2 Results for "

anticodon stem loop

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "anticodon stem loop" in MCE Product Catalog:

Cat. No.: HY-W244398
CAS No.: 13239-97-9
Domaines de recherche:  

Others

2-Thiocytidine is a natural thionucleoside in prokaryotic tRNA, which is biosynthesized under the catalysis of intracellular sulfur transferase systems and possesses multiple activities such as metal coordination and nucleic acid conformation regulation. 2-Thiocytidine forms stable Zn 2+ and Cd 2+ complexes via its (C2) S group, with partial involvement of N3; metal binding acidifies the deprotonation process of (C4) NH2. 2-Thiocytidine can be used in related research in various fields including nanotechnology and click chemistry for interstrand DNA crosslinking .
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Cat. No.: HY-169810
CAS No.: 849658-87-3
Target:  

Antibiotic Bacterial

Domaines de recherche:  

Infection

PKZ18 is an antibiotic and inhibits bacterial growth, with MIC values of 32-64 μg/mL against most Gram-positive bacteria. PKZ18 inhibits in vivo transcription and translation of glycyl-tRNA synthetase mRNA. PKZ18 selectively targets stem I specifier loops in Gram-positive bacteria and directly reduces T-box transcriptional read-through of the associated genes. PKZ18 prevents the codon-anticodon reading required for tRNA binding and is refractory to resistance .
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