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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
19 Results for "
SCG2
" in MedChemExpress (MCE) Product Catalog:
Products (19)
19 Results for "SCG2" in MCE Product Catalog:
Cat. No.: HY-RS12501
Target:
Research Areas:
SCG2 Human Pre-designed siRNA Set A contains three designed siRNAs for SCG2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS19380
Target:
Research Areas:
Scg2 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Scg2 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS25872
Target:
Research Areas:
Scg2 Rat Pre-designed siRNA Set A contains three designed siRNAs for Scg2 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-184689
CAS No.: 1311892-52-0
ORS-14 is a LILRB4/ILT3 ligand with a Kd of 85.2 nM for human receptors. ORS-14 blocks SCG2-mediated LILRB4 signaling pathway, reverses SCG2-mediated immunosuppression, restores cytokine production, reduces tumor cell viability, recovers cytotoxic T cell function, and increases the frequency of granzyme B + CD8 + T cells. ORS-14 can be used in research related to colorectal cancer and acute myeloid leukemia .
Cat. No.: HY-P703163
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: MEN1; Multiple Endocrine Neoplasia I; Menin 1; Truncated Menin; Menin; MEAI; SCG2
Species:
Human
Source:
E. coli
Cat. No.: HY-P703164
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: MEN1; Multiple Endocrine Neoplasia I; Menin 1; Truncated Menin; Menin; MEAI; SCG2
Species:
Human
Source:
E. coli
Cat. No.: HY-P703165
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: MEN1; Multiple Endocrine Neoplasia I; Menin 1; Truncated Menin; Menin; MEAI; SCG2
Species:
Human
Source:
E. coli
Cat. No.: HY-P703166
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: MEN1; Multiple Endocrine Neoplasia I; Menin 1; Truncated Menin; Menin; MEAI; SCG2
Species:
Human
Source:
E. coli
Cat. No.: HY-P88137A
Synonyms: CHGC; EM66; SgII; SN
Cat. No.: HY-P702089
Purity: ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: MEN1; Multiple Endocrine Neoplasia I; Menin 1; Truncated Menin; Menin; MEAI; SCG2
Species:
Human
Source:
E. coli
Cat. No.: HY-RS08333
Target:
Research Areas:
MEN1 Human Pre-designed siRNA Set A contains three designed siRNAs for MEN1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P702090
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: MEN1; Multiple Endocrine Neoplasia I; Menin 1; Truncated Menin; Menin; MEAI; SCG2
Species:
Human
Source:
E. coli
Cat. No.: HY-189068
CAS No.: 1240895-94-6
GL-4512 is an orally active LILRB4/ILT3 inhibitor with an IC50 of 37 nM against human targets, and human Kd values of 18.1 nM and 39.2 nM, respectively. GL-4512 directly binds to the extracellular pockets of LILRB4/ILT3 that accommodate their ligands, blocks the LILRB4-SCG2 signaling pathway, and inhibits the downstream SHP1/SHP2 and STAT3 signaling pathways. GL-4512 restores anti-tumor immune activity, promotes the production of IFN-γ and IL-2, enhances the activation of cytotoxic T cells, reduces tumor cell viability, inhibits tumor growth, and strengthens intratumoral immune activation. GL-4512 can be used in research related to colorectal cancer and acute myeloid leukemia .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
