96 Results for "

anti-tussive

" in MedChemExpress (MCE) Product Catalog:
Products (96)

96 Results for "anti-tussive" in MCE Product Catalog:

4
4 Cited Publications
Cat. No.: HY-B2215
CAS No.: 36304-84-4
Dimemorfan phosphate is a sigma 1 receptor agonist, used as a potent antitussive.
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3
3 Cited Publications
Cat. No.: HY-N0808
CAS No.: 76-22-2
Synonyms: (±)-Camphor
Camphor ((±)-Camphor) is a topical anti-infective and anti-pruritic and internally as a stimulant and carminative. However, Camphor is poisonous when ingested. Antiviral, antitussive, and anticancer activities . Camphor is a TRPV3 agonist .
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2
2 Cited Publications
Cat. No.: HY-13716
CAS No.: 128-62-1
Purity:  99.98%
Synonyms: (S,R)-Noscapine
Noscapine ((S,R)-Noscapine) is an orally active phthalideisoquinoline alkaloid with potent antitussive. Noscapine exerts its antitussive effects by activating sigma opioid receptors and is a non-competitive Bradykinin inhibitor. Noscapine disrupts microtubule dynamics, induces mitotic arrest and apoptosis. Noscapine possesses anticancer, neuroprotective, anti-inflammatory activities, and can cross the blood-brain barrier .
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2
2 Cited Publications
Cat. No.: HY-13716A
CAS No.: 912-60-7
Purity:  99.87%
Synonyms: (S,R)-Noscapine hydrochloride
Noscapine ((S,R)-Noscapine) hydrochloride is an orally active phthalideisoquinoline alkaloid with potent antitussive. Noscapine hydrochloride exerts its antitussive effects by activating sigma opioid receptors and is a non-competitive Bradykinin inhibitor. Noscapine hydrochloride disrupts microtubule dynamics, induces mitotic arrest and apoptosis. Noscapine hydrochloride possesses anticancer, neuroprotective, anti-inflammatory activities, and can crosse the blood-brain barrier .
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1
1 Cited Publications
Cat. No.: HY-N0829
CAS No.: 10376-48-4
Shionone is the major triterpenoid isolated from Aster tataricus, has anti-tussive, anti-inflammatory activities . Shionone possesses a unique six-membered tetracyclic skeleton and 3-oxo-4-monomethyl structure .
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1
1 Cited Publications
Cat. No.: HY-121685A
CAS No.: 1449686-84-3
Purity:  99.98%
Target:  

Potassium Channel

Research Areas:  

Neurological Disease

Tipepidine hydrochloride reversibly inhibits dopamine (DA) D2 receptor-mediated GIRK currents (IDA(GIRK)) with an IC50 of 7.0 μM. Tipepidine hydrochloride subsequently activates VTA dopamine neuron . Tipepidine hydrochloride, a non-narcotic antitussive, exerts an antidepressant-like effect .
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1
1 Cited Publications
Cat. No.: HY-N2120
CAS No.: 88509-91-5
Dichotomitin is an isoflavonoid compound isolated from the rhizomes of Belamcanda chinensis. Dichotomitin exhibits antioxidant activity, alleviates oxidative stress, reduces intracellular reactive oxygen species (ROS) levels, and upregulates the expression of SOD1, SOD2 and CAT. Dichotomitin increases ALP activity while upregulating the expression of RUNX2, OPN and OCN. Dichotomitin has antitussive activity and helps improve symptoms of upper respiratory tract infections .
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1
1 Cited Publications
Cat. No.: HY-B0505
CAS No.: 119637-67-1
Synonyms: BBR-2173
Target:  

Opioid Receptor

Research Areas:  

Neurological Disease Cancer

Moguisteine???(BBR-2173) is an antitussive compound but has no significant affinity for opiate receptors.
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Cat. No.: HY-136026
CAS No.: 1621164-74-6
Purity:  99.94%
Synonyms: BLU-5937
Target:  

P2X Receptor

Research Areas:  

Inflammation/Immunology

Camlipixant (BLU-5937) a potent, selective, non-competitive and orally active P2X3 homotrimeric receptor antagonist with an IC50 of 25 nM against hP2X3 homotrimeric. Camlipixant shows potent anti-tussive effect and no taste alteration. Camlipixant can be used for the research of unexplained, refractory chronic cough .
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Cat. No.: HY-B1551
CAS No.: 104-31-4
Synonyms: Benzononatine
Target:  

Sodium Channel

Research Areas:  

