 mitogen-activated protein kinase, reduces acetylcholinesterase (AChE) activity, and increases choline acetyltransferase (ChAT) activity. Neoeriocitrin reduces apoptosis and induces autophagy. Neoeriocitrin can be used for the researches of osteoporosis and Alzheimer's disease .
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Cat. No.: HY-145584A
CAS No.: 2055357-65-6
Synonyms: JPI-547/OCN-201 hydrochloride
Target:  

PARP Wnt β-catenin

Research Areas:  

Cancer

Nesuparib (JPI-547) hydrochloride is the orally active inhibitor for PARP 1/2 and Tankyrase 1/2 that inhibits tankyrases 1, tankyrases 2, and PARP 1 with IC50s of 5, 1 and 2 nM, respectively. Nesuparib hydrochloride exhibits antitumor activity and can be used in research of advanced solid tumor .
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Cat. No.: HY-P72104
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: BGLAP; BGP; Bone Gamma-Carboxyglutamate Protein; Bone Gla Protein; Gamma-Carboxyglutamic Acid-Containing Protein; Bone Gamma-Carboxyglutamate (Gla) Protein (Osteocalcin); Osteocalcin; Bone Gamma-Carboxyglutamate (Gla) Protein; OCN; OC
Species:  
Rat
Source:  
E. coli
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Cat. No.: HY-P72103
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: BGLAP; BGP; Bone Gamma-Carboxyglutamate Protein; Bone Gla Protein; Gamma-Carboxyglutamic Acid-Containing Protein; Bone Gamma-Carboxyglutamate (Gla) Protein (Osteocalcin); Osteocalcin; Bone Gamma-Carboxyglutamate (Gla) Protein; OCN; OC
Species:  
Mouse
Source:  
E. coli
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