68 Results for "

Octapeptide

" in MedChemExpress (MCE) Product Catalog:
Products (68)

68 Results for "Octapeptide" in MCE Product Catalog:

16
Octreotide
Octreotide
0 Images
16 Publications Verification
Referencia número: HY-P0036
No. CAS: 83150-76-9
Synonyms: SMS 201-995
Target:  

Somatostatin Receptor Apoptosis

Áreas de investigación:  

Cardiovascular Disease Inflammation/Immunology Endocrinology Cancer

Octreotide (SMS 201-995) is a somatostatin receptor agonist and synthetic octapeptide endogenous somatostatin analogue. Octreotide (SMS 201-995) can bind to the somatostatin receptor and mainly subtypes 2, 3, and 5, increases Gi activity, and reduces intracellular cAMP production. Octreotide (SMS 201-995) has antitumor activity, mediates apoptosis and may also be used in disease studies in acromegaly .
loading...
    loading...
View All Sizes
4
Sincalide
Sincalide
0 Images
4 Cited Publications
Referencia número: HY-P0093
No. CAS: 25126-32-3
Synonyms: Cholecystokinin Octapeptide; CCK-8; SQ19844
Target:  

Cholecystokinin Receptor Apoptosis PI3K Akt

Áreas de investigación:  

Infection Cancer

Sincalide (Cholecystokinin octapeptide, CCK-8) is a rapid-acting amino acid polypeptide hormone analogue of cholecystokinin (CCK) for intravenous use in postevacuation cholecystography. Sincalide is a major bioactive segment of CCK that retains most of the biological activities of CCK. Sincalide can promote gallbladder contraction by injection and helps diagnose gallbladder and pancreas disorders. Sincalide can increase bile secretion, cause the gallbladder to contract and relax the sphincter of Oddi, resulting in bile drainage into the duodenum. Sincalide is a major bioactive segment of CCK that retains most of the biological activities of CCK .
loading...
    loading...
View All Sizes
4
Sincalide ammonium
Sincalide ammonium
0 Images
4 Cited Publications
Referencia número: HY-P0093A
No. CAS: 70706-98-8
Synonyms: Cholecystokinin Octapeptide ammonium; CCK-8 ammonium; SQ19844 ammonium
Target:  

Cholecystokinin Receptor Apoptosis PI3K Akt

Áreas de investigación:  

Infection Cancer

Sincalide ammonium (Cholecystokinin octapeptide ammonium, CCK-8 ammonium) is a rapid-acting amino acid polypeptide hormone analogue of cholecystokinin (CCK) for intravenous use in postevacuation cholecystography. Sincalide ammonium is a major bioactive segment of CCK that retains most of the biological activities of CCK. CCK‐8 can promote gallbladder contraction by injection and helps diagnose gallbladder and pancreas disorders. Sincalide ammonium can increase bile secretion, cause the gallbladder to contract and relax the sphincter of Oddi, resulting in bile drainage into the duodenum. Sincalide ammonium is a major bioactive segment of CCK that retains most of the biological activities of CCK .
loading...
    loading...
View All Sizes
3
CYN 154806
CYN 154806
0 Images
3 Cited Publications
Referencia número: HY-P1202
No. CAS: 183658-72-2
Target:  

Somatostatin Receptor

Áreas de investigación:  

Endocrinology

CYN 154806, a cyclic octapeptide, is a potent and selective somatostatin sst2 receptor antagonist, with pIC50 values of 8.58, 5.41, 6.07, 5.76 and 6.48 for human recombinant sst2, sst1, sst3, sst4 and sst5 receptors respectively .
loading...
    loading...
View All Sizes
3
CYN 154806 TFA
CYN 154806 TFA
0 Images
3 Cited Publications
Referencia número: HY-P1202A
No. CAS: 2828432-46-6
Target:  

Somatostatin Receptor

Áreas de investigación:  

Endocrinology

CYN 154806 TFA, a cyclic octapeptide, is a potent and selective somatostatin sst2 receptor antagonist, with pIC50 values of 8.58, 5.41, 6.07, 5.76 and 6.48 for human recombinant sst2, sst1, sst3, sst4 and sst5 receptors respectively .
loading...
    loading...
View All Sizes
2
Cholecystokinin Octapeptide, desulfated
Cholecystokinin Octapeptide, desulfated
0 Images
2 Cited Publications
Referencia número: HY-P0196
No. CAS: 25679-24-7
Synonyms: CCK Octapeptide, desulfated
Target:  

Cholecystokinin Receptor

Áreas de investigación:  

