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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
15 Results for "
PI4KB
" in MedChemExpress (MCE) Product Catalog:
Products (15)
15 Results for "PI4KB" in MCE Product Catalog:
4
4 Cited Publications
T-00127_HEV1 is a phosphatidylinositol 4-kinase III beta (PI4KB) inhibitor with an IC50 of 60 nM.
GSK-F1 (Compound F1) is an orally active PI4KA inhibitor with pIC50 values of 8.0, 5.9, 5.8, 5.9, 5.9 and 6.4 against PI4KA, PI4KB, PI3KA, PI3KB, PI3KG and PI3KD, respectively. GSK-F1 can be used for HCV infection research .
Cat. No.: HY-RS10469
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PI4KB Human Pre-designed siRNA Set A contains three designed siRNAs for PI4KB gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS10470
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Pi4kb Mouse Pre-designed siRNA Set A contains three designed siRNAs for Pi4kb gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS10471
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Pi4kb Rat Pre-designed siRNA Set A contains three designed siRNAs for Pi4kb gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-177725
CAS No.: 2413733-33-0
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MG degrader 2 (Compound CM-2) is a CRBN-dependent molecular glue degrader. MG degrader 2 induces ZFP91, FIZ1 and PI4KB degradation. MG degrader 2 has anti-proliferative activity against MM.1S cells (IC50 = 162 nM). MG degrader 2 can be used for the research of cancer, such as multiple myeloma .
Cat. No.: HY-22055B
CAS No.: 254882-14-9
Synonyms: (2S,4S)-1-tert-butyl 2-methyl-4-hydroxyPIperidine-1,2-dicarboxylate
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AN-12-H5 intermediate-1 ((2S,4S)-1-tert-butyl 2-methyl-4-hydroxypiperidine-1,2-dicarboxylate) is an intermediate of the viral inhibitor AN-12-H5 (HY-120900) and can be used to synthesize Antibody-Drug Conjugates (ADCs).
Cat. No.: HY-175557
CAS No.: 2411491-16-0
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PI4K-IN-2 (Compound 30) is a highly selective type III phosphatidylinositol 4-kinase β (PI4KB) inhibitor (IC50=0.015 μM). PI4K-IN-2 is promising for research of human rhinovirus (HRV) .
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AN-12-H5, an antienterovirus compound, targets the replication processes of PV and enterovirus 71 (EV71) .
Cat. No.: HY-P701742
Purity: ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: PI4KB; Phosphatidylinositol 4-kinase beta; PI4K-beta; PI4KBeta; PtdIns 4-kinase beta; NPIK; PI4K92; PI4KIII
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Cat. No.: HY-182721
CAS No.: 2380013-55-6
Pipinib is an ATP-competitive and selective phosphatidylinositol 4-kinase IIIb (PI4KB) inhibitor with an IC50 of 2.2 μM. Pipinib reduces intracellular PI4P levels. Pipinib inhibits GLI-mediated transcription, the expression of Hedgehog target genes, and blocks the trafficking of Smoothened to cilia. Pipinib can be used in the research of basal cell carcinoma and medulloblastoma .
Cat. No.: HY-108313R
CAS No.: 900874-91-1
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T-00127_HEV1 (Standard) is the analytical standard of T-00127_HEV1 (HY-108313). This product is intended for research and analytical applications. T-00127_HEV1 is a phosphatidylinositol 4-Kinase III beta (PI4KB) inhibitor with an IC50 of 60 nM.
Cat. No.: HY-W047496
CAS No.: 756486-14-3
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AN-12-H5 intermediate-2 is an intermediate of the viral inhibitor AN-12-H5 (HY-120900) and can be used to synthesize Antibody-Drug Conjugates (ADCs).
Cat. No.: HY-W451820
CAS No.: 851314-03-9
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AN-12-H5 intermediate-3 is an intermediate of the viral inhibitor AN-12-H5 (HY-120900) and can be used to synthesize Antibody-Drug Conjugates (ADCs).
Cat. No.: HY-100603B
CAS No.: 1384097-28-2
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(R)-GSK-F1 is the R-type isomer of GSK-F1 (HY-100603). GSK-F1 (Compound F1) is an orally active PI4KA inhibitor with pIC50 values of 8.0, 5.9, 5.8, 5.9, 5.9 and 6.4 against PI4KA, PI4KB, PI3KA, PI3KB, PI3KG and PI3KD, respectively. GSK-F1 can be used for HCV infection research .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
