Search Result
Results for "
SN-2
" in MedChemExpress (MCE) Product Catalog:
12
Biochemical Assay Reagents
4
Isotope-Labeled Compounds
| Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
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- HY-P3029
-
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PLA2
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Phospholipase
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Cardiovascular Disease
Inflammation/Immunology
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Phospholipase A2 (PLA2) is a calcium-dependent, heat-stable enzyme that catalyzes the hydrolysis of glycerophospholipids at the sn-2 position of cellular membranes, thereby releasing Arachidonic Acid (AA) (HY-109590). Phospholipase A2 is a key mediator in the biosynthesis of pro-inflammatory lipid mediators, critically involved in inflammatory processes. Phospholipase A2 can be used for cardiovascular and inflammatory diseases research [2] .
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- HY-141571
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Dioleoylphosphatidylglycerol sodium
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Liposome
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Others
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DOPG sodium is a naturally occurring anionic phospholipid, containing oleic acid (18:1) inserted at the sn-1 and sn-2 positions. DOPG can form a lipid bilayer in an aqueous solution and is used in the generation of micelles, liposomes, and other artificial membranes. DOPG also exhibits anti-inflammatory properties .
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- HY-125940
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1,2-Dipalmitoyl-SN-glycero-3-phosphoglycerol sodium
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Liposome
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Others
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DPPG (1,2-Dipalmitoyl-sn-glycero-3-phosphoglycerol sodium) is a phospholipid that contains long-chain (16:0) palmitic acid inserted at the sn-1 and sn-2 positions, and it serves as an active component to prevent BaP molecules from entering the water subphase. DPPG is used to prepare micelles, liposomes, and other types of artificial membranes that can resist damage from UV radiation [2] .
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- HY-16696
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SN 2
5 Publications Verification
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Flavivirus
Dengue Virus
TRP Channel
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Infection
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SN 2 is a potent activator of TRPML3 ion channel with an EC50 of 1.8 μM .
SN 2 also acts as a potent inhibitor of Dengue virus 2 (DENV2) and Zika virus (ZIKV) [2].
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- HY-19997
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TATM
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Biochemical Assay Reagents
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Cancer
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Mannose triflate is a glucose analog. Mannose triflate is a precursor for 18F-FDG synthesis for PET applications. Mannose triflate binds to 18F via SN2 nucleophilic substitution reaction. Mannose triflate can be used for an imaging technique in detection of cancer [2] .
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- HY-W019833
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PC(14:0/18:0); 1-Myristoyl-2-stearoyl-SN-glycero-3-phosphocholine
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Endogenous Metabolite
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Metabolic Disease
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MSPC is an asymmetrical phosphatidylcholine containing a myristic acid (14:0) at the sn-1 position and a stearic acid (18:0) at the sn-2 position. It can self assemble in water to form lipid bilayers. Reagent grade, for research purpose.
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- HY-175067
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DHPI-4,5-P2 sodium salt; PI(4,5)P2 (6:0/6:0) sodium salt; PIP2[4',5'](6:0/6:0) sodium salt
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Biochemical Assay Reagents
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Others
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PtdIns-(4,5)-P2 (1,2-dihexanoyl) (sodium salt) is a synthetic analog of natural Ptdlns with C6:0 fatty acids at the sn-1 and sn-2 positions.
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- HY-P3029A
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PLA2, Crotalus adamanteus Venom
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Phospholipase
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Others
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Phospholipase A2, Crotalus adamanteus Venom (PLA2) catalyzes the hydrolysis of the sn-2 position of membrane glycerophospholipids to liberate arachidonic acid (AA). Phospholipase A2, Crotalus adamanteus Venom is a member of the class of heat-stable, calcium-dependent enzymes, is often used in biochemical studies .
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- HY-W674124
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TG(15:0/15:0/15:0); 1,2,3-Tripentadecanoyl glycerol
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Endogenous Metabolite
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Metabolic Disease
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Tripentadecanoin (TG(15:0/15:0/15:0)) is a triacylglycerol that contains pentadecanoic acid (HY-W004283) at the sn-1, sn-2, and sn-3 positions.
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- HY-W040185
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1,2-DPPA sodium; PA(14:0/14:0) sodium; 1,2-Dimyristoyl-SN-glycero-3-phosphate sodium
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Liposome
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Metabolic Disease
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1,2-Dimyristoyl-sn-glycero-3-phosphate monosodium is a phospholipid containing the long-chain (14:0) myristic acid inserted at the sn-1 and sn-2 positions. It can be used in the generation of micelles, liposomes, and other types of artificial membranes.
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- HY-157697
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18:0p/20:4-PE; C18(Plasm)-20:4-PE; PE(P-18:0/20:4)
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Endogenous Metabolite
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Metabolic Disease
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1-1(Z)-Octadecenyl-2-arachidonoyl-sn-glycero-3-PE (18:0p/20:4-PE; C18(Plasm)-20:4-PE) is a plasmalogen that contains 1(Z)-octadecenoic acid and arachidonic acid (HY-109590) at the sn-1 and sn-2 positions, respectively.
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- HY-141636
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1-Palmitoyl-2-arachidonoyl-SN-glycero-3-phosphocholine; PAPC; PC(16:0/20:4)
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Endogenous Metabolite
Biochemical Assay Reagents
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Cardiovascular Disease
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1-Palmitoyl-2-arachidonoyl-sn-glycero-3-PC (PAPC) is a phospholipid containing palmitic acid (16:0) and arachidonic acid (20:4) at the sn-1 and sn-2 positions, respectively, that is found in biological membranes. PAPC is oxidized in vivo, and its oxidation products are involved in chronic inflammation and vascular disease. PAPC has been used to study signaling of oxidized phospholipids. Levels of PAPC are decreased in isolated human multiple myeloma cells.
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- HY-W440981
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1-Stearoyl-2-palmitoyl-SN-glycero-3-phosphocholine
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Liposome
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Cancer
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SPPC is a phospholipid with different length of fatty acid. The sn-1 position contains a stearic acid (18:0) while the sn-2 position is occupied by a palmitic acid (16:0).
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- HY-W704966
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- HY-W440983
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PC(18:0/22:6); DHA-PC; 1-Stearoyl-2-docosahexaenoyl-SN-glyerco-3-phosphocholine
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PPAR
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Cardiovascular Disease
Cancer
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SDPC (DHA-PC) is a new generation of omega-3 lipids, which contains an ester bond linking DHA at the sn-2 position of phospholipid. 1-Stearoyl-2-docosahexaenoyl-sn-glyerco-3-phosphocholine exerts anti-angiogenesis effect through activating PPARγ. 1-Stearoyl-2-docosahexaenoyl-sn-glyerco-3-phosphocholine significantly declines the proliferation, migration, tube formation of human umbilical vein endothelial cells. 1-Stearoyl-2-docosahexaenoyl-sn-glyerco-3-phosphocholine has the potential for anti-tumor angiogenesis research .
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- HY-W800805
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Liposome
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Cancer
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DOPE-Mal is a synthetic analog of naturally-occurring PE containing 18:1 fatty acids at the sn-1 and sn-2 positions with a terminal maliemide group. The maleimide group will react with a thiol group to form a covalent bond. The hydrophilic PEG spacer increases solubility in aqueous media.
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- HY-W583869
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1-Stearoyl-2-Oleoyl-SN-glycero-3-PE; 18:0-18:1 PE; PE(18:0/18:1)
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Liposome
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Metabolic Disease
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1-Stearoyl-2-oleoyl-sn-glycerol-3-phosphoethanolamine is a phospholipids that contains stearic acid and oleic acid at the sn-1 and sn-2 positions, respectively. It has been used in the generation of lipid nanoparticles (LNPs) for in vitro delivery of mRNA or nuclear-targeted plasmid DNA.
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- HY-131652
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16:0 Diether PC
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Liposome
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Metabolic Disease
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1,2-Di-O-hexadecyl-sn-glycero-3-phosphocholine (16:0 Diether PC) is a synthetic ether-linked phospholipid containing hexadecyl groups at the sn-1 and sn-2 positions. It is commonly used in the generation of liposomes and artificial membranes to study membrane dynamics.
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- HY-157698
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C18(plasm)-20:4-PC; 18:0p/20:4-PC; PC(P-18:0/20:4)
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Endogenous Metabolite
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Metabolic Disease
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1-1(Z)-Octadecenyl-2-arachidonoyl-sn-glycero-3-PC is a plasmalogen that contains 1(Z)-octadecenoic acid and arachidonic acid (HY-109590) at the sn-1 and sn-2 positions, respectively. It scavenges singlet oxygen in a cell-free assay.
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- HY-145384
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Phospholipase
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Inflammation/Immunology
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ROC-0929 (compound 13a) is a potent and selective inhibitor of secreted phospholipases A2 (sPLA2s) with an IC50 of 80 nM, specially targeting hGX. ROC-0929 inhibits the phosphorylation of ERK1/2 and p-38. Secreted phospholipases A2 (sPLA2s) are a family of disulfide-rich, Ca 2+-dependent enzymes that hydrolyze the sn-2 position of glycero-phospholipids to release a fatty acid and a lysophospholipid. ROC-0929 has the potential for researching inflammation related diseases .
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- HY-W440958
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PSPC; PC(16:0-18:0)
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Liposome
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Cancer
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1-Palmitoyl-2-stearoyl-sn-glycero-3-phosphocholine is an assymetrical phospholipid containing saturated palmitic and stearic acid at the sn-1 and sn-2 position respectively. The phosphate group is attached to choline.
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- HY-134154
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PAzePC; Azelaoyl PC; 1-Palmitoyl-2-Azelaoyl PC
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Endogenous Metabolite
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Metabolic Disease
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Oxidized low-density lipoprotein (oxLDL) particles contain low molecular weight species which are cytotoxic and pro-atherogenic. Many of these substances were isolated and purified from oxLDL and identified as phosphatidylcholine species containing a fragmented, oxidized short-chain fatty acid remnant at the sn-2 position. PAz-PC (Azelaoyl PC) is one of the predominant oxLDL species and may be one of the important structural determinants of oxLDL.
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- HY-P10053
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Phospholipase
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Metabolic Disease
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sPLA2-IIA Inhibitor is a cyclic pentapeptide analog of FLSYK (cyclic 2-Nal-Leu-Ser-2-Nal-Arg (c2)), that binds to hGIIA (human IIA phospholipase A2) and inhibits its hydrolytic ability. sPLA2 is a member of the esterase superfamily that catalyzes the hydrolysis of the ester bond at the sn-2 position of glycerophospholipids, releasing free fatty acids such as arachidonic acid and lysophospholipids .