Inflammation/Immunology

Cholecystokinin Octapeptide, desulfated (CCK Octapeptide, desulfated) is a synthetic desulfated Cholecystokinin octapeptide (HY-P0093).
loading...
    loading...
View All Sizes
2
Cholecystokinin Octapeptide, desulfated TFA
Cholecystokinin Octapeptide, desulfated TFA
0 Images
2 Cited Publications
Referencia número: HY-P0196A
No. CAS: 171486-94-5
Synonyms: CCK Octapeptide, desulfated TFA
Target:  

Cholecystokinin Receptor

Áreas de investigación:  

Inflammation/Immunology

Cholecystokinin Octapeptide, desulfated (CCK Octapeptide, desulfated) TFA is a synthetic desulfated Cholecystokinin octapeptide (HY-P0093).
loading...
    loading...
View All Sizes
1
m-PEG2000-NHS ester
m-PEG2000-NHS ester
0 Images
1 Cited Publications
Referencia número: HY-W591424
No. CAS: 92451-01-9
Synonyms: mPEG2000-SC; mPEG2000-Succinimidyl ester
m-PEG2000-NHS ester (mPEG2000-SC) is a reagent with both cell adhesion inhibition and peptide conjugation functions. The NHS ester group of m-PEG2000-NHS ester forms stable amide bonds with primary amine-containing molecules (e.g., the N-terminus of MMP-2-cleavable octapeptide) to generate mPEG-peptide intermediates for liposome surface modification. When m-PEG2000-NHS ester is immobilized on a cystamine-modified gold surface, it can construct an in vitro model for cell adhesion kinetic studies, and higher PEG density and thicker layers correlate with lower cell adhesion rates. m-PEG2000-NHS ester can synthesize MMP-2-responsive PEGylated lipid conjugates to achieve MMP-triggered dePEGylation in the tumor microenvironment. m-PEG2000-NHS ester can be used in studies related to colon cancer and other conditions .
loading...
    loading...
View All Sizes
1
Peptide T
Peptide T
0 Images
1 Cited Publications
Referencia número: HY-P0272
No. CAS: 106362-32-7
Target:  

HIV

Áreas de investigación:  

Infection

Peptide T is an octapeptide from the V2 region of HIV-1 gp120. Peptide T is a ligand for the CD4 receptor and prevents binding of HIV to the CD4 receptor.
loading...
    loading...
View All Sizes
1
C3a (70-77) TFA
C3a (70-77) TFA
0 Images
1 Cited Publications
Referencia número: HY-P1505A
Synonyms: Complement 3a (70-77) TFA
Target:  

Complement System

Áreas de investigación:  

Inflammation/Immunology

C3a (70-77) TFA (Complement 3a (70-77) TFA) is an octapeptide corresponding to the COOH terminus of C3a, exhibits the specificity and 1 to 2% biologic activities of C3a .
loading...
    loading...
View All Sizes
1
BIM 23042 TFA
BIM 23042 TFA
0 Images
1 Cited Publications
Referencia número: HY-103277A
Pureza:  96.20%
Target:  

Bombesin Receptor

Áreas de investigación:  

Neurological Disease Metabolic Disease

BIM 23042 TFA, a certain somatostatin (SS) octapeptide analogue, is a selective neuropeptide neuromedin B receptor (NMB-R, BB1) antagonist. BIM 23042 has 100-fold lower affinity for gastrin-releasing peptide (GRP) receptor (BB2). BIM 23042 inhibits Neuromedin?B?(HY-P0241), ICI 216140 and DPDM-bombesin ethylamide-induced Ca 2+ release .
loading...
    loading...
View All Sizes
Saralasin
Saralasin
0 Images
Referencia número: HY-P0205
No. CAS: 34273-10-4
Synonyms: [Sar1,Ala8] Angiotensin II
Target:  

Angiotensin Receptor

Áreas de investigación:  

Cardiovascular Disease Inflammation/Immunology

Saralasin ([Sar1,Ala8] Angiotensin II) is an octapeptide analog of angiotensin II. Saralasin is a competitive angiotensin II receptor antagonist with a Ki value of 0.32 nM for 74% of the binding sites, and has partial agonist activity as well. Saralasin can be used for the research of renovascular hypertension, renin-dependent (angiotensinogenic) hypertension .
loading...
    loading...
View All Sizes
Neuropeptide FF
Neuropeptide FF
0 Images
Referencia número: HY-P1248
No. CAS: 99566-27-5
Synonyms: NPFF
Target:  

Neuropeptide FF Receptor

Áreas de investigación:  