Neurological Disease

Benzonatate (Benzononatine) is an orally active and non-narcotic peripheral antitussive agent. Benzonatate is a reversible voltage-gated Na + channels inhibitor. Benzonatate dampens the activity of cough stretch receptors .
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Cat. No.: HY-121388
CAS No.: 577-27-5
Purity:  ≥98.0%
Synonyms: (+)-Ledol
Ledol ((+)-Ledol) is an antifungal agent isolated from the volatile oil components of Rhododendron tomentosum. Ledol also acts as an expectorant and antitussive, while it can cause adverse reactions such as dizziness, nausea and vomiting .
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Cat. No.: HY-N1255
CAS No.: 6451-73-6
Synonyms: (-)-Scoulerine; Discretamine
Scoulerine ((-)-Scoulerine; Discretamine) hydrochloride is a multi-target inhibitor with anti-tumor and antioxidant activities. Scoulerine mainly targets the PI3K/Akt/mTOR signaling axis and α1D-adrenergic receptor, disrupts microtubule structure, and induces cell cycle arrest and apoptosis. Scoulerine effectively inhibits mitochondrial dehydrogenase activity, targets GABA receptors and BACE1, and suppresses the proliferation, migration, invasion, epithelial-mesenchymal transition and stem cell properties of cancer cells. Scoulerine also exhibits multiple pharmacological activities including anti-Plasmodium falciparum, antibacterial, antiemetic and antitussive effects, and regulates endoplasmic reticulum stress and mitochondrial function (modulates Bax, Bcl-2 and cytochrome c). Scoulerine is applicable to research related to leukemia, ovarian cancer, and colorectal cancer .
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Cat. No.: HY-B1895
CAS No.: 99291-25-5
Synonyms: (S)-(-)-Dropropizine; DF-526
Levodropropizine (DF-526) is an orally active histamine receptor inhibitor, Levodropropizine is an effective and very well tolerated peripheral antitussive agent .
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Cat. No.: HY-B1038
CAS No.: 18598-63-5
Target:  

Endogenous Metabolite

Research Areas:  

Inflammation/Immunology

L-Cysteine methyl ester hydrochloride is an antitussive, phlegmolytic agent used to relieve breathing difficulties caused by large amounts of phlegm. L-Cysteine methyl ester hydrochloride is a copper corrosion inhibitor used in various industrial studies .
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Cat. No.: HY-134004
CAS No.: 77-23-6
Purity:  98.91%
Synonyms: Carbetapentane
Pentoxyverine (Carbetapentane) is an orally active sigma-1 receptor agonist, with Kis of 41 nM, 894 nM and 75 nM for σ1, σ2 and guinea-pig brain membran σ1, respectively. Pentoxyverine is a muscarinic antagonist. Pentoxyverine is a potent antitussive, anticonvulsant, and spasmolytic agent. Pentoxyverine can be used for inhibiting bronchial interceptor, weakening of cough reflex, bronchial smooth muscle relaxation and reduction of airway resistance .
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Cat. No.: HY-N1377
CAS No.: 10176-66-6
Synonyms: Lysionotin
Nevadensin (Lysionotin), a natural flavonoid, is a selective human carboxylesterase 1 (hCE1) inhibitor with an IC50 of 2.64 μM. Nevadensin is more selective for hCE1 than hCE2 (IC50 of 132.8 μM). Nevadensin can induce apoptosis and DNA damage in cancer cells. Nevadensin has a variety of pharmacological effects such as anti-inflammatory, anti-tumour, anti-hypertensive, anti-tubercular, antitussive, antioxidant and anti-microbial activities .
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Cat. No.: HY-B1055
CAS No.: 23142-01-0
Synonyms: Carbetapentane citrate
Pentoxyverine (Carbetapentane) citrate is an orally active and blood-brain barrier permeability sigma-1 receptor agonist, with Kis of 41 nM, 894 nM and 75 nM for σ1, σ2 and guinea-pig brain membrane σ1, respectively. Pentoxyverine citrate is a muscarinic antagonist. Pentoxyverine citrate is a potent antitussive, anticonvulsant, and spasmolytic agent. Pentoxyverine citrate can be used for inhibiting bronchial interceptor, weakening of cough reflex, bronchial smooth muscle relaxation and reduction of airway resistance .
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Cat. No.: HY-A0161A
CAS No.: 511-13-7
Synonyms: Clofedanol hydrochloride; Calmotusin hydrochloride; NSC 113595 hydrochloride
Target:  

Others

Research Areas:  

Infection

Chlophedianol (Clofedanol) hydrochloride is an orally active and potent antitussive agent. Chlophedianol hydrochloride can be used for the research of acute cough due to upper respiratory tract infections (URIs) .
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Cat. No.: HY-B2078A
CAS No.: 10402-53-6
Target:  

Neurokinin Receptor

Research Areas:  

Inflammation/Immunology

Eprazinone dihydrochloride is a gent with mucolytic, secretolytic, antitussive, and bronchial antispasmodic properties. Eprazinone dihydrochloride is a neurokinin 1 receptor (NK1R) ligand. Eprazinone dihydrochloride has the potential for chronic bronchitis treatment that improved pulmonary function and arterial partial pressure of oxygen .
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Cat. No.: HY-118545
CAS No.: 18109-80-3
Target:  

STAT

Research Areas:  

Inflammation/Immunology Cancer

Butamirate is an orally active antitussive agent that acts centrally through the receptors in the brainstem. Butamirate also reduces the resistance in the airways by inhibiting bronchospasm and anti-inflammatory effect. Butamirate inhibits glioblastoma (GBM) growth and STAT3 activity. Butamirate can be used for the study of glioblastoma .
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