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- HY-W127380
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Biochemical Assay Reagents
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Others
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Arachidonoyl Thio-PC is a substrate of many phospholipase A2 (PLA2), including sPLA2, cPLA2 and iPLA2. Cleavage of sn-2 fatty acids by PLA2 results in the production of free thiols, which react with chromogenic reagents such as DTNB (Ellman's reagent) and DTP, allowing quantification of PLA2 activity. Isozyme-specific cPLA2 activity can be measured by depleting or inhibiting sPLA2 and iPLA2 activity in the assay.
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- HY-N7953
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Endogenous Metabolite
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Metabolic Disease
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1,2-Dioleoyl-3-linoleoyl-rac-glycerol (OOL) is a triacylglycerol containing oleic acid at the sn-1 and sn-2 positions and linoleic acid at the sn-3 position. It is found in a variety of seed and vegetable oils, including pumpkin seed, olive, and sesame oils.
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- HY-141614
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Phosphatidylcholine Diarachidoyl; 1,2-DAPC; L-α-Diarachidonoyl lecithin
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Liposome
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Metabolic Disease
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1,2-Diarachidoyl-sn-glycero-3-phosphocholine (1,2-DAPC) is a phospholipid containing the saturated long-chain (20:0) arachidic acid inserted at the sn-1 and sn-2 positions. It can be used in the generation of micelles, liposomes, and other types of artificial membranes.
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- HY-W343736
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1,3-DPPE; 1,3-Dipalmitoyl-SN-glycero-2-PE
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Liposome
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Cancer
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1,3-Dipalmitoyl-glycero-2-phosphoethanolamine is a phospholipid containing the saturated long-chain (16:0) stearic acid inserted at the sn-1 and sn-3 positions and PE at the sn-2 site. It can be used in the generation of micelles, liposomes, and other types of artificial membranes.
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- HY-117168
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Endogenous Metabolite
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Metabolic Disease
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1,2-Dilinoleoyl-sn-glycerol is a diacylglycerol (DAG) with linoleic acid (HY-N0729) (18:2) side chains attached at both the sn-1 and sn-2 positions . 1,2-Dilinoleoyl-sn-glycerol can be prepared from L-dilinoleoylphosphatidylcholine via hydrolysis with phospholipase C [2] .
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- HY-W440982A
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(Rac)-PC(18:0/18:1); (Rac)-2-Oleoyl-1-stearoyl-SN-glycero-3-phosphocholine
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Liposome
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Others
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(Rac)-SOPC ((Rac)-PC(18:0/18:1)) ((Rac)-2-Oleoyl-1-stearoyl-sn-glycero-3-phosphocholine) is the racemate of SOPC (HY-W440982). SOPC is an asymmetrical phospholipid with saturated fatty acid (stearic acid/18:0) at sn-1 position and unsaturated fatty acid (oleic acid/18:1) at sn-2 position. SOPC can stabilize the outer segment membrane of frog rods .
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- HY-141642
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Glycerol triheptadecanoate; Trimargarin
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Biochemical Assay Reagents
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Others
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Triheptadecanoin is a triacylglycerol that contains heptadecanoic acid at the sn-1, sn-2, and sn-3 positions .
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- HY-W440957
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PC(16:0/14:0); 1-palmitoyl-2-myristoyl-SN-glycero-3-phosphocholine
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Liposome
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Cancer
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PMPC is a phosphatidylcholine with asymmetrical fatty acid. Palmitic acid occupies sn-1 position while myristic acid is placed at the sn-2 position.
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- HY-W800733
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1,2-Dilauroyl-SN-glycero-3-phosphorylglycerol; PG(12:0/12:0)
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Liposome
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Cancer
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DLPG is a phospholipid containing lauric acid (12 chain fatty acid) inserted at the sn-1 and sn-2 positions. Its phosphate group is attached to glycerol. It is used in the generation of micelles, liposomes, and other artificial membranes.
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- HY-W590536
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1-Palmitoyl-2-Lauroyl-SN-glycero-3-Phosphatidylcholine; 1-Palmitoyl-2-Lauroyl-SN-glycero-3-Phosphocholine
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Liposome
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Cancer
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1,2-PLPC is a phospholipid containing palmitoyl (16:0) and lauryl (12:0) acyl substituents at the sn-1 and sn-2 positions, respectively. It can be used in the generation of micelles, liposomes, and other types of artificial membranes.
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- HY-175120
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1,2,3-Tri-10(Z)-pentadecenoyl glycerol
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Biochemical Assay Reagents
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Others
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Tri-10(Z)-pentadecenoin (1,2,3-Tri-10(Z)-pentadecenoyl glycerol) is a triacylglycerol that contains 10(Z)-pentadecenoic acid at the sn-1, sn-2, and sn-3 positions.
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- HY-113925
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1,2-DLPA Sodium; (2R)-2,3-bis(dodecanoyloxy)propyl hydrogen phosphate sodium
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Liposome
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Metabolic Disease
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1,2-Dilauroyl-sn-glycero-3-phosphate (1,2-DLPA) sodium is a phospholipid containing the medium-chain (12:0) lauric acid inserted at the sn-1 and sn-2 positions. It can be used in the generation of micelles, liposomes, and other types of artificial membranes.
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- HY-W713925
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Endogenous Metabolite
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Metabolic Disease
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Diheptanoyl Thio-PC is a substrate for all phospholipase A2s (PLA2s) with the exception of cPLA2 and PAF-acetyl hydrolase (PAF-AH).1 Interaction of this compound with a PLA2 results in cleavage of the sn-2 fatty acid generating a free thiol on the lysophospholipid. This free thiol can be detected using chromogenic substrates such as DTNB (Ellman’s reagent) and DTP.
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- HY-W643167
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Glycerol Tritridecanoyl; 13:0 TAG; 13:0/13:0/13:0-TG
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Biochemical Assay Reagents
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Infection
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1,2,3-Tritridecanoyl glycerol is a synthetic triacylglycerol that contains tridecanoic acid in the sn-1, sn-2, and sn-3 positions. It has been used as a standard for the relative quantification of triacylglycerols in C. elegans fat stores. It has also been used as an internal standard for the quantification of triacylglycerols in the serum and liver of adult rat offspring receiving dietary conjugated linoleic acids during and after gestation.
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- HY-W127408
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Biochemical Assay Reagents
Endogenous Metabolite
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Others
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1,2,3-Tripalmitoleoyl-rac-glycerol is a triacylglycerol containing palmitoleic acid at the sn-1, sn-2 and sn-3 positions. It reduces erythrocyte deformability in a concentration-dependent manner in the Reid filtration assay. Hepatic levels of 1,2,3-tripalmitoleoyl-rac-glycerol are increased in a JAK2L mouse model of hepatic steatosis. 1,2,3-Tripalmitoleoyl-rac-glycerol plasma levels are reduced in patients with predialysis renal disease.
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- HY-157742
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Biochemical Assay Reagents
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Others
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1,3-Dioleoyl-2-elaidoyl glycerol (OEO) is a triacylglycerol. 1,3-Dioleoyl-2-elaidoyl glycerol can be used for the research of the effects of unsaturation and sn-2 substitution on the polymorphic behavior of triacylglycerols .
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- HY-157741
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Lipase
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Others
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1-Myristoyl-2-oleoyl-3-palmitoyl-rac-glycerol (MOP) is a triacylglycerol containing myristic acid (HY-N2041), oleic acid (HY-N1446) and palmitic acid (HY-N0830) at the sn-1, sn-2 and sn-3 positions, respectively .
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- HY-N7859
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1,3-Dioleoyl-2-myristoyl-rac-glycerol
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Lipase
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Others
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1,3-Dioleoyl-2-myristoyl glycerol is a triacylglycerol that contains oleic acid at the sn-1 and sn-3 positions and myristic acid at the sn-2 position .
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- HY-176085
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Phospholipase
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Others
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Heptanoyl thio-PC is a sn-2 thiol-labeled Phospholipase A2 (HY-P3029) (PLA2) substrate that can be used to detect the activity of Phospholipase A2 .
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- HY-125744
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Biochemical Assay Reagents
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Others
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Palmitoyl thio-PC is a chromogenic substrate specific for PLA2 with a palmitoyl thioester at the sn-2 position. Palmitoyl thio-PC could be used to measure bee-venom sPLA2 activity in a phospholipid system .
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- HY-W725327
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1,2-Dipropionyl-SN-glycero-3-Phosphatidylcholine; 1,2-Dipropionyl-SN-glycero-3-Phosphocholine; PC(3:0/3:0)
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Endogenous Metabolite
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Metabolic Disease
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1,2-Dipropionyl-sn-glycero-3-PC is a phospholipid containing propionic acid at the sn-1 and sn-2 positions. It has been used to study the interaction between water and the phosphocholine headgroup in aqueous solutions.
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- HY-170631
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Biochemical Assay Reagents
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Metabolic Disease
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1,2-Dielaidoyl-3-palmitoyl-rac-glycerol is a triacylglycerol that contains Elaidic acid (HY-113016) in the sn-1 and sn-2 positions and Palmitic acid (HY-N0830) in the sn-3 position.
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- HY-W777866
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Biochemical Assay Reagents
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Others
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(Rac)-1-Linoleoyl-2-stearoyl-3-chloropropanediol is a diacylglycerol that contains Linoleic acid at the sn-1 position and stearic acid group at the sn-2 position. The chlorine is a good leaving group and can undergo substitution reactions.
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- HY-145541
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1,2-Dinonadecanoin
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Biochemical Assay Reagents
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Others
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12-Dinonadecanoyl-rac-glycerol is a diacylglycerol containing nonadecanoic acid (HY-W004261) at the sn-1 and sn-2 positions. Nonadecanoic acid is a 19-carbon long saturated fatty acid. Nonadecanoic acid is the major constituent of the substance secreted by Rhinotermes marginalis to defence .
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- HY-157683
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Biochemical Assay Reagents
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Others
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16:0-18:1 Diether PG is a type of glycerophospholipids, in which the hexadecane and octadecene chains are connected to the sn-1 and sn-2 positions of the glycerol backbone via ether bonds, respectively. 16:0-18:1 Diether PG can be used to prepare liposomes .