Cardiovascular Disease Neurological Disease

Neuropeptide FF (NPFF), an octapeptide belonging to the RF-amide family of peptides, is a NPFF1 and NPFF2 receptors agonist with Ki values of 2.82 nM and 0.21 nM, respectively. Neuropeptide FF induces abstinence syndrome, exerts antiopioid and analgesic effects, releases via calcium-dependent mechanisms from rat spinal cord, regulates memory, autonomic function, and neuroendocrine function, modulates pain and opioid antinociception, reduces food intake, stimulates water intake, alters cardiovascular parameters, and shows differential activity in hypothalamic paraventricular nucleus neurons. Neuropeptide FF is present in mammalian central nervous system and periphery, with NPFF-immunoreactivity increases in rat cerebrospinal fluid during opiate tolerance, and its NPFF gene and NPFF-R2 gene are up-regulated in rat spinal cord and dorsal root ganglia during peripheral inflammation. Neuropeptide FF can be used for the research of opioid tolerance, morphine-induced analgesia, abstinence syndrome, pain, hypertension, nociception, inflammatory pain, and neuropathic pain .
loading...
    loading...
View All Sizes
Adrenorphin
Adrenorphin
0 Images
Referencia número: HY-P1087
No. CAS: 88377-68-8
Synonyms: Metorphamide
Target:  

Opioid Receptor

Áreas de investigación:  

Cancer

Adrenorphin is a opioid octapeptide, acting as a potent agonist of μ-opioid receptor, with Ki of 12 nM.
loading...
    loading...
View All Sizes
Saralasin TFA
Saralasin TFA
0 Images
Referencia número: HY-P0205B
No. CAS: 2938955-39-4
Synonyms: [Sar1,Ala8] Angiotensin II TFA
Target:  

Angiotensin Receptor

Áreas de investigación:  

Cardiovascular Disease Inflammation/Immunology

Saralasin ([Sar1,Ala8] Angiotensin II) TFA is an octapeptide analog of angiotensin II. Saralasin TFA is a competitive angiotensin II receptor antagonist with a Ki value of 0.32 nM for 74% of the binding sites, and has partial agonist activity as well. Saralasin TFA can be used for the research of renovascular hypertension, renin-dependent (angiotensinogenic) hypertension .
loading...
    loading...
View All Sizes
BIM-23056
BIM-23056
0 Images
Referencia número: HY-P1203
No. CAS: 150155-61-6
Target:  

Somatostatin Receptor

Áreas de investigación:  

Neurological Disease

BIM 23056, a linear octapeptide, is a potent sst3 and sst5 somatostatin receptor antagonist with Ki values of 10.8, 5.7, respectively .
loading...
    loading...
View All Sizes
Oxyntomodulin (human, mouse, rat)
Oxyntomodulin (human, mouse, rat)
0 Images
Referencia número: HY-P4796
No. CAS: 159002-68-3
Synonyms: Proglucagon (33-69)
Target:  

Peptides

Áreas de investigación:  

Metabolic Disease

Oxyntomodulin (human, mouse, rat) (Proglucagon (33-69)) is a product of the glucagon precursor. Oxyntomodulin (human, mouse, rat) contains the entire glucagon sequence plus a C-terminal octapeptide, comprising in total 37 amino acids.
loading...
    loading...
View All Sizes
Octapeptide-2
Octapeptide-2
0 Images
Referencia número: HY-P5253
No. CAS: 1374396-34-5
Target:  

Apoptosis

Áreas de investigación:  

Metabolic Disease

Octapeptide-2 is a biomimetic peptide that mimics the thymosin-β4 growth factor. Octapeptide-2 can promote hair growth, reduce cell apoptosis, and increase the proliferation of keratinocytes. Octapeptide-2 can be used in the research of hair loss and alopecia areata .
loading...
    loading...
View All Sizes
Dexloxiglumide
Dexloxiglumide
0 Images
Referencia número: HY-128878
No. CAS: 119817-90-2
Pureza:  98.25%
Target:  

Cholecystokinin Receptor P-glycoprotein

Áreas de investigación:  

Metabolic Disease Endocrinology

Dexloxiglumide is an orally active and selective cholecystokinin type A (CCKA) receptor antagonist. Dexloxiglumide is the active enantiomer of Loxiglumide, inhibits smooth muscle cell contractions induced by cholecystokinin-octapeptide (CCK-8). Dexloxiglumide exhibits moderate Caco-2 permeability that is polarized, concentration dependent, and pH dependent. Dexloxiglumide increases MRP1-substrate fluorescein uptake. Dexloxiglumide can be studied in research for gastrointestinal diseases and tumors .
loading...
    loading...
View All Sizes
Acetyl octapeptide-1
Acetyl octapeptide-1
0 Images
Referencia número: HY-P0065
No. CAS: 868844-74-0
Target:  

Peptides

Áreas de investigación:  

Others

Acetyl octapeptide-1 is a bioactive peptide with anti-wrinkle effect and has been reported used as a cosmetic ingredient .
loading...
    loading...
View All Sizes
Assay Types