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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
45 Results for "
brain-derived neurotrophic factor
" in MedChemExpress (MCE) Product Catalog:
Products (45)
45 Results for "brain-derived neurotrophic factor" in MCE Product Catalog:
21
21 Publications Verification
Cat. No.: HY-W013372
CAS No.: 38183-03-8
Category:
Flavonoids Flavones Phenols Polyphenols Plants Umbelliferae Carphephorus corymbosus (Nutt.) Torr. & A.Gray
Target:
15
15 Cited Publications
Cat. No.: HY-P7116A
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: BDNF; Abrineurin; brain derived neurotrophic factor; brain-derived neurotrophic factor Preproprotein Isoform 2; ProBDNF; brain-derived neurotrophic factor Isoform 1; neurotrophic factor BDNF Precursor Form; ANON2; brain-derived neurotrophic factor; BULN2
Species:
Mouse
Rat
Human
Source:
E. coli
5
5 Cited Publications
Target:
Research Areas:
PI3K/Akt/CREB activator 1 (compound AE-18) is a potent, orally active PI3K/Akt/CREB activator. PI3K/Akt/CREB activator 1 promotes neuronal proliferation, induced differentiation of Neuro-2a cells into a neuron-like morphology, and accelerated the establishment of axon-dendrite polarization of primary hippocampal neurons through upregulating brain-derived neurotrophic factor via the PI3K/Akt/CREB pathway. PI3K/Akt/CREB activator 1 can be used in research of vascular dementia (VaD) .
3
3 Cited Publications
Cat. No.: HY-P74383
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: BDNF; Abrineurin; brain derived neurotrophic factor; brain-derived neurotrophic factor Preproprotein Isoform 2; ProBDNF; brain-derived neurotrophic factor Isoform 1; neurotrophic factor BDNF Precursor Form; ANON2; brain-derived neurotrophic factor; BULN2
Species:
Mouse
Source:
HEK293
1
1 Cited Publications
Synonyms: Diphosphofructose; Esafosfan; FDP
Category:
Cardiovascular Disease Human Gut Microbiota Metabolites Microorganisms Ketones, Aldehydes, Acids Endogenous metabolite Disease Research Fields
Target:
1
Category:
Pelargonium hortorum Bailey Liliaceae Neurological Disease Anemarrhena asphodeloides Bunge Plants Disease Research Fields Geraniaceae Steroids
Target:
1
1 Cited Publications
Target:
Research Areas:
HIOC is a potent and selective activator of TrkB (tropomyosin related kinase B) receptor. HIOC can pass the blood-brain and blood-retinal barriers.HIOC activates TrkB/ERK pathway and decreases neuronal cell apoptosis. HIOC attenuates early brain injury after SAH (subarachnoid hemorrhage). HIOC shows protective activity in an animal model for light-induced retinal degeneration .
1
1
1 Cited Publications
Cat. No.: HY-P700158AF
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: BDNF; Abrineurin; brain derived neurotrophic factor; brain-derived neurotrophic factor Preproprotein Isoform 2; ProBDNF; brain-derived neurotrophic factor Isoform 1; neurotrophic factor BDNF Precursor Form; ANON2; brain-derived neurotrophic factor; BULN2
Species:
Rat
Mouse
Human
Source:
E. coli
1
1 Cited Publications
Cat. No.: HY-W097570
CAS No.: 38006-08-5
Target:
Research Areas:
Sulfamonomethoxine sodium is an orally active broad-spectrum synthetic sulfonamide antibiotic that inhibits dihydropteroate synthetase. Sulfamonomethoxine sodium increases blood glucose levels, induces anxiety-related activities and impairs spatial learning and memory. Sulfamonomethoxine sodium can be used for the research of anxiety, spatial memory impairment, colisepticemia, salmonellosis, and staphylococcus infection .
1
Cat. No.: HY-N2055
CAS No.: 19895-95-5
Target:
Synonyms: NSI-189
Target:
Research Areas:
Amdiglurax (NSI-189) is an orally active chemical entity with enhanced neurogenic activity. Amdiglurax up-regulates neurogenic factors such as BDNF (brain derived-neurotrophic factor) and SCF. Amdiglurax exhibits anti-depressant effect. Amdiglurax enhances synaptic plasticity and reduces cognitive dysfunction. Amdiglurax holds potential for psychiatric disorder research .
Target:
Research Areas:
HBT1 is an effective AMPA receptor AMPA-R potentiator. HBT1 specifically binds to the ligand-binding domain (LBD) of AMPAR and enhances receptor activity only when AMPA is present., HBT1 has almost no agonistic effect (i.e., reaching the optimal concentration, and then the efficacy decreases as the concentration continues to increase) compared with traditional AMPA-R potentiator, avoiding the bell-shaped reaction of brain-derived neurotrophic factor (BDNF) production in primary neurons. HBT1 can be applicable to a wider range of neurological and psychiatric diseases (such as depression, Alzheimer's disease, etc.) .
Cat. No.: HY-N3298
CAS No.: 23971-42-8
Synonyms: NSI-189 phosphate
Target:
Research Areas:
Amdiglurax (NSI-189) phosphate is an orally active chemical entity with enhanced neurogenic activity. Amdiglurax phosphate up-regulates neurogenic factors such as BDNF (brain derived-neurotrophic factor) and SCF. Amdiglurax phosphate exhibits anti-depressant effect. Amdiglurax enhances synaptic plasticity and reduces cognitive dysfunction. Amdiglurax phosphate holds potential for psychiatric disorder research .
Cat. No.: HY-W013372R
CAS No.: 38183-03-8
Category:
Flavonoids Flavones Phenols Polyphenols Plants Umbelliferae Carphephorus corymbosus (Nutt.) Torr. & A.Gray
Target:
Target:
Research Areas:
BNN-20 is a synthetic microneurotrophin that mimics brain-derived neurotrophic factor (BDNF) and exhibits area-specific pleiotropic neuroprotective and pro-neurogenic effects. BNN-20 can be utilized in research related to Parkinson's disease .
Cat. No.: HY-102091
CAS No.: 169209-63-6
Synonyms: (2R,4R)-4-Aminopyrrolidine-2,4-dicarboxylic acid
Target:
Research Areas:
(2R,4R)-APDC is a group II metabotropic glutamate receptor (mGluR) agonist. (2R,4R)-APDC affects cell proliferation by inhibiting glutamate release, enhancing motor responses produced by D1 receptor activation, or reducing brain-derived neurotrophic factor (BDNF) levels. (2R,4R)-APDC can be used in the study of epilepsy and other neurological diseases .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
