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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
18 Results for "
Sema3A
" in MedChemExpress (MCE) Product Catalog:
Products (18)
18 Results for "Sema3A" in MCE Product Catalog:
8
8 Publications Verification
Synonyms: SKF 29044
Target:
Parbendazole (SKF‑29044) is an orally active benzimidazole carbamate compound with multiple biological activities. Parbendazole binds to free tubulin and inhibits microtubule polymerization; it also activates the JNK/c‑Jun signaling axis and upregulates the expression of the downstream axonal repulsion factor Sema3A. Parbendazole upregulates KAL-1 mRNA expression, reduces nerve growth factor levels, and promotes the terminal differentiation of normal human epidermal keratinocytes. Parbendazole induces apoptosis in differentiated acute myeloid leukemia monocytes and exerts antileukemic activity in a mouse xenograft model of acute myeloid leukemia. Parbendazole exhibits broad-spectrum anthelmintic activity against various animal nematodes. Parbendazole is used in research related to acute myeloid leukemia and parasitic infections [3] .
2
2 Cited Publications
Cat. No.: HY-P74566
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: Sema3A; Sema III; Prev. SemaD; Semaphorin D; HSema-I; Semaphorin L; Coll-1; Collapsin 1; Sema1; HSema-III; SemD; SemaIII; Sema Domain, Immunoglobulin Domain (Ig), Short Basic Domain, Secreted, (Semaphorin) 3A; COLL1; Semaphorin III; SemaL; Semaphorin-3A;
Species:
Mouse
Source:
HEK293
1
1 Cited Publications
Cat. No.: HY-P71564
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: Sema3A; Sema III; Prev. SemaD; Semaphorin D; HSema-I; Semaphorin L; Coll-1; Collapsin 1; Sema1; HSema-III; SemD; SemaIII; Sema Domain, Immunoglobulin Domain (Ig), Short Basic Domain, Secreted, (Semaphorin) 3A; COLL1; Semaphorin III; SemaL; Semaphorin-3A;
Species:
Rat
Source:
E. coli
Target:
Research Areas:
TCS1105 is a benzodiazepine ligand with agonist for α2-subunit containing GABAA receptors and antagonist for α1-subunit containing GABAA receptors. TCS1105 reduces anxiety-like behavior in mice. TCS1105 enhances offensive behavior and social dominance. TCS1105 blocks Sema3A induced AGC (axonal growth cones) collapse in a concentration-dependent fashion .
Cat. No.: HY-RS12650
Target:
Research Areas:
SEMA3A Human Pre-designed siRNA Set A contains three designed siRNAs for SEMA3A gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS17258
Target:
Research Areas:
Sema3a Mouse Pre-designed siRNA Set A contains three designed siRNAs for Sema3a gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS23712
Target:
Research Areas:
Sema3a Rat Pre-designed siRNA Set A contains three designed siRNAs for Sema3a gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P992302
Target:
Research Areas:
Anti-SEMA3A Antibody is a monoclonal antibody targeting SEMA3A. It can be used in ELISA, FACS, and functional assays. For isotype controls of Anti-SEMA3A Antibody, please refer to Human IgG4 (S228P) kappa, Isotype Control (HY-P99003).
Cat. No.: HY-115364R
CAS No.: 14255-87-9
Synonyms: SKF 29044 (Standard)
Parbendazole (Standard) (SKF 29044 (Standard)) is the analytical standard of Parbendazole (HY-115364). This product is intended for research and analytical applications. Parbendazole (SKF‑29044) is an orally active benzimidazole carbamate compound with multiple biological activities. Parbendazole binds to free tubulin and inhibits microtubule polymerization; it also activates the JNK/c‑Jun signaling axis and upregulates the expression of the downstream axonal repulsion factor Sema3A. Parbendazole upregulates KAL-1 mRNA expression, reduces nerve growth factor levels, and promotes the terminal differentiation of normal human epidermal keratinocytes. Parbendazole induces apoptosis in differentiated acute myeloid leukemia monocytes and exerts antileukemic activity in a mouse xenograft model of acute myeloid leukemia. Parbendazole exhibits broad-spectrum anthelmintic activity against various animal nematodes. Parbendazole is used in research related to acute myeloid leukemia and parasitic infections [3] .
