30 Results for "

TTP

" in MedChemExpress (MCE) Product Catalog:
Products (30)

30 Results for "TTP" in MCE Product Catalog:

Referencia número: HY-P60128
No. CAS: 943235-73-2
Target:  

Inhibitory Antibodies

Áreas de investigación:  

Others

TTP is a generic surrogate peptide. TTP can be used for quantitative analysis of a recombinanthuman immunoglobulin G1 (hIgG1) in rat serum .
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17
17 Publications Verification
Referencia número: HY-50682
No. CAS: 603148-36-3
Synonyms: TTP488; PF-04494700
Target:  

Amyloid-β

Áreas de investigación:  

Neurological Disease Cancer

Azeliragon (TTP488) is an orally bioavailable inhibitor of the receptor for advanced glycation end products (RAGE) in development as a potential treatment to slow disease progression with mild Alzheimer’s disease (AD) . Azeliragon also can cross the blood-brain barrier (BBB) .
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2
2 Cited Publications
Referencia número: HY-P99227
No. CAS: 915810-67-2
Synonyms: ALX-0681; ALX-0081

Áreas de investigación:  

Cardiovascular Disease

Caplacizumab (His Tag) is a humanized anti-von Willebrand factor (vWF) nanobody. Caplacizumab (His Tag) inhibits the binding of vWF with platelet glycoprotein (GP) Ibα. Caplacizumab (His Tag) inhibits the vWF-mediated platelet adhesion and prevents further microthrombi formation. Caplacizumab (His Tag) can be used for the research of thrombotic thrombocytopenic purpura (TTP) .
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2 Cited Publications
Referencia número: HY-15479
No. CAS: 329907-28-0
Pureza:  98.40%
Target:  

Casein Kinase

Áreas de investigación:  

Inflammation/Immunology Cancer

TTP 22 is a potent CK2 inhibitor, with an IC50 of 100 nM and a Ki of 40 nM.
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2
2 Cited Publications
Referencia número: HY-124806
No. CAS: 950225-08-8
Pureza:  99.90%
Áreas de investigación:  

Infection

TTP-8307 is a potent inhibitor of the replication of several rhino- and enteroviruses. TTP-8307 inhibits coxsackievirus B3 (CVB3; EC50=1.2 μM) and poliovirus by interfering with the synthesis of viral RNA. TTP-8307 exerts antiviral activity through oxysterol-binding protein (OSBP) .
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2
2 Cited Publications
Referencia número: HY-W009163
No. CAS: 957-75-5
Áreas de investigación:  

Others

5-Bromouridine is a brominated uridine nucleoside. The triphosphate form of 5-Bromouridine, 5BrdUTP, can substitute for TTP as a substrate for DNA polymerase and be incorporated into nascent DNA strands, rendering the resulting 5-bromouridine-labeled DNA photosensitive to 300 nm UV irradiation; upon UV irradiation, the 5BrdU signal decreases and dU is generated, accompanied by DNA strand breaks and cross-link formation. 5-Bromouridine is useful for studies on nucleoside structure and halogenated nucleoside-labeled nucleic acids .
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Referencia número: HY-170224
dNTP Mixture,10 mM Solution,PCR Grade is a PCR-grade 10 mM mixed solution of natural deoxynucleoside triphosphates (dATP, dCTP, dGTP, TTP), which is suitable for various biological reactions including DNA amplification and reverse transcription .
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Referencia número: HY-147254
No. CAS: 859525-02-3
Pureza:  99.80%
Synonyms: TTP-399
Target:  

Glucokinase

Áreas de investigación:  

