21 Results for "

SCaBER

" in MedChemExpress (MCE) Product Catalog:
Products (21)

21 Results for "SCaBER" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-N2491
CAS No.: 29307-03-7
Deoxyelephantopin, a natural bioactive sesquiterpene lactone from Elephantopus scaber, has shown promising anticancer effects against a broad spectrum of cancers. Deoxyelephantopin inhibits NF-κB, MAPK, PI3K/Akt, and β-catenin signaling .
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1
1 Cited Publications
Cat. No.: HY-N2585
CAS No.: 38927-54-7
Isodeoxyelephantopin is a sesquiterpene lactone isolated from Elephantopus scaber. Isodeoxyelephantopin induces ROS generation, suppresses NF-κB activation. Isodeoxyelephantopin also modulates LncRNA expression and exhibit activities against breast cancer .
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Cat. No.: HY-N7432
CAS No.: 15893-52-4
DIMBOA, an antibiotic, has antibacterial properties and inhibits bacteria such as Staphylococcus aureus and the mycotoxin-producing fungus Fusarium graminearum (which causes scab). DIMBOA exhibits strong free radical scavenging activity and weak iron(III) ion reducing activity, and has antioxidant activity. DIMBOA inhibits the biosynthesis and accumulation of toxic trichothecenes by affecting the expression of Tri6 and Tri5. DIMBOA reduces plant susceptibility to scab. DIMBOA also exhibits cytotoxicity to plant cells, causing plasmolysis, cell collapse, and cell rupture .
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Cat. No.: HY-134338
CAS No.: 1314008-27-9
Purity:  99.86%
Research Areas:  

Others

Ipflufenoquin is an insecticide with the potential to control primary infection with apple scab. Ipflufenoquin should be applied between half an inch of green and fruit set .
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Cat. No.: HY-P11211A
Target:  

Bacterial

Research Areas:  

Infection Cancer

D2A21 TFA is an antimicrobial peptide with significant antimicrobial activity against Pseudomonas and bactericidal effect on burn scabs. D2A21 TFA has antitumor activity and can be used in prostate cancer research .
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Cat. No.: HY-P99719
CAS No.: 1640972-00-4
Synonyms: BAY 1129980; Anti-C4.4a antibody-drug conjugates
Research Areas:  

Cancer

Lupartumab Amadotin (BAY 1129980) is an antibody–drug conjugate (ADC) consisting of a fully human C4.4A (LYPD3)-targeting mAb (BAY 1135626) (HY-147281) conjugated to a novel, highly potent derivative of the microtubule-disrupting cytotoxic drug auristatin via a noncleavable alkyl hydrazide linker. Lupartumab Amadotin can be used for the research of non-small cell lung cancer .
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Cat. No.: HY-W020777
CAS No.: 68694-11-1
Research Areas:  

Infection

Triflumizole is one of imidazole fungicides that works by inhibiting ergosterol biosynthesis, and is widely used for the control of powdery mildew and scabs on various fruits and crops .
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Cat. No.: HY-N8448
CAS No.: 114637-83-1
Synonyms: Macroantoin F
3,4-Di-O-caffeoyl quinic acid methyl ester (Macroantoin F) is a dicaffeoyl derivative isolated from the rhizome of Elephantopus scaber Linn. 3,4-Di-O-caffeoyl quinic acid methyl ester exhibited in vitro antiviral activity against respiratory syncytial virus (RSV) with an IC50 value of 0.78 μg/mL .
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Cat. No.: HY-N11546
CAS No.: 30994-75-3
Sapindoside B is a substance with hepatoprotective activity, and also acts as a cytochrome P-450 (cytochrome P-450) inhibitor, antibacterial agent and membrane-disrupting agent. Sapindoside B reversibly inhibits the content of cytochrome P-450 in liver microsomes, suppresses the phenobarbital-induced increase in enzyme content, reduces the production of active metabolites mediated by cytochrome P-450, and alleviates hepatotoxic injury. Sapindoside B binds to Cutibacterium acnes lipase, reduces lipase activity, inhibits biofilm formation, and decreases bacterial adhesion. Sapindoside B exhibits cytotoxicity against human cancer, liver cancer, leukemia and glioblastoma cells. Sapindoside B inhibits mycelial growth of phytopathogenic fungal strains, possesses antibacterial activity against dermatophytes, and also has hemolytic/membrane-lytic activity. Sapindoside B can be used in research related to liver injury, Cutibacterium acnes biofilm-associated infections, gastric cancer, carcinoma, promyelocytic leukemia, glioblastoma, apple scab and grape gray mold .
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Cat. No.: HY-179120
CAS No.: 3095661-21-2
Target:  

Myosin

Research Areas:  