Cat. No.: HY-115364S
CAS No.: 1613439-58-9
Synonyms: SKF 2904-d3
Parbendazole-d3 (SKF 2904-d3) is the deuterated-labeled Parbendazole (HY-115364). Parbendazole (SKF‑29044) is an orally active benzimidazole carbamate compound with multiple biological activities. Parbendazole binds to free tubulin and inhibits microtubule polymerization; it also activates the JNK/c‑Jun signaling axis and upregulates the expression of the downstream axonal repulsion factor Sema3A. Parbendazole upregulates KAL-1 mRNA expression, reduces nerve growth factor levels, and promotes the terminal differentiation of normal human epidermal keratinocytes. Parbendazole induces apoptosis in differentiated acute myeloid leukemia monocytes and exerts antileukemic activity in a mouse xenograft model of acute myeloid leukemia. Parbendazole exhibits broad-spectrum anthelmintic activity against various animal nematodes. Parbendazole is used in research related to acute myeloid leukemia and parasitic infections [3] .
Cat. No.: HY-P700297
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Sema3A; Sema III; Prev. SemaD; Semaphorin D; HSema-I; Semaphorin L; Coll-1; Collapsin 1; Sema1; HSema-III; SemD; SemaIII; Sema Domain, Immunoglobulin Domain (Ig), Short Basic Domain, Secreted, (Semaphorin) 3A; COLL1; Semaphorin III; SemaL; Semaphorin-3A;
Species:
Human
Source:
HEK293
Cat. No.: HY-P70797
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Sema3A; Sema III; Prev. SemaD; Semaphorin D; HSema-I; Semaphorin L; Coll-1; Collapsin 1; Sema1; HSema-III; SemD; SemaIII; Sema Domain, Immunoglobulin Domain (Ig), Short Basic Domain, Secreted, (Semaphorin) 3A; COLL1; Semaphorin III; SemaL; Semaphorin-3A;
Species:
Human
Source:
HEK293
Cat. No.: HY-P704874
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Sema3A; Sema III; Prev. SemaD; Semaphorin D; HSema-I; Semaphorin L; Coll-1; Collapsin 1; Sema1; HSema-III; SemD; SemaIII; Sema Domain, Immunoglobulin Domain (Ig), Short Basic Domain, Secreted, (Semaphorin) 3A; COLL1; Semaphorin III; SemaL; Semaphorin-3A;
Species:
Human
Source:
HEK293
Cat. No.: HY-P87394A
Synonyms: SemaD, Sema3A, Semaphorin-3A, Semaphorin III, Sema III
Cat. No.: HY-P78350Y
Purity: ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: Sema3A; Sema III; Prev. SemaD; Semaphorin D; HSema-I; Semaphorin L; Coll-1; Collapsin 1; Sema1; HSema-III; SemD; SemaIII; Sema Domain, Immunoglobulin Domain (Ig), Short Basic Domain, Secreted, (Semaphorin) 3A; COLL1; Semaphorin III; SemaL; Semaphorin-3A;
Species:
Mouse
Source:
HEK293
Cat. No.: HY-P78350
Purity: ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: Sema3A; Sema III; Prev. SemaD; Semaphorin D; HSema-I; Semaphorin L; Coll-1; Collapsin 1; Sema1; HSema-III; SemD; SemaIII; Sema Domain, Immunoglobulin Domain (Ig), Short Basic Domain, Secreted, (Semaphorin) 3A; COLL1; Semaphorin III; SemaL; Semaphorin-3A;
Species:
Mouse
Source:
HEK293
Cat. No.: HY-115364A
CAS No.: 83601-81-4
Synonyms: SKF 29044 hydrochloride
Parbendazole hydrochloride (SKF‑29044 hydrochloride) is an orally active benzimidazole carbamate compound with multiple biological activities. Parbendazole hydrochloride binds to free tubulin and inhibits microtubule polymerization; it also activates the JNK/c‑Jun signaling axis and upregulates the expression of the downstream axonal repulsion factor Sema3A. Parbendazole hydrochloride upregulates KAL-1 mRNA expression, reduces nerve growth factor levels, and promotes the terminal differentiation of normal human epidermal keratinocytes. Parbendazole hydrochloride induces apoptosis in differentiated acute myeloid leukemia monocytes and exerts antileukemic activity in a mouse xenograft model of acute myeloid leukemia. Parbendazole hydrochloride exhibits broad-spectrum anthelmintic activity against various animal nematodes. Parbendazole hydrochloride is used in research related to acute myeloid leukemia and parasitic infections [3] .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
