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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
57 Results for "
RAGE
" in MedChemExpress (MCE) Product Catalog:
Products (57)
57 Results for "RAGE" in MCE Product Catalog:
71
71 Publications Verification
Cat. No.: HY-19370
CAS No.: 945714-67-0
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FPS-ZM1 is a high-affinity and BBB-permeable RAGE inhibitor with a Ki of 25 nM.
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Azeliragon (TTP488) is an orally bioavailable inhibitor of the receptor for advanced glycation end products (RAGE) in development as a potential treatment to slow disease progression with mild Alzheimer’s disease (AD) . Azeliragon also can cross the blood-brain barrier (BBB) .
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6 Cited Publications
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ABR-238901 is an orally active and potent S100A8/A9 blocker and inhibits S100A8/A9 interaction with its receptors RAGE (receptor for advanced glycation endproducts) and TLR4 (toll-like receptor 4). ABR-238901 has the potential for myocardial infarction (MI) research .
5
5 Cited Publications
Cat. No.: HY-W018772
CAS No.: 50-69-1
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5
5 Cited Publications
Cat. No.: HY-P2268
CAS No.: 1092460-91-7
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5
5 Cited Publications
Cat. No.: HY-P2268A
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1
1 Cited Publications
Synonyms: Glucogallin; 1-O-Galloyl-β-D-glucose
1
1 Cited Publications
Cat. No.: HY-W286743
CAS No.: 5746-04-3
Synonyms: CML; N6-(Carboxymethyl)-L-lysine; Nε-(1-Carboxymethyl)-L-lysine
1
Category:
Rheum palmatum L. Stilbenes Polygonaceae Phenols Polyphenols Plants Disease Research Fields Inflammation/Immunology
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1
1 Cited Publications
Cat. No.: HY-W017370
CAS No.: 99-48-9
1
1 Cited Publications
Cat. No.: HY-P7467
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: AGER; Receptor For Advanced Glycosylation End-Products Deletion Exon3-10 Variant; Advanced Glycosylation End-Product Specific Receptor; Receptor For Advanced Glycosylation End-Products Deletion Exon2-6 Variant; RAGE; Advanced Glycosylation End Product-Spe
1
1 Cited Publications
Cat. No.: HY-P71270
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: S100A12; ENRAGE; S100 Calcium Binding Protein A12; MRP6; CAAF1; Protein S100-A12; CGRP; Calgranulin C; CAGC; EN-RAGE; P6; MRP-6; Extracellular Newly Identified RAGE-Binding Protein; S100 Calcium-Binding Protein A12 (Calgranulin C); Migration Inhibitory Fa
Cat. No.: HY-NP165
Synonyms: AGEs
Cat. No.: HY-N3097
CAS No.: 18836-52-7
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RAGE 229 is an orally active ctRAGE-DIAPH1 inhibitor. RAGE 229 can inhibit the intracellular RAGE signaling by inhibiting the interaction between the cytoplasmic tail of RAGE(ctRAGE) and Diaphanous-1(DIAPH1) .
Cat. No.: HY-N0442
CAS No.: 84272-85-5
Synonyms: 4'-O-β-D-Glucosyl-5-O-methylvisamminol
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MI-389 is a potent menin-MLL interaction inhibitor (IC50=25 nM). MI-389 upregulates myeloid differentiation-related genes that are lowly expressed in primitive hematopoietic progenitor cells, thereby inducing myeloid differentiation phenotypic changes in MLL-rearranged leukemia cells. MI-389 competitively blocks the MG-H1-RAGE interaction to interfere with the AGEs-RAGE pathway, thus alleviating AGEs-induced HUVEC injury . MI-389 can be used in studies related to MLL-rearranged acute leukemia .
Cat. No.: HY-P990328
Synonyms: XT-M4
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S100P-IN-1 is a S100P inhibitor, and S100P is a calcium-binding protein. S100P-IN-1 potently inhibits the interaction between purified human S100P and RAGE-Fc protein, with an IC50 value of 22.7 nM. S100P-IN-1 exerts anti-metastatic effects on pancreatic cancer cells. S100P-IN-1 can be used for the research of pancreatic cancer .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