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- HY-125940S
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1,2-Dipalmitoyl-SN-glycero-3-phosphoglycerol-d62 sodium
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Isotope-Labeled Compounds
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Others
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DPPG-d62 (sodium) is deuterium labeled DPPG. DPPG sodium (1,2-Dipalmitoyl-sn-glycero-3-PG sodium) is a phospholipid containing the long-chain(16:0) palmitic acid inserted at the sn-1 and sn-2 positions. DPPG sodium is used in the generation of micelles, l
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- HY-168372
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Phospholipase
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Metabolic Disease
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1-Myristoyl-2-Linoleoyl-sn-glycero-3-PC is a phospholipid that contains Myristic acid (HY-N2041) and Linoleic acid (HY-N0729) at the sn-1 and sn-2 positions, respectively, which is found in human plasma .
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- HY-142974
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1,2-Olein-3-Docosohexaenoin; 18:1/18:1/22:6-TG; C1OO
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Endogenous Metabolite
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Metabolic Disease
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1,2-Dioleoyl-3-docosohexaenoyl-rac-glycerol is a triacylglycerol that contains oleic acid (HY-N1446) at the sn-1 and sn-2 positions and docosahexaenoic acid (HY-B2167) at the sn-3 position. It has been detected in human breast milk.
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- HY-W710380
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1,2-Stearin-3-Olein; TG(18:0/18:0/18:1)
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Endogenous Metabolite
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Metabolic Disease
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1,2-Distearoyl-3-oleoyl-rac-glycerol is a triacylglycerol that contains stearic acid (HY-B2219) at the sn-1 and sn-2 positions and oleic acid (HY-N1446) at the sn-3 position. It has been found in cocoa butter and vegetable oils.
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- HY-134174
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Liposome
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Cancer
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1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphate is a phospholipid containing saturated palmitic acid (16:0) and monounsaturated oleic acid (18:1) inserted at the sn-1 and sn-2 positions, respectively. It can be used in the generation of micelles, liposomes, and other types of artificial membranes.
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- HY-168386
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Endogenous Metabolite
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Others
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1,2-Dipalmitoyl-3-Myristoyl-rac-glycerol is a triacylglycerol in which palmitic acid (HY-N0830) is located at the sn-1 and sn-2 positions, and myristic acid (HY-N2041) is at the sn-3 position. It can be found in bovine milk fat .
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- HY-170634
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Biochemical Assay Reagents
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Metabolic Disease
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1-Stearoyl-2-linoleoyl-3-oleoyl-rac-glycerol is a triacylglycerol that contains Stearic acid (HY-B2219), Linoleic acid (HY-N0729), and Oleic acid (HY-N1446) at the sn-1, sn-2, and sn--3 positions, respectively.
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- HY-W800734
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MPPC; PC(14:0/16:0)
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Liposome
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Cancer
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1-Myristoyl-2-palmitoyl-sn-glycero-3-phosphocholine (MPPC) is an asymmetrical phosphatidylcholine containing a myristic acid (14:0) at the sn-1 position and a palmitic acid (16:0) at the sn-2 position. It is commonly used in the generation of micelles, liposomes, and other types of artificial membranes.
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- HY-168391
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Biochemical Assay Reagents
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Others
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1-Lauroyl-2-oleoyl-3-palmitoyl-rac-glycerol is a triacylglycerol with Lauric acid (HY-Y0366), Oleic acid (HY-N1446), and Palmitic acid (HY-N0830) at the sn-1, sn-2 and sn-3 positions, respectively .
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- HY-W339206
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Endogenous Metabolite
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Others
|
|
1,2-Dinonanoyl-sn-glycero-3-phosphocholine, a specific phosphatidylcholine, features fatty acyl configurations that can influence the physical properties of membranes, making it a key component for generating eicosanoids. As a phospholipid abundant in membranes, it has fatty acids attached to glycerol at the sn-1 and sn-2 positions via ester bonds.
|
-
- HY-W704603
-
|
1,2-Olein-3-Stearin; TG(18:1/18:1/18:0)
|
Endogenous Metabolite
|
Metabolic Disease
|
|
1,2-Dioleoyl-3-stearoyl-rac-glycerol is a triacylglycerol that contains oleic acid (HY-N1446) at the sn-1 and sn-2 positions and stearic acid (HY-B2219) at the sn-3 position. It has been found in sunflower, corn, and soybean oils, as well as ostrich oil.
|
-
- HY-175069
-
|
PA(18:1/18:1) ammonium salt; 1,2-DOPA ammonium salt
|
Liposome
|
Others
|
|
1,2-Dioleoyl-sn-glycero-3-PA (ammonium salt) is a phospholipid with long-chain fatty acid oleic acid inserted at the sn-1 and sn-2 positions. 1,2-Dioleoyl-sn-glycero-3-PA (ammonium salt) can be used to synthsize artificial membranes such as liposomes [2].
|
-
- HY-145522
-
|
MEM; 1,3-Myristin-2-Eicosapentaenoin; 14:0/20:5/14:0-TG
|
Biochemical Assay Reagents
|
Metabolic Disease
|
|
1,3-Dimyristoyl-2-eicosapentaenoyl glycerol (MEM) is a triacylglycerol that contains myristic acid (HY-N2041) at the sn-1 and sn-3 positions and eicosapentaenoic acid at the sn-2 position. The myristoyl groups in MEM do not affect the oxidative stability of eicosapentaenoic acid (EPA) during long-term storage at 25°C.
|
-
- HY-W706672
-
|
Glycerol Tritricosanoate; TG(23:0/23:0/23:0); Tritricosanoin
|
Endogenous Metabolite
|
Metabolic Disease
|
|
1,2,3-Tritricosanoyl glycerol is a triacylglycerol that contains tricosanoic acid (HY-W009081) at the sn-1, sn-2, and sn-3 positions. It has been used as an internal standard for the quantification of fatty acids in the triglyceride component of human aortic endothelial cells (HAECs) grown in media supplemented with stearic and/or oleic acid.
|
-
- HY-169036
-
-
- HY-142971
-
|
1-Myristin-2-Linolein-3-Olein; TG(14:0/18:2/18:1)
|
Endogenous Metabolite
|
Metabolic Disease
|
|
1-Myristoyl-2-linoleoyl-3-oleoyl-rac-glycerol is a triacylglycerol that contains myristic acid (HY-N2041), linoleic acid (HY-N0729), and oleic acid (HY-N1446) at the sn-1, sn-2, and sn-3 positions, respectively. It has been found in mature human milk, infant formula fats, and butterfat.
|
-
- HY-168780
-
|
|
Endogenous Metabolite
|
Others
|
|
1-Palmitoyl-2-arachidoyl-3-oleoyl-rac-glycerol is a triacylglycerol. 1-Palmitoyl-2-arachidoyl-3-oleoyl-rac-glycerol contains Palmitic acid (HY-N0830), Arachidonic acid (HY-109590), and Oleic acid (HY-N1446) at sn-1, sn-2, and sn-3 locations, respectively .
|
-
- HY-145545
-
|
PE(18:0/22:4); 1-Stearoyl-2-Docosatraenoyl-SN-glycero-3-PE
|
Endogenous Metabolite
|
Metabolic Disease
|
|
1-Stearoyl-2-adrenoyl-sn-glycero-3-PE is a phospholipid that contains stearic acid (HY-B2219) and adrenic acid (HY-W013215) at the sn-1 and sn-2 positions, respectively. 1-Stearoyl-2-adrenoyl-sn-glycero-3-PE levels are inversely correlated with subject age in mitochondria isolated from human post-mortem hippocampus.
|
-
- HY-161948
-
|
|
Ferroptosis
|
Cancer
|
|
Ferroptosis inducer-4 (Compound 5) is a ferroptosis (Ferroptosis) inducer with a structure featuring terminal double bonds introduced at the sn-2 position of phospholipids. Ferroptosis inducer-4 exhibits significant cytotoxicity towards HT-1080 cells, with an IC50 of 18 μM. This cytotoxic mechanism involves the generation of lipid peroxides and oxidative damage to the cell membrane triggered by the terminal double bonds. Ferroptosis inducer-4 can be used for research on ferroptosis regulation .
|
-
- HY-W699318
-
|
|
Reactive Oxygen Species (ROS)
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Others
|
|
1-Oleoyl-2-palmitoylglycerol is a diacylglycerol in which an oleic acid and a palmitic acid are attached to sn-1 and sn-2 position. 1-Oleoyl-2-palmitoylglycerol enhances the inhibition of superoxide anion production induced by fMLF/cytochalasin B (CB) in human neutrophils. 1-Oleoyl-2-palmitoylglycerol can be used in research about lipid metabolism, membrane fluidity, or the distribution and function of lipids in cells [2].
|
-
- HY-168393
-
|
1,3-Palmitin-2-stearin
|
Endogenous Metabolite
|
Metabolic Disease
|
|
1,3-Dipalmitoyl-2-stearoyl glycerol (1,3-Palmitin-2-stearin) is a triacylglycerol in which palmitic acid (HY-N0830) is located at the sn-1 and sn-3 positions, and stearic acid (HY-B2219) is at the sn-2 position. The levels of 1,3-Dipalmitoyl-2-stearoyl glycerol are associated with energy depletion caused by reduced food intake in rats .
|
-
- HY-168394
-
|
1,2-Palmitin-3-stearin
|
Endogenous Metabolite
|
Others
|
|
1,2-Dipalmitoyl-3-stearoyl-rac-glycerol (1,2-Palmitin-3-stearin) is a triacylglycerol found in ostrich and emu oils as well as cow milk fat. The sn-1 and sn-2 positions of 1,2-Dipalmitoyl-3-stearoyl-rac-glycerol contain palmitic acid (HY-N0830), and the sn-3 position contains stearic acid (HY-B2219) [2].
|
-
- HY-149545
-
|
1,3-Dipalmitoyl-2-docosahexaenoyl glycerol
|
Carnitine Palmitoyltransferase (CPT)
Fatty Acid Synthase (FASN)
|
Metabolic Disease
|
|
1,3-Palmitin-2-docosahexaenoin (1,3-Dipalmitoyl-2-docosahexaenoyl glycerol) is the isomer of triacylglycerol (TAG), in which docosahexaenoic acid (DHA) is located at the β position (sn-2) of the glycerol backbone. 1,3-Palmitin-2-docosahexaenoin inhibits fatty acid synthase and cholesterol metabolism enzymes, activates carnitine palmitoyltransferase (CPT) in liver mitochondria and promotes β-oxidation of fatty acids. 1,3-Palmitin-2-docosahexaenoin exhibits lipid metabolism regulating activity .