Infection

ZJS178 is a novel inhibitor of myosin I. ZJS178 is a fungicide that has inhibitory activity against Fusarium graminearum and can reduce DON toxin synthesis. ZJS178 can be used for research on plant diseases such as wheat scab .
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Cat. No.: HY-N2596
CAS No.: 439923-16-7
Isoscabertopin is a sesquiterpene lactone isolated from Elephantopus scaber L and shows anti-tumor activities .
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Cat. No.: HY-174390
CAS No.: 3085095-22-0
Research Areas:  

Infection

SDH-IN-29 (Compound A33) is a SDH inhibitor with an IC50 of 0.0709 μM. SDH-IN-29 has a broad spectrum of antifungal activities (EC50s of 0.356, 0.798 and 0.146 μg/mL for Fusarium graminearum, Sclerotinia sclerotiorum, and Rhizoctonia solani, respectively). SDH-IN-29 has moderate to significant protective effects against rice blast, wheat scab and cucumber powdery mildew .
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Cat. No.: HY-W020777R
CAS No.: 68694-11-1
Research Areas:  

Infection

Triflumizole (Standard) is the analytical standard of Triflumizole. This product is intended for research and analytical applications. Triflumizole is one of imidazole fungicides that works by inhibiting ergosterol biosynthesis, and is widely used for the control of powdery mildew and scabs on various fruits and crops .
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Cat. No.: HY-N7432R
CAS No.: 15893-52-4
DIMBOA (Standard) is the analytical standard of DIMBOA. This product is intended for research and analytical applications. DIMBOA, an antibiotic, has antibacterial properties and inhibits bacteria such as Staphylococcus aureus and the mycotoxin-producing fungus Fusarium graminearum (which causes scab). DIMBOA exhibits strong free radical scavenging activity and weak iron(III) ion reducing activity, and has antioxidant activity. DIMBOA inhibits the biosynthesis and accumulation of toxic trichothecenes by affecting the expression of Tri6 and Tri5. DIMBOA reduces plant susceptibility to scab. DIMBOA also exhibits cytotoxicity to plant cells, causing plasmolysis, cell collapse, and cell rupture[1][2][3][4][5].
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Cat. No.: HY-W320538
CAS No.: 46492-08-4
Target:  

Fungal

Research Areas:  

Infection

Benz[g]isoquinoline-5,10-dione, an active component isolated from the ethanolic extract of the aerial parts of Mitracarpus scaber, demonstrates notable in vitro inhibitory activity against AIDS-related pathogens, along with significant antibacterial and antifungal properties, as evidenced by the agar well-diffusion assay.
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Cat. No.: HY-134338R
CAS No.: 1314008-27-9
Research Areas:  

Others

(R)-Omeprazole (sodium) (Standard) is the analytical standard of (R)-Omeprazole (sodium). This product is intended for research and analytical applications. (R)-Omeprazole sodium is a gastric acid resistant compound with activity to inhibit gastric acid secretion. (R)-Omeprazole sodium is metabolized in vivo, and its metabolism is primarily affected by cytochrome P450 enzymes. The interaction between (R)-Omeprazole sodium and mannitol may affect its bioavailability in formulations. (R)-Omeprazole sodium exhibits reversible direct and metabolism-dependent inhibition of CYP2C19 .
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Cat. No.: HY-W725177
CAS No.: 1352994-67-2
Research Areas:  

Infection

Inpyrfluxam is a succinate dehydrogenase (SDH) inhibitor. Inpyrfluxam targets the ubiquinone binding pocket of mitochondrial SDH complex subunits ViSDHB, ViSDHC, ViSDHD, interfering with cellular respiration. Inpyrfluxam inhibits conidial germination and mycelial growth of Venturia inaequalis in vitro. Inpyrfluxam can be used for the research of apple scab .
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Cat. No.: HY-N2767
CAS No.: 104021-39-8
Naphtho[1,2-b]furan, 2-propenoic acid deriv. is a Sesquiterpenoids product that can be isolated from the herbs of Elephantopus scaber .
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Cat. No.: HY-165191
CAS No.: 124495-31-4
Target:  

Fungal

Research Areas:  

Infection

LY214352 is an antifungal agent that targets dihydroorotate dehydrogenase (DHO-DH). LY214352 exhibits antifungal activity against Aspergillus nidulans and agriculturally important ascomycete fungi. LY214352 can be used in studies related to grape gray mold, apple scab, and fungal infections caused by ascomycetes .
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Cat. No.: HY-122480
CAS No.: 366815-39-6
Synonyms: SYP-1620
Research Areas:  

Infection

Fenaminstrobin (SYP-1620) is a strobilurin Fungicide. Fenaminstrobin binds to cytochrome bc1 in the mitochondrial respiratory chain, thereby inhibiting ATP production. Fenaminstrobin exhibits acute toxicity to Daphnia magna. Fenaminstrobin effectively controls diseases such as Fusarium ear rot, downy mildew, rice blast and pear scab .
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