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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
43 Results for "
bromination
" in MedChemExpress (MCE) Product Catalog:
Products (43)
43 Results for "bromination" in MCE Product Catalog:
1
Category:
Target:
1
1 Cited Publications
Cat. No.: HY-15929
CAS No.: 14348-40-4
Synonyms: 2,4,6-Tribromo-3-hydroxybenzoic acid
Cat. No.: HY-42487B
CAS No.: 110351-91-2
Research Areas:
(R)-Exatecan Intermediate 1 is a key intermediate in the synthesis of Camptothecin (HY-16560) derivatives, and can be used to prepare Exatecan mesylate (DX8951f) (HY-13631A). (R)-Exatecan Intermediate 1 enables the synthesis of Exatecan, which exhibits low sensitivity to multidrug resistance and has great value in anti-tumor research .
Research Areas:
Hexamethylene bisacetamide (HMBA) is a differentiation inducer and selective bromine domain inhibitor that can differentiate across the blood-brain barrier. Hexamethylene bisacetamide can induce tumor cell differentiation and inhibit cell proliferation, showing antitumor activity. Hexamethylene bisacetamide induces apoptosis by Notch1, Bcl-2 and p53 signaling pathways. In addition, Hexamethylene bisacetamide improves the obesity phenotype of mice .
Cat. No.: HY-50097
CAS No.: 55289-36-6
Cat. No.: HY-W011238
CAS No.: 6110-53-8
Synonyms: (Z)-1-Bromooctadec-9-ene
Target:
Research Areas:
Oleyl bromide ((Z)-1-Bromooctadec-9-ene) is a hydrophobic compound that can carry out ring-opening reaction through a process called "encapsulation". Oleyl bromine can also be used as the starting material in the synthesis of oleylphosphonates.
Cat. No.: HY-163729
CAS No.: 2201082-98-4
Target:
Research Areas:
I-BET787 is a orally active BET bromine domain inhibitor with pIC50s of 7.1 and 5.9 for BRD4 BD1 and BRD4 BD2, respectively. I-BET787 has anti-inflammatory activity in mice .
Cat. No.: HY-W032015
CAS No.: 111-83-1
Synonyms: n-Octyl Bromide
Target:
Research Areas:
1-Bromooctane (n-Octyl Bromide) posesses a terminal bromine. The bromine is a very good leaving group for nucleophilic substitution reactions.
Cat. No.: HY-W016455
CAS No.: 4286-55-9
Target:
Research Areas:
6-Bromo-1-hexanol posesses a terminal bromine and hydroxylic group. The bromine is a very good leaving group for nucleophilic substitution reactions. The hydroxyl group enables further derivatization or replacement with other reactive functional groups.
Cat. No.: HY-W002668
CAS No.: 223463-13-6
Cat. No.: HY-W014159
CAS No.: 55289-35-5
Cat. No.: HY-W011972
CAS No.: 2758-06-7
Cat. No.: HY-W008629
CAS No.: 28290-41-7
Target:
Research Areas:
(E,E)-Farnesyl bromine is a synthetic substrate that is used to study the enzyme guanine nucleotide-binding protein (G protein) in vitro.
Cat. No.: HY-W190881
CAS No.: 2098982-00-2
Target:
Research Areas:
N3-PEG11-CH2CH2Br is a PEG linker containing a bromine and an azide group. The hydrophilic PEG spacer increases solubility in aqueous media. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. The bromine (Br) is a very good leaving group for nucleophilic substitution reactions.
Target:
Research Areas:
1,3-Dibromopropane (Trimethylene dibromide) is a dihaloalkane substrate. 1,3-Dibromopropane serves as a dehalogenation substrate for the haloalkane dehalogenase DmmA, and undergoes hydrolysis to remove bromine atoms. 1,3-Dibromopropane acts as an intermediate in organic synthesis .
Category:
Cat. No.: HY-W076740
CAS No.: 6974-78-3
Synonyms: 8-Bromo-9H-purin-6-amine
Cat. No.: HY-W007593
CAS No.: 7254-19-5
Cat. No.: HY-150239
CAS No.: 2097610-30-3
Synonyms: BAY-299N
Target:
Research Areas:
BAY-364 (BAY-299N) is an inhibitor of the second bromine domain in TAF1. BAY-364 inhibits the TAF1 of Kasumi-1 cells, CD34 + cells and K562 cells with IC50 values of 1.0 µM, 10.4 µM and 10.0 µM respectively .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
