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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
8 Results for "
OSC
" in MedChemExpress (MCE) Product Catalog:
Products (8)
8 Results for "OSC" in MCE Product Catalog:
13
13 Cited Publications
Cat. No.: HY-18630A
CAS No.: 189197-69-1
Target:
Research Areas:
Ro 48-8071 is an inhibitor of OSC (Oxidosqualene cyclase) with IC50 of appr 6.5 nM.
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Research Areas:
BIBB 515 is a potent, selective and orally active 2,3-oxidosqualene cyclase (OSC) inhibitor with ED50 values of 0.2-0.5 mg/kg and 0.36-33.3 mg/kg in rats and mice (1-5 hours), respectively. BIBB 515 exerts lipid-lowering effect mainly by inhibiting the production of low-density lipoprotein (LDL) .
Cat. No.: HY-18630
CAS No.: 161582-11-2
Target:
Research Areas:
Ro 48-8071 is an inhibitor of OSC (Oxidosqualene cyclase) with IC50 of appr 6.5 nM.
Cat. No.: HY-162680
Target:
Research Areas:
OSC-GCDI(P) is a broad-spectrum orally active anti-influenza virus agent that exhibits significant inhibitory effects against both wild-type and Oseltamivir (HY-13317) resistant (H275Y) influenza virus strains in mouse infection models. OSC-GCDI(P) is capable of preventing not only wild-type influenza viruses but also OS-resistant variants with NA(H275Y) .
Cat. No.: HY-RS07866
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Research Areas:
LSS Human Pre-designed siRNA Set A contains three designed siRNAs for LSS gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P72309
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: LSS; 2,3-Epoxysqualene--Lanosterol Cyclase; Lanosterol Synthase; 2,3-Epoxysqualene-Lanosterol Cyclase; OSC; Oxidosqualene-Lanosterol Cyclase; Lanosterol Synthase (2,3-Oxidosqualene-Lanosterol Cyclase); CTRCT44; Oxidosqualene--Lanosterol Cyclase; HYPT14; H
Species:
Human
Source:
P. pastoris
Cat. No.: HY-RS17396
Target:
Research Areas:
Lss Mouse Pre-designed siRNA Set A contains three designed siRNAs for Lss gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-188066
CAS No.: 359715-57-4
Research Areas:
S23515 is a highly selective I1 imidazoline receptor (I1R) agonist with a Ki value of 6.4 nM. S23515 modulates central cardiovascular functions, induces hypotension and bradycardia, shows no affinity for α-adrenergic receptors, and cannot cross the blood-brain barrier. S23515 inhibits oxidosqualene-lanosterol cyclase (OSC) and cholesterol synthesis, induces the production of (24S,25)-Epoxycholesterol (HY-W040150), and upregulates the expression of ABCA1 and ABCG1 in human macrophages. S23515 is applicable to research related to dyslipidemia and hypertension .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