|
-
- HY-170639
-
|
|
Others
|
Metabolic Disease
|
|
1,2-Diheptadecanoyl-rac-glycerol is a diacylglycerol that contains Heptadecanoic acid (HY-W004284) at the sn-1 and sn-2 positions.
|
-
- HY-168797
-
-
- HY-170632
-
|
1,2,3-Tri-6(Z)-octadecenoyl glycerol
|
Biochemical Assay Reagents
|
Metabolic Disease
|
|
Tripetroselinin (1,2,3-Tri-6(Z)-octadecenoyl glycerol) is a triacylglycerol that contains Petroselinic acid (HY-113362) at the sn-1, sn-2, and sn-3 positions.
|
-
- HY-170625
-
-
- HY-165107
-
|
1,2-Caprylin-3-stearin; 1,2-Octanoin-3-stearin; TG(8:0/8:0/18:0)
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Others
|
Others
|
|
1,2-Dioctanoyl-3-stearoyl-rac-glycerol is a triacylglycerol that contains octanoic acid at the sn-1 and sn-2 positions and stearic acid at the sn-3 position. It has been found in French butterfat.
|
-
- HY-170636
-
-
- HY-175110
-
|
|
Drug Derivative
|
Others
|
|
1,3-Dipalmitoyl-2-arachidonoyl-sn-glycerol is a triacylglycerol containing Palmitic acid (HY-N0830) at the sn-1 and sn-3 positions and Arachidonic acid (HY-109590) at the sn-2 position.
|
-
- HY-170681
-
|
|
Biochemical Assay Reagents
|
Metabolic Disease
|
|
1,3-Didocosanoyl-2-oleoyl glycerol is a triacylglycerol that contains Docosanoic acid (HY-W013049) at the sn-1 and sn-3 positions and Oleic acid (HY-N1446) at the sn-2 position.
|
-
- HY-170676
-
|
|
Biochemical Assay Reagents
|
Metabolic Disease
|
|
1,3-Dilinoleoyl-2-docosahexaenoyl glycerol is a triacylglycerol that contains Linoleic acid (HY-N0729) at the sn-1 and sn-3 positions and Docosahexaenoic acid (HY-B2167) at the sn-2 position.
|
-
- HY-170633
-
|
|
Biochemical Assay Reagents
|
Metabolic Disease
|
|
1,2-Dielaidoyl-3-stearoyl-rac-glycerol is a triacylglycerol that contains Elaidic acid (HY-113016) at the sn-1 and sn-2 positions and Stearic acid (HY-B2219) at the sn-3 position.
|
-
- HY-170680
-
|
|
Biochemical Assay Reagents
|
Metabolic Disease
|
|
1,2-Dilinoleoyl-3-stearoyl-rac-glycerol is a triacylglycerol that contains Linoleic acid (HY-N0729) at the sn-1 and sn-2 positions and Stearic acid (HY-B2219) at the sn-3 position.
|
-
- HY-W482407
-
|
(S)-2,3-Bis(hexadecyloxy)propan-1-ol
|
Biochemical Assay Reagents
|
Metabolic Disease
|
|
1,2-O-Dihexadecyl-sn-glycerol ((S)-2,3-Bis(hexadecyloxy)propan-1-ol) is a saturated dialkyl glyceryl ether with hexadecyl groups at the sn-1 and sn-2 positions that mimics the structure of diacylglycerol.
|
-
- HY-175113
-
|
|
Liposome
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Others
|
|
1-1(Z)-Octadecenyl-2-adrenoyl-sn-glycero-3-PC is a plasmalogen that contains 1(Z)-octadecenoic acid and adrenic acid (HY-W013215) at the sn-1 and sn-2 positions, respectively .
|
-
- HY-W702728
-
|
|
Biochemical Assay Reagents
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Others
|
|
rac 1-Palmitoyl-2-chloropropanediol is a monoacylglycerol of palmitic acid at the sn-1 position and a chloride group at the sn-2 position. The hydroxyl group enables further derivatization or replacement with other reactive functional groups. The chlorine is a good leaving group and can undergo substitution reactions.
|
-
- HY-168796
-
|
|
Biochemical Assay Reagents
|
Metabolic Disease
|
|
1-Palmitoyl-2-13(S)-HpODE-sn-glycero-3-PC is a phospholipid that contains Palmitic acid (HY-N0830) and 13(S)-HpODE (HY-110406) at the sn-1 and sn-2 positions, respectively.
|
-
- HY-168390
-
|
1-Stearin-2,3-linolein
|
Endogenous Metabolite
|
Others
|
|
1,2-Stearin-3-linolein is a triacylglycerol. 1,2-Stearin-3-linolein has Stearic acid (HY-B2219) at sn-1 and sn-2 positions, and contains Linoleic acid (HY-N0729) at sn-3 position.
|
-
- HY-P3029C
-
|
|
Phospholipase
|
Metabolic Disease
|
|
Phospholipase A2, Porcine (EC 3.1.1.4) hydrolyzes the β-ester bond of zwitterionic glycerophospholipids. Preferred substrates are phosphatidylcholine, phosphatidylethanolamine, and their plasmalogen analogues. Phosphatidylinositol and phosphatidylserine are also hydrolyzed. Phospholipase A2specifically recognizes the sn-2 acyl bond of phospholipids and catalytically hydrolyzes the bond releasing arachidonic acid and lysophospholipids.
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-
- HY-175111
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|
|
Liposome
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Others
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|
1-Stearoyl-2-17(S)-HDoTE-sn-glycero-3-PC is a phospholipid that contains stearic acid (HY-B2219) and the oxidized adrenic acid metabolite 17(S)-HDoTE (HY-168774) at the sn-1 and sn-2 positions, respectively .
|
-
- HY-P3029B
-
|
|
Phospholipase
|
Metabolic Disease
|
|
Phospholipase A2, Streptomyces violaceoruber (EC 3.1.1.4) hydrolyzes the β-ester bond of zwitterionic glycerophospholipids. Preferred substrates are phosphatidylcholine, phosphatidylethanolamine, and their plasmalogen analogues. Phosphatidylinositol and phosphatidylserine are also hydrolyzed. Phospholipase A2specifically recognizes the sn-2 acyl bond of phospholipids and catalytically hydrolyzes the bond releasing arachidonic acid and lysophospholipids.
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-
- HY-W704597
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|
1-Palmitin-2-Olein-3-Stearin; TG(16:0/18:1/18:0)
|
Endogenous Metabolite
|
Metabolic Disease
|
|
1-Palmitoyl-2-oleoyl-3-stearoyl-rac-glycerol is a triacylglycerol that contains palmitic acid (HY-N0830) at the sn-1 position, oleic acid (HY-N1446) at the sn-2 position, and stearic acid (HY-B2219) at the sn-3 position. It is one of the primary triacylglycerols found in cocoa butter.
|
-
- HY-172742
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|
|
Biochemical Assay Reagents
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Others
|
|
Dioctanoyl PI(3,4)P2 (sodium) is a synthetic analog of natural Ptdlns featuring C8:0 fatty acids at the sn-1 and sn-2 positions. Dioctanoyl PI(3,4)P2 (sodium) contains the same inositol and diacylglycerol (DAG) stereochemistry as the natural Ptdlns .
|
-
- HY-170623
-
|
|
Biochemical Assay Reagents
|
Metabolic Disease
|
|
1-Palmitoyl-2-stearoyl-3-butyryl-rac-glycerol is a triacylglycerol containing Palmitic acid (HY-N0830), Stearic acid (HY-B2219), and Butyric acid (HY-B0350) at the sn-1, sn-2, and sn-3 positions, respectively. It has been used to determine the stereospecificity and typoselectivity of lipases.1
|
-
- HY-170466
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|
1-Palmitoyl-2-stearoyl-(12-doxyl)-SN-glycero-3-phosphocholine
|
Biochemical Assay Reagents
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Others
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|
16:0-12 Doxyl PC (1-Palmitoyl-2-stearoyl-(12-doxyl)-sn-glycero-3-phosphocholine) is a fluorescence quencher, and its nitrogen oxide is located downstream of the sn-2 chain. 16:0-12 Doxyl PC has a better fluorescence quenching effect onthe fluorophore is buried within the hydrocarbon interior of the bilayer .
|
-
- HY-165093
-
|
1-Arachidin-2-olein-3-palmitin; TG(20:0/18:1/16:0)
|
Others
|
Others
|
|
1-Arachidoyl-2-oleoyl-3-palmitoyl-rac-glycerol (1-Arachidin-2-olein-3-palmitin) is a triglyceride characterized by regioisomerism by silver ion HPLC/MS. The method can be applied to the analysis of complex samples of vegetable oils and animal fats, and the results show that plant and animal fats have different preferences for fatty acid occupancy at the sn-2 position.
|
-
- HY-W710440
-
|
1,2-Stearin-3-palmitin; TG(18:0/18:0/16:0)
|
Endogenous Metabolite
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Others
|
|
1,2-Distearoyl-3-palmitoyl-rac-glycerol is a triglyceride found in cocoa butter, lard, and cod liver oil. 1,2-Distearoyl-3-palmitoyl-rac-glycerol is formed by combining the glycerol skeleton with Stearic acid (HY-B2219) (sn-1 and sn-2 positions) and Palmitic acid (sn-3 positions) (HY-N0830) [2].
|
-
- HY-175115
-
|
|
Liposome
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Others
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|
1-Stearoyl-2-17(S)-HDoTE-sn-glycero-3-PE is a phospholipid. 1-Stearoyl-2-17(S)-HDoTE-sn-glycero-3-PE contains Stearic acid (HY-B2219) and the oxidized adrenic acid metabolite 17(S)-HDoTE (HY-168774) at the sn-1 and sn-2 positions, respectively.
|
-
- HY-W590574
-
|
|
Biochemical Assay Reagents
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Others
|
|
Propargyl-PEG4-Ms has an alkyne group and a mesylate group. The mesylate group is a sulfonate ester for nucleophilic substitution reactions (SN2). The alkyne group can react with azides via copper catalyzed Click Chemistry reactions. The PEG units help increase the solubility of the molecule in aqueous environments.
|
-
- HY-W010667
-
|
1,3-Dipalmitoyl-2-oleoylglycerol; ?1,3-Palmitin-2-Olein; TG(16:0/18:1/16:0)
|
Endogenous Metabolite
|
Metabolic Disease
|
|
1,3-Dipalmitoyl-2-oleoyl glycerol (1,3-Palmitin-2-Olein; TG(16:0/18:1/16:0)) is a triacylglycerol that contains palmitic acid (HY-N0830) at the sn-1 and sn-3 positions and oleic acid (HY-N1446) at the sn-2 position. It has been found in cocoa butter, Chinese tallow butter, and the palm stearin fraction of palm oil.
