13 Results for "

RBL2

" in MedChemExpress (MCE) Product Catalog:
Products (13)

13 Results for "RBL2" in MCE Product Catalog:

製品番号: HY-N2252
CAS 番号: 51020-86-1
別名: (+)-Licarin A
Licarin A ((+)-Licarin A), a neolignan, significantly and dose-dependently reduces TNF-α production (IC50=12.6 μM) in dinitrophenyl-human serum albumin (DNP-HSA)-stimulated RBL-2H3 cells. Anti-allergic effects. Licarin A reduces TNF-α and PGD2 production, and COX-2 expression .
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製品番号: HY-RS11730
研究分野:  

Others

RBL2 Human Pre-designed siRNA Set A contains three designed siRNAs for RBL2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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製品番号: HY-RS27934
研究分野:  

Others

Rbl2 Rat Pre-designed siRNA Set A contains three designed siRNAs for Rbl2 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
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製品番号: HY-RS21415
研究分野:  

Others

Rbl2 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Rbl2 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

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製品番号: HY-P1640
CAS 番号: 130154-64-2
Target:  

Complement System

研究分野:  

Inflammation/Immunology

(Trp63,Trp64)​-​C3a(63-77) is a C3a synthetic analogue peptide, which exhibits Ca 2+ stimulating efficacy in human neutrophils and hC3aR or mC3aR expressing RBL-2H3 cells with EC50 of 9.5, 2.0 and 0.8 nM, respectively .
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製品番号: HY-N15708
CAS 番号: 755036-45-4
別名: (R)-(-)-Dichotomine C
Dichotomine C ((R)-(-)-Dichotomine C) is a β-carboline-type alkaloid with antiallergic effects. Dichotomine C inhibits the release of β-hexosaminidase in RBL-2H3 cells with an IC50 of 62 μM. Dichotomine C inhibits the releases of antigen-IgE-mediated TNF-α and IL-4 in RBL-2H3 cells with IC50s of 19 μM and 15 μM, respectively. Dichotomine C can be used for the study of type I allergic reactions .
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製品番号: HY-N12116
CAS 番号: 1967042-42-7
Maceneolignan A is a natural product that can be isolated from mace, the aril of Myristica fragrans (Myristicaceae). Maceneolignan A inhibits the release of β-hexosaminidase in RBL-2H3 cells, with an IC50 of 48.4 μM. Maceneolignan A inhibits the release of TNF-α in antigen stimulated RBL-2H3 cells, with an IC50 of 63.7 μM .
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製品番号: HY-139247
CAS 番号: 2454246-25-2
Target:  

Drug Derivative

研究分野:  

Inflammation/Immunology

pNPS-DHA (Compound 19) is an orally active DHA-ethanolamide (DHEA) derivative that has antiallergic activity. pNPS-DHA inhibits IgE-dependent passive cutaneous anaphylaxis (PCA) reaction in mice. pNPS-DHA has anti-degranulating activity in RBL-2H3 mast cells with an IC50 of 15 μM .
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製品番号: HY-P11128
CAS 番号: 1427516-68-4
Target:  

阻害性抗体

研究分野:  

Others

Mastoparan-V1 is a peptide belonging to the Mastoparan family. Mastoparan-V1 exhibits modest mast cell degranulation activity, with EC50 of 130.24 μM in RBL-2H3 cells. Mastoparan-V1 can be used for the study of allergic reactions induced by wasp stings .
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製品番号: HY-P11163
CAS 番号: 255720-68-4
Target:  

Bacterial Glycosidase

研究分野:  

Infection

Eumenitin is an antibacterial peptide with strong membrane activity, broad-spectrum antibacterial activity, and almost no hemolytic toxicity. Eumenitin has inhibitory effects on various Gram positive and Gram negative bacteria. Eumenitin can induce the release of β-hexosaminidase from rat peritoneal mast cells and RBL-2H3 cells. Eumenitin can be used in the research of infectious conditions .
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製品番号: HY-N1186
CAS 番号: 109194-60-7
Tachioside is a phenolic glycoside natural product. Tachioside inhibits antigen-induced mast cell degranulation and TNF-α expression in RBL-2H3 cells; it exhibits melanin inhibitory effects in B16 melanoma cells. Tachioside possesses anti-obesity, antioxidant, and α-glucosidase inhibitory activities. Tachioside has been predicted as a potential anti-breast cancer candidate compound and shows high correlation coefficients with antioxidant indicators such as ABTS and FRAP. Tachioside can be used in research on allergies and pigmentation-related diseases [2] .
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製品番号: HY-116295
CAS 番号: 7077-89-6
MRS2690 is a selective P2Y14 receptor agonist. MRS2690 inhibits adenylyl cyclase activity, thereby reducing intracellular cAMP levels and mediating concentration-dependent vasoconstriction of porcine coronary arteries. MRS2690 induces intracellular calcium mobilization, activates P38 and stimulates [ 35S]GTPγS binding to RBL-2H3 cell membranes. MRS2690 enhances antigen (NP-BSA)-, C3a-induced β-hexosaminidase (β-Hex) release. MRS2690can be used for ischemic heart disease [2] .
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製品番号: HY-116295A
MRS2690 disodium is a selective P2Y14 receptor agonist. MRS2690 disodium inhibits adenylyl cyclase activity, thereby reducing intracellular cAMP levels and mediating concentration-dependent vasoconstriction of porcine coronary arteries. MRS2690 disodium induces intracellular calcium mobilization, activates P38 and stimulates [ 35S]GTPγS binding to RBL-2H3 cell membranes. MRS2690 enhances antigen (NP-BSA)-, C3a-induced β-hexosaminidase (β-Hex) release. MRS2690 disodium can be used for ischemic heart disease [2] .
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