Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
12 Results for "
OGG1
" in MedChemExpress (MCE) Product Catalog:
Products (12)
12 Results for "OGG1" in MCE Product Catalog:
4
4 Cited Publications
Target:
Research Areas:
SU0268 is a potent and specific inhibitor of 8-Oxoguanine DNA glycosylase 1 (OGG1). SU0268 regulates inflammatory responses during Pseudomonas aeruginosa infection [1] .
3
2
2 Cited Publications
Target:
Research Areas:
TH10785 is a DNA glycosylase 1 (OGG1) activator, TH10785 can interact with the phenylalanine-319 and glycine-42 amino acids of OGG1 and increase the enzyme activity, generates β, δ-lyase enzymatic function. TH10785 can control the catalytic activity mediated by a nitrogen base within its molecular structure. TH10785 can be used for the research of various diseases and aging connected with DNA oxidative lesions [1].
2
2 Cited Publications
Target:
Research Areas:
OGG1-IN-08 is a potent 8-oxoguanine DNA glycosylase-1 (OGG1) inhibitor with an IC50 value of 0.22 μM. OGG1-IN-08 decreases both the glycosylase and lyase activities of OGG1 [1].
1
1
Cat. No.: HY-RS09763
Target:
Research Areas:
OGG1 Human Pre-designed siRNA Set A contains three designed siRNAs for OGG1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-179014
Target:
Research Areas:
OGG1 activator-1 (Compound 30) is a selective 8-oxoguanine DNA glycosylase-1 (OGG1) activator with an AC50 value of 0.58 μM. OGG1 activator-1 does not activate nor inhibit the key downstream repair enzyme APE1, and shows > 150-fold selectivity for the activation effect on OGG1. OGG1 activator-1 exhibits extremely high metabolic stability and almost no cytotoxicity. OGG1 activator-1 can be used for the study of oxidative stress-related diseases (such as neurodegenerative diseases, fibrotic diseases, cancer, inflammation, etc.) [1].
Cat. No.: HY-RS16757
Target:
Research Areas:
Ogg1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Ogg1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS23196
Target:
Research Areas:
Ogg1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Ogg1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-180404
CAS No.: 2598151-90-5
Target:
Research Areas:
SU0383 is a dual MTH1 and OGG1 inhibitor with IC50 values of 0.034 μM and 0.49 μM, respectively. SU0383 induces cytotoxicity in cancer cells and increases sensitivity of tumor cells to oxidative stress, and showing low toxicity in normal cells. SU0383 can be used for cancer research [1] .
Cat. No.: HY-P72338A
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: 8-oxoguanine DNA glycosylase; 8-hydroxyguanine DNA glycosylase; MMH; MUTM; OGH1
- 1
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