Metabolic Disease

Cadisegliatin (TTP-399) is a potential, orally active liver-selective glucokinase (GK) activator. Cadisegliatin has antihyperglycaemic activity. Cadisegliatin can be used for the research of type 2 diabetes .
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Referencia número: HY-W035133
No. CAS: 14527-51-6
Synonyms: 5,10,15,20-Tetra-p-tolyl-21H,23H-porphine
5,10,15,20-Tetrakis(p-tolyl)porphyrin (TTP) is an organic compound belonging to the class of porphyrins, a cyclic molecule composed of four pyrrole rings linked together. TTP is a synthetic porphyrin commonly used as a sensitizer for dye-sensitized solar cells and a catalyst for organic reactions. Due to its unique structure, TTP has a series of interesting properties, including at specific wavelengths and its potential as a catalyst for various chemical reactions. In dye-sensitized solar cells, TTPs help convert sunlight into electricity by absorbing photons and transferring electrons to the semiconductor layer of the device. In organic chemistry, TTP is often used as a catalyst for various organic compounds in reactions such as oxidation and reduction. Its ability to selectively bind certain substrates makes it a useful tool for synthesizing complex molecules and studying their properties.
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Referencia número: HY-50682S
Synonyms: TTP488-d9; PF-04494700-d9
Azeliragon-d9 (TTP488-d9) is the deuterium labeled Azeliragon (HY-50682). Azeliragon (TTP488) is an orally bioavailable inhibitor of the receptor for advanced glycation end products (RAGE) in development as a potential treatment to slow disease progression with mild Alzheimer’s disease (AD) . Azeliragon also can cross the blood-brain barrier (BBB) .
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Referencia número: HY-147036
No. CAS: 825647-78-7
Target:  

Orthopoxvirus

Áreas de investigación:  

Infection

TTP-6171 is a non-covalent inhibitor of Monkeypox virus I7L protease, and it can be used for research on poxvirus infections .
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Referencia número: HY-137613C
Target:  

HIV

Áreas de investigación:  

Infection

Rp-TTPαS (tetrasodium) is the Rp-isomer of TTPαS (tetrasodium). Rp-TTPαS (tetrasodium) incorporate with HIV-1 reverse transcriptase (HIV-1 RT) with HIV-1 RT with large phosphorothioate elemental effects .
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Referencia número: HY-137613
No. CAS: 83199-32-0
Target:  

HIV

Áreas de investigación:  

Infection Inflammation/Immunology

Sp-TTPαS is a competitivesterile alpha motif and HD domain containing protein 1 (SAMHD1) hydrolysis inhibitor. Sp-TTPαS competitively inhibits SAMHD1 triphosphohydrolase activity with a Ki value of 46 µM .
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Referencia número: HY-170238
dNTP Mixture,25 mM Solution,PCR Grade is a PCR-grade 25 mM mixed solution of natural deoxynucleoside triphosphates (dATP, dCTP, dGTP, TTP), which is suitable for various biological reactions including DNA amplification and reverse transcription .
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Referencia número: HY-50682A
No. CAS: 1284150-65-7
Synonyms: TTP488 dihydrochloride; PF-04494700 dihydrochloride
Target:  

Amyloid-β

Áreas de investigación:  

Neurological Disease Cancer

Azeliragon dihydrochloride (TTP488) is an orally bioavailable inhibitor of the receptor for advanced glycation end products (RAGE) in development as a potential treatment to slow disease progression with mild Alzheimer’s disease (AD) . Azeliragon dihydrochloride also can cross the blood-brain barrier (BBB) .
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Referencia número: HY-50682R
No. CAS: 603148-36-3
Synonyms: TTP488 (Standard); PF-04494700 (Standard)
Áreas de investigación:  

Neurological Disease Cancer

Azeliragon (Standard) is the analytical standard of Azeliragon. This product is intended for research and analytical applications. Azeliragon (TTP488) is an orally bioavailable inhibitor of the receptor for advanced glycation end products (RAGE) in development as a potential treatment to slow disease progression with mild Alzheimer’s disease (AD) . Azeliragon also can cross the blood-brain barrier (BBB) .
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Referencia número: HY-RS12832
Áreas de investigación:  

Others

SH3BP4 Human Pre-designed siRNA Set A contains three designed siRNAs for SH3BP4 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Referencia número: HY-137613A
Target:  

HIV

Áreas de investigación:  

Infection Inflammation/Immunology

Sp-TTPαS tetrasodium is a competitivesterile alpha motif and HD domain containing protein 1 (SAMHD1) hydrolysis inhibitor. Sp-TTPαS tetrasodium competitively inhibits SAMHD1 triphosphohydrolase activity with a Ki value of 46 µM .
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Referencia número: HY-RS16040
Áreas de investigación:  

Others

ZFP36 Human Pre-designed siRNA Set A contains three designed siRNAs for ZFP36 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Referencia número: HY-P4272
No. CAS: 21866-90-0
Target:  

Inhibitory Antibodies

Áreas de investigación:  

Others

Tetraproline is a fragment sequence in tristetraprolin (TTP). Recruitment of the 4EHP-GYF2 cap-binding complex to tetraproline motifs of tristetraprolin promotes repression and degradation of mRNAs with AU-rich elements .
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