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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
61 Results for "
PPO
" in MedChemExpress (MCE) Product Catalog:
Products (61)
61 Results for "PPO" in MCE Product Catalog:
Cat. No.: HY-139838
CAS No.: 353292-31-6
Epyrifenacil is a protoporphyrinogen oxidase (PPO) inhibiting herbicide, potently targeting the PPO2 isoform from weeds such as Amaranthus palmeri with an IC50 of 0.637 nM. Epyrifenacil also inhibits liver mitochondrial PPO across species, with IC50 values of 2.2 nM (mouse), 2.6 nM (rat), 12.1 nM (rabbit), 7.6 nM (dog), and 10.2 nM (human). Epyrifenacil induces liver tumor development in mice. Epyrifenacil can be used for weed control, and also used as a tool compound in toxicological research to study the mechanism of PPO inhibition, chemical-induced hepatotoxicity, and the mode of action of non-genotoxic carcinogens in rodents [3].
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Trifludimoxazin is a click chemistry reagent, a protoporphyrinogen oxidase (PPO) inhibitor and herbicide. Trifludimoxazin inhibits PPO, accumulates reactive oxygen species, damages cell membranes, and thereby causes weed death. Trifludimoxazin exhibits high-efficiency activity in controlling broadleaf weeds and grassy weeds .
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Tiafenacil is a new protoporphyrinogen IX oxidase (PPO)-inhibiting herbicide, with IC50 values of 22 to 28 nM for various plant species, including amaranth (Amaranthus tuberculatus), soybean (Glycine max), arabidopsis (Arabidopsis thaliana), and rapeseed (Brassica napus) .
Cat. No.: HY-W014018
CAS No.: 92-71-7
Synonyms: PPO; DPO; POP
Cat. No.: HY-W013673
CAS No.: 1482-97-9
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Pyraflufen-ethyl is a phenylpyrazole herbicide for control of annual and perennial broadleaf weeds. Pyraflufen-ethyl inhibits protoporphyrinogen oxidase (PPO). Pyraflufen-ethyl controls rosette Parthenium hysterophorus .
Cat. No.: HY-B2024
CAS No.: 99607-70-2
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Cloquintocet-mexyl is a herbicide safener. Cloquintocet-mexyl promotes the expression of genes related to chlorophyll synthesis (such as GTR and PPO) and chlorophyll-binding protein genes (CBP), increases the chlorophyll content, thereby promoting photosynthesis and reducing oxidative stress. Cloquintocet-mexyl improves wheat tolerance to Fomesafen (HY-B2010) .
Cat. No.: HY-B2010
CAS No.: 72178-02-0
Target:
Environmental Pollutants Reactive Oxygen Species (ROS) Herbicide Protoporphyrinogen IX oxidase Apoptosis
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Fomesafen is an orally active herbicide. Fomesafen inhibits protoporphyrinogen oxidase (PPO). Fomesafen induces Apoptosis and increases ROS. Fomesafen exhibits developmental toxicity, immunotoxicity, and neurotoxicity. It induces precancerous lesions in the liver and hepaturoporphyria in mice. Fomesafen is used to control broadleaf weeds in soybean fields, rubber plantations, and orchards .
Synonyms: V-53482
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Flumioxazin (V-53482) is a protoporphyrinogen IX oxidase (PPO) inhibitor with a rat target IC50 of 4.58 nM. Flumioxazin is found in its biological sources and is used for pre-emergence control of dicotyledonous weeds in soybean and peanut. Flumioxazin inhibits protoporphyrinogen oxidase, blocking chlorophyll and heme biosynthesis, leading to protoporphyrin IX accumulation, oxidative stress, membrane damage, and cell death. Flumioxazin is used in research on weed control .
Synonyms: Cy 3-soph
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Cat. No.: HY-17531
CAS No.: 158353-15-2
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Pyraclonil is a proporphyrinogen oxidase (PPO) inhibitor. Pyraclonil is a herbicide agent and is highly effective in controlling the susceptible (S) and multiple-herbicide-resistant (MHR) E. indica populations . Pyraclonil is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
Cat. No.: HY-178977
PPO-IN-23 is a potent protoporphyrinogen IX oxidase (PPO) inhibitor with a Ki of 12.4 nM. PPO-IN-23 forms two hydrogen bonds with the Arg98 residue of Nicotiana tabacum PPO (NtPPO). PPO-IN-23 exhibits potent herbicidal activity and good crop safety. PPO-IN-23 can be used for weeds management .
Cat. No.: HY-178026
CAS No.: 3087063-34-8
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HPPD/PPO-IN-1 (Compound B14) is dual-functional inhibitor of HPPD and PPO with IC50s of 0.12 μM and 0.51 μM for Arabidopsis thaliana HPPD and Nicotiana tabacum PPO, respectively. HPPD/PPO-IN-1 has broad-spectrum herbicidal activity against weeds with a crop safety to peanuts and cotton. HPPD/PPO-IN-1 can be used for the development of environmentally friendly herbicides .
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Cat. No.: HY-118923
CAS No.: 372137-35-4
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Saflufenacil is a herbicide of the pyrimidinedione chemical class preplant burndown and selective preemergence dicot weed control in multiple crops, including corn. Saflufenacil is a potent inhibitor of protoporphyrinogen IX oxidase (PPO) .
Cat. No.: HY-161951
CAS No.: 3029518-71-3
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PPO-IN-15 (compound (R)-I-5) is a protoporphyrinogen IX oxidase (PPO) inhibitor that is effective against resistant weeds and safer in wheat and rice .
Cat. No.: HY-157470
CAS No.: 125727-57-3
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PPO-IN-6 is a protoporphyrinogen oxidase (PPO) inhibitor that blocks the production of heme and chlorophyll. Pop-in-6 can be used IN the detection and research of cancer and other diseases .
Cat. No.: HY-161503
CAS No.: 3034607-58-1
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PPO-IN-10 (Compound 4) is a 2-phenylpyridine derivative of pyrrolidone. PPO-IN-10 inhibits protoporphyrinogen IX oxidase (PPO). PPO-IN-10 leads to the formation of photosensitive protoporphyrin IX and the death of weed leaves. PPO-IN-10 can be used in the research of developing new PPO herbicides .
Cat. No.: HY-149312
CAS No.: 1879036-82-4
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PPO-IN-3 (Compound 8ad) is a PPO inhibitor with an KI value of 0.67 nM. PPO-IN-3 has post-emergence herbicidal activity. PPO-IN-3 can be used for weed control .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
