5 Results for "

acetic acid-induced writhing mouse models

" in MedChemExpress (MCE) Product Catalog:
Products (5)

5 Results for "acetic acid-induced writhing mouse models" in MCE Product Catalog:

2
2 Cited Publications
Cat. No.: HY-N0745
CAS No.: 94596-28-8
Senkyunolide I is an orally active, blood-brain barrier-permeable metabolite of Z-ligustilide (HY-N0401A) . Senkyunolide I is isolated from Ligusticum chuanxiong. Senkyunolide I upregulates p-Erk1/2 and Nrf2/HO-1, and inhibits Caspase 3. Senkyunolide I alleviates Apoptosis. Senkyunolide I increases the pain threshold in mice and reduces acetic acid-induced writhing responses in mice. Senkyunolide I improves neurological deficits, reduces infarct volume and alleviates cerebral edema in rats with focal cerebral ischemia-reperfusion injury. Senkyunolide I protects renal function and structural integrity in a mouse model of renal ischemia-reperfusion injury. Senkyunolide I is applicable to research related to focal cerebral ischemia-reperfusion injury, migraine, and renal ischemia-reperfusion injury .
loading...
    loading...
Cat. No.: HY-123452
CAS No.: 83674-78-6
Target:  

Others

Research Areas:  

Neurological Disease

SCH 30497 is a potent and orally active analgesic agent. SCH 30497 exhibits analgesic activity in the rat yeast-induced paw pain model, the mouse acetic acid-induced writhing test, and the squirrel monkey electric shock titration test. SCH 30497 can be used in pain research .
loading...
    loading...
Cat. No.: HY-101670
CAS No.: 70991-61-6
Synonyms: (Rac)-M-5011
MTPPA ((Rac)-M-5011) is an orally active anti-inflammatory, analgesic and anti-rheumatic compound. MTPPA mediates the inhibition of prostaglandin biosynthesis. MTPPA acts as a four-point tetrahedral organophosphonate bridging ligand. MTPPA can be used in research related to inflammation, pain and adjuvant arthritis .
loading...
    loading...
Cat. No.: HY-182782
CAS No.: 1179703-17-3
Target:  

Adenosine Receptor

Research Areas:  

Neurological Disease

Analgesic agent-4 is an adenosine A3AR ligand with analgesic/antinociceptive activity. Analgesic agent-4 inhibits writhing responses in mice and exhibits dose-dependent activity in the acetic acid (HY-Y0319)-induced mouse writhing model. Analgesic agent-4 can be used in the research of pain-related diseases .
loading...
    loading...
Cat. No.: HY-183773
Target:  

Opioid Receptor

Research Areas:  

Neurological Disease

KOR agonist-9 is a selective kappa opioid receptor (KOR) agonist with an EC50 of 1.41 nM. KOR agonist-9 exhibits >125-fold selectivity over μ/δ-opioid receptors. KOR agonist-9 antinociceptive and antipruritic effects in mice. KOR agonist-9 can be used for the research of pain, pruritus .
loading...
    loading...