|
-
- HY-W710512
-
|
Glycerol Tritricosanoate-d5; TG(23:0/23:0/23:0)-d5; Tritricosanoin-d5
|
Isotope-Labeled Compounds
Endogenous Metabolite
|
Metabolic Disease
|
|
Propane-1,2,3-triyl tritricosanoate-d5 (Glycerol Tritricosanoate-d5) is deuterium labeled Propane-1,2,3-triyl tritricosanoate. 1,2,3-Tritricosanoyl glycerol is a triacylglycerol that contains tricosanoic acid (HY-W009081) at the sn-1, sn-2, and sn-3 positions. It has been used as an internal standard for the quantification of fatty acids in the triglyceride component of human aortic endothelial cells (HAECs) grown in media supplemented with stearic and/or oleic acid.
|
-
- HY-W706672R
-
|
Glycerol Tritricosanoate (Standard); TG(23:0/23:0/23:0) (Standard); Tritricosanoin (Standard)
|
Endogenous Metabolite
Reference Standards
|
Metabolic Disease
|
|
Propane-1,2,3-triyl tritricosanoate (Standard) is the analytical standard of Propane-1,2,3-triyl tritricosanoate. This product is intended for research and analytical applications. 1,2,3-Tritricosanoyl glycerol is a triacylglycerol that contains tricosanoic acid (HY-W009081) at the sn-1, sn-2, and sn-3 positions. It has been used as an internal standard for the quantification of fatty acids in the triglyceride component of human aortic endothelial cells (HAECs) grown in media supplemented with stearic and/or oleic acid.
|
-
- HY-W339834
-
|
|
Acyltransferase
Endogenous Metabolite
Liposome
|
Others
|
|
1-Stearoyl-sn-glycerol 3-phosphate sodium is a bioactive phospholipid that plays a crucial role in modulating cellular processes such as motility, proliferation, invasion, survival, and growth factor production, primarily through its interaction with G protein-coupled receptors (GPCRs). Typically found at low concentrations in plasma (~100nM), this compound is synthesized during the formation of membrane phospholipids and is derived from various cell types, including activated platelets, epithelial cells, leukocytes, neuronal cells, and tumor cells. Its unique structure includes stearic acid at the sn-1 position alongside a hydroxyl group at the sn-2 position.
|
-
- HY-W923483
-
|
1-O-Hexadecyl-2-oleoyl-SN-glycero-3-phosphocholine
|
Platelet-activating Factor Receptor (PAFR)
Endogenous Metabolite
|
Cardiovascular Disease
|
|
C16-18:1 PC (1-O-Hexadecyl-2-oleoyl-sn-glycero-3-phosphocholine), also known as 1-O-hexadecyl-2-oleoyl-sn-glycero-3-phosphocholine (HOPC), is a member of the platelet-activating factor (PAF) family of glycerophospholipids and serves as a pro-inflammatory lipid mediator with diverse biological and pharmacological effects; it features a mono-ether structure with an oleoyl chain (18:1) ester-linked at the sn-2 position and a hexadecyl chain (16:0) ether-linked at the sn-1 position.
|
-
- HY-126726
-
|
|
Biochemical Assay Reagents
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Others
|
|
Oxidized low-density lipoprotein (oxLDL) particles contain low molecular weight species that are cytotoxic and proatherogenic. Many of these species were recently isolated and purified from oxLDL and identified as phosphatidylcholine species containing fragmented oxidized short-chain fatty acid residues at the sn-2 position. 1-(Palmitoyl)-2-(5-keto-6-octene-dioyl)phosphatidylcholine or KOdiA-PC is one of the most potent CD36 ligands of the oxLDL species. KOdiA-PC confers CD36 scavenger receptor binding affinity to LDL at a frequency of only 2 to 3 KOdiA-PC molecules/LDL particle and may be one of the more important structural determinants of oxLDL.
|
-
- HY-157693
-
|
|
Endogenous Metabolite
|
Cancer
|
|
C18:1 Cyclic LPA is a naturally occurring analog of the growth factor-like phospholipid mediator, lysophosphatidic acid (LPA), characterized by the formation of a 5-membered ring between its sn-2 hydroxy group and the sn-3 phosphate. This unique structure allows C18:1 Cyclic LPA to influence a variety of cellular functions, such as inhibiting cell cycle progression, promoting the formation of stress fibers, curtailing tumor cell invasiveness and metastasis, and modulating the differentiation and survival of neuronal cells. Notably, many of these cellular effects elicited by C18:1 Cyclic LPA appear to counter those induced by LPA, despite the activation of seemingly similar receptor populations.
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-
- HY-145540
-
|
1,2-Palmitin-3-caprylin
|
Biochemical Assay Reagents
|
Metabolic Disease
|
|
1,2-Dipalmitoyl-3-Octanoyl-rac-glycerol is a triacylglycerol containing palmitic acid (HY-N0830) at the sn-1 and sn-2 positions and octanoic acid (HY-41417) at the sn-3 position. Palmitic acid is a long-chain saturated fatty acid commonly found in both animals and plants. PA can induce the expression of glucose-regulated protein 78 (GRP78) and CCAAT/enhancer binding protein homologous protein (CHOP) in in mouse granulosa cells. Octanoic acid is an oily liquid with a slightly unpleasant rancid taste and used commercially in the production of esters used in perfumery and also in the manufacture of dyes. Octanoic acid is also a tremor-suppressing agent [2] .
|
-
- HY-168371
-
|
|
Scavenger Receptor Class B type I (SR-BI）
|
Metabolic Disease
|
|
1-Palmitoyl-2-13(S)-HODE-sn-glycero-3-PC (13-HODE-PC) is an oxidized phospholipid that contains Palmitic acid (HY-N0830) and 13(S)-HODE (HY-113884B) at the sn-1 and sn-2 positions, respectively. 1-Palmitoyl-2-13(S)-HODE-sn-glycero-3-PC has the ability to compete for the binding of 125I-NO2-LDL (5 g/mL) to CD36-transfected 293 cells, with the IC50 of ＞ 200 μM .
|
-
- HY-145473
-
|
15(S)-HETE-SAPE; 15(S)-Hydroxyeicosatetraenoic acid-SAPE; 1-Stearoyl-2-15(S)-HETE-SN-glycero-3-Phosphatidylethanolamine
|
Endogenous Metabolite
|
Metabolic Disease
|
|
1-Stearoyl-2-15(S)-HETE-sn-glycero-3-PE (15(S)-HETE-SAPE) is a phospholipid containing stearic acid (HY-B2219) at the sn-1 position and 15(S)-HETE (HY-113336) at the sn-2 position. 1-Stearoyl-2-15(S)-HETE-sn-glycero-3-PE is formed by direct oxidation of 1-stearoyl-2-arachidonoyl-sn-glycero-3-PE (SAPE) by 15-LOX in human peripheral mononuclear cells activated with the calcium ionophore A23187 (HY-N6687).
|
-
- HY-145504
-
|
1,2-Palmitin-3-Linoelaidin
|
Biochemical Assay Reagents
|
Metabolic Disease
|
|
12-Dipalmitoyl-3-Linoelaidoyl-rac-glycerol is a triacylglycerol containing palmitic acid (HY-N0830) at the sn-1 and sn-2 positions and linoelaidic acid (HY-W071746) at the sn-3 position. Palmitic acid is a long-chain saturated fatty acid commonly found in both animals and plants. Palmitic acid can induce the expression of glucose-regulated protein 78 (GRP78) and CCAAT/enhancer binding protein homologous protein (CHOP) in in mouse granulosa cells. Linolelaidic acid, an omega-6 trans fatty acid, acts as a source of energy. Linolelaidic acid is an essential nutrient, adding in enteral, parenteral, and infant formulas. Linolelaidic acid can be used for heart diseases research [2] .
|
-
- HY-W127357
-
|
|
Biochemical Assay Reagents
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Others
|
|
Glyceryl trinonanoate is a triacylglycerol containing nonanoic acid at the sn-1, sn-2 and sn-3 positions. It has been found in Schizochytrium biomass. 1 1,2,3-Trinonanoyl-rac-glycerol increases blood levels of the ketone body D-(-)-3-hydroxybutyrate in neonatal rhesus monkeys. 2|1. Mioso, R., Toledo Marante, FJ, González, JE, et al. Schizochytrium sp. metabolite analysis. Oleaginous microbial sources of biodiesel by GC-MS. braz. J. Microbiology. 45(2), 403-409 (2014).|2. Tetrick, MA, Greer, FR and Benevenga, NJ Blood D- ( )-3-Hydroxybutyric acid concentration. Compare. medicine. 60(6), 486-490 (2010).
|
-
- HY-156041
-
|
Lyso-PE (egg); LPE (egg); L-α-lysophosphatidylethanolamine
|
Endogenous Metabolite
|
Metabolic Disease
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Lysophosphatidylethanolamine (LPE) is a naturally-occurring lysophospholipid that can be generated via deacylation of phosphatidylethanolamine by phospholipase A2 (PLA2). It increases the phosphorylation of ERK1/2 in PC12 cells, an effect that can be blocked by the MEK inhibitors U-0126 (HY-12031A) and PD 98059 (HY-12028) and the EGFR inhibitor AG-1478 (HY-13524).1 LPE also increases neurite outgrowth and expression of neurofilament M in PC12 cells. LPE inhibits the activity of phospholipase D (PLD) partially purified from cabbage.3 This product contains lysophosphatidylethanolamine molecular species with variable fatty acyl chain lengths at the sn-1 position and a hydroxy group at the sn-2 position.
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- HY-115701
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1-Stearoyl-2-15(S)-HpETE-SN-glycero-3-phosphoethanolamine; 15(S)-HpETE-SAPE; 15(S)-hydroperoxyeicostetraenoic acid-SAPE
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Ferroptosis
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Inflammation/Immunology
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1-Stearoyl-2-15(S)-HpETE-sn-glycero-3-Pe is a phospholipid that contains stearic acid (HY-B2219) at the sn-1 position and 15(S)-HpETE at the sn-2 position. It is produced via oxidation of 1-stearoyl-2-arachidonoyl-sn-glycero-3-Pe (SAPE) by 15-lipoxygenase (15-LO). 1-Stearoyl-2-15(S)-HpETE-sn-glycero-3-Pe (0.6 and 0.9 μM) increases ferroptotic cell death in wild-type and Acsl4 knockout Pfa1 mouse embryonic fibroblasts (MEFs) treated with the GPX4 inhibitor RSL3.
