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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
36 Results for "PDF
" in MedChemExpress (MCE) Product Catalog:
Products (36)
36 Results for "PDF" in MCE Product Catalog:
7
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3
Cat. No.: HY-P10400
CAS No.: 902781-11-7
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Synonyms: GSK 1322322
Lanopepden (GSK 1322322) is a peptide deformylase (PDF) inhibitor. Lanopepden exerts antibacterial activity by inhibiting the activity of PDF and preventing the correct synthesis of bacterial proteins. Lanopepden can be used for the research of acute bacterial skin and skin structure infections .
Cat. No.: HY-102008
CAS No.: 478913-91-6
Synonyms: NVP-PDF 713; VIC-104959
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LBM-415 (NVP-PDF 713) is a peptide deformylase (PDF) inhibitor that exhibits inhibitory activity against various antimicrobial-resistant gram-positive cocci, with a MIC90 range of 0.12-8 µg/ml. Additionally, inhibiting efflux pump activity can enhance bacterial sensitivity to LBM415, thereby improving its antibacterial efficacy .
Cat. No.: HY-136885
CAS No.: 143457-40-3
(S,S)-TAPI-0 is a matrix metalloproteinase (MMP) inhibitor that inhibits the growth of Chlamydia trachomatis by inhibiting PDF enzyme activity. (S,S)-TAPI-0 can be used to study Chlamydia infection .
Cat. No.: HY-114900
CAS No.: 235784-88-0
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BB-3497 is a potent, orally active and selective peptide deformylase (PDF) inhibitor. BB-3497 is highly selective for PDF (IC50 = 7 nM for E. coli PDF.Ni) over the other mammalian metalloenzymes (MMP-1/2/3/7 and enkephalinase). BB-3497 exhibits potent activity against gram-positive bacteria and some gram-negative pathogens. BB-3497 protects mice from infection in systemic models of Staphylococeus aureus. BB-3497 can be used for anti-bacterial infection research .
Cat. No.: HY-P10400A
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Cat. No.: HY-102009
CAS No.: 325795-25-3
BB-83698 is a peptide deformylase (PDF) inhibitor. BB-83698 exhibits potent in vitro activity against Streptococcus pneumoniae, with a minimum inhibitory concentration (MIC) range of 0.06-0.25μg/mL. BB-83698 elevates the survival rate of mice regardless of whether the infecting strain carries resistance mechanisms. BB-83698 can be used for the study of diseases related to drug-resistant Streptococcus pneumoniae infections .
Cat. No.: HY-177301
CAS No.: 949197-97-1
PDF-IN-2 is a peptidyl deformylase (PDF) inhibitor. PDF-IN-2 has average IC50 values of 0.25, 0.50 and 0.34 nM, and average MIC values of 0.16, 0.33 and 0.25 μg/mL for Streptococcus pneumoniae PDF WT, G70V and G70D, respectively. PDF-IN-2 can be used in the research of infectious diseases .
Cat. No.: HY-RS10249
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PDF Human Pre-designed siRNA Set A contains three designed siRNAs for PDF gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS23699
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Pdf Rat Pre-designed siRNA Set A contains three designed siRNAs for Pdf gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-113952R
CAS No.: 13434-13-4
Synonyms: (-)-Actinonin (Standard)
Category:
Cat. No.: HY-116598
CAS No.: 1441390-17-5
Synonyms: GSK 1322322 mesylate
Lanopepden mesylate (GSK 1322322 mesylate) is a peptide deformase (PDF) inhibitor. Lanopepden mesylate has antibacterial activity by inhibiting the activity of PDF, preventing the correct synthesis of bacterial proteins. Lanopepden mesylate mainly targets Gram-positive bacteria. Lanopepden mesylate can be used in the study of acute bacterial skin and skin structural infections .
Cat. No.: HY-119728
CAS No.: 197316-54-4
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Cat. No.: HY-168853
CAS No.: 3036109-97-1
Antibacterial agent 261 (compound 43) is a potent inhibitor of peptidomimetic peptide deformylase (PDF), with IC50 of 2.5 and 10.6 nM for S. aureus and E. coli, respectively .
Cat. No.: HY-RS05352
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GDF15 Human Pre-designed siRNA Set A contains three designed siRNAs for GDF15 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS17245
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Pdf Mouse Pre-designed siRNA Set A contains three designed siRNAs for Pdf gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P71767
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: def; def1; PDF1Peptide deformylase; PDF; Polypeptide deformylase
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
