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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
11 Results for "
buthionine sulfoximine
" in MedChemExpress (MCE) Product Catalog:
Products (11)
11 Results for "buthionine sulfoximine" in MCE Product Catalog:
37
37 Publications Verification
Synonyms: buthionine sulfoximine; BSO
Target:
Research Areas:
DL-Buthionine-(S,R)-sulfoximine is a potent inhibitor of glutamylcysteine synthetase biosynthesis.
37
37 Publications Verification
Cat. No.: HY-106376B
Purity: 99.09%
Synonyms: buthionine sulfoximine hydrochloride; BSO hydrochloride
Target:
Research Areas:
DL-Buthionine-(S,R)-sulfoximine hydrochloride (Buthionine sulfoximine hydrochloride) is a potent inhibitor of glutamylcysteine synthetase biosynthesis.
21
21 Cited Publications
Synonyms: L-buthionine sulfoximine; L-BSO
Target:
Research Areas:
L-Buthionine-(S,R)-sulfoximine is a cell-permeable, potent, fast acting and irreversible inhibitor of g-glutamylcysteine synthetase and depletes cellular glutathione levels. The IC50 value of L-Buthionine-(S,R)-sulfoximine on melanoma, breast and ovarian tumor specimens are 1.9 μM, 8.6 μM, and 29 μM, respectively.
21
21 Cited Publications
Cat. No.: HY-106376C
Purity: ≥98.0%
Synonyms: L-buthionine sulfoximine hydrochloride; L-BSO hydrochloride
Target:
Research Areas:
L-Buthionine-(S,R)-sulfoximine hydrochloride is a cell-permeable, potent, fast acting, orally active and irreversible inhibitor of g-glutamylcysteine synthetase and depletes cellular glutathione levels. The IC50 value of L-Buthionine-(S,R)-sulfoximine on melanoma, breast and ovarian tumor specimens are 1.9 μM, 8.6 μM, and 29 μM, respectively .
Cat. No.: HY-W101673
CAS No.: 2416-95-7
Target:
Research Areas:
Dipropofol is a dimeric derivative of Propofol (HY-B0649) with antioxidant and antibacterial activities. Dipropofol terminates free radical chain reactions, scavenges DPPH free radicals and inhibits lipid peroxidation. Dipropofol protects cells from death induced by glutamate, Aβ(25-35) and buthionine sulfoximine, and increases the survival rate of mice exposed to oxygen. Dipropofol selectively activates tonic GABAA currents, hyperpolarizes resting membrane potential, reduces action potential firing, and alleviates the severity of seizures induced by Kainic acid. Dipropofol can be used in the research of Gram-positive bacterial infections, Alzheimer's disease, cerebral ischemia-related neuronal injury, oxygen toxicity and temporal lobe epilepsy .
Cat. No.: HY-179561
CAS No.: 894430-68-3
Target:
Research Areas:
ACS14 is a derivative of Aspirin (HY-14654). ACS14 reduces Buthionine Sulfoximine (BSO) (HY-106376)-induced hypertension, plasma levels of thromboxane B2, 8-isoprostane, and insulin in rats, while GSH remained in the control range. ACS14 can be used for hypertension research .
Cat. No.: HY-106376BR
Synonyms: buthionine sulfoximine hydrochloride (Standard); BSO hydrochloride (Standard)
Target:
Research Areas:
DL-Buthionine-(S,R)-sulfoximine (hydrochloride) (Standard) is the analytical standard of DL-Buthionine-(S,R)-sulfoximine (hydrochloride). This product is intended for research and analytical applications. DL-Buthionine-(S,R)-sulfoximine hydrochloride (Buthionine sulfoximine hydrochloride) is a potent inhibitor of glutamylcysteine synthetase biosynthesis.
Cat. No.: HY-106376R
CAS No.: 5072-26-4
Synonyms: buthionine sulfoximine (Standard); BSO (Standard)
Target:
Research Areas:
DL-Buthionine-(S,R)-sulfoximine (Standard) is the analytical standard of DL-Buthionine-(S,R)-sulfoximine. This product is intended for research and analytical applications. DL-Buthionine-(S,R)-sulfoximine is a potent inhibitor of glutamylcysteine synthetase biosynthesis.
Cat. No.: HY-106376AR
CAS No.: 83730-53-4
Synonyms: L-buthionine sulfoximine (Standard); L-BSO (Standard)
Target:
Research Areas:
L-Buthionine-(S,R)-sulfoximine (Standard) is the analytical standard of L-Buthionine-(S,R)-sulfoximine (HY-106376A). This product is intended for research and analytical applications. L-Buthionine-(S,R)-sulfoximine is a cell-permeable, potent, fast acting and irreversible inhibitor of g-glutamylcysteine synthetase and depletes cellular glutathione levels. The IC50 value of L-Buthionine-(S,R)-sulfoximine on melanoma, breast and ovarian tumor specimens are 1.9 μM, 8.6 μM, and 29 μM, respectively.
Cat. No.: HY-W101673R
CAS No.: 2416-95-7
Research Areas:
Dipropofol (Standard) is the analytical standard of Dipropofol. This product is intended for research and analytical applications. Dipropofol is a dimeric derivative of Propofol (HY-B0649) with antioxidant and antibacterial activities. Dipropofol terminates free radical chain reactions, scavenges DPPH free radicals and inhibits lipid peroxidation. Dipropofol protects cells from death induced by glutamate, Aβ(25-35) and buthionine sulfoximine, and increases the survival rate of mice exposed to oxygen. Dipropofol selectively activates tonic GABAA currents, hyperpolarizes resting membrane potential, reduces action potential firing, and alleviates the severity of seizures induced by Kainic acid. Dipropofol can be used in the research of Gram-positive bacterial infections, Alzheimer's disease, cerebral ischemia-related neuronal injury, oxygen toxicity and temporal lobe epilepsy .
Cat. No.: HY-183406
CAS No.: 102616-62-6
Research Areas:
AS15 is a PDIA1 inhibitor with an IC50 value of 300 nM. AS15 interacts with the active-site cysteine of PDIA1, and this process is independent of the substrate-binding domain of PDIA1. AS15 acts as a synergistic cell growth inhibitor with buthionine sulfoximine (BSO) (HY-106376), a glutathione synthesis inhibitor. AS15 can be used in the research of glioblastoma .
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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