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- HY-141636S
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1-Palmitoyl-2-arachidonoyl-SN-glycero-3-phosphocholine-d9-1; PAPC-d9-1; PC(16:0/20:4)-d9-1
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Isotope-Labeled Compounds
Endogenous Metabolite
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Cardiovascular Disease
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1-PalMitoyl-2-arachidoyllecithin-d9-1 (1-Palmitoyl-2-arachidonoyl-sn-glycero-3-phosphocholine-d9-1) is deuterium labeled 1-PalMitoyl-2-arachidoyllecithin. 1-Palmitoyl-2-arachidonoyl-sn-glycero-3-PC (PAPC) is a phospholipid containing palmitic acid (16:0) and arachidonic acid (20:4) at the sn-1 and sn-2 positions, respectively, that is found in biological membranes. PAPC is oxidized in vivo, and its oxidation products are involved in chronic inflammation and vascular disease. PAPC has been used to study signaling of oxidized phospholipids. Levels of PAPC are decreased in isolated human multiple myeloma cells .
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- HY-112747
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LPI; PE (soy)
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Phospholipase
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Infection
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Soy PE (LPI) is the most abundant phospholipid in prokaryotes and the second most abundant found in the membrane of mammalian, plant, and yeast cells, comprising approximately 25% of total mammalian phospholipids. In the brain, phosphatidylethanolamine comprises almost half of the total phospholipids. It is synthesized mainly through the cytidine diphosphate-ethanolamine and phosphatidylserine decarboxylation pathways, which occur in the endoplasmic reticulum (ER) and mitochondrial membranes, respectively. It is a precursor in the synthesis of phosphatidylcholine and arachidonoyl ethanolamide and is a source of ethanolamine used in various cellular functions. In E.coli, phosphatidylethanolamine deficiency prevents proper assembly of lactose permease, suggesting a role as a lipid chaperone. It is a cofactor in the propagation of prions in vitro and can convert recombinant mammalian proteins into infectious molecules even in the absence of RNA. This product contains phosphatidylethanolamine molecular species with variable fatty acyl chain lengths at the sn-1 and sn-2 positions .
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- HY-W127391
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(Rac)-1,2-Didodecanoylglycerol
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Biochemical Assay Reagents
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Others
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1,2-Dilaurin is a diacylglycerol containing lauric acid at the sn-1 and sn-2 positions. It has been used as an internal standard for the quantification of diglycerides in rat desheathed sciatic nerves. [1] Monomolecular films containing 1,2-dilauroyl-rac-glycerol have been used as substrates to measure surface pressure and the effect of pancreatic procolipase and colipase on porcine pancreatic lipase activity. [2] References: [1]. Zhu, X. and Eichberg, J. 1,2-Diacylglycerol content and its arachidonyl-containing molecular species are reduced in the sciatic nerve of streptozotocin-induced diabetic rats. J. Neurochemistry. 55(3), 1087-1090 (1990).[2]. Wieloch, T., Borgstr m, B., Piéroni, G. et al. Porcine trypsinogen and its trypsin-activated form: lipid binding and lipase activation on monomolecular membranes. FEBS Express. 128(2), 217-220 (1981).
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- HY-RS13223
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Small Interfering RNA (siRNA)
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Others
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SLC38A5 Human Pre-designed siRNA Set A contains three designed siRNAs for SLC38A5 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
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SLC38A5 Human Pre-designed siRNA Set A
SLC38A5 Human Pre-designed siRNA Set A
- HY-W010736A
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Biochemical Assay Reagents
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Others
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1,2-Dipalmitoyl-rac-glycerol is a diacylglycerol containing palmitic acid at the sn-1 and sn-2 positions (Cat. No. 10006627). It is found in a variety of vegetable oils, including palm, soybean, canola, and corn. 1 \n 1,2-Dipalmitoyl-rac-glycerol MaxSpec Standard is a quantitative grade standard of 1,2-dipalmitoyl-rac-glycerol prepared for mass spectrometry and related applications requiring quantitative reproducibility . The solution has been prepared gravimetrically and contained in argon-sealed deactivated glass ampoules. Concentrations were verified by comparison to independently prepared calibration standards. This 1,2-dipalmitoyl-rac-glycerol MaxSpec Standard is guaranteed to meet specifications for identity, purity, stability, and concentration and is supplied with a batch-specific Certificate of Analysis. Ongoing stability testing is performed to ensure concentrations remain accurate throughout the shelf life of the product. Note: Add more solution to the vial than listed. Therefore, accurate volume measurements are necessary to prepare calibration standards. Follow recommended storage and handling conditions to maintain product quality.
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- HY-145473S
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15(S)-HETE-SAPE; 15(S)-Hydroxyeicosatetraenoic acid-SAPE-d11; 1-Stearoyl-2-15(S)-HETE-SN-glycero-3-Phosphatidylethanolamine-d11
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Isotope-Labeled Compounds
Others
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Metabolic Disease
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1-Stearoyl-2-15(S)-HETE-sn-glycero-3-PE-d11 (15(S)-HETE-SAPE-d11) is deuterium labeled 1-Stearoyl-2-15(S)-HETE-sn-glycero-3-PE. 1-Stearoyl-2-15(S)-HETE-sn-glycero-3-PE is a phospholipid that contains stearic acid (HY-B2219) at the sn-1 position and 15(S)-HETE at the sn-2 position. It is formed in human peripheral monocytes activated by the calcium ionophore A23187 (HY-N6687) by direct oxidation of 1-stearoyl-2-arachidonoyl-sn-glycero-3-PE (SAPE) by 15-LO. Phosphoethanolamine (PE) HETEs (PE-HETEs), including 1-stearoyl-2-15(S)-HETE-sn-glycero-3-PE, are the main source of esterified HETE in ionophore-activated monocytes .
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- HY-141631
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L-α-Phosphatidylcholine
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Biochemical Assay Reagents
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Others
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Dihomo-γ-Linolenoyl PAF C-16is a PAFanalogue, it is in sn-2location contains dihomo-γ-linolenoate, instead of PAF C-16The acetate part in .
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- HY-W096441
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Pramipexole impurity E
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Drug Intermediate
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Others
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(S)-N-(2-Amino-4,5,6,7-tetrahydrobenzo[d]thiazol-6-yl)propionamide (Pramipexole propionamide) is a drug impurity.
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| Cat. No. |
Product Name |
Type |
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- HY-W713925
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Fluorescent Dye
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Diheptanoyl Thio-PC is a substrate for all phospholipase A2s (PLA2s) with the exception of cPLA2 and PAF-acetyl hydrolase (PAF-AH).1 Interaction of this compound with a PLA2 results in cleavage of the sn-2 fatty acid generating a free thiol on the lysophospholipid. This free thiol can be detected using chromogenic substrates such as DTNB (Ellman’s reagent) and DTP.
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| Cat. No. |
Product Name |
Type |
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- HY-141571
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Dioleoylphosphatidylglycerol sodium
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Biochemical Assay Reagents
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DOPG sodium is a naturally occurring anionic phospholipid, containing oleic acid (18:1) inserted at the sn-1 and sn-2 positions. DOPG can form a lipid bilayer in an aqueous solution and is used in the generation of micelles, liposomes, and other artificial membranes. DOPG also exhibits anti-inflammatory properties .
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- HY-125940
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1,2-Dipalmitoyl-SN-glycero-3-phosphoglycerol sodium
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Biochemical Assay Reagents
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DPPG (1,2-Dipalmitoyl-sn-glycero-3-phosphoglycerol sodium) is a phospholipid that contains long-chain (16:0) palmitic acid inserted at the sn-1 and sn-2 positions, and it serves as an active component to prevent BaP molecules from entering the water subphase. DPPG is used to prepare micelles, liposomes, and other types of artificial membranes that can resist damage from UV radiation [2] .
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- HY-19997
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TATM
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Biochemical Assay Reagents
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Mannose triflate is a glucose analog. Mannose triflate is a precursor for 18F-FDG synthesis for PET applications. Mannose triflate binds to 18F via SN2 nucleophilic substitution reaction. Mannose triflate can be used for an imaging technique in detection of cancer [2] .
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- HY-126726
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Biochemical Assay Reagents
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Oxidized low-density lipoprotein (oxLDL) particles contain low molecular weight species that are cytotoxic and proatherogenic. Many of these species were recently isolated and purified from oxLDL and identified as phosphatidylcholine species containing fragmented oxidized short-chain fatty acid residues at the sn-2 position. 1-(Palmitoyl)-2-(5-keto-6-octene-dioyl)phosphatidylcholine or KOdiA-PC is one of the most potent CD36 ligands of the oxLDL species. KOdiA-PC confers CD36 scavenger receptor binding affinity to LDL at a frequency of only 2 to 3 KOdiA-PC molecules/LDL particle and may be one of the more important structural determinants of oxLDL.
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- HY-W127380
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Biochemical Assay Reagents
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Arachidonoyl Thio-PC is a substrate of many phospholipase A2 (PLA2), including sPLA2, cPLA2 and iPLA2. Cleavage of sn-2 fatty acids by PLA2 results in the production of free thiols, which react with chromogenic reagents such as DTNB (Ellman's reagent) and DTP, allowing quantification of PLA2 activity. Isozyme-specific cPLA2 activity can be measured by depleting or inhibiting sPLA2 and iPLA2 activity in the assay.
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-
- HY-W127391
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(Rac)-1,2-Didodecanoylglycerol
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Biochemical Assay Reagents
|
|
1,2-Dilaurin is a diacylglycerol containing lauric acid at the sn-1 and sn-2 positions. It has been used as an internal standard for the quantification of diglycerides in rat desheathed sciatic nerves. [1] Monomolecular films containing 1,2-dilauroyl-rac-glycerol have been used as substrates to measure surface pressure and the effect of pancreatic procolipase and colipase on porcine pancreatic lipase activity. [2] References: [1]. Zhu, X. and Eichberg, J. 1,2-Diacylglycerol content and its arachidonyl-containing molecular species are reduced in the sciatic nerve of streptozotocin-induced diabetic rats. J. Neurochemistry. 55(3), 1087-1090 (1990).[2]. Wieloch, T., Borgstr m, B., Piéroni, G. et al. Porcine trypsinogen and its trypsin-activated form: lipid binding and lipase activation on monomolecular membranes. FEBS Express. 128(2), 217-220 (1981).
