3 Results for "

Salvianolic acid D

" in MedChemExpress (MCE) Product Catalog:
Products (3)

3 Results for "Salvianolic acid D" in MCE Product Catalog:

Salvianolic acid D
Salvianolic acid D
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Cat. No.: HY-N0320
CAS No.: 142998-47-8
Category:  

Cardiovascular Disease Labiatae Samanea saman (Jacq.) Merr. Lignans Phenols Polyphenols Phenylpropanoids Plants Disease Research Fields

Target:  

Bcl-2 Family Caspase Toll-like Receptor (TLR) MyD88 NF-κB

Salvianolic acid D is a depside. Salvianolic acid D can be isolated from Salvia miltiorrhiza (Danshen). Salvianolic acid D promotes the expression of Bcl-2, and inhibits the expressions of Bax, Cleaved caspase-3 and -9. Salvianolic acid D reduces the expression levels of TLR4, MyD88 and TRAF6 proteins both in vitro and in vivo, and significantly inhibits the nuclear translocation of NF-κB. Salvianolic acid D inhibits the cytoplasmic translocation of HMGB1. Salvianolic acid D suppresses inflammatory responses and alleviates cerebral ischemia-reperfusion injury. Salvianolic acid D serves as a potential antiplatelet active component .
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Salvianolic acid F
Salvianolic acid F
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1 Cited Publications
Cat. No.: HY-125847
CAS No.: 158732-59-3
Purity:  99.72%
Category:  

Stilbenes Labiatae Samanea saman (Jacq.) Merr. Phenols Polyphenols Plants Disease Research Fields Cancer

Target:  

Ras PI3K Akt Caspase Apoptosis Bcl-2 Family NF-κB MMP

Salvianolic acid F is a KRAS inhibitor, especially for KRAS G12D. Salvianolic acid F inhibits NF-kB, MMP-9, and NO simultaneously. Salvianolic acid F inhibits cancer cell growth, invasion, and migration and induces apoptosis via the EP300/PI3K/AKT pathway in vitro. Salvianolic acid F inhibits the growth of KRAS-dependent lung cancer cells via the PI3K/AKT signaling pathway in vivo. Salvianolic acid F can be used in the research of various cancers, including KRAS G12D-driven non-small cell lung cancer (NSCLC) and ovarian cancer .
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Salvianolic acid D (Standard)
Salvianolic acid D (Standard)
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Cat. No.: HY-N0320R
CAS No.: 142998-47-8
Category:  

Labiatae Samanea saman (Jacq.) Merr. Lignans Phenols Polyphenols Phenylpropanoids Plants

Target:  

Reference Standards Others

Salvianolic acid D (Standard) is the analytical standard of Salvianolic acid D. This product is intended for research and analytical applications. Salvianolic acid D, isolated from Salvia miltiorrhiza, is a potential antiplatelet activity compound .
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