13 Results for "

PACE4

" in MedChemExpress (MCE) Product Catalog:
Products (13)

13 Results for "PACE4" in MCE Product Catalog:

7
7 Cited Publications
Cat. No.: HY-P1028
CAS No.: 673202-67-0
Synonyms: Furin Inhibitor II
Target:  

Bacterial

Research Areas:  

Infection

Hexa-D-arginine (Furin Inhibitor II) is a stable furin inhibitor with Ki values 106 nM, 580 nM and 13.2 μM for furin, PACE4 and prohormone convertase-1 (PC1), respectively. Hexa-D-arginine blocks Pseudomonas exotoxin A and anthrax toxins toxicity in vitro and in vivo .
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7
7 Cited Publications
Cat. No.: HY-P1028A
CAS No.: 958204-56-3
Synonyms: Furin Inhibitor II TFA
Target:  

Bacterial

Research Areas:  

Infection

Hexa-D-arginine TFA (Furin Inhibitor II TFA) is a stable furin inhibitor with Ki values 106 nM, 580 nM and 13.2 μM for furin, PACE4 and prohormone convertase-1 (PC1), respectively. Hexa-D-arginine TFA blocks Pseudomonas exotoxin A and anthrax toxins toxicity in vitro and in vivo .
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Cat. No.: HY-P10816
CAS No.: 1426656-94-1
Synonyms: Ac-(DLeu)LLLRVK-Amba
Target:  

Bacterial

Research Areas:  

Infection Cancer

PACE4 Inhibitory peptide C23 (Compound C23; Ac-(DLeu)LLLRVK-Amba)), a potent peptidomimetic inhibitor, is a PACE4 inhibitor. PACE4 Inhibitory peptide C23e shows antiproliferative effects against PCa cell lines (Ki = 5 nM; IC50 = 25 and 40 μM for DU145 and LNCaP, respectively). PACE4 Inhibitory peptide C23 also blocks tumor growth in vivo in LNCaP xenograft-bearing mice .
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Cat. No.: HY-P10422A
Synonyms: ML-peptide, Multi-Leucine (ML)-peptide triacetate
Target:  

Autophagy

Research Areas:  

Cancer

Multi-Leu peptide (ML-peptide) triacetate is a potent inhibitor of PACE4 (Ki=22 nM). Multi-Leu peptide triacetate can competitively bind to the active site of PACE4 by simulating the substrate sequence of PACE4, thereby inhibiting its catalytic activity. Multi-Leu peptide triacetate can be used to study the specific mechanism of PACE4 in the development of prostate cancer .
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Cat. No.: HY-110147B
Purity:  ≥99.0%
Target:  

Furin

Research Areas:  

Infection

SSM-3 tetraTFA hydrate is a potent furin inhibitor with an EC50 of 54 nM. SSM-3 tetraTFA hydrate uses its positively charged guanidyl group to form strong electrostatic interactions with the negatively charged residues in the catalytic center of furin, thereby competitively occupying and blocking the active site. SSM-3 tetraTFA hydrate can be used in the research of anthrax and avian influenza .
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Cat. No.: HY-P10422
CAS No.: 1413058-07-7
Synonyms: ML-peptide, Multi-Leucine (ML)-peptide
Target:  

Autophagy

Research Areas:  

Cancer

Multi-Leu peptide (ML-peptide) is a potent inhibitor of PACE4 (Ki=22 nM). Multi-Leu peptide can competitively bind to the active site of PACE4 by simulating the substrate sequence of PACE4, thereby inhibiting its catalytic activity. Multi-Leu peptide can be used to study the specific mechanism of PACE4 in the development of prostate cancer .
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Cat. No.: HY-P700617
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: PCSK6; SPC4; Prev. PACE4; Paired Basic Amino Acid Cleaving System 4; Subtilisin-Like Proprotein Convertase 4; Alternative Protein PCSK6; Subtilisin/Kexin-Like Protease PACE4; Subtilisin-Like Protease; Proprotein Convertase Subtilisin/Kexin Type 6; Paired
Species:  
Human
Source:  
E. coli
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Cat. No.: HY-P700621
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: PCSK6; SPC4; Prev. PACE4; Paired Basic Amino Acid Cleaving System 4; Subtilisin-Like Proprotein Convertase 4; Alternative Protein PCSK6; Subtilisin/Kexin-Like Protease PACE4; Subtilisin-Like Protease; Proprotein Convertase Subtilisin/Kexin Type 6; Paired
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-RS10175
Research Areas:  

Others

PCSK6 Human Pre-designed siRNA Set A contains three designed siRNAs for PCSK6 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-110147A
CAS No.: 2320930-10-5
Target:  

Furin

Research Areas:  

Infection

SSM-3 tetraTFA is a potent furin inhibitor with an EC50 of 54 nM. SSM-3 tetraTFA uses its positively charged guanidyl group to form strong electrostatic interactions with the negatively charged residues in the catalytic center of furin, thereby competitively occupying and blocking the active site. SSM-3 tetraTFA can be used in the research of anthrax and avian influenza .
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Cat. No.: HY-RS29225
Research Areas:  

Others

Pcsk6 Rat Pre-designed siRNA Set A contains three designed siRNAs for Pcsk6 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
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Cat. No.: HY-RS22711
Research Areas:  

Others

Pcsk6 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Pcsk6 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-110147
CAS No.: 922732-52-3
Target:  

Furin

Research Areas:  

Infection

SSM-3 is a potent furin inhibitor with an EC50 of 54 nM. SSM-3 uses its positively charged guanidyl group to form strong electrostatic interactions with the negatively charged residues in the catalytic center of furin, thereby competitively occupying and blocking the active site. SSM-3 can be used in the research of anthrax and avian influenza .
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