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- HY-W127357
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Biochemical Assay Reagents
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Glyceryl trinonanoate is a triacylglycerol containing nonanoic acid at the sn-1, sn-2 and sn-3 positions. It has been found in Schizochytrium biomass. 1 1,2,3-Trinonanoyl-rac-glycerol increases blood levels of the ketone body D-(-)-3-hydroxybutyrate in neonatal rhesus monkeys. 2|1. Mioso, R., Toledo Marante, FJ, González, JE, et al. Schizochytrium sp. metabolite analysis. Oleaginous microbial sources of biodiesel by GC-MS. braz. J. Microbiology. 45(2), 403-409 (2014).|2. Tetrick, MA, Greer, FR and Benevenga, NJ Blood D- ( )-3-Hydroxybutyric acid concentration. Compare. medicine. 60(6), 486-490 (2010).
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- HY-141631
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L-α-Phosphatidylcholine
|
Biochemical Assay Reagents
|
|
Dihomo-γ-Linolenoyl PAF C-16is a PAFanalogue, it is in sn-2location contains dihomo-γ-linolenoate, instead of PAF C-16The acetate part in .
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-
- HY-W127408
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Biochemical Assay Reagents
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1,2,3-Tripalmitoleoyl-rac-glycerol is a triacylglycerol containing palmitoleic acid at the sn-1, sn-2 and sn-3 positions. It reduces erythrocyte deformability in a concentration-dependent manner in the Reid filtration assay. Hepatic levels of 1,2,3-tripalmitoleoyl-rac-glycerol are increased in a JAK2L mouse model of hepatic steatosis. 1,2,3-Tripalmitoleoyl-rac-glycerol plasma levels are reduced in patients with predialysis renal disease.
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- HY-157683
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Biochemical Assay Reagents
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16:0-18:1 Diether PG is a type of glycerophospholipids, in which the hexadecane and octadecene chains are connected to the sn-1 and sn-2 positions of the glycerol backbone via ether bonds, respectively. 16:0-18:1 Diether PG can be used to prepare liposomes .
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- HY-W010736A
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Biochemical Assay Reagents
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1,2-Dipalmitoyl-rac-glycerol is a diacylglycerol containing palmitic acid at the sn-1 and sn-2 positions (Cat. No. 10006627). It is found in a variety of vegetable oils, including palm, soybean, canola, and corn. 1 \n 1,2-Dipalmitoyl-rac-glycerol MaxSpec Standard is a quantitative grade standard of 1,2-dipalmitoyl-rac-glycerol prepared for mass spectrometry and related applications requiring quantitative reproducibility . The solution has been prepared gravimetrically and contained in argon-sealed deactivated glass ampoules. Concentrations were verified by comparison to independently prepared calibration standards. This 1,2-dipalmitoyl-rac-glycerol MaxSpec Standard is guaranteed to meet specifications for identity, purity, stability, and concentration and is supplied with a batch-specific Certificate of Analysis. Ongoing stability testing is performed to ensure concentrations remain accurate throughout the shelf life of the product. Note: Add more solution to the vial than listed. Therefore, accurate volume measurements are necessary to prepare calibration standards. Follow recommended storage and handling conditions to maintain product quality.
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- HY-170466
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1-Palmitoyl-2-stearoyl-(12-doxyl)-SN-glycero-3-phosphocholine
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Biochemical Assay Reagents
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|
16:0-12 Doxyl PC (1-Palmitoyl-2-stearoyl-(12-doxyl)-sn-glycero-3-phosphocholine) is a fluorescence quencher, and its nitrogen oxide is located downstream of the sn-2 chain. 16:0-12 Doxyl PC has a better fluorescence quenching effect onthe fluorophore is buried within the hydrocarbon interior of the bilayer .
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| Cat. No. |
Product Name |
Target |
Research Area |
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- HY-P10053
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Phospholipase
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Metabolic Disease
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sPLA2-IIA Inhibitor is a cyclic pentapeptide analog of FLSYK (cyclic 2-Nal-Leu-Ser-2-Nal-Arg (c2)), that binds to hGIIA (human IIA phospholipase A2) and inhibits its hydrolytic ability. sPLA2 is a member of the esterase superfamily that catalyzes the hydrolysis of the ester bond at the sn-2 position of glycerophospholipids, releasing free fatty acids such as arachidonic acid and lysophospholipids .
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| Cat. No. |
Product Name |
Category |
Target |
Chemical Structure |
-
- HY-W019833
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-
-
- HY-W440982A
-
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(Rac)-PC(18:0/18:1); (Rac)-2-Oleoyl-1-stearoyl-SN-glycero-3-phosphocholine
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Structural Classification
Animals
Lipid
Source Classification
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Liposome
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|
(Rac)-SOPC ((Rac)-PC(18:0/18:1)) ((Rac)-2-Oleoyl-1-stearoyl-sn-glycero-3-phosphocholine) is the racemate of SOPC (HY-W440982). SOPC is an asymmetrical phospholipid with saturated fatty acid (stearic acid/18:0) at sn-1 position and unsaturated fatty acid (oleic acid/18:1) at sn-2 position. SOPC can stabilize the outer segment membrane of frog rods .
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-
- HY-N7859
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-
| Cat. No. |
Product Name |
Chemical Structure |
-
- HY-125940S
-
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DPPG-d62 (sodium) is deuterium labeled DPPG. DPPG sodium (1,2-Dipalmitoyl-sn-glycero-3-PG sodium) is a phospholipid containing the long-chain(16:0) palmitic acid inserted at the sn-1 and sn-2 positions. DPPG sodium is used in the generation of micelles, l
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-
-
- HY-141636S
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1-PalMitoyl-2-arachidoyllecithin-d9-1 (1-Palmitoyl-2-arachidonoyl-sn-glycero-3-phosphocholine-d9-1) is deuterium labeled 1-PalMitoyl-2-arachidoyllecithin. 1-Palmitoyl-2-arachidonoyl-sn-glycero-3-PC (PAPC) is a phospholipid containing palmitic acid (16:0) and arachidonic acid (20:4) at the sn-1 and sn-2 positions, respectively, that is found in biological membranes. PAPC is oxidized in vivo, and its oxidation products are involved in chronic inflammation and vascular disease. PAPC has been used to study signaling of oxidized phospholipids. Levels of PAPC are decreased in isolated human multiple myeloma cells .
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-
- HY-W710512
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Propane-1,2,3-triyl tritricosanoate-d5 (Glycerol Tritricosanoate-d5) is deuterium labeled Propane-1,2,3-triyl tritricosanoate. 1,2,3-Tritricosanoyl glycerol is a triacylglycerol that contains tricosanoic acid (HY-W009081) at the sn-1, sn-2, and sn-3 positions. It has been used as an internal standard for the quantification of fatty acids in the triglyceride component of human aortic endothelial cells (HAECs) grown in media supplemented with stearic and/or oleic acid.
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-
- HY-145473S
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1-Stearoyl-2-15(S)-HETE-sn-glycero-3-PE-d11 (15(S)-HETE-SAPE-d11) is deuterium labeled 1-Stearoyl-2-15(S)-HETE-sn-glycero-3-PE. 1-Stearoyl-2-15(S)-HETE-sn-glycero-3-PE is a phospholipid that contains stearic acid (HY-B2219) at the sn-1 position and 15(S)-HETE at the sn-2 position. It is formed in human peripheral monocytes activated by the calcium ionophore A23187 (HY-N6687) by direct oxidation of 1-stearoyl-2-arachidonoyl-sn-glycero-3-PE (SAPE) by 15-LO. Phosphoethanolamine (PE) HETEs (PE-HETEs), including 1-stearoyl-2-15(S)-HETE-sn-glycero-3-PE, are the main source of esterified HETE in ionophore-activated monocytes .
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| Cat. No. |
Product Name |
|
Classification |
-
- HY-141571
-
|
Dioleoylphosphatidylglycerol sodium
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|
Phospholipids
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|
DOPG sodium is a naturally occurring anionic phospholipid, containing oleic acid (18:1) inserted at the sn-1 and sn-2 positions. DOPG can form a lipid bilayer in an aqueous solution and is used in the generation of micelles, liposomes, and other artificial membranes. DOPG also exhibits anti-inflammatory properties .
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-
- HY-125940
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1,2-Dipalmitoyl-SN-glycero-3-phosphoglycerol sodium
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|
Phospholipids
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DPPG (1,2-Dipalmitoyl-sn-glycero-3-phosphoglycerol sodium) is a phospholipid that contains long-chain (16:0) palmitic acid inserted at the sn-1 and sn-2 positions, and it serves as an active component to prevent BaP molecules from entering the water subphase. DPPG is used to prepare micelles, liposomes, and other types of artificial membranes that can resist damage from UV radiation [2] .
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- HY-W019833
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PC(14:0/18:0); 1-Myristoyl-2-stearoyl-SN-glycero-3-phosphocholine
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Phospholipids
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MSPC is an asymmetrical phosphatidylcholine containing a myristic acid (14:0) at the sn-1 position and a stearic acid (18:0) at the sn-2 position. It can self assemble in water to form lipid bilayers. Reagent grade, for research purpose.
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- HY-157693
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Phospholipids
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C18:1 Cyclic LPA is a naturally occurring analog of the growth factor-like phospholipid mediator, lysophosphatidic acid (LPA), characterized by the formation of a 5-membered ring between its sn-2 hydroxy group and the sn-3 phosphate. This unique structure allows C18:1 Cyclic LPA to influence a variety of cellular functions, such as inhibiting cell cycle progression, promoting the formation of stress fibers, curtailing tumor cell invasiveness and metastasis, and modulating the differentiation and survival of neuronal cells. Notably, many of these cellular effects elicited by C18:1 Cyclic LPA appear to counter those induced by LPA, despite the activation of seemingly similar receptor populations.
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- HY-W040185
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1,2-DPPA sodium; PA(14:0/14:0) sodium; 1,2-Dimyristoyl-SN-glycero-3-phosphate sodium
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Phospholipids
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1,2-Dimyristoyl-sn-glycero-3-phosphate monosodium is a phospholipid containing the long-chain (14:0) myristic acid inserted at the sn-1 and sn-2 positions. It can be used in the generation of micelles, liposomes, and other types of artificial membranes.
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-
- HY-157697
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18:0p/20:4-PE; C18(Plasm)-20:4-PE; PE(P-18:0/20:4)
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Phospholipids
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1-1(Z)-Octadecenyl-2-arachidonoyl-sn-glycero-3-PE (18:0p/20:4-PE; C18(Plasm)-20:4-PE) is a plasmalogen that contains 1(Z)-octadecenoic acid and arachidonic acid (HY-109590) at the sn-1 and sn-2 positions, respectively.
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-
- HY-141636
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1-Palmitoyl-2-arachidonoyl-SN-glycero-3-phosphocholine; PAPC; PC(16:0/20:4)
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Phospholipids
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1-Palmitoyl-2-arachidonoyl-sn-glycero-3-PC (PAPC) is a phospholipid containing palmitic acid (16:0) and arachidonic acid (20:4) at the sn-1 and sn-2 positions, respectively, that is found in biological membranes. PAPC is oxidized in vivo, and its oxidation products are involved in chronic inflammation and vascular disease. PAPC has been used to study signaling of oxidized phospholipids. Levels of PAPC are decreased in isolated human multiple myeloma cells.
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-
- HY-W440981
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1-Stearoyl-2-palmitoyl-SN-glycero-3-phosphocholine
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|
Phospholipids
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SPPC is a phospholipid with different length of fatty acid. The sn-1 position contains a stearic acid (18:0) while the sn-2 position is occupied by a palmitic acid (16:0).
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- HY-W704966
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Phospholipids
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2-Stearoyl-sn-glycero-3-PC is a lysophospholipid that contains stearic acid (HY-B2219) at the sn-2 position. It has been found in rabbit myocardium.
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-
- HY-W440983
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|
PC(18:0/22:6); DHA-PC; 1-Stearoyl-2-docosahexaenoyl-SN-glyerco-3-phosphocholine
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Phospholipids
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SDPC (DHA-PC) is a new generation of omega-3 lipids, which contains an ester bond linking DHA at the sn-2 position of phospholipid. 1-Stearoyl-2-docosahexaenoyl-sn-glyerco-3-phosphocholine exerts anti-angiogenesis effect through activating PPARγ. 1-Stearoyl-2-docosahexaenoyl-sn-glyerco-3-phosphocholine significantly declines the proliferation, migration, tube formation of human umbilical vein endothelial cells. 1-Stearoyl-2-docosahexaenoyl-sn-glyerco-3-phosphocholine has the potential for anti-tumor angiogenesis research .
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-
- HY-W583869
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1-Stearoyl-2-Oleoyl-SN-glycero-3-PE; 18:0-18:1 PE; PE(18:0/18:1)
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|
Phospholipids
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|
1-Stearoyl-2-oleoyl-sn-glycerol-3-phosphoethanolamine is a phospholipids that contains stearic acid and oleic acid at the sn-1 and sn-2 positions, respectively. It has been used in the generation of lipid nanoparticles (LNPs) for in vitro delivery of mRNA or nuclear-targeted plasmid DNA.
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-
- HY-131652
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16:0 Diether PC
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|
Phospholipids
|
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1,2-Di-O-hexadecyl-sn-glycero-3-phosphocholine (16:0 Diether PC) is a synthetic ether-linked phospholipid containing hexadecyl groups at the sn-1 and sn-2 positions. It is commonly used in the generation of liposomes and artificial membranes to study membrane dynamics.
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-
- HY-157698
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C18(plasm)-20:4-PC; 18:0p/20:4-PC; PC(P-18:0/20:4)
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Phospholipids
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1-1(Z)-Octadecenyl-2-arachidonoyl-sn-glycero-3-PC is a plasmalogen that contains 1(Z)-octadecenoic acid and arachidonic acid (HY-109590) at the sn-1 and sn-2 positions, respectively. It scavenges singlet oxygen in a cell-free assay.
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-
- HY-W440958
-
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PSPC; PC(16:0-18:0)
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|
Phospholipids
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1-Palmitoyl-2-stearoyl-sn-glycero-3-phosphocholine is an assymetrical phospholipid containing saturated palmitic and stearic acid at the sn-1 and sn-2 position respectively. The phosphate group is attached to choline.
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-
- HY-141614
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Phosphatidylcholine Diarachidoyl; 1,2-DAPC; L-α-Diarachidonoyl lecithin
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Phospholipids
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1,2-Diarachidoyl-sn-glycero-3-phosphocholine (1,2-DAPC) is a phospholipid containing the saturated long-chain (20:0) arachidic acid inserted at the sn-1 and sn-2 positions. It can be used in the generation of micelles, liposomes, and other types of artificial membranes.
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- HY-W343736
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1,3-DPPE; 1,3-Dipalmitoyl-SN-glycero-2-PE
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Phospholipids
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1,3-Dipalmitoyl-glycero-2-phosphoethanolamine is a phospholipid containing the saturated long-chain (16:0) stearic acid inserted at the sn-1 and sn-3 positions and PE at the sn-2 site. It can be used in the generation of micelles, liposomes, and other types of artificial membranes.
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- HY-W440982A
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(Rac)-PC(18:0/18:1); (Rac)-2-Oleoyl-1-stearoyl-SN-glycero-3-phosphocholine
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Phospholipids
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(Rac)-SOPC ((Rac)-PC(18:0/18:1)) ((Rac)-2-Oleoyl-1-stearoyl-sn-glycero-3-phosphocholine) is the racemate of SOPC (HY-W440982). SOPC is an asymmetrical phospholipid with saturated fatty acid (stearic acid/18:0) at sn-1 position and unsaturated fatty acid (oleic acid/18:1) at sn-2 position. SOPC can stabilize the outer segment membrane of frog rods .
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- HY-W440957
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PC(16:0/14:0); 1-palmitoyl-2-myristoyl-SN-glycero-3-phosphocholine
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Phospholipids
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PMPC is a phosphatidylcholine with asymmetrical fatty acid. Palmitic acid occupies sn-1 position while myristic acid is placed at the sn-2 position.
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- HY-W800733
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1,2-Dilauroyl-SN-glycero-3-phosphorylglycerol; PG(12:0/12:0)
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Phospholipids
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DLPG is a phospholipid containing lauric acid (12 chain fatty acid) inserted at the sn-1 and sn-2 positions. Its phosphate group is attached to glycerol. It is used in the generation of micelles, liposomes, and other artificial membranes.
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- HY-W590536
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1-Palmitoyl-2-Lauroyl-SN-glycero-3-Phosphatidylcholine; 1-Palmitoyl-2-Lauroyl-SN-glycero-3-Phosphocholine
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Phospholipids
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1,2-PLPC is a phospholipid containing palmitoyl (16:0) and lauryl (12:0) acyl substituents at the sn-1 and sn-2 positions, respectively. It can be used in the generation of micelles, liposomes, and other types of artificial membranes.
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- HY-113925
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1,2-DLPA Sodium; (2R)-2,3-bis(dodecanoyloxy)propyl hydrogen phosphate sodium
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Phospholipids
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1,2-Dilauroyl-sn-glycero-3-phosphate (1,2-DLPA) sodium is a phospholipid containing the medium-chain (12:0) lauric acid inserted at the sn-1 and sn-2 positions. It can be used in the generation of micelles, liposomes, and other types of artificial membranes.
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- HY-W725327
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1,2-Dipropionyl-SN-glycero-3-Phosphatidylcholine; 1,2-Dipropionyl-SN-glycero-3-Phosphocholine; PC(3:0/3:0)
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Phospholipids
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1,2-Dipropionyl-sn-glycero-3-PC is a phospholipid containing propionic acid at the sn-1 and sn-2 positions. It has been used to study the interaction between water and the phosphocholine headgroup in aqueous solutions.
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- HY-157683
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Phospholipids
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16:0-18:1 Diether PG is a type of glycerophospholipids, in which the hexadecane and octadecene chains are connected to the sn-1 and sn-2 positions of the glycerol backbone via ether bonds, respectively. 16:0-18:1 Diether PG can be used to prepare liposomes .
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- HY-134174
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Phospholipids
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1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphate is a phospholipid containing saturated palmitic acid (16:0) and monounsaturated oleic acid (18:1) inserted at the sn-1 and sn-2 positions, respectively. It can be used in the generation of micelles, liposomes, and other types of artificial membranes.
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- HY-W800734
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MPPC; PC(14:0/16:0)
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Phospholipids
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1-Myristoyl-2-palmitoyl-sn-glycero-3-phosphocholine (MPPC) is an asymmetrical phosphatidylcholine containing a myristic acid (14:0) at the sn-1 position and a palmitic acid (16:0) at the sn-2 position. It is commonly used in the generation of micelles, liposomes, and other types of artificial membranes.
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- HY-175069
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PA(18:1/18:1) ammonium salt; 1,2-DOPA ammonium salt
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Phospholipids
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1,2-Dioleoyl-sn-glycero-3-PA (ammonium salt) is a phospholipid with long-chain fatty acid oleic acid inserted at the sn-1 and sn-2 positions. 1,2-Dioleoyl-sn-glycero-3-PA (ammonium salt) can be used to synthsize artificial membranes such as liposomes [2].
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- HY-145545
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PE(18:0/22:4); 1-Stearoyl-2-Docosatraenoyl-SN-glycero-3-PE
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Phospholipids
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1-Stearoyl-2-adrenoyl-sn-glycero-3-PE is a phospholipid that contains stearic acid (HY-B2219) and adrenic acid (HY-W013215) at the sn-1 and sn-2 positions, respectively. 1-Stearoyl-2-adrenoyl-sn-glycero-3-PE levels are inversely correlated with subject age in mitochondria isolated from human post-mortem hippocampus.
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- HY-RS13223
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siRNAs
Human Pre-designed siRNA Sets
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SLC38A5 Human Pre-designed siRNA Set A contains three designed siRNAs for SLC38A5 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
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- HY-175111
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Phospholipids
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1-Stearoyl-2-17(S)-HDoTE-sn-glycero-3-PC is a phospholipid that contains stearic acid (HY-B2219) and the oxidized adrenic acid metabolite 17(S)-HDoTE (HY-168774) at the sn-1 and sn-2 positions, respectively .
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- HY-175115
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Phospholipids
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1-Stearoyl-2-17(S)-HDoTE-sn-glycero-3-PE is a phospholipid. 1-Stearoyl-2-17(S)-HDoTE-sn-glycero-3-PE contains Stearic acid (HY-B2219) and the oxidized adrenic acid metabolite 17(S)-HDoTE (HY-168774) at the sn-1 and sn-2 positions, respectively.
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